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Elsevier

Academic Press

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1st Edition
    • Luca Saba + 1 more
    • English
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Thermal System Design and Simulation

    • 2nd Edition
    • P.L. Dhar + 1 more
    • English
    Thermal System Design and Simulation, Second Edition covers the fundamental analyses of thermal energy systems that enable users to effectively formulate their own simulation and optimal design procedures. It provides step-by-step guidance on how to mathematically formulate objective functions and design constraints and develop strategies to solve them to obtain optimal solutions with minimal computational effort. It uniquely illustrates the methodology of combining information flow diagrams to simplify system simulation procedures needed in optimal design. Expanded and updated for currency, the book includes case studies and a comprehensive presentation on the dynamics of thermal systems and control systems needed to ensure safe operations.Designed to give readers the hands-on skills needed to develop their own customized software for simulating and designing thermal systems, this book is useful for anyone interested in obtaining advanced knowledge of thermal system analysis and design.

  • Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery

    • 1st Edition
    • Mithun Rudrapal + 1 more
    • English
    Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery is an essential guide that bridges the latest advances in molecular and cellular biology to revolutionize drug discovery. The book explores a wide range of tools and techniques and their applications in drug discovery, including genetic engineering, gene therapy, regenerative medicine, developmental biology, molecular diagnostics, biomarkers, RNA therapeutics, molecular immunology, and vaccine development. The book also considers multi-omics approaches, biophysical methods, epigenetics and epigenomics, biomedical engineering, nanotechnology, artificial intelligence, bioinformatics, structural and computational approaches, and more.This comprehensive volume covers critical domains such as transcriptomics, proteomics, genomics, genetics, and cell signaling pathways, providing an in-depth understanding of their pivotal roles in drug development. It is an invaluable reference for researchers and advanced students working in these areas across molecular biology, biochemistry, pharmacology, biotechnology, and related fields.

  • AI and Precision Oncology

    Innovations in Diagnosis and Drug Development
    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    AI and Precision Oncology: Innovations in Diagnosis and Drug Development examines the transformative role of artificial intelligence and machine learning in oncology. The book addresses the urgent need for early cancer diagnosis and effective therapeutic treatments, highlighting how technological advancements enable rapid analysis of large datasets to enhance patient outcomes. The content explores clinical applications of next-generation sequencing (NGS) integrated with AI technologies, covering risk prediction, disease detection, biomarker identification, and therapeutic target discovery. The book emphasizes the importance of bioinformatics tools in analyzing NGS data and showcases AI-powered applications that improve cancer diagnosis and prognostication.For the academic audience, this book provides valuable insights into the latest advancements in AI and precision oncology. It equips researchers and clinicians with knowledge on personalized treatment strategies and recent clinical studies, ultimately enhancing understanding of how AI can revolutionize cancer care and improve patient management.

  • Cranial Nerve Compression Syndromes

    A Multidisciplinary Guide to Management
    • 1st Edition
    • Florian Roser + 1 more
    • English
    Cranial Nerve Compression Syndromes: A Multidisciplinary Guide to Management is a comprehensive volume exploring the entire pathophysiology of cranial nerve pathologies, from diagnosis to treatment options. Following a multidisciplinary approach, this volume integrates perspectives from neurosurgery, neurology, radiology, and pain management from experts in the field. An ideal resource for clinicians and researchers, this volume discusses the latest research on multi-modality, collaborative, and cutting-edge treatment options, with advanced surgical techniques, including microvascular decompression and endoscopic procedures with clear guidance.

  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1st Edition
    • Anand Krishnan + 3 more
    • English
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 89
    • English
    Advances in Microbial Physiology, Volume 89 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Catalytic Methods in Flow Chemistry: Part B

    • 1st Edition
    • Volume 78
    • English
    Catalytic Methods in Flow Chemistry: Part B, Volume 78 in the Advances in Catalysis series, highlights recent breakthroughs in catalytic methods under continuous‐flow conditions. This new volume presents chapters written by an international board of authors and explores cutting-edge strategies for enabling sustainable, scalable chemical synthesis. Topics include technological innovations that enhance efficiency and selectivity in continuous flow systems, the integration of biocatalysts for greener processes, and the development of streamlined approaches for active pharmaceutical ingredient (API) synthesis. Together, these contributions provide researchers and industrial practitioners with a comprehensive overview of advances that are shaping the future of flow chemistry and catalysis.

  • Modern Bioinformatics

    From Molecular Insights to Biomedical Innovation
    • 1st Edition
    • Kolla Bhanu Prakash + 2 more
    • English
    Modern Bioinformatics: From Molecular Insights to Biomedical Innovation explores the rapidly advancing field of bioinformatics, addressing a critical gap in current literature by integrating quantum biology and quantum biosensors with computational bioinformatics. The book offers a thorough exploration of bioinformatics from foundational concepts to translational applications. It begins with molecular structures of proteins, DNA, and RNA, advancing through nano-molecular visualization and structural domain analysis. Readers gain insights into deep learning techniques like AlphaFold for protein structure prediction, AI applications in genomics, and molecular interactions critical to function. The text further covers computational methods in drug discovery, forensic bioinformatics, and molecular evolution.A unique emphasis is placed on the convergence of nanotechnology and quantum innovations in molecular diagnostics and biosensing, including quantum biosensors and quantum computing applications. The final sections focus on computational strategies for drug target identification, biomarker discovery, and clinical trial analysis, providing a holistic view of modern bioinformatics workflows. This book is an indispensable reference for advanced researchers, graduate students, and professionals in bioinformatics, molecular biology, and biomedical engineering seeking to integrate quantum computing and nanotechnology into their work.

  • Pharmaceutical Hot Melt Extrusion

    From Materials Selection to Commercial Production
    • 1st Edition
    • Purnima D. Amin
    • English
    Pharmaceutical Hot Melt Extrusion: From Materials Selection to Commercial Production is an authoritative resource on the evolving landscape of HME technology. The book explores the core principles of formulation development, equipment design, process scaling, and regulatory considerations, providing essential knowledge for researchers and industry professionals. It emphasizes innovative, green manufacturing practices, solvent-free processes, and patient-centric delivery systems, making it a vital guide for advancing pharmaceutical and nutraceutical formulations. This reference enhances understanding of cutting-edge HME applications, supporting environmentally sustainable practices and innovative product development for both academia and industry.It equips formulation scientists, R&D professionals, and students with the knowledge to accelerate research, improve efficiency, and translate laboratory innovations into market-ready solutions.

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