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Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A

  • 1st Edition, Volume 184 - November 6, 2021
  • Latest edition
  • Editors: Rajesh S. Bhosale, Vijai Singh
  • Language: English

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can he… Read more

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Description

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Emitting light is a fascinating photophysical phenomenon, its different forms have brought the attention of various disciplines of natural sciences for centuries. In the modern era of scientific generation, short-lived fluorescence light and its long-lived counterpart phosphorescence light has been employed for several chemo-sensing, bio-sensing, and bioimaging applications. The aggregation induced emission (AIE) phenomenon has appeared as a wand of modern science to convert aggregation-caused quenching (ACQ) materials into AIE active materials for a wide range of biomedical applications including biosensing, bioimaging and localization of molecules for better understanding of molecular mechanisms. This volume covers a wide range of topics which are not currently available in a single volume, including ACQ & AIE concept development; intracellular pH, temperature and viscosity sensing; imaging of cell membrane, lipid droplet, lysosome, and mitochondria; biosensing and Imaging of bacteria; nucleus and nucleic acid imaging.

Key features

  • Offers a basic understanding of AIE principle, mechanism and transformation of ACQ active to AIE active materials
  • Elucidates nucleus and nucleic acid imaging applications of AIE active small molecules
  • Describes imaging of cell membrane, lipid droplet, lysosome, and mitochondria of AIE molecules

Readership

Beginner in area of organic functional materials and biomedical, but also researchers, students, scientists, clinicians, stakeholders, policy makers and practitioners and many more

Table of contents

Preface
Vijai Singh and Rajesh S. Bhosale

1. Introduction to Aggregation Induced Emission (AIE) Materials
Rajesh S. Bhosale, Suresh K. Kalangi and Vijai Singh

2. AIE Materials for sensing of intracellular pH, Temperature and Viscosity
Sheshanath V. Bhosale

3. Advances in Aggregation Induced Emission (AIE) Materials in Biosensing and Imaging of Bacteria
Suresh K. Kalangi and Mulaka Maruthi

4. Aggregation-Induced Emission Materials for Cell Membrane Imaging
Dipratn Govindrao Khandare

5. Aggregation induced emission luminogens for lipid droplet imaging
Youhong Tang

6. AIE Materials for Lysosome Imaging
Vandana Bhalla

7. AIE Materials for Mitochondria Imaging
Kiran Kharat, Madan R. Biradar and Sidhanath Vishwanath Bhosale

8. AIE Materials for Nucleus Imaging
Rajesh S. Bhosale

9. Aggregation induced emission molecules for detection of nucleic acids
Vijai Singh, Rupesh R. Maurya, Gargi Bhattacharjee, Nisarg Gohil and Khalid J. Alzahrani

Product details

  • Edition: 1
  • Latest edition
  • Volume: 184
  • Published: November 8, 2021
  • Language: English

About the editors

RB

Rajesh S. Bhosale

Dr. Rajesh S. Bhosale is an Associate Professor at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He did his PhD (2009) from University of Geneva (Switzerland) under the supervision of Prof. Stefan Matile. Thereafter, he did first post-doctoral research as SNSF postdoctoral fellow from top institutes of World i.e. MIT-Massachusetts Institute of Technology, Cambridge, USA in the group of Prof. Timothy M. Swager and second post-doctoral research as DFG postdoctoral fellow from FRIAS-Freiburg Institute for Advanced Studies, Germany in the group of Prof. Aurelio Mateo-alonso. Where he was excelled in challenging multistep chemical synthesis, electrochemical, photophysical and self-assembly properties study of small molecules, macromolecules and polymer chromophoric systems. He also served as RMIT research associate in the group of Prof. M. Lakshmi Kantam at CSIR-IICT, Hyderabad and in July 2015 he becomes a CSIR scientist pool officer. His research interests are focused on building AIE active novel molecules.
Affiliations and expertise
Associate Professor, Department of Chemistry, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, India

VS

Vijai Singh

Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.

Affiliations and expertise
Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, India

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