Advances in Clinical Chemistry
- 1st Edition, Volume 105 - November 2, 2021
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 6 2 7 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 1 1 1 - 4
Advances in Clinical Chemistry, Volume 105, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laborator… Read more
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Request a sales quoteAdvances in Clinical Chemistry, Volume 105, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on IgG N-glycans, Extracellular Vesicles: Potential Impact on Cardiovascular Diseases, Advances in Bone Turnover Markers, Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases in Kidney Disease, and The Prothrombotic State in Cancer.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
Clinical Laboratory Professionals, Physicians and Research Scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: IgG N-glycans
- Abstract
- 1: Introduction
- 2: IgG N-glycan repertoire
- 3: Functional impact of IgG N-glycosylation
- 4: Characterization of IgG N-glycans
- 5: Recent developments in IgG glycans
- 6: Summary and future perspectives
- Acknowledgment
- References
- Chapter Two: Extracellular vesicles: Potential impact on cardiovascular diseases
- Abstract
- 1: Introduction
- 2: Biological functions of EVs
- 3: EVs and cardiovascular diseases
- 4: Diagnostic and therapeutic potential of EVs in CVDs
- 5: Conclusion and perspective
- References
- Chapter Three: Advances in bone turnover markers
- Abstract
- 1: Introduction
- 2: Conclusions
- References
- Chapter Four: Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in kidney disease
- Abstract
- 1: Introduction
- 2: MMPs and TIMPs expression in the kidney
- 3: MMPs in kidney development
- 4: MMPs and TIMPs in kidney fibrosis
- 5: MMPs and TIMPs in glomerular disease
- 6: MMPs and TIMPs in diabetic kidney disease
- 7: MMPs and TIMPs in polycystic kidney disease
- 8: MMPs and TIMPs in chronic kidney disease
- 9: MMPs and TIMPs in acute kidney injury
- 10: MMPs and TIMPs in kidney transplantation
- 11: MMPs and TIMPs in renal tumors
- 12: Gene polymorphism regulating MMPs in kidney disease
- 13: Development of novel synthetic inhibitors of MMPs
- 14: Summary
- References
- Chapter Five: The prothrombotic state in cancer
- Abstract
- 1: Introduction
- 2: Cancer and thrombosis
- 3: Hemostasis and thromboembolism
- 4: The prothrombotic state in cancer
- 5: Proteomic and genomic factors
- 6: Mechanisms of the prothrombotic state
- 7: Antibodies and the pro-coagulant states
- 8: Summary
- 9: Perspective
- References
- Chapter Six: Urinary biohazard markers in firefighters
- Abstract
- 1: Introduction
- 2: Biomarkers of effect
- 3: Biomarkers of exposure
- 4: Conclusions and future perspectives
- Acknowledgments
- References
- Index
- Edition: 1
- Volume: 105
- Published: November 2, 2021
- No. of pages (Hardback): 338
- No. of pages (eBook): 338
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128246276
- eBook ISBN: 9780323851114
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect