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Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II
- 1st Edition, Volume 161 - November 4, 2021
- Editors: Richard L Bell, Shafiqur Rahman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 2 6 0 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 2 6 1 - 9
Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II, Volume 161, in the International Review on Neurobiology serial highlights new advances, wit… Read more
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Request a sales quoteEffects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II, Volume 161, in the International Review on Neurobiology serial highlights new advances, with this volume presenting chapters on topics including Introduction to Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Peri-adolescent Exposure to (Meth)amphetamine in Animal Models, The Impact of Adolescent Nicotine Exposure on Alcohol Use During Adulthood: The Role of Neuropeptides, Cannabis Exposure During Adolescence: A uniquely Sensitive Period for Neurobiological Effects, The Stoned Age: Sex Differences in the Effects of Adolescent Cannabinoid Exposure on Prefrontal Cortex Structure and Function in Animal Models, and more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the International Review of Neurobiology serial
- Includes the latest information on the Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS
Undergraduates, graduates, academics, and researchers in the field of peri-adolescent drug use
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Peri-adolescent exposure to (meth)amphetamine in animal models
- Abstract
- 1: Introduction
- 2: Effects of (meth)amphetamines in the peri-adolescent period
- 3: Conclusions and future directions
- References
- Chapter Two: The impact of adolescent nicotine exposure on alcohol use during adulthood: The role of neuropeptides
- Abstract
- 1: Introduction
- 2: Adolescence: A vulnerable developmental period
- 3: Adolescent nicotine/alcohol exposure and alterations in neuropeptides
- 4: Conclusion
- References
- Chapter Three: Cannabis exposure during adolescence: A uniquely sensitive period for neurobiological effects
- Abstract
- 1: Introduction
- 2: Cannabinoids and the eCB system
- 3: The endogenous cannabinoid system across the life span: Adolescence as a uniquely vulnerable period
- 4: Interactions between eCBs and dopamine: Effects on late maturing systems
- 5: Adolescent THC exposure, effects on subcortical dopamine via alterations in prefrontal GABA circuits
- 6: Conclusions
- References
- Chapter Four: The stoned age: Sex differences in the effects of adolescent cannabinoid exposure on prefrontal cortex structure and function in animal models
- Abstract
- 1: Introduction
- 2: The adolescent brain is exquisitely sensitive to exogenous cannabinoids
- 3: Effects of adolescent cannabinoid exposure on prefrontal cortex (PFC)-dependent behavior
- 4: Effects of adolescent cannabinoid exposure on prefrontal cortex (PFC) structure and function
- 5: Conclusions
- References
- Chapter Five: Adolescent opioid abuse: Role of glial and neuroimmune mechanisms
- Abstract
- 1: Introduction
- 2: Glial cells and brain development
- 3: Neuroimmune response and adolescent brain development
- 4: Opioid exposure and glial activation
- 5: Opioid exposure and glial neuroimmune signaling
- 6: Glial targets, opioid abuse, and therapeutic significance
- 7: Conclusions
- References
- Chapter Six: Adolescent neuroimmune function and its interaction with alcohol
- Abstract
- 1: Introduction
- 2: Neuroimmune development and functioning during adolescence
- 3: Early adolescent sensitivity to ethanol-induced alterations in neuroimmune processes
- 4: Impact of stress and immune stimuli on adolescent neuroimmune functioning
- 5: Conclusions
- References
- Chapter Seven: Alcohol, inflammation, and blood-brain barrier function in health and disease across development
- Abstract
- 1: Introduction
- 2: Form and function of the BBB: Gatekeeper of neurovascular unit function
- 3: Alcohol effects on BBB permeability
- 4: Alterations in BBB permeability exacerbate brain pathology
- References
- Chapter Eight: Age modifies the effect of ethanol on behavior: Investigations in adolescent, adult and aged rats
- Abstract
- 1: Effect of acute ethanol administration on behavior
- 2: Effects of chronic ethanol administration and corresponding withdrawal state on behavior
- 3: Conclusion
- References
- Chapter Nine: Early life stress and susceptibility to addiction in adolescence
- Abstract
- 1: Introduction
- 2: Adolescence
- 3: Early life stress
- 4: Investigation of molecular mechanisms underlying the ELS-induced addiction susceptibility phenotype in adolescence
- 5: Conclusions
- References
- Chapter Ten: Future directions for part II: Substance use disorders in adolescence—A vision for a better future
- 1: Future directions and strategies
- 2: Additional stakeholders for a lasting change
- References
- No. of pages: 320
- Language: English
- Edition: 1
- Volume: 161
- Published: November 4, 2021
- Imprint: Academic Press
- Hardback ISBN: 9780323992602
- eBook ISBN: 9780323992619
RB
Richard L Bell
Dr. Bell received a Bachelor of Arts in General Psychology and Addiction Counseling from Minot State University (Minot, ND) and went on to receive a Master of Science and a Doctor of Philosophy in Applied Biopsychology, with a minor in Biostatistics, from the University of New Orleans (New Orleans, LA). He is presently an Associate Professor of Psychiatry at the Indiana University School of Medicine (Indianapolis, IN). He has been researching the in vivo effects of alcohol for 20 years and has maintained continuous funding from the National Institutes of Health—National Institute on Alcohol Abuse and Alcoholism for close to 15 years. His research during this time has focused on the behavioral genetics of rat lines selectively bred to consume high, vs very low, amounts of ethanol. The high ethanol-consuming rat lines display intakes corresponding with that of a 70 kg male drinking a fifth, or more, of 90-proof whiskey every day. These rat lines display many of the behavioral, physiological, neurochemical and genetic characteristics observed in clinical family history positive (FHP), for alcoholism, individuals; whereas the low ethanol-consuming rat lines serve as an animal model of family history negative (FHN) individuals. Moreover, these high ethanol-consuming rat lines meet established criteria for an animal model of alcoholism. Regarding this, he has written extensively on the genotypic as well as behavioral and neurochemical phenotypic characteristics of these and other major, international selectively bred high vs low ethanol-consuming rat lines. His more recent research has focused on three major areas: (1) innate and ethanol-induced changes in gene expression within subregions of the mesocorticolimbic and extended amygdala reward neurocircuits; (2) the acute as well as chronic behavioral and neurochemical effects of ethanol and/or nicotine exposure during adolescence and emerging adulthood; and (3) differences in the genetic, behavioral and neurochemical effects of binge-like, non-binge-like and relapse-like ethanol drinking and/or nicotine consumption. Scholastically, Dr. Bell has presented his findings to professional and lay audiences locally, nationally and internationally. He has published approximately 120 journal articles and book chapters. He serves as Associate Editor, Review Editor or Reviewer for over 50 international journals. He serves as a grant reviewer for the Veterans Affairs and the National Institutes of Health as well as multiple international academic institutions and is a member of the Research Society on Alcoholism—Animal Research and Ethics Committee.
Affiliations and expertise
Associate Professor, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USASR
Shafiqur Rahman
Shafiqur Rahman, Ph.D. is Professor of Pharmacology in the Department of Pharmaceutical Sciences at South Dakota State University (SDSU) in Brookings, USA. He received his Ph.D. in Neuropharmacology from the Memorial University of Newfoundland, Canada. Dr. Rahman completed his post-doctoral fellowship in the Department of Psychiatry from Indiana University School of Medicine in Indianapolis in USA. Prior to joining SDSU, he worked as research scientist and faculty at the University of Kentucky in Lexington, USA and the University of Toronto, Canada. Dr. Rahman's research focus is drug discovery in neuropharmacology, i.e. the development of novel therapeutic candidates for the treatment of drug addiction and neuropsychiatric disorders. His research and scholarship has resulted in over 125 publications and 11 edited books/book chapters. Dr. Rahman served as editor, editorial board member and reviewer for numerous Scientific Journals and review panels related to drug addiction, neuropharmacology, and drug discovery research. Dr. Rahman is also a member of several professional societies or organizations, including Society for Neuroscience, American Society for Experimental Neurotherapeutics, and American Society for Pharmacology and Experimental Therapeutics.
Affiliations and expertise
Professor, Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD, USARead Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II on ScienceDirect