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Elsevier

Academic Press

  • Carotenoids: Carotenoid and Apocarotenoid Analysis

    • 1st Edition
    • English
    Carotenoids: Carotenoid and Apocarotenoid Analysis, Volume 670, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume covering Getting to know carotenoids, Laser capture of tissues for micro-scale carotenoid analyses, Metabolic engineering of carotenoids: procedures for metabolomic characterization, LC-MS analysis of intracellular metabolites for precursors to the carotenoid pathway, Use of E. coli to produce carotenoid standards, HPLC analysis of carotenoids from Bacteria, Purification and development of standards for carotenoid quantification in plant tissues, and much more. Additional sections in this release cover Ultra-High Performance Liquid Chromatography-Mass Spectrometry Analysis of Plant Apocarotenoids, Detection and analysis of novel and known volatile plant apocarotenoids, Carotenoid extraction, detection, and analysis in citrus, Strategies For The Separation And Tentative Identification Of Geometrical (Cis/Trans, Z/E) Isomers Of Carotenoids, Use of stable isotopes to study bioconversion and bioefficacy of pro-vitamin A carotenoids, Carotenoid extraction and analysis of blood plasma/serum, and more.</P>

  • Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

    • 1st Edition
    • Sandeep Kumar Singh + 2 more
    • English
    Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.

  • MicroRNA

    From Bench to Bedside
    • 1st Edition
    • Junjie Xiao
    • English
    MicroRNA: From Bench to Bedside provides an in-depth, expansive overview of microRNA from fundamentals to clinical practice. It presents researchers with detailed insights on the topic of microRNA, exploring foundational knowledge that is followed by methodologies and the latest technologies for research and potential theragnostic and therapeutic applications for specific diseases. The book consists of eight parts, beginning with an introduction to microRNA and the current state of the field, followed by sections on biogenesis and maturation of microRNA, and methodology and bioinformatics, where chapters focus on isolation and detection techniques. Sections then move on to molecular mechanisms and gene regulation, considering topics such as transcriptional regulation and epigenetic regulation, as well as the role of microRNA as biomarkers. Additionally, microRNA and human disease and microRNA-based therapeutics are explored, focusing on a wide range of diseases such as cancer, age-related disease, cardiovascular disease, microRNA targeted therapy in hepatitis and therapeutic strategies for diabetes. The book concludes with a discussion on advances and future perspectives in microRNA investigation.

  • Closed Nuclear Fuel Cycle with Fast Reactors

    Handbook of Russian Nuclear Power
    • 1st Edition
    • Evgeny Adamov
    • English
    Closed Nuclear Fuel Cycle with Fast Reactors: Handbook of Russian Nuclear Power provides unique insights into research and practical activities from leading Russian experts. It presents readers with unprecedented insight and essential knowledge surrounding nuclear fast reactor technologies, as well as novel methods to close the nuclear fuel cycle to achieve cleaner, more environmentally friendly, and more efficient nuclear power. Using the Proryv Project as a framework, the book's contributors provide detailed descriptions of technologies in development in Russia, allowing readers from around the globe to gain a thorough understanding which they can then apply to their own research and practice. Nuclear engineers and technologists of fast reactors, advanced reactors and fuel cycles will use this book as a guide to inform new technology development. They will be able to use the experiences from the Proryv Project to drive fast reactor development with closed fuel cycles for the future.

  • Spaceflight Associated Neuro-Ocular Syndrome

    • 1st Edition
    • Andrew G. Lee + 1 more
    • English
    Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity-associa... findings collectively define the Spaceflight Associated Neuro-ocular Syndrome (SANS). In this book, the editors compare and contrast prior published work on SANS by the National Aeronautics and Space Administration’s (NASA) Space Medicine Operations Division with retrospective and prospective studies from other research groups. The book describes the possible mechanisms and potential etiologies for SANS, and provides an update and review on the clinical manifestations of SANS including: unilateral and bilateral optic disc edema, globe flattening, choroidal and retinal folds, hyperopic refractive error shifts, and focal areas of ischemic retina (i.e., cotton wool spots). The ocular imaging findings (e.g., retinal nerve fiber layer, optic disc, and choroidal changes on optical coherence tomography) of SANS is also described, including the intraorbital and intracranial findings on orbital ultrasound and magnetic resonance imaging. The knowledge gaps for in-flight and terrestrial human research including potential countermeasures for future stud is also explored, including reports on the in-flight and terrestrial human and animal research being investigated by NASA and its partners to study SANS both prospectively and longitudinally and in preparation for future long duration manned missions to space including the moon, the asteroid belt, or Mars. We think this is a unique topic and hope that NASA and its research partners continue to study SANS in preparation for future longer duration manned space missions.

  • Systems of Nanovesicular Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 3 more
    • English
    Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles. This volume discusses cubosomes, proniosomes and niosomes, dendrimerosomes and other new and effective approaches for drug delivery. It will be a valuable title and resource for academics and pharmaceutical scientists, including industrial pharmacists, analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailor-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource.

  • Omics in Horticultural Crops

    • 1st Edition
    • Gyana Ranjan Rout + 1 more
    • English
    Omics in Horticulture Crops presents a comprehensive view of germplasm diversity, genetic evolution, genomics, proteomics and transcriptomics of fruit crops (temperate, tropical and subtropical fruits, fruit nuts, berries), vegetables, tuberous crops, ornamental and floricultural crops and medicinal aromatic plants. Information covering phenomics, genetic diversity, phylogenetic studies, genome sequencing, and genome barcoding through the utilization of molecular markers plays an imperative role in the characterization and effective utilization of diverse germplasm are included in the book. This is a valuable reference for researchers and academics seeking to improve cultivar productivity through enhanced genetic diversity while also retaining optimal traits and protecting the growing environment.

  • Applications of Biosurfactant in Agriculture

    • 1st Edition
    • Inamuddin + 1 more
    • English
    Applications of Biosurfactant in Agriculture explores the use of beneficial microorganisms as an alternative to current synthetic plant protection strategies. The book highlights a range of renewable raw substrates including agro-industrial waste as a dependable and cost-effective technology for the mass production of biosurfactant, emphasizes the formulation of biosurfactants using a full-factorial design, scientometric assessment, and presents mathematical modeling for the enhancement of production processes. Recent biotechnological techniques such as functional metagenomics that could help in the molecular characterization of novel biosurfactant with multifunctional activities majorly from uncultured and unexploited microbes available in the soil biosphere are also explored.This book identifies possible modes of action by which nutrients are normally released to plants through the formation of metal-biosurfactant complexes and presents recent research findings on the utilization of biosurfactants for the management of mycotoxins and microorganisms when evaluated in the field and in greenhouses. Finally, the book emphasizes the application of biosurfactants as a form of potent antibiotics for the management of several zoonotic diseases and in animal husbandry.

  • Introduction to Basic Aspects of the Autonomic Nervous System

    Volume 1
    • 6th Edition
    • Otto Appenzeller + 2 more
    • English
    Introduction to Basic Aspects of the Autonomic Nervous System, Sixth Edition, Volume One is an all-encompassing reference on the autonomic nervous system's basic function, dysfunction and pathology. This volume describes the anatomy of the autonomic nervous system and its role in the regulation of blood pressure, body temperature, respiration, micturition, digestion and renal function. Additional chapters focus on the autonomic modulation of the neuroendocrine system, sexual function, and immunity. There is also a chapter on mummies and the autonomic nervous system. With these chapters, readers will gain extensive knowledge on the autonomic nervous system's anatomy, functional organization and neurochemistry, which is critical to care for patients with autonomic disorders and guide patient-oriented research.

  • Occupational Neurotoxicology

    • 1st Edition
    • Volume 7
    • English
    Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods.

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