Epigenetics in Health and Disease part B
- 1st Edition, Volume 198 - May 23, 2023
- Editors: Vijai Singh, Indra Mani
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 1 4 4 4 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 1 4 4 5 - 5
Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume pr… Read more
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- Presents the latest release in the Progress in Molecular Biology and Translational Science series
- Includes the latest information on Epigenetics in Health and Disease
- Cover
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Applications of bioinformatics in epigenetics
- Abstract
- 1: Introduction
- 2: Epigenetic data processing and analysis
- 3: Epigenetics databases
- 4: In silico tools for epigenetic modification
- 5: Conclusion and future perspectives
- Conflict of interest
- References
- Chapter Two: CRISPR-dCas9 system for epigenetic editing towards therapeutic applications
- Abstract
- 1: Introduction
- 2: Approaches of epigenome modification using CRISPR-dCas9
- 3: Conclusions and future remarks
- Acknowledgments
- References
- Chapter Three: Epigenetic control of heredity
- Abstract
- 1: Introduction
- 2: Epigenetic inheritance
- 3: Epigenetic control on gene expression
- 4: DNA methylation and heredity
- 5: Histone modifications and heredity
- 6: Non-coding RNAs and heredity
- 7: Factors influencing epigenesis, associated diseases and their inheritance
- 8: Role of epigenetic inheritance in heritability of diseases
- 9: Conclusions
- 10: Future perspective
- References
- Chapter Four: Epigenetics in renal diseases
- Abstract
- 1: Introduction
- 2: Epigenetic mechanisms in renal diseases
- 3: Conclusion and future perspectives
- Conflict of interest
- References
- Chapter Five: Epigenetics in cancer development, diagnosis and therapy
- Abstract
- 1: Introduction
- 2: Epigenetics and cancer development
- 3: Epigenetics and cancer diagnosis
- 4: Epigenetics and cancer therapy
- 5: Conclusion and future direction
- Acknowledgments
- References
- Chapter Six: Microbiota and epigenetics: Health impact
- Abstract
- 1: Introduction
- 2: Epigenetic processes
- 3: Interaction among diet, microbiome, and epigenetics
- 4: Epigenetics and microbiome in the diseased states
- 5: Therapeutic approaches
- 6: Conclusion
- 7: Future perspective
- References
- Chapter Seven: Histone deacetylase (HDACs) inhibitors: Clinical applications
- Abstract
- 1: Introduction
- 2: The roles of HDACs in cancer
- 3: HDAC inhibitors in neurodegenerative diseases
- 4: HDACi in cardiovascular diseases
- 5: Conclusions
- References
- Chapter Eight: Early epigenetic markers for precision medicine
- Abstract
- 1: Introduction
- 2: What is epigenetics?
- 3: Epigenetic modifications
- 4: Role of epigenetics in biological processes
- 5: Epigenetics in cancer
- 6: Epigenetic in neurological disorders
- 7: Conclusions
- References
- Chapter Nine: Epigenetics of neurological diseases
- Abstract
- 1: Introduction
- 2: Epigenetic layers and their regulators
- 3: Epigenetic dysregulation in neurological disorders
- 4: Therapeutic potential
- 5: Conclusion
- References
- Chapter Ten: Epigenetic regulons in Alzheimer's disease
- Abstract
- 1: Introduction
- 2: Epigenetic mechanisms
- 3: Environmental factors in the progression of AD
- 4: Epigenetic mechanisms in Alzheimer's disease (AD)
- 5: Epigenetic therapeutics in AD
- 6: Conclusions
- References
- Chapter Eleven: Epigenetics in epilepsy
- Abstract
- 1: Introduction
- 2: Epigenetic modifications in epilepsy
- 3: Therapeutic prospects
- 4: Conclusion
- References
- Index
- No. of pages: 292
- Language: English
- Edition: 1
- Volume: 198
- Published: May 23, 2023
- Imprint: Academic Press
- Hardback ISBN: 9780443214448
- eBook ISBN: 9780443214455
VS
Vijai Singh
Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.
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