Back to School Savings: Save up to 30% on print books and eBooks. No promo code needed.
Back to School Savings: Save up to 30%
The Science of Glaucoma Management
From Translational Research to Next-Generation Clinical Practice
1st Edition - May 18, 2023
Editors: Kevin Gillmann, Kaweh Mansouri
Paperback ISBN:9780323884426
9 7 8 - 0 - 3 2 3 - 8 8 4 4 2 - 6
eBook ISBN:9780323884433
9 7 8 - 0 - 3 2 3 - 8 8 4 4 3 - 3
The Science of Glaucoma Management: From Translational Research to Next-Generation Clinical Practice bridges the gap between laboratory research and clinicians by bringing the… Read more
Purchase Options
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
The Science of Glaucoma Management: From Translational Research to Next-Generation Clinical Practice bridges the gap between laboratory research and clinicians by bringing the latest promising research directly from researchers to clinicians long before they translate into clinical advances, and often before they are presented at conferences. Organized as a series of clinically relevant topics written by world-leading experts, this book summarizes the current state of laboratory and translational research and draws on the potential implications for day-to-day clinical practice. It offers new insights and mind-opening statements through contributions from some of the most respected glaucoma research groups. The book allows glaucoma specialists to explore novel ways to refine and rethink their practice based on the latest discoveries in basic sciences and breakthrough technologies, and to gain a better understanding on how their specialty is evolving and how research may shape tomorrow’s practice.
Presents a detailed report on the latest translational research and breakthroughs that may transform glaucoma practice
Overviews the specialty from a scientific and clinical point-of-view
Written by world-renowned clinicians and researchers in the field of glaucoma
Includes insights, opinions and recommendations from some of the most prominent scientists and ophthalmologists
Covers hot topics and the latest technologies in glaucoma, such as minimally invasive glaucoma surgery, telemedicine, gene therapy, neuroprotection and artificial intelligence
Glaucoma researchers, glaucoma specialists who seek to understand the basic sciences underlying recent and future breakthrough in their specialty, and to refine their clinical practice, General ophthalmologists seeking to vastly deepen their knowledge of glaucoma management, Bioengineering and physiological research scientists, both established and in training, seeking to work in the field of glaucoma will constitute a secondary market
Cover image
Title page
Table of Contents
Copyright
Dedication
List of contributors
Foreword
Preface
Section 1: Currently accepted glaucoma practice
Chapter 1. Glaucoma pathology
Abstract
1.1 Quick reference summary
1.2 Introduction to glaucomatous pathology
1.3 Causes of glaucomatous pathology (linking ocular hypertension to optic nerve degeneration)
1.4 The processes of neurodegeneration
1.5 Unmet needs
References
Chapter 2. Epidemiology of glaucoma
Abstract
2.1 Quick reference summary
2.2 Global epidemiology of glaucoma
2.3 New trends in glaucoma epidemiology
2.4 Discussion
References
Chapter 3. Diagnosis and investigations in glaucoma
Abstract
3.1 Quick reference summary
3.2 Conclusion
References
Chapter 4. Follow-up
Abstract
4.1 Quick reference summary
4.2 Intraocular pressure and general considerations
4.3 Optic nerve head and retinal nerve fiber layer
4.4 Visual field
References
Chapter 5. Glaucoma management
Abstract
5.1 Quick reference summary
5.2 Aims of management
5.3 Management protocol
5.4 First-line treatments
5.5 Surgical options
5.6 Angle-closure glaucoma
References
Chapter 6. Section summary: into the unknown—identifying the needs
Abstract
6.1 Glaucoma detection and screening
6.2 Early diagnosis and identification of progression
6.3 Pressure-independent treatments
6.4 Minimally invasive glaucoma surgery
6.5 Pathophysiology and biomarkers
6.6 Patient-centered care and personalized medicine
Section 2: Pathophysiology and investigation methods
Chapter 7. Considerations for an effective screening program for glaucoma
Abstract
7.1 Quick reference summary
7.2 Review of accepted practice
7.3 Considerations for an effective screening program
7.4 Discussion and conclusion
References
Chapter 8. Vascular health and glaucoma
Abstract
8.1 Quick reference summary
8.2 Review of the currently accepted knowledge
8.3 Novel concepts on vascular factors in glaucoma
8.4 Discussion on current and future implications
8.5 Conclusion
References
Chapter 9. The role of circadian and extrinsic intraocular pressure fluctuations
Abstract
9.1 Introduction
9.2 Research and technological advancements
9.3 Implications in clinical practice
References
Chapter 10. Pseudoexfoliative glaucoma: epidemiology, pathophysiology, and clinical implications
Abstract
10.1 Quick reference summary
10.2 Introduction
10.3 Epidemiology
10.4 Pathophysiology
10.5 Clinical implications
10.6 Conclusions and perspective
References
Chapter 11. Angle-closure glaucoma: epidemiology, pathophysiology, and clinical impact
Abstract
11.1 Quick reference summary
11.2 Overview
11.3 Novel concepts/promising research
11.4 Discussion
References
Chapter 12. The role of optical coherence tomography angiography in glaucoma
Abstract
12.1 Quick reference summary
12.2 Introduction
12.3 Optical coherence tomography angiography in glaucoma
31.2 Definitions of intraocular pressure fluctuation
31.3 Intraocular pressure fluctuation, therapeutic response, and glaucoma progression
31.4 Conventional intraocular pressure assessment
31.5 Home intraocular pressure monitoring
31.6 New technologies
31.7 Conclusion
References
Chapter 32. Cyclophotocoagulation: a look at the history, the accepted norm, and the future possibilities
Abstract
32.1 Quick reference summary
32.2 Introduction (the conventional)
32.3 The new era
32.4 Future implications
References
Chapter 33. Section summary: determination of the ideal patient–surgeon–procedure match
Abstract
33.1 Minimally invasive glaucoma surgeries and devices factors
33.2 Surgeon factors
33.3 Patient factors
References
Section 5: New technologies
Chapter 34. Artificial intelligence and big data: technical considerations and clinical applications
Abstract
34.1 Quick reference summary
34.2 Artificial intelligence and glaucoma
34.3 Current state of artificial intelligence and big data
34.4 Future obstacles
References
Chapter 35. Detection of apoptosing retinal cells in glaucoma
Abstract
35.1 Quick reference summary
35.2 Currently accepted practice
35.3 Recent developments
35.4 Discussion
35.5 Conclusion
References
Chapter 36. Neuroprotection and neuroenhancement
Abstract
36.1 Quick reference summary
36.2 Neuroprotection in current clinical practice
36.3 Promising advances in neuroprotection
36.4 Potential applications
References
Chapter 37. Clinical trials in neuroprotection: special considerations
Abstract
37.1 Quick reference summary
37.2 Historical approaches in glaucoma clinical trials
37.3 Special considerations for neuroprotection trials
37.4 Summary
References
Chapter 38. Neuro-regeneration and stem-cell therapies
Abstract
38.1 Quick reference summary
38.2 Introduction
38.3 Optic nerve regeneration
38.4 Stem-cell therapies
38.5 Summary
Acknowledgments
References
Chapter 39. Genetic testing and gene therapy in glaucoma
Abstract
39.1 Quick reference summary
39.2 Impact of current knowledge of glaucoma family history on risk assessment and therapeutic approach
39.3 Role for genetic testing and gene-based therapies in glaucoma risk assessment and treatment
39.4 Implications for clinical practice and impact on future glaucoma care
References
Chapter 40. Conclusion: glaucoma, moving forward
Abstract
Index
No. of pages: 482
Language: English
Published: May 18, 2023
Imprint: Academic Press
Paperback ISBN: 9780323884426
eBook ISBN: 9780323884433
KG
Kevin Gillmann
Dr Kevin Gillmann is an ophthalmologist, glaucoma specialist and researcher. He shares his clinical work between Geneva and London, where he is an honorary fellow of Moorfields Eye Hospital. He graduated from Newcastle University Medical School in 2013 (MBBS) and became a Fellow of the European Board of Ophthalmologists in 2018. In 2019, he completed his residency within Professor André Mermoud's glaucoma unit and graduated a Medical Doctorate (MD) on Minimally-Invasive Glaucoma Surgery (MIGS) from the University of Lausanne.
His research with Stanford University and the Swiss Glaucoma Research Foundation focuses primarily on minimally invasive glaucoma surgery, neuroprotection and personalised glaucoma therapies. His work was featured on the frontpage of several magazines and in high-impact journals such as Nature's Eye and the British Journal of Ophthalmology, and received grants from the BrightFocus Foundation. With over 50 peer-reviewed articles, contributions to several book chapters and international guidelines, he was recently ranked amongst the top 0.5% glaucoma experts worldwide by ExpertScape.
Dr Gillmann frequently gives lectures both nationally and internationally, including at the University of Liverpool and the University of London, where he was awarded a prize for academic achievements. Aside from his activities as a clinicians and educator, Dr Gillmann has also devoted some of his research to the study and improvement of patient experience in healthcare services. He was awarded a postgraduate certificate in Media and Medicine from Harvard Medical School, a Master of Business Administration (MBA) with distinctions from the University of London, and a Master of Architecture from the University of Paris LaVillette where he wrote a thesis on the interconnections between hospital design, patient perception and society.
Affiliations and expertise
Glaucoma fellow at Moorfields Eye Hospital, London, UK, and a research coordinator at the Glaucoma Research Centre with the Swiss Glaucoma Research Foundation, Lausanne, Switzerland
KM
Kaweh Mansouri
Prof. Mansouri is currently a consultant ophthalmologist at Montchoisi Clinic, Lausanne, Switzerland; and an Adjoint Professor at the Department of Ophthalmology in University of Colorado School of Medicine, Denver, USA. He pioneered the use of 24-hour IOP-monitoring technology for patients with glaucoma by contributing to the development of the IOP-sensing contact lens, Triggerfish, and was the first ophthalmologist to give a TEDx talk. A MIGS pioneer, Kaweh leads many instructional courses at international meetings and has over 75 peer-reviewed publications, including several high-profile publications and journal covers. He has contributed to a number of glaucoma textbooks, including the World Glaucoma Association Consensus Series. Prof. Mansouri is also President of the Swiss Glaucoma Research Foundation, Executive Vice President of the World Glaucoma Association, and Glaucoma Editor of the Asia-Pacific Journal of Ophthalmology.
Affiliations and expertise
consultant ophthalmologist at Montchoisi Clinic, Lausanne, Switzerland; and an Adjoint Professor at the Department of Ophthalmology in University of Colorado School of Medicine, Denver, USA