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Elsevier

Academic Press

  • Microbial Crosstalk with Immune System

    New Insights in Therapeutics
    • 1st Edition
    • Asmita Das
    • English
    Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

  • Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

    • 1st Edition
    • Sunny Ohia + 1 more
    • English
    Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-adminis... drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.

  • Essentials of Medical Biochemistry

    With Clinical Cases
    • 3rd Edition
    • Chung Eun Ha + 1 more
    • English
    Essentials of Medical Biochemistry, Third Edition offers a condensed, yet detailed overview of clinical biochemistry, spanning fundamentals and relevant physiologic and pathophysiologic concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find fundamental concepts aiding students and professionals in biochemistry, medicine, and other healthcare disciplines. The text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. This Third Edition has been fully updated to address evolving techniques in the biological sciences, including genomics, metabolomics, transcriptomics, epigenomics, proteomics, and gene therapy, among other methods. In addition, each chapter has been fully revised for current science and now features learning objectives and chapter summaries, supplemental reading, and 5 clinical case based multiple choice questions. New clinical cases have been added throughout.

  • Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management

    • 1st Edition
    • Azamal Husen
    • English
    Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management highlights the latest advances in applying this important technology within agriculture sectors for sustainable growth, production and protection. The book explores various smart engineered nanomaterials which are now being used as an important tool for improving growth and productivity of crops facing abiotic stresses, improving the health of the soil in which those crops are growing, and addressing stresses once the plant begins to produce food yield. The book includes insights into the use of nanoparticles as bactericides, fungicides and nanofertilizers. In addition, the book includes an international representation of authors who have crafted chapters with clarity, reviewing up-to-date literature with lucid illustrations. It will be an important resource for researchers, nanobiotechnologists... agriculturists and horticulturists who need a comprehensive reference guide.

  • Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology

    • 1st Edition
    • Volume 671
    • English
    Carotenoids: Carotenoid and Apocarotenoid Biosynthesis, Metabolic Engineering and Synthetic Biology, Volume 671, the latest release in the Methods of Enzymology series highlights new advances in the field with chapters on Metabolomics-based analysis of carotenoids and related metabolites in various species via quantitative trait loci and genome wide association mapping approaches, Using bacteria for functional analysis of genes encoding carotenoid biosynthetic enzymes, Rice Callus as a High Throughput Platform for Synthetic Biology and Metabolic Engineering of Carotenoids, Transient expression in Nicotiana benthamiana: A simple platform to investigate genes encoding carotenoid biosynthesis enzymes from diverse algal lineages, and much more. Additional chapters in this new release cover Protein-protein interaction techniques to investigate post-translational regulation of carotenogenesis, The isolation of sub-chromoplast structures from tomato and capsicum fruit, Carrot protoplasts as a suitable method for protein subcellular localization, High throughput production and characterization of carotenoid enzymes for structural and functional studies, Production and structural characterization of the cytochrome P450 enzymes in carotene ring hydroxylation, and more.

  • Applications of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Up and Running with AutoCAD 2023

    2D and 3D Drawing, Design and Modeling
    • 1st Edition
    • Elliot J. Gindis + 1 more
    • English
    Up and Running with AutoCAD 2023: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instruction, examples and insightful explanations. The book emphasizes core concepts and practical applications of AutoCAD in engineering, architecture and design. Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind.

  • Sodium-cooled Fast Reactors

    • 1st Edition
    • Volume 3
    • Masaki Morishita + 1 more
    • English
    Sodium-cooled Fast Reactors is the third volume in the JSME Series on Thermal and Nuclear Power Generation, which presents a comprehensive view of the latest research and activities from around the globe. Volume Editors Masaki Morishita and Hiroyuki Ohshima, along with their team of expert contributors, combine their knowledge and experience to provide a solid understanding of the history of SFRs and work carried out in Japan to date. This book uniquely includes case studies from these global regions to highlight SFR uses, benefits and challenges, focusing on their safety, design, operation, and maintenance. Unique to this publication, the JSME cover key technological advances which will shape power generation of the future, including developments in the use of AI for design. Drawing on their unique experience, the authors pass on lessons learned and best practices to support professionals and researchers in their development and design of this advanced reactor type.

  • Cycling

    • 1st Edition
    • Volume 10
    • English
    This volume addresses key contemporary aspects in cycling policy, practice and research. Cycling has seen a sharp increase in scientific and policy attention in the past decade. The amount of research has surged over the past couple decades. Also, levels of cycling have increased substantially in many countries and cities, and many areas have seen increases in infrastructure investments. In addition, the last decade has seen innovations in bicycle technology, in particularly the rise of electric-assist (e-bikes) and dock-less bike sharing schemes. This volume reviews the state of the art on cycling from various angles. As such it explores planners’ (engineers’, policy makers’) provisions for cycling, of cyclists’ (and non-cyclists’) travel behaviour, and resulting consequences for individuals and society. One focus is on demand-side aspects, including the use of bicycles and their users including patterns and trends in cycling, determinants of cycling, and modelling of cycling. Another focus is on impacts of cycling, such as emissions, safety aspects, as well as changes during the COVID pandemic.

  • Artificial Intelligence Methods for Optimization of the Software Testing Process

    With Practical Examples and Exercises
    • 1st Edition
    • Sahar Tahvili + 1 more
    • English
    Artificial Intelligence Methods for Optimization of the Software Testing Process: With Practical Examples and Exercises presents different AI-based solutions for overcoming the uncertainty found in many initial testing problems. The concept of intelligent decision making is presented as a multi-criteria, multi-objective undertaking. The book provides guidelines on how to manage diverse types of uncertainty with intelligent decision-making that can help subject matter experts in many industries improve various processes in a more efficient way. As the number of required test cases for testing a product can be large (in industry more than 10,000 test cases are usually created). Executing all these test cases without any particular order can impact the results of the test execution, hence this book fills the need for a comprehensive resource on the topics on the how's, what's and whys. To learn more about Elsevier’s Series, Uncertainty, Computational Techniques and Decision Intelligence, please visit this link: https://www.elsevier...

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