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Academic Press

  • Ethical Considerations When Preparing a Clinical Research Protocol

    • 2nd Edition
    • Evan DeRenzo + 2 more
    • English
    Ethical Considerations When Preparing a Clinical Research Protocol, Second Edition, provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, how to design appropriate research studies, how to consent and assent documents, how to get protocols approved, special populations, confidentiality issues, and the reporting of adverse events. The book's valuable appendix includes a listing of web resources about research ethics, along with a glossary, making it an invaluable resource for scientists collaborating in clinical trials, physician investigators, clinical research fellows, and more.

  • Oxidative Stress and Dietary Antioxidants in Neurological Diseases

    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Oxidative Stress and Dietary Antioxidants in Neurological Diseases provides an overview of oxidative stress in neurological diseases and associated conditions, including behavioral aspects and the potentially therapeutic usage of natural antioxidants in the diet. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. The book examines basic processes of oxidative stress—from molecular biology to whole organs—relative to cellular defense systems, and across a range of neurological diseases. Sections discuss antioxidants in foods, including plants and components of the diet, examining the underlying mechanisms associated with therapeutic potential and clinical applications. Although some of this material is exploratory or preclinical, it can provide the framework for further in-depth analysis or studies via well-designed clinical trials or the analysis of pathways, mechanisms, and components in order to devise new therapeutic strategies. Very often oxidative stress is a feature of neurological disease and associated conditions which either centers on or around molecular and cellular processes. Oxidative stress can also arise due to nutritional imbalance during a spectrum of timeframes before the onset of disease or during its development.

  • Lattice Boltzmann Modeling for Chemical Engineering

    • 1st Edition
    • Volume 55
    • English
    Lattice Boltzmann Modeling for Chemical Engineering, Volume 56 in the Advances in Chemical Engineering series, highlights new advances in the field, with this new volume presenting interesting chapters on Simulations of homogeneous and heterogeneous chemical reactions, LBM for 3D Chemical Reactors, LBM Simulations of PEM fuel cells, LBM for separation processes, LBM for two-phase flow (bio)reactors, and more.

  • Mental and Behavioral Health of Immigrants in the United States

    Cultural, Environmental, and Structural Factors
    • 1st Edition
    • Gordon C. Nagayama Hall
    • English
    Mental and Behavioral Health of Immigrants in the United States reviews research on immigrant mental health, acculturation, and multicultural psychology. The book is divided into three sections: Section A addresses the geographic and social context of immigration, including how parents and children navigate the acculturation process, how different cultural orientations affect behavior, and research methods on acculturation. Sections B and C focus on mental health issues common to Latinx, Asian, and Arab/Middle Eastern immigrants, and then more broadly across immigrant groups. Included here are a focus on depression, anxiety, and somatization, as well as alcohol abuse, insomnia, and issues for LGBTQ+ individuals. Pre- and post-migration stressors are discussed, as well as the effects of prejudice and bias, the mental health effects of religion and spirituality, and managing the demands of both work and family. Contributors from psychology, education, and social work provide different perspectives and identify opportunities for future research.

  • Jaguars of the Northern Pantanal

    Panthera Onca at the Meeting of the Waters
    • 1st Edition
    • Paul Brooke + 1 more
    • English
    Jaguars of the Northern Pantanal: Panthera Onca at the Meeting of the Waters details the lives and behaviors of this subpopulation of jaguars through one-of-a-kind photographs from 26 international photographers, as well as illustrations, maps, waypoints, scientific insights, field journal excerpts and personal narratives. The book seeks to understand how locals can coexist with these cats while benefitting financially through ecotourism. Users will find this book to be a conceptual model to apply to other subpopulations in order to save jaguars throughout North and South America. It is an ideal resource for researchers and practitioners in wildlife conservation, naturalism ecotourism and biologists.

  • Toxicological Aspects of Medical Device Implants

    • 1st Edition
    • Prakash Srinivasan Timiri Shanmugam + 2 more
    • English
    Toxicological Aspects of Medical Device Implants provides comprehensive information on the use of medical implant and devices and the balance between the application of the devices in relation to any potential adverse effects. In order to ensure the safety and effectiveness of medical devices, many international policies, regulations, and standards have been established, and the book also discusses medical devices within this regulatory framework. The book covers a broad range of disease topics and disease-specific implants and an interdisciplinary team of experts brings a wealth of information on implants used in various disease models and associated risk factors. Toxicological Aspects of Medical Device Implants is a comprehensive resource for toxicologists, biomedical engineers, immunologists, medical staff, regulators, and manufacturers working in the field who need to be aware of the potential toxicity and device management of such a wide variety of implants and devices and their health risks.

  • Neural Circuit and Cognitive Development

    Comprehensive Developmental Neuroscience
    • 2nd Edition
    • John Rubenstein + 3 more
    • English
    Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop.

  • Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles

    • 1st Edition
    • Peter Gill + 4 more
    • English
    Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner’s Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience

  • Nanotechnology Based Approaches for Tuberculosis Treatment

    • 1st Edition
    • Prashant Kesharwani
    • English
    Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis.

  • Goodman's Medical Cell Biology

    • 4th Edition
    • Steven R. Goodman
    • English
    Goodman’s Medical Cell Biology, Fourth Edition, has been student tested and approved for decades. This updated edition of this essential textbook provides a concise focus on eukaryotic cell biology (with a discussion of the microbiome) as it relates to human and animal disease. This is accomplished by explaining general cell biology principles in the context of organ systems and disease.This new edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.

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