Books in Molecular biology cellular biology and genetics

Population Genomics in the Developing World

1st Edition
November 10, 2024
Marlo Möller + 2 more
English
Paperback
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eBook
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Population Genomics in the Developing World: Concepts, Applications, and Challenges, a new volume in the Translational and Applied Genomics series, provides a comprehensive, up-to-date summary of the field of population genomics in developing countries. This book equips students, researchers, and clinicians with the practical skills and approaches necessary to face the unique challenges and opportunities of practicing population genomics in developing countries. Following a brief foundational overview, more than a dozen authors working in developing nations share applied case studies from the field, including rationale, methods, analysis, and outcomes to reinforce understanding. Key themes across the country-specific chapters include efficient genetic data generation and effective computational and statistical tools to analyze population-level data. This book then discusses clinical interpretation of these data, from direct-to-consumer ancestry testing to translational and applied precision medicine. A final chapter considers the ethical aspects of conducting genomic research in developing countries.

Immuno-oncology and immunotherapy Part B

1st Edition
Volume 190
November 7, 2024
Lorenzo Galluzzi + 2 more
English
Hardback
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eBook
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Immuno-Oncology And Immunotherapy – Part B Volume 190, in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. In this update, chapters include Machine learning methods to assess metastatic burden, Development of pre-clinical models, Tumor microenvironment analysis by multiparametric flow cytometry or/and mass cytometry, Measure of therapy induced cell senescence, and much more.

Nongenetic Information and Evolution

1st Edition
November 6, 2024
Nelson R Cabej
English
Paperback
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eBook
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Nongenetic Information and Evolution investigates the origin and nature of nongenetic information and its role in the mechanisms of evolutionary change. This book opens with an introduction to the theoretical background and forms of nongenetic information, alongside its relationship with genetic information. It then explores nongenetic information across the biological kingdoms, including animals, nonneural organisms, plants, and unicellulars.It also covers epigenetics as a form of nongenetic information, exploring DNA methylation, histone modifications, chromatin remodeling, and miRNA expression in this context. This book closes with a discussion of nongenetic information in evolution, considering evidence demonstrating its inheritance and hereditary impact.This book provides a detailed overview of the origin and evolutionary impact of nongenetic inheritance, delivering a basis for further understanding the occurrence of hereditary phenomena and transgenerational phenotypic changes that do not involve genes. This is a useful reference for researchers in the field of epigenetics, evolutionary biology, developmental biology, and cellular and molecular biology.

Substance P

1st Edition
November 6, 2024
Robert Vink
English
Paperback
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eBook
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Substance P: From Pain to Cancer, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, provides a complete discussion of substance P biology, its role in normal physiology and a variety of diseases.The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.

Metagenomics

2nd Edition
November 5, 2024
Muniyandi Nagarajan
English
Paperback
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eBook
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Metagenomics: Perspectives, Methods, and Applications, second edition, provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments and clinical settings. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians, and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case study-based application chapters include topics ranging from metagenome tools, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. This new edition has been fully updated to address the rapid growth and development of metagenomics applications, featuring expert discussion of recent developments and fresh case studies. Newly added chapters instruct in methods and implications of metagenomics in areas of growing focus, such as microbiome research, clinical diagnosis, metagenomic epidemiology, and plant microbe interaction. Data analysis is explained in simple terms for effective use of computational tools, software, and sequencing pipelines.

Machine Learning Models and Architectures for Biomedical Signal Processing

1st Edition
November 5, 2024
Suman Lata Tripathi + 3 more
English
Paperback
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eBook
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Machine Learning Models and Architectures for Biomedical Signal Processing presents the fundamental concepts of machine learning techniques for bioinformatics in an interactive way. The book investigates how efficient machine and deep learning models can support high-speed processors with reconfigurable architectures like graphic processing units (GPUs), Field programmable gate arrays (FPGAs), or any hybrid system. This great resource will be of interest to researchers working to increase the efficiency of hardware and architecture design for biomedical signal processing and signal processing techniques.

Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data

1st Edition
October 26, 2024
Anton Buzdin
English
Paperback
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eBook
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The field molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. Molecular Pathway Analysis Using High-Throughput OMICS Data contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data analysis in real-world research practice are given. Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data also focuses on the pathway analysis applications for solving tasks in biotechnology, pharmaceutics, and molecular diagnostics It demonstrates how pathway analysis can be applied for the research and treatment of chronic and acute diseases, for next-generation molecular diagnostics, for drug design and preclinical testing; relevant real-world examples, molecular tests, and web resources will be reviewed in-depth. The book shows a tendency of erasing the borders between chemistry, physics, informatics, mathematics, biology, and medicine by means of novel research approaches and instruments, providing a truly multidisciplinary approach.

Nature-Inspired Sensors

1st Edition
October 23, 2024
Hossam Haick
English
Paperback
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eBook
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Nature-Inspired Sensors presents and discusses the basic principles and latest developments in nature-inspired sensing and biosensing materials as well as the design and mechanisms for analyzing their potential in multifunctional sensing applications.The book starts with a comprehensive review of certain fundamental mechanisms in different living creatures, including humans, animals, and plants. It presents and discusses ways for imitating various nature-inspired structural features and their functional properties, such as hierarchical, interlocked, porous, and bristle-like structures and hetero-layered brick-and-mortar structures.It also highlights the utility of these structures and their properties for sensing functions, which include static coloration, self-cleaning, adhesive, underwater navigation and object detection, electric charge generation, and sensitive olfactory functions for detecting various substances. This is followed by an appraisal of accumulating knowledge and its translation from the laboratory to the point-of-care phase, using selective sensors as well as desktop and wearable artificial sensing devices, for example, electronic noses and electronic skins, in conjunction with AI-assisted data processing and decision-making in the targeted field of application.In addition, the book offers an insight into the challenges of continuing the development of nature-inspired smart sensing and biosensing technology and their wider availability, which can be substantially improved. It is a valuable reference for graduates, undergraduates, researchers, and working professionals in the fields of chemistry, materials science, and biomedical and environmental science.

Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

7th Edition
October 22, 2024
Reed E. Pyeritz + 2 more
English
Hardback
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eBook
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**Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Clinical Genetics**For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for students, health providers, and researchers involved in the care of patients with genetic conditions, and increasingly, all areas of health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals related to the applications of medical genetics and genomics across the full spectrum of inherited disorders and applications to medicine more broadly.In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to developmental disorders, as well as genetic conditions that affect hearing and vision. Here genetic researchers, students, and health professionals will find new and fully revised chapters on human developmental genetics, disorders affecting craniofacial development, chromosomal abnormalities, including aneuploidies and structural abnormalities, hereditary hearing impairment, and various genetic conditions of the eye.With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics, Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers.

Genetic Disease Discovery and Therapeutics

1st Edition
October 22, 2024
Moyra Smith
English
Paperback
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eBook
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Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders.This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disease Discovery and Therapeutics is a valuable reference for scientists and graduate students involved in laboratory research related to genetics, physiology, pathology, and pharmacology as well as clinicians who encounter patients with genetic disorders.

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