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Academic Press

  • Antioxidant Methods

    A Guideline for Understanding and Determining Antioxidant Capacity
    • 1st Edition
    • Francisco Avelino
    • English
    Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.
  • Advances in Agronomy

    • 1st Edition
    • Volume 185
    • English
    Advances in Agronomy, Volume 185, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.
  • Protein Digestion-Derived Peptides

    Chemistry, Bioactivity, and Health Effects
    • 1st Edition
    • Cristina Martinez-Villaluenga + 1 more
    • English
    Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects presents the latest international advances in fundamental and applied research on the impact of gastrointestinal digestion on the release of bioactive peptides from food sources.This book covers the fundamentals and applications of gastrointestinal digestion and absorption models as well as the impact of food matrices, their components and protein characteristics, and peptide bioactivity, bioaccessibility, and bioavailability. Moreover, the book expands coverage in vitro and in vivo approaches to simulate gastrointestinal digestion of food proteins and absorption models to evaluate the bioaccessibility and bioavailability of released peptides.Developed for nutrition researchers, food scientists, and pharmaceutical scientists, this book is a welcomed resource for those who wish to understand the impact of peptides on chronic disease.
  • Microbial Biofilms

    Role in Human Infectious Diseases
    • 1st Edition
    • Mukesh Kumar Yadav + 2 more
    • English
    Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.
  • Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy

    • 1st Edition
    • Vivek Asati + 1 more
    • English
    Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1.The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets.
  • Liposomes in Drug Delivery

    What, Where, How and When to deliver
    • 1st Edition
    • Sophia G. Antimisiaris
    • English
    Liposomes in Drug Delivery: What, Where, How and When to Deliver is a concise, well-structured reference covering all the important issues related to the potential of this technology. Organized to provide practical information to researchers from any discipline with a particular therapeutic or bio-active substance to deliver, this book helps readers understand if liposomes can be of benefit for their particular need, what is the best type of liposome to use according to what needs to be delivered, where/when to deliver it, and how to design/prepare/chara... liposome properties for a particular application.The book is structured in Four parts. The first covers in a concise but in-depth way, what liposomes are, which are the liposome types, advantages/disadvant... and what is their stability, characterization methods, in vitro stability, and in vivo fate after different administration methods (routes). The second part focuses on the different mechanisms for liposomal drug delivery. Methodologies/techno... for manipulation of liposome structure/properties in order to design liposomes for particular delivery applications. Specific roadmaps for liposome design are discussed, including components to incorporate in liposomes for specific types of encapsulated molecules or specific routes of administration. The third part covers liposome applications for drug delivery. It focuses on specific delivery considerations for particular diseases. Finally, the fourth part covers methods of liposome fabrication.
  • Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

    • 1st Edition
    • Ting-Chao Chou
    • English
    “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.
  • Cranial Surgery - Part 1

    • 1st Edition
    • Volume 284
    • Jeremy Christopher Ganz
    • English
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.
  • Microbiome-Based Decontamination of Environmental Pollutants

    • 1st Edition
    • Ajay Kumar + 2 more
    • English
    Microbiome-Based Decontamination of Environmental Pollutants explores the complex interactions of plant-associated microbiomes, providing insights into the pressing challenges of managing environmental resources such as soil, water, and waste. Analysis has shown a formidable potential based in the network interactions between plant microbiota and environmental contaminants. This book presents insights into the potential exploitation of these plant-associated microbial functions. This volume in the Plant and Soil Microbiome series summarizes microbiological aspects of environmental management from the basics to advanced theoretical as well as practical aspects of microbial-based approaches.The physical and chemical changes caused by pollution of an ecosystem can occur rapidly, significantly impacting the functionality of ecosystem services in that environment. Environmental contamination poses and increasingly global challenge through direct and indirect adverse impacts on the climate, soil productivity and the health concerns of human beings. Traditional remediation techniques are not consistently feasible in mitigating environmental contaminants challenges in terms of cost-effectiveness, limited land resources and toxic residual products. The use of plant-associated microbes as part of a network of tools opens a new door to explore an alternative, eco-friendly and economical technology to mitigate the challenges of environmental contamination.
  • Techniques for Biochemical Analysis

    • 1st Edition
    • Khursheed Hussain + 3 more
    • English
    Techniques for Biochemical Analysis provides researchers with a practical guide for investigating a variety of different biomolecules. It includes a range of tried and tested protocols, outlining the principles upon which each technique is founded, as well as providing instructions on equipment setup and use, buffer preparation, reagents required, safety considerations and analysis of findings. Beginning with an introduction to biochemistry and laboratory procedures, the book moves on to specific methods focused on investigation of carbohydrates, proteins, enzymes, plant hormones, minerals, amino acids, and more.The large range of protocols covered in this foundational, how-to reference are interdisciplinary and adaptable to a variety of areas, making this an ideal resource for researchers across various fields, including biochemistry, molecular biology, medical sciences, plant physiology, agriculture, and related subjects.