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Academic Press

  • Advances in Extraction and Applications of Bioactive Phytochemicals

    • 1st Edition
    • Mihir Kumar Purkait + 2 more
    • English
    Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more. This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource.

  • Numerical Methods in Turbulence Simulation

    • 1st Edition
    • Robert Moser
    • English
    Numerical Methods in Turbulence Simulation provides detailed specifications of the numerical methods needed to solve important problems in turbulence simulation. Numerical simulation of turbulent fluid flows is challenging because of the range of space and time scales that must be represented. This book provides explanations of the numerical error and stability characteristics of numerical techniques, along with treatments of the additional numerical challenges that arise in large eddy simulations. Chapters are written as tutorials by experts in the field, covering specific both contexts and applications. Three classes of turbulent flow are addressed, including incompressible, compressible and reactive, with a wide range of the best numerical practices covered. A thorough introduction to the numerical methods is provided for those without a background in turbulence, as is everything needed for a thorough understanding of the fundamental equations. The small scales that must be resolved are generally not localized around some distinct small-scale feature, but instead are distributed throughout a volume. These characteristics put particular strain on the numerical methods used to simulate turbulent flows.

  • Cardiopulmonary Bypass

    Advances in Extracorporeal Life Support
    • 1st Edition
    • Kaan Kırali + 2 more
    • English
    Cardiopulmonary Bypass: Advancements in Extracorporeal Life Support provides comprehensive coverage on the technological developments and clinical applications of extracorporeal technologies, including the underlying basic science and the latest clinical advances in the field. Written by experts around the world, this book comprises all characteristics of cardiopulmonary bypass as well as chapters regarding equipment, physiology and pathology, pediatric aspects and clinical applications. Important highlights include the latest updates regarding minimal invasive cardiopulmonary bypass (MICPB), extracorporeal circulatory and respiratory support (ECCRS) in cardiac and non-cardiac patients, ECMO support in COVID-19, and updated guidelines of extracorporeal technologies. This book is an invaluable resource to clinicians, researchers and medical students in the fields of cardiothoracic surgery, cardiac anesthesiology, intensive care, and perfusion technology.

  • Neurocircuitry of Addiction

    • 1st Edition
    • Nicholas W. Gilpin
    • English
    People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction.

  • Genomic Data Sharing

    Case Studies, Challenges, and Opportunities for Precision Medicine
    • 1st Edition
    • Jennifer B. Mccormick + 1 more
    • English
    Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine provides a comprehensive overview of current and emerging issues in genomic data sharing. In this book, international leaders in genomic data examine these issues in-depth, offering practical case studies that highlight key successes, challenges and opportunities. Sections discuss the eMERGE Network, Undiagnosed Disease Network, Vanderbilt Biobank, Marshfield Clinic Biobank, Minnesota Authorization, Rochester Epidemiology Project, NIH sponsored biobanks, GINA, and Global Alliance for Genomics and Health (GA4GH). In addition to these perspectives from the frontlines, the book also provides succinct overviews of ethical, legal, social and IT challenges.Clinician investigators, clinicians affiliated with academic medical centers, policymakers and regulators will also gain insights that will allow them to navigate the increasingly complex ethical, social and clinical landscape of genomic data sharing.

  • Agricultural Bioeconomy

    Innovation and Foresight in the Post-COVID Era
    • 1st Edition
    • Chetan Keswani + 3 more
    • English
    Agricultural Bioeconomy: Innovation and Foresight in the Post-COVID Era presents recent advancements in biotechnology, exploring the optimal utilization of technologies to provide rapid and impactful economic recovery and sustainable resources in a future that will bear the mark of COVID-19. Understanding that there is a necessary balance between risk and reward, this book provides a foundational hypothesis as well as operational direction for addressing the commercialization and regulatory issues in a bio-based economy where agricultural output is at the core. By presenting adaptable practices to successfully establish and progress agri-based global bioeconomies, the book features a new paradigm focused on technological foresight and response to future risks and disasters. Key considerations include assessing and managing the urban bioeconomy, climate change mitigation, biofuels and bioenergy, GMOs, and employment generation. This book provides the solid next step toward future-proofing global economies using a combination of agricultural technologies and economic goals. Professionals and advanced students focused on the production of renewable biological resources and their conversion into value-added products including food, feed, bio-based products, and bioenergy will find this book useful.

  • Modeling and Nonlinear Robust Control of Delta-Like Parallel Kinematic Manipulators

    • 1st Edition
    • Jonatan Martin Escorcia Hernandez + 2 more
    • English
    Modeling and Nonlinear Robust Control of Delta-Like Parallel Kinematic Manipulators deals with the modeling and control of parallel robots. The book's content will benefit students, researchers and engineers in robotics by providing a simplified methodology to obtain the dynamic model of parallel robots with a delta-type architecture. Moreover, this methodology is compatible with the real-time implementation of model-based and robust control schemes. And, it can easily extend the proposed robust control solutions to other robotic architectures.

  • State of the Art in Neural Networks and Their Applications

    Volume 2
    • 1st Edition
    • Jasjit S. Suri + 1 more
    • English
    State of the Art in Neural Networks and Their Applications, Volume Two presents the latest advances in artificial neural networks and their applications across a wide range of clinical diagnoses. The book provides over views and case studies of advances in the role of machine learning, artificial intelligence, deep learning, cognitive image processing, and suitable data analytics useful for clinical diagnosis and research applications. The application of neural network, artificial intelligence and machine learning methods in biomedical image analysis have resulted in the development of computer-aided diagnostic (CAD) systems that aim towards the automatic early detection of several severe diseases. State of the Art in Neural Networks and Their Applications is presented in two volumes. Volume One: Neural Networks in Oncology Imaging covers lung cancer, prostate cancer, and bladder cancer. Volume Two: Neural Networks in Brain Disorders and Other Diseases covers autism spectrum disorder, Alzheimer’s disease, attention deficit hyperactivity disorder, hypertension, and other diseases. Written by experienced engineers in the field, these two volumes will help engineers, computer scientists, researchers, and clinicians understand the technology and applications of artificial neural networks.

  • Neglected and Underutilized Crops

    Future Smart Food
    • 1st Edition
    • Muhammad Farooq + 1 more
    • English
    Neglected and Underutilized Crops: Future Smart Food explores future food crops with climate resilience potential. Sections cover their botany, nutritional significance, global distribution, production technology, and tolerance to biotic and abiotic stresses of neglected and underutilized crops. By simply changing species in a crop rotation system, the cycle of some pests and diseases is disrupted and probabilities of infestations are reduced. Finally, the book provides case studies that highlight where the adaptation of crops to local environments, especially with regard to climate change, have been successful.These crops can help make agricultural production systems more resilient to climate change. Although a few books on neglected and underutilized crops are available, this comprehensive book covers the full scope of crop husbandry, nutritional significance and global distribution.

  • Spinal Interneurons

    Plasticity after Spinal Cord Injury
    • 1st Edition
    • Lyandysha Viktorovna Zholudeva + 1 more
    • English
    The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to persistent activity, neural injury, or in response to disease. Although, by definition, their axons are restricted to the same structure as the soma (in this case the spinal cord), spinal interneurons are capable of sprouting and rewiring entire neural circuits, and contribute to some restoration of disrupted neural communication after injury to the spinal cord (i.e., “bypassing” the lesion site). Spinal Interneurons provides a focused overview of how scientists classify interneurons in general, the techniques used to identify subsets of interneurons, their roles in specific neural circuits, and the scientific evidence for their neuroplasticity. Understanding the capacity for neuroplasticity and identity of specific spinal interneurons that are optimal for recovery, may help determine cellular candidates for developing therapies. Spinal Interneurons provides neuroscientists, clinicians, and trainees a reference book exclusively concentrating on spinal interneurons, the techniques and experiments employed to identify and study these cells as part of normal and compromised neural circuits, and highlights the therapeutic potential of these cells by presenting the relevant pre-clinical and clinical work to date. People in industry will also benefit from this book, which compiles the latest in therapeutic strategies for targeting spinal interneurons, what considerations there are for the development and use of treatments, and how such treatments can not only be translated to the clinic, but how existing treatments should be appropriately reverse-translated to the bench.

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