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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Nutritional Epigenomics

    • 2nd Edition
    • Volume 14
    • English
    Nutritional Epigenomics, Second Edition, Volume Fourteen in the Translational Epigenetics series, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes.Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field.

  • Cytoskeletal Proteins in Neurodegenerative Diseases

    • 1st Edition
    • Volume 150
    • English
    Cytoskeletal Proteins in Neurodegenerative Diseases" provides a comprehensive overview of the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS).

  • Epigenetic Regulation of Cancer - Part E

    • 1st Edition
    • Volume 400
    • English
    Epigenetic Regulation of Cancer, Part E, Volume 400 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Revisiting Epigenetic Regulation in Cancer: Evolving Trends and Translational Implications, Epigenetic Alteration in Cervical Cancer Induced by Human Papillomavirus, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, Role of miRNAs as epigenetic regulators of immune checkpoints in lung cancer immunity, and much more.Other chapters cover The translational potential of epigenetic modulatory bioactive phytochemicals as adjuvant therapy against cancer, Strategies for improving chemotherapeutic sensitivity and the epigenetic regulation of doxorubicin resistance, and more.

  • Cell Shape and Position during Development

    • 1st Edition
    • Volume 166
    • English
    Cell Shape and Position during Development, Volume 166 provides a comprehensive overview of the fundamental roles that cell morphology and spatial organization play in the development of multicellular organisms. This volume brings together leading experts in developmental biology, cell biology, and biophysics to explore how cells acquire specific shapes. Chapters in this new release include Cell shape changes during sperm-egg interactions, Cell shape and position during organ development, Regulation of shape and position during asymmetric cell division, Cell shape dynamics during mouse peri-implantation development and embryo dormancy, Shaping the intestine: the role of cell morphology and spatial dynamics in development, and more.Additional sections Intermediate filaments in cell shape and position, Regulation of adult stem cell behavior by cytoskeletal dynamics and cell shape, Shape changes in gastrulation, and more.

  • Stem Cell-Mediated Regulation of Pyroptosis

    • 1st Edition
    • Debalina Bhattacharya + 1 more
    • English
    Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells before delving into the interaction across various conditions, ranging from cerebral injury, spinal injury, cardiac injury, osteoarthritis, cancer, and more. Users will find the latest research and future directions in the study of stem cells and pyroptosis, thus enabling further understanding of the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. Therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions are also considered, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics, and other related fields.

  • Lipids and Membranes: Detection by Imaging and Lipidomics

    • 1st Edition
    • Volume 726
    • English
    Lipids and Membranes: Detection by Imaging and Lipidomics, Volume 727 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the chapters in this new release include Measurement of fatty acid esters of hydroxy fatty acids, Superresolution organelle imaging with lipophilic HIDE probes, Ultra-high resolution analysis of membrane lipids from 15N metabolically labeled mice, Superresolution lipid imaging with expansion microscopy, High-resolution phosphoinositide analysis in healthy versus disease cells, and much more.Additional chapters focus on Alkyne lipids as tracers of lipid metabolism, Imaging oxidative stress in biomembranes, Imaging the dynamics of phosphatidylinositol 4-phosphate metabolism, Lipidomics for studying sphingolipids in cell death, Non-invasive imaging of phosphoinositides with genetically encoded lipid biosensors, Profiling lipotypes at the single cell level in heterogenous populations, MS imaging of phosphoinositides, and much more.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1st Edition
    • Volume 221
    • English
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • Live Biotherapeutics: Advancing Microbial Medicine

    • 1st Edition
    • Volume 220
    • English
    Microbial therapeutics are rapidly reshaping modern medicine, with live biotherapeutics emerging as a promising frontier. By harnessing the power of beneficial microbes, these innovative treatments offer new hope for conditions that resist conventional drugs, including metabolic disorders and antimicrobial-resist... infections. As the demand for safer, more effective alternatives grows, understanding this field becomes increasingly vital. The upcoming book, Live Biotherapeutics: Advancing Microbial Medicine, will provide a comprehensive and accessible overview of the science, applications, and future potential of live biotherapeutics in transforming healthcare.

  • Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer - Part B

    • 1st Edition
    • Volume 399
    • English
    Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part B delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Liquid biopsy approaches to capture minimal residual disease and therapy response in patients with early stage cancers, Identification of circulating biomarkers for cancer therapy-related cardiovascular toxicity, Extracellular Vesicles as Dynamic Biomarkers: Monitoring Therapeutic Responses and Drug Resistance in Cancer, and more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

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