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Substance P
From Pain to Cancer
- 1st Edition - November 6, 2024
- Editor: Robert Vink
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 2 1 9 4 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 2 1 9 5 - 8
Substance P: From Pain to Cancer, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, provides a complete discussion of substance P biology,… Read more
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Request a sales quoteSubstance P: From Pain to Cancer, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, provides a complete discussion of substance P biology, its role in normal physiology and a variety of diseases.
The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.
Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.
The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.
Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.
- Provides a comprehensive overview of the role of substance P across different organ systems, including the nervous, cardiovascular and musculoskeletal systems and renal function
- Includes detailed coverage of the specific actions of substance P in various disease states and conditions, such as inflammation, cancer, acute brain injury, mood disorders, Parkinson’s disease, Alzheimer’s disease and viral infection including COVID-19
- Examines substance P as a modulator of the immune response and pain perception
- Includes expertise from a range of interdisciplinary areas including molecular biology, pharmacology, physiology, neuroscience, anatomy, and therapeutics
From graduate students to expert level.
1. The synthesis, release, and binding of substance P
Brendan A. Hilliard, Robert Vink, and Mary F. Barbe
2. Distribution of substance P receptors in mammals
Honoo Satake, Akira Shiraishi, and Tsuyoshi Kawada
3. Substance P in nonmammalian biology: Evolutionarily conserved tachykinin signaling
Dick R. Nassel
4. Methodological foundations of substance P detection
Nuray Erin
5. Substance P receptor antagonists
Francisco D. Rodrıguez and Rafael Covenas
6. Substance P in the cardiovascular system
Magdalena Chottova Dvorakova and Shashank Pandey
7. Substance P in lower urinary tract function and dysfunction
Mitsuharu Yoshiyama
8. Role of the substance P in learning and memory
Natalia Favila and Paul G. Overton
9. Substance P in nausea and vomiting
Paul L.R. Andrews, John A. Rudd, and Gareth J. Sanger
10. Substance P in the central control of respiration
Nicholas J. Burgraff and Jan-Marino Ramirez
11. Substance P in bone metabolism
Tanja Niedermair and Susanne Grassel
12. Life without substance P: The naked mole rat
Aishi Zhao, Jiwon Lee, Weronika Gryszkiewicz, and Thomas J. Park
13. Substance P in inflammation
Sophie E. Sipprell and Ian Marriott
14. Substance P in oxidative stress
Seyed Isaac Hashemy and Safieh Ebrahimi
15. Substance P in pain
Robert Vink
16. Substance P in cancer
Miguel Munoz, Marisa Rosso, Riffat Mehboob, and Francisco Esteban
17. Substance P in cardiac dysfunction
Scott P. Levick and Alexander Widiapradja
18. Substance P in neurotrauma
Rebecca George, Justin Krieg, and Frances Corrigan
19. Substance P in stroke
Annabel Sorby-Adams
20. Substance P in Alzheimer’s and Parkinson’s disease
Severini Cinzia
21. Substance P receptor antagonists for major depressive disorder
Nadia M.J. Rupniak and Mark S. Kramer
22 From a putative antidepressant to a validated mouse model of ADHD via NK1 receptors
S.C. Stanford
23. Substance P in stress and anxiety
Karl Ebner and Nicolas Singewald
24. Substance P-neurokinin 1 receptor pathway in musculoskeletal disorders
Brendan A. Hilliard and Mary F. Barbe
25. Substance P and sudden infant death syndrome (SIDS)
F. Bright, Robert Vink, and R.W. Byard
26. Immunobiology and pharmacology of neuropeptide substance P
Ehsan Aslam, Asina Gijasi, Caroline Perner, Rob van Wijk, Anne-Grete Martson, Gerard J.P. van Westen, Ilze Bot, Laura H. Heitman, and Alireza Mashaghi
27. Substance P in viral diseases—Especially coronavirus disease
Riffat Mehboob, Mariam Hashim, and Miguel Munoz
28. Substance P: Perspectives and future directions
Robert Vink
Brendan A. Hilliard, Robert Vink, and Mary F. Barbe
2. Distribution of substance P receptors in mammals
Honoo Satake, Akira Shiraishi, and Tsuyoshi Kawada
3. Substance P in nonmammalian biology: Evolutionarily conserved tachykinin signaling
Dick R. Nassel
4. Methodological foundations of substance P detection
Nuray Erin
5. Substance P receptor antagonists
Francisco D. Rodrıguez and Rafael Covenas
6. Substance P in the cardiovascular system
Magdalena Chottova Dvorakova and Shashank Pandey
7. Substance P in lower urinary tract function and dysfunction
Mitsuharu Yoshiyama
8. Role of the substance P in learning and memory
Natalia Favila and Paul G. Overton
9. Substance P in nausea and vomiting
Paul L.R. Andrews, John A. Rudd, and Gareth J. Sanger
10. Substance P in the central control of respiration
Nicholas J. Burgraff and Jan-Marino Ramirez
11. Substance P in bone metabolism
Tanja Niedermair and Susanne Grassel
12. Life without substance P: The naked mole rat
Aishi Zhao, Jiwon Lee, Weronika Gryszkiewicz, and Thomas J. Park
13. Substance P in inflammation
Sophie E. Sipprell and Ian Marriott
14. Substance P in oxidative stress
Seyed Isaac Hashemy and Safieh Ebrahimi
15. Substance P in pain
Robert Vink
16. Substance P in cancer
Miguel Munoz, Marisa Rosso, Riffat Mehboob, and Francisco Esteban
17. Substance P in cardiac dysfunction
Scott P. Levick and Alexander Widiapradja
18. Substance P in neurotrauma
Rebecca George, Justin Krieg, and Frances Corrigan
19. Substance P in stroke
Annabel Sorby-Adams
20. Substance P in Alzheimer’s and Parkinson’s disease
Severini Cinzia
21. Substance P receptor antagonists for major depressive disorder
Nadia M.J. Rupniak and Mark S. Kramer
22 From a putative antidepressant to a validated mouse model of ADHD via NK1 receptors
S.C. Stanford
23. Substance P in stress and anxiety
Karl Ebner and Nicolas Singewald
24. Substance P-neurokinin 1 receptor pathway in musculoskeletal disorders
Brendan A. Hilliard and Mary F. Barbe
25. Substance P and sudden infant death syndrome (SIDS)
F. Bright, Robert Vink, and R.W. Byard
26. Immunobiology and pharmacology of neuropeptide substance P
Ehsan Aslam, Asina Gijasi, Caroline Perner, Rob van Wijk, Anne-Grete Martson, Gerard J.P. van Westen, Ilze Bot, Laura H. Heitman, and Alireza Mashaghi
27. Substance P in viral diseases—Especially coronavirus disease
Riffat Mehboob, Mariam Hashim, and Miguel Munoz
28. Substance P: Perspectives and future directions
Robert Vink
- No. of pages: 550
- Language: English
- Edition: 1
- Published: November 6, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443221941
- eBook ISBN: 9780443221958
RV
Robert Vink
Robert Vink is an Emeritus Professor at the University of South Australia and is currently Chair of the Board for Connectivity: Traumatic Brain Injury Australia. He was previously appointed as the Professor and Chair of Neurosurgical Research and Head of School, Medical Sciences at the University of Adelaide, Australia. Throughout his time as a teaching/research academic he led a highly productive research group and maintained an extensive publication output. He is the author of over 260 articles and book chapters. He has supervised more than 30 graduate research students, many of whom now hold significant academic and other positions throughout Australia and internationally.
He is known internationally for his work in traumatic brain injury and has received numerous prestigious awards and appointments related to this. He currently provides research consulting services to universities and the pharmaceutical industry.
Affiliations and expertise
Consultant (Biotechnology, Legal, Higher Education) Vink NeuroConsulting, Mylor, AustraliaRead Substance P on ScienceDirect