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Elsevier

Academic Press

  • Microbiome, Immunity, Digestive Health and Nutrition

    Epidemiology, Pathophysiology, Prevention and Treatment
    • 1st Edition
    • Debasis Bagchi + 1 more
    • English
    Microbiome, Immunity, Digestive Health and Nutrition: Epidemiology, Pathophysiology, Prevention and Treatment addresses a wide range of topics related to the role of nutrition in achieving and maintaining a healthy gut microbiome. Written by leading experts in the field, the book outlines the various foods, minerals, vitamins, dietary fibers, prebiotics, probiotics, nutritional supplements, phytochemicals and drugs that improve gut health. It specifically addresses molecular and cellular mechanisms and pathways by which these nutritional components contribute to the physiology and functionality of a healthy gut microbiome and gut health. Intended for nutrition researchers and practitioners, food experts, gastroenterologists, nurses, general practitioners, public health officials and health professionals, this book is sure to be a welcomed resource.

  • Plant Exposure to Engineered Nanoparticles

    Uptake, Transformation, Molecular and Physiological Responses
    • 1st Edition
    • Cyren Rico
    • English
    Plant Exposure to Engineered Nanoparticles: Uptake, Transformation, Molecular and Physiological Responses discusses the long-term exposure of plants, including agronomic crops, to nanomaterials in terrestrial environments. Chapters discuss changes in metabolite profiles in plants exposed to engineered nanomaterials, as well as modifications in elemental content of edible portions of plants. Biochemical pathways, root profiles, generational exposure, and biomass productivity are also analyzed in detail. Subsequent chapters cover risks to trophic transfer, as well as human health and ecological functions, before concluding with future approaches to plant-nanomaterial research. The book covers important aspects of the interactions between plant and nanomaterials and will be a valuable resource to scientists and researchers in plant physiology, nanotechnology, agronomy and environmental science.

  • Interactions of Bone with Orthopedic Implants and Possible Failures

    • 1st Edition
    • Amirhossein Goharian + 1 more
    • English
    Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue.

  • MicroRNA

    From Bench to Bedside
    • 1st Edition
    • Junjie Xiao
    • English
    MicroRNA: From Bench to Bedside provides an in-depth, expansive overview of microRNA from fundamentals to clinical practice. It presents researchers with detailed insights on the topic of microRNA, exploring foundational knowledge that is followed by methodologies and the latest technologies for research and potential theragnostic and therapeutic applications for specific diseases. The book consists of eight parts, beginning with an introduction to microRNA and the current state of the field, followed by sections on biogenesis and maturation of microRNA, and methodology and bioinformatics, where chapters focus on isolation and detection techniques. Sections then move on to molecular mechanisms and gene regulation, considering topics such as transcriptional regulation and epigenetic regulation, as well as the role of microRNA as biomarkers. Additionally, microRNA and human disease and microRNA-based therapeutics are explored, focusing on a wide range of diseases such as cancer, age-related disease, cardiovascular disease, microRNA targeted therapy in hepatitis and therapeutic strategies for diabetes. The book concludes with a discussion on advances and future perspectives in microRNA investigation.

  • Carotenoids: Carotenoid and Apocarotenoid Analysis

    • 1st Edition
    • English
    Carotenoids: Carotenoid and Apocarotenoid Analysis, Volume 670, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume covering Getting to know carotenoids, Laser capture of tissues for micro-scale carotenoid analyses, Metabolic engineering of carotenoids: procedures for metabolomic characterization, LC-MS analysis of intracellular metabolites for precursors to the carotenoid pathway, Use of E. coli to produce carotenoid standards, HPLC analysis of carotenoids from Bacteria, Purification and development of standards for carotenoid quantification in plant tissues, and much more. Additional sections in this release cover Ultra-High Performance Liquid Chromatography-Mass Spectrometry Analysis of Plant Apocarotenoids, Detection and analysis of novel and known volatile plant apocarotenoids, Carotenoid extraction, detection, and analysis in citrus, Strategies For The Separation And Tentative Identification Of Geometrical (Cis/Trans, Z/E) Isomers Of Carotenoids, Use of stable isotopes to study bioconversion and bioefficacy of pro-vitamin A carotenoids, Carotenoid extraction and analysis of blood plasma/serum, and more.</P>

  • Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

    • 1st Edition
    • Sandeep Kumar Singh + 2 more
    • English
    Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.

  • Closed Nuclear Fuel Cycle with Fast Reactors

    Handbook of Russian Nuclear Power
    • 1st Edition
    • Evgeny Adamov
    • English
    Closed Nuclear Fuel Cycle with Fast Reactors: Handbook of Russian Nuclear Power provides unique insights into research and practical activities from leading Russian experts. It presents readers with unprecedented insight and essential knowledge surrounding nuclear fast reactor technologies, as well as novel methods to close the nuclear fuel cycle to achieve cleaner, more environmentally friendly, and more efficient nuclear power. Using the Proryv Project as a framework, the book's contributors provide detailed descriptions of technologies in development in Russia, allowing readers from around the globe to gain a thorough understanding which they can then apply to their own research and practice. Nuclear engineers and technologists of fast reactors, advanced reactors and fuel cycles will use this book as a guide to inform new technology development. They will be able to use the experiences from the Proryv Project to drive fast reactor development with closed fuel cycles for the future.

  • Omics in Horticultural Crops

    • 1st Edition
    • Gyana Ranjan Rout + 1 more
    • English
    Omics in Horticulture Crops presents a comprehensive view of germplasm diversity, genetic evolution, genomics, proteomics and transcriptomics of fruit crops (temperate, tropical and subtropical fruits, fruit nuts, berries), vegetables, tuberous crops, ornamental and floricultural crops and medicinal aromatic plants. Information covering phenomics, genetic diversity, phylogenetic studies, genome sequencing, and genome barcoding through the utilization of molecular markers plays an imperative role in the characterization and effective utilization of diverse germplasm are included in the book. This is a valuable reference for researchers and academics seeking to improve cultivar productivity through enhanced genetic diversity while also retaining optimal traits and protecting the growing environment.

  • Systems of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Spaceflight Associated Neuro-Ocular Syndrome

    • 1st Edition
    • Andrew G. Lee + 1 more
    • English
    Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity-associa... findings collectively define the Spaceflight Associated Neuro-ocular Syndrome (SANS). In this book, the editors compare and contrast prior published work on SANS by the National Aeronautics and Space Administration’s (NASA) Space Medicine Operations Division with retrospective and prospective studies from other research groups. The book describes the possible mechanisms and potential etiologies for SANS, and provides an update and review on the clinical manifestations of SANS including: unilateral and bilateral optic disc edema, globe flattening, choroidal and retinal folds, hyperopic refractive error shifts, and focal areas of ischemic retina (i.e., cotton wool spots). The ocular imaging findings (e.g., retinal nerve fiber layer, optic disc, and choroidal changes on optical coherence tomography) of SANS is also described, including the intraorbital and intracranial findings on orbital ultrasound and magnetic resonance imaging. The knowledge gaps for in-flight and terrestrial human research including potential countermeasures for future stud is also explored, including reports on the in-flight and terrestrial human and animal research being investigated by NASA and its partners to study SANS both prospectively and longitudinally and in preparation for future long duration manned missions to space including the moon, the asteroid belt, or Mars. We think this is a unique topic and hope that NASA and its research partners continue to study SANS in preparation for future longer duration manned space missions.

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