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Elsevier

Academic Press

  • Agglutination, Complement, Neutralization, and Inhibition

    Methods in Immunology and Immunochemistry, Vol. 4
    • 1st Edition
    • Curtis A. Williams + 1 more
    • English
    Methods in Immunology and Immunochemistry, Volume IV: Agglutination, Complement, Neutralization, and Inhibition provides information pertinent to direct and indirect agglutination reactions. This book covers a variety of topics, including complement-fixation procedures, isolation of complement components, hemolytic intermediates, complement-related proteins, and neutralization reactions. Organized into three chapters, this volume begins with an overview of test-tube agglutinations that are preferred for blood grouping with saline agglutinins that require more than a few minutes for agglutination. This text then describes blood group antibodies that agglutinate red blood cells suspended in saline. Other chapters consider the classical pathway of complement utilization. This book discusses as well the complexity of events leading to hemolysis of erythrocytes by complement. The final chapter deals with the ability of antitoxin to neutralize diphtheria toxin and explains the quantitative relationships between antigen and antibody. This book is a valuable resource for immunologists, scientists, and research workers.

  • Nonlinear Differential Equations

    Invariance, Stability, and Bifurcation
    • 1st Edition
    • Piero de Mottoni + 1 more
    • English
    Nonlinear Differential Equations: Invariance, Stability, and Bifurcation presents the developments in the qualitative theory of nonlinear differential equations. This book discusses the exchange of mathematical ideas in stability and bifurcation theory. Organized into 26 chapters, this book begins with an overview of the initial value problem for a nonlinear wave equation. This text then focuses on the interplay between stability exchange for a stationary solution and the appearance of bifurcating periodic orbits. Other chapters consider the development of methods for ascertaining stability and boundedness and explore the development of bifurcation and stability analysis in nonlinear models of applied sciences. This book discusses as well nonlinear hyperbolic equations in further contributions, featuring stability properties of periodic and almost periodic solutions. The reader is also introduced to the stability problem of the equilibrium of a chemical network. The final chapter deals with suitable spaces for studying functional equations. This book is a valuable resource for mathematicians.

  • Identification, Equivalent Models, and Computer Algebra

    Statistical Modeling and Decision Science
    • 1st Edition
    • Paul A. Bekker + 2 more
    • Gerald J. Lieberman + 1 more
    • English
    Identification, Equivalent Models, and Computer Algebra provides information pertinent to computer algebra. This book presents a brief discussion of the commutation matrix, an operator that plays a role when derivatives have to be evaluated involving symmetric matrices. Organized into eight chapters, this book begins with an overview of the link between identification of a parameter and the existence of a consistent estimator, and the link between identification of a model and the rank of a Jacobian matrix. This text then describes an algorithm for the determination of the exact rank of a parametrized matrix. Other chapters consider the identification in the simultaneous equation model. This book discusses as well the identification assessment in confirmatory factor analysis, a problem related to the simultaneous equations model. The final chapter deals with various computer programs that the enclosed diskette contains. This book is a valuable resource for readers who are interested in computer algebra.

  • The Antigens

    Volume II
    • 1st Edition
    • Michael Sela
    • English
    The Antigens, Volume II is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from protein antigens and blood group antigens to low molecular weight antigens and immunoglobulin A. The idiotypy of antibodies is also explored, along with the application of antibodies to the measurement of substances of physiological and pharmacological interest. Comprised of six chapters, this volume begins with a discussion on the molecular bases of antigenicity and immunogenicity of proteins, followed by a chapter dealing with blood group antigens. The immunologic effects of low molecular weight antigens are then considered, together with their elicitation of allergic reactions and their tolerance and specific inhibition of the immune response. The next chapter focuses on the use of antibodies to measure substances of physiological and pharmacological interest, with emphasis on the general principle of quantitative immunoassay. The book also analyzes the idiotypy of antibodies before concluding with a description of the antibody functions of immunoglobulin A. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

  • Disorders of Mineral Metabolism

    Calcium Physiology
    • 1st Edition
    • Jack W. Coburn + 1 more
    • English
    Disorders of Mineral Metabolism, Volume II: Calcium Physiology is a nine-chapter text that deals with the normal function of calcium, with much emphasis on a host of intracellular functions. This volume discusses the calcium absorption, excretion, and homeostasis, as well as the hormonal modifiers of its metabolism. The role of connective tissue and bone, the major storehouse of body calcium, is reviewed in terms of collagen metabolism. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.

  • Associative Networks

    Representation and Use of Knowledge by Computers
    • 1st Edition
    • Nicholas V. Findler
    • English
    Associative Networks: Representation and Use of Knowledge by Computers is a collection of papers that deals with knowledge base of programs exhibiting some operational aspects of understanding. One paper reviews network formalism that utilizes unobstructed semantics, independent of the domain to which it is applied, that is also capable of handling significant epistemological relationships of concept structuring, attribute/value inheritance, multiple descriptions. Another paper explains network notations that encode taxonomic information; general statements involving quantification; information about processes and procedures; the delineation of local contexts, as well as the relationships between syntactic units and their interpretations. One paper shows that networks can be designed to be intuitively and formally interpretable. Network formalisms are computer-oriented logics which become distinctly significant when access paths from concepts to propositions are built into them. One feature of a topical network organization is its potential for learning. If one topic is too large, it could be broken down where groupings of propositions under the split topics are then based on "co-usage" statistics. As an example, one paper cites the University of Maryland artificial intelligence (AI) group which investigates the control and interaction of a meaning-based parser. The group also analyzes the inferences and predictions from a number of levels based on mundane inferences of actions and causes that can be used in AI. The collection can be useful for computer engineers, computer programmers, mathematicians, and researchers who are working on artificial intelligence.

  • Symbolic Play

    The Development of Social Understanding
    • 1st Edition
    • Inge Bretherton
    • English
    Symbolic Play: The Development of Social Understanding describes the development of symbolic play from infancy through the preschool years. This text is divided into 12 chapters that focus on make-believe as an activity within which young children spontaneously represent and practice their understanding of the social world. The first chapter introduces the development of event schemata produced in symbolic play, about children's management of the playframe, and about the development of subjunctive, or "what if" thought. The next chapters are devoted to the development of joint pretending, specifically the use if shared scripts in the organization of make-believe play and the subtleties of metacommunication. These chapters also emphasize the supporting role of the mother in early collaborative make-believe. These topics are followed by discussions of the child's growing ability to represent the internal states of the inanimate figures whose doing can vicariously enacts. The remaining chapters focus on social interaction through symbolic play with dolls, toy animals, object props, and language. This book will prove useful to psychologists and researchers in the fields of human development, society, and family.

  • The Cell Surface: Mediator of Developmental Processes

    • 1st Edition
    • Stephen Subtelny + 1 more
    • English
    The Cell Surface: Mediator of Developmental Processes contains the papers presented at the 38th Symposium of the Society for Developmental Biology, held at the University of British Columbia in Vancouver, Canada in June 1979. The compendium is divided into three parts. The first part provides a summary of the status of the knowledge about the cell surface, which includes the plasma membrane, its associated cytoskeleton and the variety of surface-associated macromolecules. The second portion focuses on the early development of the cell surface. A wide spectrum of techniques, systems, and results in the study of the cell surface are presented. The last part shows a variety of experimental systems in which the cell surface figures prominently in important developmental events. The results from experiments on plant symbiosis, mammalian teratocarcinomas, adhesion and cell shape, and various extracellular macromolecules are detailed extensively. Cytologists, microbiologists, biologists, and other scientists in allied fields will find the publication very insightful.

  • Teaching of Statistics and Statistical Consulting

    • 1st Edition
    • Jagdish S. Rustagi + 1 more
    • English
    Teaching of Statistics and Statistical Consulting is a collection of papers dealing with graduate programs in statistics; teaching service courses and short courses; and training statisticians for employment in industry and government. Some papers also deal with the role of statistical consulting in graduate training and teaching statistics at the Open University. One paper describes some observations made on graduate program in statistics, citing concerns of professionalism, competency, and a highly structured university curriculum. Another paper takes a task analysis approach to designing a regression analysis course where, with proper course structuring, students will actively learn to do the objectives of the course. Other papers discuss consulting and research work at the Australian Government's research organization, as well as how to prepare statisticians for future government service or for the private industry. One paper deals with some important things that a practicing statistician should know, but which are seldom taught in statistics courses. Another paper describes teaching statistics at a distance from the Open University in the United Kingdom. The collection can prove helpful for academic statisticians in educational institutions, to statisticians, or to mathematicians employed in the public or private sectors.

  • Special Purpose Computers

    • 1st Edition
    • Berni J. Alder
    • English
    Special Purpose Computers describes special-purpose computers and compares them to general-purpose computers in terms of speed and cost. Examples of computers that were designed for the efficient solution of long established algorithms are given, including Navier-Stokes hydrodynamic solvers, classical molecular dynamic machines, and Ising model computers. Comprised of seven chapters, this volume begins by documenting the progress of the CalTech Concurrent Computation Program and its evolution from computational high-energy physics to a supercomputer initiative, with emphasis on the lessons learned including computer architecture issues and the trade-offs between in-house and commercial development. The reader is then introduced to the QCD Machine, a special-purpose parallel supercomputer that was designed and built to solve the lattice quantum chromodynamics problem. Subsequent chapters focus on the Geometry-Defining Processors and their application to the solution of partial differential equations; the Navier-Stokes computer; parallel processing using the Loosely Coupled Array of Processors (LCAP) system; and the Delft Ising system processor. The design and implementation of the Delft molecular-dynamics processor are also described. This book will be of interest to computer engineers and designers.

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