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Elsevier

Academic Press

  • In Situ Molecular Pathology and Co-expression Analyses

    • 2nd Edition
    • Gerard J. Nuovo
    • English
    Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry...

  • Nano Drug Delivery Strategies for the Treatment of Cancers

    • 1st Edition
    • Awesh K. Yadav + 2 more
    • English
    Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.

  • pH-Interfering Agents as Chemosensitizers in Cancer Therapy

    • 1st Edition
    • Volume 10
    • Claudiu T. Supuran + 1 more
    • English
    pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered.

  • Enzyme Engineering and Evolution: General Methods

    • 1st Edition
    • Volume 643
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Measurement and Instrumentation

    Theory and Application
    • 3rd Edition
    • Alan S. Morris + 1 more
    • English
    Measurement and Instrumentation: Theory and Application, Third Edition, introduces undergraduate engineering students to measurement principles and the range of sensors and instruments used for measuring physical variables. Providing the most balanced coverage of measurement theory/technologies and instrumentation, this clearly and comprehensively written text arms students and recently graduated engineers with the knowledge and tools to design and build measurement systems for virtually any engineering application.

  • Morphological Image Operators

    • 1st Edition
    • Volume 216
    • English
    Advances in Imaging and Electron Physics, Volume 216, merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. The series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy and the computing methods used in all these domains.

  • Plant Cell Biology

    • 1st Edition
    • Volume 160
    • English
    Plant Cell Biology, volume 160 in "Methods in Cell Biology", includes chapters on modern experimental procedures and applications developed for research in the broad area of plant cell biology. Topics covered in this volume include techniques for imaging and analyzing membrane dynamics and movement across membranes; cell wall composition, structure and mechanics; cytoskeleton dynamics and organization; cell development; ion channel physiology; cell mechanics; and methods related to quantifying cell morphogenesis.

  • Microbiomes and Plant Health

    Panoply and Their Applications
    • 1st Edition
    • Manoj Kumar Solanki + 3 more
    • English
    Microbiomes and Plant Health: Panoply and Their Applications includes the most recent advances in phytobiome research. The book emphasizes the use of modern molecular tools such as smart delivery systems for microbiol inoculation, next-generation sequencing, and genome mapping. Chapters discuss a variety of applications and examples, including the sugarcane microbiome, rhizoengineering, nutrient recycling, sustainable agricultural practices and bio-potential of herbal medicinal plants. Written by a range of experts with real-world practical insights, this title is sure to be an essential read for plant and soil microbiologists, phytopathologists, agronomists, and researchers interested in sustainable forestry and agriculture practices.

  • Intelligent Data Security Solutions for e-Health Applications

    • 1st Edition
    • Amit Kumar Singh + 1 more
    • English
    E-health applications such as tele-medicine, tele-radiology, tele-ophthalmology, and tele-diagnosis are very promising and have immense potential to improve global healthcare. They can improve access, equity, and quality through the connection of healthcare facilities and healthcare professionals, diminishing geographical and physical barriers. One critical issue, however, is related to the security of data transmission and access to the technologies of medical information. Currently, medical-related identity theft costs billions of dollars each year and altered medical information can put a person’s health at risk through misdiagnosis, delayed treatment or incorrect prescriptions. Yet, the use of hand-held devices for storing, accessing, and transmitting medical information is outpacing the privacy and security protections on those devices. Researchers are starting to develop some imperceptible marks to ensure the tamper-proofing, cost effective, and guaranteed originality of the medical records. However, the robustness, security and efficient image archiving and retrieval of medical data information against these cyberattacks is a challenging area for researchers in the field of e-health applications. Intelligent Data Security Solutions for e-Health Applications focuses on cutting-edge academic and industry-related research in this field, with particular emphasis on interdisciplinary approaches and novel techniques to provide security solutions for smart applications. The book provides an overview of cutting-edge security techniques and ideas to help graduate students, researchers, as well as IT professionals who want to understand the opportunities and challenges of using emerging techniques and algorithms for designing and developing more secure systems and methods for e-health applications.

  • Fundamentals of Optimization Techniques with Algorithms

    • 1st Edition
    • Sukanta Nayak
    • English
    Optimization is a key concept in mathematics, computer science, and operations research, and is essential to the modeling of any system, playing an integral role in computer-aided design. Fundamentals of Optimization Techniques with Algorithms presents a complete package of various traditional and advanced optimization techniques along with a variety of example problems, algorithms and MATLAB© code optimization techniques, for linear and nonlinear single variable and multivariable models, as well as multi-objective and advanced optimization techniques. It presents both theoretical and numerical perspectives in a clear and approachable way. In order to help the reader apply optimization techniques in practice, the book details program codes and computer-aided designs in relation to real-world problems. Ten chapters cover, an introduction to optimization; linear programming; single variable nonlinear optimization; multivariable unconstrained nonlinear optimization; multivariable constrained nonlinear optimization; geometric programming; dynamic programming; integer programming; multi-objective optimization; and nature-inspired optimization. This book provides accessible coverage of optimization techniques, and helps the reader to apply them in practice.

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