Skip to main content
Elsevier

Academic Press

  • Epigenetic Cancer Therapy

    • 2nd Edition
    • Steven Gray
    • English
    Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering.

  • The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress

    • 1st Edition
    • Anket Sharma + 4 more
    • English
    The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress is a comprehensive resource on all major PGRs. These include auxins, cytokinins, jasmonates, polyammines, plant growth promoting rhizobacteria (PGPR), and more. In the last two decades, researchers have explored a lot about the roles of plant growth regulators (PGRs) in boosting the resistance of plants under stress conditions. These PGRs acts as stimulators for various physiological processes by regulating key cell signaling pathways. This title is an essential read for any scientist wanting to understand the latest advances in combatting abiotic stresses using plant growth regulators.In the present era, plants are facing a lot of challenges during their lifecycle, including growth declines due to abiotic stress. The main abiotic stresses threatening plants are water scarcity, salinity, extreme temperatures, heavy metals and pesticides. These stresses directly or indirectly cause toxicity to plants, causing hindrance to their growth and development, and ultimately reduce plant productivity.

  • Athlete’s Heart

    A Multimodal Approach – From Physiological to Pathological Cardiac Adaptations
    • 1st Edition
    • Antonello D’Andrea + 1 more
    • English
    Athlete's Heart: A Multimodal Approach – From Physiological to Pathological Cardiac Adaptations provides a complete overview of all adaptations of the heart to sport practice by highlighting the different diagnosis between athlete’s heart and pathological remodeling. Written by international experts in the field, chapters discuss ECG findings, echocardiogram data, cardiac magnetic resonance and new forms of multimodality imaging, providing readers with evidence-based guidance on how to differentiate athlete's heart from cardiomyopathies. Athlete's heart is the term given to a constellation of cardiac structural, functional and electrical remodeling that accompanies regular athletic training. Due to the substantial phenotypic overlap between electrical and structural changes observed in the physiological athletic heart remodeling and pathological changes resulted from inherited or acquired cardiomyopathies, distinguishing between adaptive and maladaptive cardiovascular response to exercise is a challenging task.

  • Sulfurtransferases

    Essential Enzymes for Life
    • 1st Edition
    • Noriyuki Nagahara
    • English
    Sulfurtransferases: Essential Enzymes for Life stands as the first comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, each chapter covers a specific sulfurtransferase, including its basic biology and roles in healthy functioning, disease, drug discovery, and other biotechnological applications. The physiological function for each enzyme is considered in depth, along with regulation mechanisms, pharmacological inhibitors, and pathology and conditions related to altered enzymatic activity. Sulfurtransferases discussed include rhodanese, MST, thiosulfate-thiol sulfurtransferase, tRNA uracil 4-sulfurtransferase, thiosulfate-dithiol sulfurtransferases, biotin synthase, cysteine desulfurase, lipoyl synthase, molybdenum cofactor sulfurtransferase, thiazole synthase, molybdopterin synthase sulfurtransferase, molybdopterin synthase, tRNA-uridine 2-sulfurtransferase, tRNA-5-taurinomethyl... 2-sulfurtransferase, tRNA-5-methyluridine (54) 2-sulfurtransferase, and L-aspartate semialdehyde sulfurtransferase, among others. Here, researchers will discover key knowledge and recent advances to bring forward new studies on this increasingly relevant class of enzymes, while clinicians may apply new findings in medical practice.

  • Diagnostic Biomedical Signal and Image Processing Applications With Deep Learning Methods

    • 1st Edition
    • Kemal Polat + 1 more
    • English
    Diagnostic Biomedical Signal and Image Processing Applications with Deep Learning Methods presents comprehensive research on both medical imaging and medical signals analysis. The book discusses classification, segmentation, detection, tracking and retrieval applications of non-invasive methods such as EEG, ECG, EMG, MRI, fMRI, CT and X-RAY, amongst others. These image and signal modalities include real challenges that are the main themes that medical imaging and medical signal processing researchers focus on today. The book also emphasizes removing noise and specifying dataset key properties, with each chapter containing details of one of the medical imaging or medical signal modalities. Focusing on solving real medical problems using new deep learning and CNN approaches, this book will appeal to research scholars, graduate students, faculty members, R&D engineers, and biomedical engineers who want to learn how medical signals and images play an important role in the early diagnosis and treatment of diseases.

  • Infectious Diseases

    Smart Study Guide for Medical Students, Residents, and Clinical Providers
    • 1st Edition
    • Saif ul Islam
    • English
    Infectious Diseases: Smart Study Guide for Medical Students, Residents, Physicians and Clinical Pharmacists attempts to consolidate knowledge and information into a step-by-step process that would be easy to understand, remember, and apply in a clinical setting. High-yield information presented in this book is necessary for medical students and residents. This book has provided information for all disciplines working in infectious diseases, whether students, residents, physicians, pharmacists, or nurses. The book is organized for quick and easy to retrieve information for all professionals.

  • Multi-Criteria Decision-Making Sorting Methods

    Applications to Real-World Problems
    • 1st Edition
    • Luis Martinez Lopez + 3 more
    • English
    Multi Criteria Decision Making (MCDM) is a generic term for all methods that help people making decisions according to their preferences, in situations where there is more than one conflicting criterion. It is a branch of operational research dealing with finding optimal results in complex scenarios including various indicators, conflicting objectives and criteria. The approach of MCDM involves decision making concerning quantitative and qualitative factors.　　 The importance and success of MCDM are due to the fact that they have successfully dealt with different types of problematics for supporting decision makers such as choice, ranking and sorting, description.　　 Even though, each of the different problematics in MCDM is important, Multi-Criteria Decision-Making Sorting Methods will focus on sorting approaches across a wide range of interesting techniques and research disciplines. The applications which have been and can be solved by these techniques are more and more important in current real-world decision-making problems. Therefore, the book provides a clear overview of MCDM sorting methods and the different tools which can be used to solve real-world problems by revising such tools and characterizing them according to their performance and suitability for different types of problems. The book is aimed at a broad audience including computer scientists, engineers, geography and GIS experts, business and financial management experts, environment experts, and all those professional people interested in MCDM and its applications. The book may also be useful for teaching MCDM courses in fields such as industrial management, computer science, and applied mathematics, as new developments in multi-criteria decision making.

  • Renewable Energy - Volume 1: Solar, Wind, and Hydropower

    Definitions, Developments, Applications, Case Studies, and Modelling and Simulation
    • 1st Edition
    • Abdul Ghani Olabi
    • English
    Renewable Energy - Volume 1: Solar, Wind, and Hydropower: Definitions, Developments, Applications, Case Studies, and Modelling and Simulation is a comprehensive resource for those wanting an authoritative volume on the significant aspects of these rapidly growing renewable technologies. Providing a structured approach to the emerging technologies and advances in the implementation of solar, wind and hydro energy, the book offers the most requested and desirable practical elements for the renewable industry. Sections cover definitions, applications, modeling and analysis through case study and example. This coordinated approach allows for standalone, accessible, and functioning chapters dedicated to a particular energy source, giving researchers and engineers an important and unique consolidated source of information on all aspects of these state-of-the-art fields.

  • Automata Theory and Formal Languages

    • 1st Edition
    • Pallavi Vijay Chavan + 1 more
    • English
    Automata Theory and Formal Languages presents the difficult concepts of automata theory in a straightforward manner, including discussions on diverse concepts and tools that play major roles in developing computing machines, algorithms and code. Automata theory includes numerous concepts such as finite automata, regular grammar, formal languages, context free and context sensitive grammar, push down automata, Turing machine, and decidability, which constitute the backbone of computing machines. This book enables readers to gain sufficient knowledge and experience to construct and solve complex machines. Each chapter begins with key concepts followed by a number of important examples that demonstrate the solution. The book explains concepts and simultaneously helps readers develop an understanding of their application with real-world examples, including application of Context Free Grammars in programming languages and Artificial Intelligence, and cellular automata in biomedical problems.

  • Investment Banks, Hedge Funds, and Private Equity

    • 4th Edition
    • David P. Stowell + 1 more
    • English
    Investment Banks, Hedge Funds, and Private Equity, Fourth Edition provides a real-world view of this fast-evolving field, reviewing and analyzing recent innovations and developments. This reference captures the actual work of bankers and professional investors, providing readers with templates for real transactions and insight on how investment banks, hedge funds, and private equity firms provide services to each other while creating opportunities for corporations and investors to raise capital, invest, hedge, finance, acquire, divest, and risk manage. For each type of institution, the business model, organizational structure, products, challenges, regulatory issues, and profit-making opportunities are explained. In addition, specific transactions are analyzed to make clear how advisory services, financings, investments, and trades produce profits or losses, and which types of risks are most commonly taken by each type of institution. Importantly, the linkage of investment banks, hedge funds, and private equity to corporations, governments, and individuals is described, enabling the reader to more clearly understand how these organizations impact them and how their products and services can be best utilized.

Browse by Publisher