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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Probiogenomics and Probiomics

    Concepts, Techniques, Applications, and Achievements
    • 1st Edition
    • June 1, 2026
    • Debmalya Barh + 1 more
    • English
    Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.

  • Advances in Biosystems

    • 1st Edition
    • June 1, 2026
    • Xiaoli Li + 2 more
    • English
    Advances in Biosystems investigates the latest techniques for evaluating, detecting, measuring, and enhancing the functional bioactivities, chemical composition, and physicochemical characteristics of animal, plant, and environmental biosystems. This comprehensive, interdisciplinary handbook provides detailed explanations for tracking functional molecules during various biological processes, along with practical methodologies for both laboratory and industrial applications. Sections cover cellular biosystems advances, including single-cell microsystems and tissue system biology of plants and animals, alongside biomass microsystems and agricultural biosystems advances, exploring innovations in animal, plant, and crop biosystems, as well as food hydrocolloids and biotechnological advancements.Additio... content addresses environmental biosystems, discussing colloidal biosystems, nano and micro-biosystems, chemical toxicology, eco-friendly biosystems, and green chemistry, pharmaceutical biosystems, highlighting medical biosystems, human cellular metabolomics, nutrigenomics, and precision medicine applications. A final section presents in-depth analytical methods for tracking these various biosystems, including high-throughput technologies, deep learning, machine learning, bioinformatics models, and spectroscopic and sensor-based techniques.

  • Cytokine-Based immunotherapy Part B

    • 1st Edition
    • Volume 401
    • June 1, 2026
    • English
    Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From their fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1st Edition
    • June 1, 2026
    • Vahid Mansouri + 1 more
    • English
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 88
    • June 1, 2026
    • English
    Advances in Microbial Physiology explores the latest research and developments in the field of microbial physiology, providing a comprehensive overview of how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi.

  • Stem Cell-Mediated Regulation of Pyroptosis

    • 1st Edition
    • May 15, 2026
    • Debalina Bhattacharya + 1 more
    • English
    Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells before delving into the interaction across various conditions, ranging from cerebral injury, spinal injury, cardiac injury, osteoarthritis, cancer, and more. Users will find the latest research and future directions in the study of stem cells and pyroptosis, thus enabling further understanding of the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. Therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions are also considered, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics, and other related fields.

  • Chromatin Signaling and Diseases

    • 2nd Edition
    • May 1, 2026
    • Olivier Binda + 2 more
    • English
    Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.

  • Molecular Mechanisms of Spermatogenesis

    • 1st Edition
    • Volume 168
    • May 1, 2026
    • English
    Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.

  • Fundamentals of Molecular Structural Biology

    • 2nd Edition
    • May 1, 2026
    • Subrata Pal
    • English
    Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

  • Cell Death Part B

    • 1st Edition
    • Volume 206
    • May 1, 2026
    • English
    Cell Death Part B continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deeper into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

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