Microbial Biofilms
Role in Human Infectious Diseases
- 1st Edition - April 10, 2024
- Editors: Mukesh Kumar Yadav, Jae Jun Song, Jorge E. Vidal
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 5 2 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 5 3 - 1
Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases re… Read more
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Request a sales quoteMicrobial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.
Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.
- Fulfills the knowledge gap in biofilm study
- Focuses on new and emerging concepts in microbial biofilm research
- Highlights the various anti-biofilm strategies
- Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases
Graduate students, Post-graduate students, along with researchers and PhD scholars working in the field of biotechnology, clinicians, scientists and industry personnel working on microbial biotechnology and medical microbiology, microbiology and immunology
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- 1. Application of nanoparticles to combat dental biofilms
- Abstract
- 1.1 Dental biofilms
- 1.2 Nanoparticles
- 1.3 Application of nanoparticles to treat dental biofilms
- 1.4 Treatment of periodontal disease
- 1.5 Future perspective on the applications of nanoparticles
- 1.6 Conclusion
- References
- 2. Streptococcus biofilms: role in human infectious diseases
- Abstract
- 2.1 Introduction
- 2.2 Classification of Streptococcus species
- 2.3 Biofilm mode of growth of Streptococcus species
- 2.4 Streptococcus biofilm-related infectious diseases
- 2.5 Conclusion and future perspective
- Acknowledgment
- References
- 3. Single-species and multispecies biofilms causing infections
- Abstract
- 3.1 Introduction
- 3.2 Role of biofilm in disease
- 3.3 Concluding remarks
- References
- 4. Gut microbiota: role of biofilms in human health
- Abstract
- 4.1 Introduction
- 4.2 Types of bacteria and their spatial distribution
- 4.3 The trajectory of gut microbiota in infants
- 4.4 Factors affecting gut microbiota
- 4.5 Microbial dysbiosis
- 4.6 Gut metabolite
- 4.7 Microbial biofilm
- 4.8 Conclusion
- References
- 5. Natural compounds to combat microbial biofilms
- Abstract
- 5.1 Introduction
- 5.2 Terpenes
- 5.3 Flavonoids
- 5.4 Alkaloids
- 5.5 Conclusions
- References
- 6. Vaginal microbiota biofilm in pregnancy and birth outcome: function and prospects
- Abstract
- 6.1 Introduction
- 6.2 Vaginal microbiota profile and dysbiosis during pregnancy
- 6.3 Vaginal microbiota dysbiosis and biofilm formation during pregnancy
- 6.4 Vaginal microbiota biofilm formation during pregnancy and birth outcome
- 6.5 Therapeutic insight of beneficial against pathogenic vaginal microbiota biofilm
- 6.6 Conclusion and future prospective
- Author contributions
- Acknowledgments
- Conflict of interest
- References
- 7. Microbial biofilms and their role in acute and chronic pathogenesis
- Abstract
- 7.1 Introduction to biofilm: a microbial life on surface
- 7.2 Historical perspective of biofilm
- 7.3 Biofilm and its structural component
- 7.4 Biofilm mode of growth of bacteria
- 7.5 Role of biofilms in human health
- 7.6 Microbiome and biofilm formation in lungs
- 7.7 Role of biofilms in respiratory tract and acute and chronic pathogenesis
- 7.8 Control of biofilms in respiratory infection
- 7.9 Conclusion
- References
- 8. Surface modification: strategies to prevent microbial growth on medical implants
- Abstract
- 8.1 Introduction
- 8.2 Understanding microbial growth on medical implants
- 8.3 Inhibition of microbial adhesion to device surfaces
- 8.4 Promoting microbial killing within an established biofilm
- 8.5 Physical surface modification
- 8.6 Nanopatterning
- 8.7 Surface chemical modifications
- 8.8 Conclusion and future prospective
- Acknowledgment
- References
- 9. Microbial biofilms and the skin microbiome
- Abstract
- 9.1 Introduction
- 9.2 Microbial biofilm and skin disease
- 9.3 Skin burn infection
- 9.4 Pressure ulcers
- 9.5 Conclusion
- References
- 10. Cell-to-cell interaction and cell signaling in biofilm formation
- Abstract
- 10.1 Introduction
- 10.2 Relevance and risk of biofilm
- 10.3 Factors associated with biofilm formations
- 10.4 Mechanism of biofilm formation and cell-to-cell interaction
- 10.5 Relevance and risk of biofilm
- 10.6 Factors associated with biofilm formation
- 10.7 Cell-to-cell signaling and signal interception
- 10.8 Conclusions and future prospective
- References
- 11. A concise review on genes involved in biofilm-related disease and differential gene expression in medical-related biofilms
- Abstract
- 11.1 Introduction
- 11.2 Genes involved in biofilm formation
- 11.3 Differential gene expression in pathogenic biofilms
- 11.4 Genes involved in pathogenic biofilms
- 11.5 Future perspectives
- References
- 12. Next-generation sequencing: role in microbial biofilm study
- Abstract
- 12.1 Introduction
- 12.2 Next-generation sequencing
- 12.3 Next-generation sequencing to study biofilms
- 12.4 Conclusion and future perspective
- References
- 13. Electrical signaling in growth dynamics of microbial biofilms
- Abstract
- 13.1 Introduction
- 13.2 Effectiveness of communication ensured survival
- 13.3 Communication is crucial for the evolution of complex life
- 13.4 Efficient communication forms the basis of biofilm evolution
- 13.5 Chemical signaling in microbes: quorum sensing
- 13.6 Electrical signaling in microbial biofilms
- 13.7 Summary
- References
- Index
- No. of pages: 350
- Language: English
- Edition: 1
- Published: April 10, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443192524
- eBook ISBN: 9780443192531
MY
Mukesh Kumar Yadav
Dr. Mukesh Kumar Yadav, is working as an Associate Professor at the Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India. He has more than 15 years of research experience in the field of microbiology in general and microbial biofilms, host-pathogen interaction and endophytes in particular. In his laboratory, Dr. Yadav’s is working on microbial biofilms, antimicrobial resistance, pathogenesis and identification of novel pathways for the development of new antimicrobial/antibiofilm compounds. Dr. Yadav has published more than 74 research articles and received research grants from various funding agencies like, NRF Korea, Indian Council of Medical Research (ICMR), Department of Science and Technology (DST), Department of Biotechnology (DBT) and University Grant Commission (UGC).
Affiliations and expertise
Associate Professor, Department of Microbiology, Central University of Punjab, Bathinda, Punjab, IndiaJS
Jae Jun Song
Prof. Jae Jun Song is a Professor at Korea University College of medicine Seoul, South Korea. Prof. Song is clinical professional and has more than 15 years of research experience. He has published more than 80 research papers in peer-reviewed journals and has completed many research grants related to microbial biofilms
Affiliations and expertise
Professor, Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, South KoreaJV
Jorge E. Vidal
Dr. Jorge E. Vidal is an Associate Professor in the Department of Cell and Molecular Biology and a member of the Center for Immunology and Microbial Research at the University of Mississippi Medical Center. In his research laboratory, Dr. Vidal studies the molecular mechanisms of bacterial pathogenesis, biofilm formation, and the mechanisms leading to the acquisition of antibiotic resistance. Dr. Vidal has published more than 100 research papers and has received several research grants from the NIH, BMGF, Pfizer, and other agencies.
Affiliations and expertise
Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, USARead Microbial Biofilms on ScienceDirect