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  • Animal Biotechnology

    Models in Discovery and Translation
    • 2nd Edition
    • Ashish S. Verma + 1 more
    • English
    Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more.

  • Human-Machine Shared Contexts

    • 1st Edition
    • William Lawless + 2 more
    • English
    Human-Machine Shared Contexts considers the foundations, metrics, and applications of human-machine systems. Editors and authors debate whether machines, humans, and systems should speak only to each other, only to humans, or to both and how. The book establishes the meaning and operation of “shared contexts” between humans and machines; it also explores how human-machine systems affect targeted audiences (researchers, machines, robots, users) and society, as well as future ecosystems composed of humans and machines. This book explores how user interventions may improve the context for autonomous machines operating in unfamiliar environments or when experiencing unanticipated events; how autonomous machines can be taught to explain contexts by reasoning, inferences, or causality, and decisions to humans relying on intuition; and for mutual context, how these machines may interdependently affect human awareness, teams and society, and how these "machines" may be affected in turn. In short, can context be mutually constructed and shared between machines and humans? The editors are interested in whether shared context follows when machines begin to think, or, like humans, develop subjective states that allow them to monitor and report on their interpretations of reality, forcing scientists to rethink the general model of human social behavior. If dependence on machine learning continues or grows, the public will also be interested in what happens to context shared by users, teams of humans and machines, or society when these machines malfunction. As scientists and engineers "think through this change in human terms," the ultimate goal is for AI to advance the performance of autonomous machines and teams of humans and machines for the betterment of society wherever these machines interact with humans or other machines. This book will be essential reading for professional, industrial, and military computer scientists and engineers; machine learning (ML) and artificial intelligence (AI) scientists and engineers, especially those engaged in research on autonomy, computational context, and human-machine shared contexts; advanced robotics scientists and engineers; scientists working with or interested in data issues for autonomous systems such as with the use of scarce data for training and operations with and without user interventions; social psychologists, scientists and physical research scientists pursuing models of shared context; modelers of the internet of things (IOT); systems of systems scientists and engineers and economists; scientists and engineers working with agent-based models (ABMs); policy specialists concerned with the impact of AI and ML on society and civilization; network scientists and engineers; applied mathematicians (e.g., holon theory, information theory); computational linguists; and blockchain scientists and engineers.

  • Transdermal Drug Delivery

    Concepts and Application
    • 1st Edition
    • Kevin Ita
    • English
    Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful.

  • Phenotypic Switching

    Implications in Biology and Medicine
    • 1st Edition
    • Herbert Levine + 3 more
    • English
    Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast.

  • Contemporary Practice in Clinical Chemistry

    • 4th Edition
    • William Clarke + 1 more
    • English
    Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry.

  • Practical Machine Learning for Data Analysis Using Python

    • 1st Edition
    • Abdulhamit Subasi
    • English
    Practical Machine Learning for Data Analysis Using Python is a problem solver’s guide for creating real-world intelligent systems. It provides a comprehensive approach with concepts, practices, hands-on examples, and sample code. The book teaches readers the vital skills required to understand and solve different problems with machine learning. It teaches machine learning techniques necessary to become a successful practitioner, through the presentation of real-world case studies in Python machine learning ecosystems. The book also focuses on building a foundation of machine learning knowledge to solve different real-world case studies across various fields, including biomedical signal analysis, healthcare, security, economics, and finance. Moreover, it covers a wide range of machine learning models, including regression, classification, and forecasting. The goal of the book is to help a broad range of readers, including IT professionals, analysts, developers, data scientists, engineers, and graduate students, to solve their own real-world problems.

  • TARP and other Bank Bailouts and Bail-Ins around the World

    Connecting Wall Street, Main Street, and the Financial System
    • 1st Edition
    • Allen N. Berger + 1 more
    • English
    Financial crises are recurring phenomena that result in the financial distress of systemically important banks, making it imperative to understand how to best respond to such crises and their consequences. Two policy responses became prominent for dealing with these distressed institutions since the last Global Financial Crisis: bailouts and bail-ins. The main questions surrounding these responses touch everyone: Are bailouts or bail-ins good for the financial system and the real economy? Is it essential to save distressed financial institutions by putting taxpayer money at risk in bailouts, or is it better to use private money in bail-ins instead? Are there better options, such as first lines of defense that help prevent such distress in the first place? Can countercyclical prudential and monetary policies lessen the likelihood and severity of the financial crises that often bring about this distress? Through careful analysis, authors Berger and Roman review and critically assess the extant theoretical and empirical research on many resolution approaches and tools. Placing special emphasis on lessons learned from one of the biggest bailouts of all time, the Troubled Asset Relief Program (TARP), while also reviewing other programs and tools, TARP and Other Bank Bailouts and Bail-Ins around the World sheds light on how best to protect the financial system on Wall Street and the real economy on Main Street.

  • Segregation in Vibrated Granular Systems

    • 1st Edition
    • Anthony D. Rosato + 1 more
    • English
    Segregation in Vibrated Granular Systems explains the individual mechanisms that influence the segregation of granular media under vibration, along with their interactions. Drawing on research from a wide range of academic disciplines, the book focuses on vibrated granular systems that are used in industry, providing a guide that will solve practical problems and help researchers. The applications of vibration-based segregation in industries, including pharmaceuticals, mining, food and chemical processing are all investigated with appropriate examples. In addition, relevant theory behind the behavior of granular media and segregation processes is explained, along with investigations of the technologies and techniques used.

  • Three Facets of Public Health and Paths to Improvements

    Behavior, Culture, and Environment
    • 1st Edition
    • Beth Ann Fiedler
    • English
    Three Facets of Public Health and Paths to Improvements provides an overview on how specific indicators like the environment, culture and behavior play a role in developing improved outcomes for public health in local, regional, national and global health policy and concerns. Divided into three sections, the book examines the impact of the environment and social determinants on public health. It also illustrates the interrelation of these facets as predictors of public health, explores their institutional, organizational and individual impacts, and considers the way multiple stakeholders must engage to improve conditions that impact health. The book utilizes various research methods, including fundamental, systematics, qualitative and quantitative. Readers can use the information to inform future research and better understand an existing health problem and outcomes.

  • Past Antarctica

    Paleoclimatology and Climate Change
    • 1st Edition
    • Marc Oliva + 1 more
    • English
    Past Antarctica: Paleoclimatology and Climate Change presents research on the past and present of Antarctica in reference to its current condition, including considerations for effects due to climate change. Experts in the field explore key topics, including environmental changes, human colonization and present environmental trends. Addressing a wide range of fields, including the biosphere, geology and biochemistry, the book offers geographers, climatologists and other Earth scientists a vital resource that is beneficial to an understanding of Antarctica, its history and conservation efforts.

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