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Elsevier

Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Molecular Biology and Pathology

    A Guidebook for Quality Control
    • 1st Edition
    • Daniel H. Farkas
    • English
    This is the first handbook to provide an all-in-one guide to establishing molecular biology protocols with requisite quality control. Molecular Biology and Pathology will help professionals sift through the incredible wealth of information available on molecular biology, specifically as it relates to the clinical arena of molecular pathology. This handbook provides excellent training information, and the concern of safety is discussed extensively. The handbook can serve as a primer and reference for those interested in the technical topics described, including the brief discussion of DNA banking. Quality Control (QC) suggestions are also presented.

  • Molecular Biology

    Elementary Processes of Nerve Conduction and Muscle Contraction
    • 1st Edition
    • David Nachmansohn
    • English
    Molecular Biology: Elementary Processes of Nerve Conduction and Muscle Contraction focuses on the underlying elementary processes of muscular contraction and nerve impulse conduction. This book explores the fundamental concepts and notions in molecular biology. Organized into 11 chapters, this book starts with an overview of the double array model of striated muscle. This text then discusses the structural changes at the molecular level, which occur as a consequence or an accompaniment of the chemical reactions that occur during contraction. Other chapters explain the process by which molecular changes are summated to produce macroscopic shortenings. This book discusses as well the molecular complementarity and chemistry of acetylcholinesterase... which provides significant information for the understanding of nervous activity. The final chapter deals with the structure of guanidinium ion, which consists of three equivalent NH2 groups arranged with a planar trigonal symmetry around the central carbon atom. Physicists, chemists, and biologists will find this book useful.

  • Cellular Membranes in Development

    • 1st Edition
    • Michael Locke
    • English
    Cellular Membranes in Development covers the proceedings of the 1963 22nd Symposium on ""The Society for the Study of Development and Growth"" held in Storrs, Connecticut. This book is organized into 10 chapters that discuss the properties, isolation, function, composition, and physiological aspects of membranes. After briefly dealing with the principles of the unit membrane concept, the book describes the properties of lipid membranes of bilayer thickness with biological relevance. The next chapter focuses on hepatic cell and the modifications of the endoplasmic reticulum in cell differentiation in normal and cancerous growth. Another chapter describes the developmental changes in a particular experimental systems and the modification of the membranes by specific treatments using the apical portion of the primary root of Zea mays. The book also discusses the role of the different organelles in development, supporting the idea of topological continuity between the membranes of all the organelles except the mitochondria. Other chapters describe the cytology of oogenesis and fertilization in Pteridium aquilinum; the early events of fertilization in Hydroides and Saccoglossus; and the composition of cell walls of bacteria, yeast, and fungi. Some aspects of the capsules, microcapsules, and sheaths exhibited by some microorganisms are also covered. The last chapters deal with the quantitative aspects of plant cell permeation and permeability function and changes in relation to maturation and growth hormones. The book is an ideal source for cell biologists and researchers, evolutionists, and biochemists.

  • The Cell in Mitosis

    • 1st Edition
    • Laurence Levine
    • English
    The Cell in Mitosis is a collection of papers presented at the First Annual Symposium held on November 6-8, 1961 under the provisions of The Wayne State Fund Research Recognition Award. Contributors focus on the complexities posed by the cell in division and consider topics such as the chemical prerequisites for cell division, the role of the centriole in division cycles, development of the cleavage furrow, chemical aspects of the isolated mitotic apparatus, histone variability, and actin polymerization. This volume is organized into 11 chapters and begins with an overview of cell division, with reference to the basic essential mechanisms of mitogeneses underlying the emergence of the elegant geometries of mitosis. An account of the congression of chromosomes onto metaphase configuration and progression through telophase is also given. The next chapters explore the identity and role of the centriole in the whole life cycle of cell behavior; the fine structure of animal cells during cytokinesis; the mechanism of saltatory particle movements during mitosis; and how chemical and physical agents disrupt the mitotic cycle. A chapter is devoted to the holotrichous ciliate, Tetrahymena pyriformis, paying attention to its fine structure during mitosis. This book will be of interest to physiologists, electron microscopists, light microscopists, biochemists, and others who want to know more about the various aspects of cell division.

  • RNA: Catalysis, Splicing, Evolution

    • 1st Edition
    • M. Belfort + 1 more
    • English
    The conference on "RNA: Catalysis, Splicing, Evolution" brought together a unique assembly of scientific leaders in this currently very important field. Two participants of this Conference, Drs. T.R. Cech and S. Altman, were just awarded the 1989 Nobel prize in chemistry, which attests to the timeliness of this volume. The critical reviews authored by these two prominent scientists are included. For those scientists with roots in this field, who do not subscribe to GENE, this is an excellent opportunity to obtain a masterly collection of papers. All the original papers and reviews have undergone the rigorous peer review of the journal "Gene".

  • Flow Cytogenetics

    • 1st Edition
    • Johan S. Ploem
    • English
    This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source.

  • The Initiation of DNA Replication

    • 1st Edition
    • Dan S Ray
    • English
    The Initiation of DNA Replication contains the proceedings of the 1981 ICN-UCLA Symposia on Structure and DNA-Protein Interactions of Replication Origins, held in Salt Lake City, Utah on March 8-13, 1981. The papers explore the initiation of DNA replication and address relevant topics such as whether there are specific protein recognition sites within an origin; how many proteins interact at an origin and whether they interact in a specific temporal sequence; or whether origins can be subdivided into distinct functional domains. The specific biochemical steps in DNA chain initiation and how they are catalyzed are also discussed. This book is organized into six sections and comprised of 41 chapters. The discussion begins by analyzing the replication origin region of the Escherichia coli chromosome and the precise location of the region carrying autonomous replicating function. A genetic map of the replication and incompatibility regions of the resistance plasmids R100 and R1 is described, and several gene products produced in vivo or in vitro from the replication region are considered. The sections that follow focus on the DNA initiation determinants of bacteriophage M13 and of chimeric derivatives carrying foreign replication determinants; suppressor loci in E. coli; and enzymes and proteins involved in initiation of phage and bacterial chromosomes. The final chapters examine the origins of eukaryotic replication. This book will be of interest to scientists, students, and researchers in fields ranging from microbiology and molecular biology to biochemistry, molecular genetics, and physiology.

  • Heredity

    • 1st Edition
    • I Gunsalus
    • English
    The Bacteria: A Treatise on Structure and Function, Volume V: Heredity explores the role of bacterial genetics in heredity. The book includes chapters on genetic fine structure, genetic replication, and gene-enzyme relationships, along with gene transduction, bacterial episomes, and genetic recombination. This volume is organized into 10 chapters and begins with an overview of conjugation as a mechanism of genetic exchange in bacterial species such as Escherichia coli, Salmonella typhosa, Pseudomonas aeruginosa, Vibrio cholera, and Serratia marcescens. The book then discusses transduction, its uses and evolutionary implications, and the nature of the transducing particle as well as the transduction of galactose genes by bacteriophage lambda. The reader is also introduced to transformation and its use in genetic analysis, along with bacterial episomes and genetic transfer; genetic recombination and other genetic phenomena in streptomycetes; and DNA replication. The book concludes by explaining how bacteria should be defined from a biological standpoint. This book is a valuable source of information for geneticists, biochemists, biologists, and research workers involved in the biological sciences.

  • Physical Forces and the Mammalian Cell

    • 1st Edition
    • Bozzano G Luisa
    • English
    This book examines the physical forces - fluid shear, stretch, and gravity that play a role in the physiology of tissues and cellular functions. It gives special attention to the influences of the flow of blood and exercise on the growth of blood vessels and the flow of interstitial fluid on bone formation. Pathological conditions are also presented, such as the lack of mechanical loading on bone and osteoporosis. For biotechnologists, the problem of cell susceptibility to agitation-induced hydrodynamic forces in the scale-up of mammalian cell bioreactors is examined.

  • Molecular Biology of the Fission Yeast

    • 1st Edition
    • English
    This highly researched yeast, which represents a system used by cell biologists, geneticists and molecular biologists, has been given only minimal coverage in the literature. Its properties make it an excellent organism for DNA and related biotechnology reseach. This book, which is the first attempt to collate existing information in one source, will be an invaluable aid to those initiating projects with this organism.

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