Advances in Accelerators and Medical Physics

1st Edition - May 25, 2023
Editors: Toshiyuki Shirai, Teiji Nishio, Kiyokazu Sato
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 1 9 1 - 9
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 1 9 2 - 6

Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Ad… Read more

Advances in Accelerators and Medical Physics

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Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods.

SECTION A X-ray therapy and electron beam therapy

1. Electron accelerator and beam irradiation system

Mitsuhiro Yoshida and Kazutoshi Yabuta

2. External beam radiation therapy

Mitsuhiro Nakamura

3. Immobilization and patient positioning

Yusuke Tsuruta

4. Respiratory motion management

Dejun Zhou

5. Radiation treatment planning (photon and electron beam therapy)

Takanori Adachi

6. Dosimetric verification

Hideaki Hirashima

7. Adaptive radiotherapy

Hiraku Iramina

SECTION B Particle therapy

8. Proton cyclotron accelerator and line scanning irradiation system

Toshiki Tachikawa

9. Proton synchrotron accelerator and spot scanning irradiation system

Futaro Ebina

10. Carbon-ion synchrotron accelerator and raster scanning irradiation system

Kiyokazu Sato, Atsushi Miyamoto, Daisuke Kameda, and Shigeki Takayama

11. Quantum scalpel

Ken Katagiri, Kota Mizushima, and Saki Amano

12. Irradiation and therapy methods

Kenji Hotta and Hideyuki Mizuno

13. Management of patient position and respiratory motion

Seishin Takao and Shinichiro Mori

14. Treatment planning

Toshiyuki Toshito and Makoto Sakama

15. Dosimetric verification

Toshiyuki Toshito

16. Radiation protection

Shunsuke Yonai

SECTION C Boron neutron capture therapy (BNCT)

17. Principle and current status

Yoshinori Sakurai

18. Proton linear accelerator and lithium target system

Kenichi Kaneta and Masaru Nakamura

19. Proton linear accelerator and beryllium target system

Takashi Sugimura

20. Proton cyclotron accelerator and beryllium target system

Toshinori Mitsumoto

21. Irradiation method and the immobilization and positioning of patients (head and neck)

Takahiro Kato, Katsumi Hirose, Akihiko Takeuchi, Ryohei Kato, Shinya Komori, Tomoaki Motoyanagi, Mariko Sato, and Yoshihiro Takai

22. Therapy method, irradiation method, and immobilization and positioning of patients (brain)

Naonori Hu

23. Therapy method, irradiation method, and immobilization and positioning (skin)

Satoshi Nakamura

24. Treatment planning

Hiroaki Kumada

25. Dosimetric verification

Hiroki Tanaka

26. Future works

Yoshinori Sakurai

SECTION D Molecular imaging and therapy

27. Electron linear accelerator for medical radionuclide production

Jaewoong Jang

28. Cyclotron accelerators for the production of medical radionuclides

Tetsuo Kawama, Manami Taniguchi, Francisco Guerra Gomez, Takashi Oda, Jun Kato, Satoshi Ueno, Masanori Tachibana, Hiroki Higuchi, and Toru Ishizuka

29. Dosimetry in therapy using radiopharmaceuticals

Tetsuya Sakashita, Naoyuki Ukon, and Tatsuya Higashi

SECTION E Novel technologies

30. FLASH radiotherapy

Satoshi Kodaira and Teruaki Konishi

31. Laser-driven ion accelerator

Sadaoki Kojima and Masayasu Hata

Toshiyuki Shirai

Dr. Toshiyuki Shirai is the Director of the Department of Accelerator and Medical Physics at the National Institutes for Quantum and Radiological Science and Technology (QST). He received his PhD degree from the Faculty of Science, Kyoto University. After graduation, he worked in the accelerator and beam physics at the Institute for Chemical Research, Kyoto University. At QST, his research interests are in medical physics and medical accelerators for particle therapy, especially carbon-ion radiotherapy. He has served as a Councilor of the Particle Accelerator Society of Japan.

Affiliations and expertise

Director, Department of Accelerator and Medical Physics, Institute for Quantum Medical Science, National Institute for Quantum Science and Technology, Chiba, Japan

Teiji Nishio

Dr. Teiji Nishio is Professor and Director of the Medical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan. He received his Ph.D. in Science from the Department of Physics, Graduate School of Science, Rikkyo University for his research in nuclear astrophysics. He also received his Ph.D. in Medicine from the Department of Biophysics and Medicine, Graduate School of Medicine, The University of Tokyo for his research in medical physics. So far, he has been working on research and development of proton therapy, especially, Beam On-Line PET system, which visualize the proton irradiation area, at the National Cancer Center Japan. He is currently engaged in research and education on X-ray therapy, proton therapy, and heavy particle therapy in the Medical Physics Laboratory at Osaka University. He is also a board member of the Japan Society of Medical Physics (JSMP).

Affiliations and expertise

Professor and Director of the Medical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan.

Kiyokazu Sato

Kiyokazu Sato is the Senior Consultant of Keihin Product Operations Toshiba Energy Systems & Solutions Corporation. He is responsible for improving technologies and the quality of Keihin Product Operations which is the core factory in Toshiba for energy related equipments such as steam and hydro turbines, turbine-generators, heat exchangers, nuclear reactor internals and new energy equipment. Prior to his current role, he was the Senior Manager of Machinery and Equipment Department and in charge of designing and fabricating new energy equipment such as particle accelerators, superconducting magnets, equipment for fusion reactors, and special remote handling systems. Dr. Sato holds a PhD in Engineering for his work on heavy ion linear accelerators from Tokyo Institute of Technology, Tokyo, Japan.

Affiliations and expertise

Senior Consultant, Keihin Product Operations, Toshiba Energy Systems & Solutions Co., Kanagawa, Japan