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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Synthesis of 5-Membered Heterocycles

      • 1st Edition
      • September 12, 2023
      • Navjeet Kaur
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 4 2 3 4
      • eBook
        9 7 8 0 4 4 3 1 3 4 2 4 1
      Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units.

    • Therapy Resistance in Prostate Cancer

      • 1st Edition
      • Volume 20
      • October 24, 2023
      • Hisham Bahmad
      • English
      • Hardback
        9 7 8 0 4 4 3 1 6 0 3 2 5
      • eBook
        9 7 8 0 4 4 3 1 6 0 3 3 2
      • eBook
        9 7 8 0 4 4 3 3 5 0 5 0 4
      Therapy Resistance in Prostate Cancer: Mechanisms and Insights, Volume 20 highlights the main mechanisms that are responsible for therapy resistance in PCa allowing researchers and clinicians to have a synopsis of current options and therapies that can be proposed to overcome resistance. Understanding the mechanisms responsible for chemotherapy resistance helps researchers all over the world delve deeper into the pathways behind this resistance and potentially discover new therapeutic targets for PCa. Prostate cancer (PCa) is among the most diagnosed cancers in men worldwide, as well as one of the most common causes of cancer-related deaths.Despite the advances in treatment, the disease remains associated with poor survival and resistance to cytotoxic and targeted therapies.

    • Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC

      • 1st Edition
      • Volume 19
      • January 30, 2023
      • Anthony Faber
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 8 3 3 3
      • eBook
        9 7 8 0 1 2 8 2 2 8 3 4 0
      Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer.

    • Rigor and Reproducibility in Genetics and Genomics

      • 1st Edition
      • November 8, 2023
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 2 1 8 6
      • eBook
        9 7 8 0 1 2 8 1 7 2 1 9 3
      Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists.

    • Mesenchymal Stem Cells

      • 1st Edition
      • May 12, 2023
      • Leisheng Zhang + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 3 4 6 7
      • eBook
        9 7 8 0 3 2 3 9 5 8 4 9 3
      Mesenchymal Stem Cells: Biological Concepts, Current Advances, Opportunities and Challenges systematically summarizes and discusses the basic concepts and latest updates of mesenchymal stem cells (MSCs) in the past 60 years, as well as the latest progress of clinical translational research and regulatory policy at home and abroad, which will be of great practical significance for promoting and guiding the future development of stem cell production and regenerative medicine.

    • Conceptual Breakthroughs in The Evolutionary Biology of Aging

      • 1st Edition
      • July 10, 2023
      • Kenneth R. Arnold + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 5 4 5 6
      • eBook
        9 7 8 0 1 2 8 2 1 5 4 6 3
      Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field’s breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures.

    • Human Histology

      • 1st Edition
      • January 28, 2023
      • Bertalan Dudas
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 9 1 6
      • eBook
        9 7 8 0 3 2 3 9 8 4 9 6 6
      Visually engaging and easy to use, Human Histology: A Text and Atlas for Physicians and Scientists covers the normal histology of every organ in the human body. This book presents full-page high-definition photomicrographs for organs and tissues, followed by a compact and simple-to-read description of the structures identified on the micrographs, offering a clear, visual understanding of this complex subject. With over 300 outstanding images, this reference is an invaluable resource for every clinical researcher and pathologist in need of easily accessible, relatively simple but detailed enough information on normal histology of different organs systems. Due to its compact, but detailed layout, the volume is an excellent tool for medical board review and can be recommended for medical students and histology course directors.

    • Cancer Stem Cells and Signaling Pathways

      • 1st Edition
      • November 1, 2023
      • Surajit Pathak + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 2 1 2 4
      • eBook
        9 7 8 0 4 4 3 1 3 2 1 1 7
      Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression.

    • Biomarkers of Hip Implant Function

      • 1st Edition
      • January 10, 2023
      • Ilona Swiatkowska
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 5 9 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 7 4 2 9
      Nearly all orthopaedic surgeons have implanted a cobalt-chromium hip, and most general practitioners have at least one patient with a cobalt-chromium prosthesis on their books. The recent worldwide controversy surrounding metal-on-metal bearings – and increasing concern over the use of metallic biomaterials in general – means that advice on how to manage patients with metal implants is of great interest to these professionals. Specifically, they want to know if there are any diagnostic tests that could be performed to gain clues about implant performance and the risk of local or systemic toxicity. Biomarkers of Hip Implant Function aims to bring together all established and promising new biomarkers and critically evaluate their clinical usefulness. Researchers will benefit from an updated, comprehensive view of the topic to identify underexplored areas. Orthopaedic surgeons and general practitioners will use the book to monitor implant performance and manage their patients. The work may also benefit engineers and joint implant manufacturers by guiding improvements in implant design, and be of interest to regulators and policymakers to inform guidelines on the follow-up of hip implant recipients.

    • New Horizons in Natural Compound Research

      • 1st Edition
      • April 18, 2023
      • Surya Nandan Meena + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 2 3 2 0
      • eBook
        9 7 8 0 4 4 3 1 5 2 3 3 7
      New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas. From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment.

Related subjects

Biochemistry biophysics

Biotechnology

Endocrinology

Life sciences general

Molecular biology cellular biology and genetics

Physiology