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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Principles of Gender-Specific Medicine

      • 4th Edition
      • April 3, 2023
      • Marianne Legato J
      • English
      • Hardback
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      • eBook
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      Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine.
    • Artificial Intelligence in Capsule Endoscopy

      • 1st Edition
      • February 9, 2023
      • Miguel Mascarenhas + 2 more
      • English
      • Paperback
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      • eBook
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      Artificial Intelligence in Capsule Endoscopy: A Gamechanger for a Groundbreaking Technique highlights the importance of Artificial Intelligence (AI) application in capsule endoscopy. AI will have a key role in the mid/long-term for gastrointestinal endoscopy and capsule endoscopy. This field is a prime area for the use of AI tools with over 50,000 images per endoscopy capsule video, making video analysis a time and resource consuming task and prone to error. With the application of AI image analysis tools (primarily Convolutional Neural Networks) we can decrease capsule endoscopy video reading time and resources and greatly benefit diagnostic accuracy and patient outcomes. In 15 chapters, this important reference provides a global and comprehensive perspective from the background information of AI, machine learning, deep learning and their implications in GI endoscopy. It showcases AI practical use in lesion detection and in relevant clinical indications (like obscure gastrointestinal bleeding and inflammatory bowel disease), and points to future applications of AI within the field.
    • Metalloenzymes

      • 1st Edition
      • August 30, 2023
      • Claudiu T. Supuran + 1 more
      • English
      • Paperback
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      • eBook
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      Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.
    • Translational Interventional Radiology

      • 1st Edition
      • April 5, 2023
      • Adam E.M. Eltorai + 3 more
      • English
      • Paperback
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      • eBook
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      Translational Interventional Radiology, a volume in the Handbook for Designing and Conducting Clinical and Translational Research series, covers the principles of evidence-based medicine and applies these principles to the design of translational investigations in Interventional Radiology. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in Interventional Radiology, and know what is needed for successful collaboration. Further, this reference is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps aspiring investigators navigate challenging considerations in study design and implementation. This book provides valuable discussions of the critical appraisal of published studies in Interventional Radiology, elucidating the evaluation of the quality with respect to measuring outcomes and making effective use of all types of evidence in patient care. In short, this practical guide will be of interest to every medical researcher and interventional radiologist who has ever had a good clinical idea but not the knowledge of how to test it.
    • Rivers of North America

      • 2nd Edition
      • April 20, 2023
      • Michael D. Delong + 3 more
      • English
      • Paperback
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      • eBook
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      Rivers of North America, Second Edition features new updates on rivers included in the first edition, as well as brand new information on additional rivers. This new edition expands the knowledge base, providing readers with a broader comparative approach to understand both the common and distinct attributes of river networks. The first edition addressed the three primary disciplines of river science: hydrology, geomorphology, and ecology. This new edition expands upon the interactive nature of these disciplines, showing how they define the organization of a riverine landscape and its processes. An essential resource for river scientists working in ecology, hydrology, and geomorphology.
    • Multi-system Imaging Spectrum associated with Neurologic Diseases

      • 1st Edition
      • August 19, 2023
      • Bo Gao + 1 more
      • English
      • Hardback
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      • eBook
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      Multi-System Imaging Spectrum associated with Neurologic Diseases covers over 200 classic multi-systemic entities associated with neurologic diseases with detailed discussion alongside illustrative photos for memory aids and clarification. Accompanying text explains the history and meaning of the descriptive or metaphoric sign. Uniquely written from a practical point of view, each case leads you through a radiology expert’s thought process in analyzing imaging pitfalls of different organs or systems. The cases highlight clinical presentation, relevant pathology, anatomy, physiology, and pertinent imaging features of common disease processes. Key information is distilled succinctly, with bulleted, detailed illustrations and images.
    • The Transgender Athlete

      • 1st Edition
      • August 15, 2023
      • Amy M. West
      • English
      • Paperback
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      • eBook
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      The Transgender Athlete: A Guide for Sports Medicine Providers presents sports medicine practitioners insights into the unique issues and concerns of transgender athletes in order to help them understand rules regarding transgender athlete participation and learn how to better provide competent care to transgender athletes. There are over 1.4 million transgender adults in the United States. Transgender individuals undergo gender-affirming treatments including sex hormone therapy and gender-affirming surgery. An increasing number of transgender people are participating in sports and presenting to sports medicine clinics with injuries, yet there is little research about this athlete population. It is important that sports medicine providers understand the types of hormone treatments and surgeries and how these changes affect the musculoskeletal health of transgender people. Additionally, transgender people may require specific considerations when interacting with medical providers. Furthermore, sports medicine providers are often consulted to formulate transgender athlete inclusion policy. These policies are continuously changing, as new evidence becomes available, which may be difficult to understand without knowledge of the gender transition process.
    • MicroRNA in Regenerative Medicine

      • 2nd Edition
      • May 8, 2023
      • Chandan K. Sen
      • English
      • Hardback
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      • eBook
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      Regulating virtually all biological processes, the genome’s 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body’s toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence.
    • Ophthalmic Pathology

      • 1st Edition
      • March 28, 2023
      • Curtis E. Margo
      • English
      • Paperback
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      • eBook
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      Ophthalmic Pathology: The Evolution of Current Concepts examines how our current understanding of morphologic disease, nomenclature and classification over the last century came about. The book explores the historical context and the modern trends of ocular nosology, emphasizing the science of disease classification. Chapters highlight major studies and developments surrounding approximately 50 disorders whose diagnoses are established by pathology, corresponding to a historical road map of current nomenclature, methods of disease classification, and the role of diagnostic morphology. Using a streamlined, highly illustrated format, this book provides a unique historic and evolutionary perspective into current views on the morphology of eye disease.
    • Translational Glycobiology in Human Health and Disease

      • 1st Edition
      • November 29, 2023
      • Michelle Kilcoyne + 1 more
      • English
      • Paperback
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      • eBook
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      Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translatio... Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery.