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Academic Press

    • Vector Borne Diseases

      • 1st Edition
      • Volume 58
      • English
      Vector Borne Diseases, Volume 58 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting written by an international board of authors. Chapters in this new release cover Methods for Isolation and Characterization of Arthropod Hemocytes, Tick-to-Host Transmission of B. burgdorferi: In Vitro and In Vivo Methodologies, Decoding the Zika Virus outbreak and Infection Dynamics, Visual and molecular methods for studying pathogen persistence in flea vectors, Lipidomic Analysis of Virus-infected Cells, and Implementation of the Neutropenic Thigh Infection Murine Model with Francsiella tularensis for Development of New Antibacterials.

    • Profiles of Drug Substances, Excipients, and Related Methodology

      • 1st Edition
      • Volume 51
      • English
      Profiles of Drug Substances, Excipients, and Related Methodology, Volume 51 provides comprehensive profiles of four pharmaceutical compounds: Vortioxetine, Rosuvastatin Calcium, Perindopril, and Ferulic Acid. In addition, it includes a review article concerning Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases. Chapters in this new release include Vortioxetine: A Comprehensive Profile, Rosuvastatin Calcium: A Comprehensive Profile, Ferulic Acid: A Comprehensive Profile, Perindopril: A Comprehensive Profile, Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases, Kinetic Exclusion Assay Technology: Theory, Experimental Aspects, and Applications in Concentration Measurements Across Diverse Fields, and more.No other book series provides this essential information as promptly and pertinently. Sections provide review articles and database compilations categorized into five primary domains: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Pertaining to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.

    • The Organic Chemistry of Drug Design and Drug Action

      • 4th Edition
      • Richard B. Silverman + 2 more
      • English
      The Organic Chemistry of Drug Design and Drug Action, Fourth Edition presents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action. The book's coverage allows readers to extrapolate core principles and mechanisms to many related classes of drug molecules. It reflects the significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while also including significant changes in format and coverage.It is designed for undergraduate and graduate students in chemistry who are studying medicinal chemistry or pharmaceutical chemistry. Users, including research chemists and biochemists working in pharmaceutical and biotechnology industries will find this update to be useful in their daily work.

    • Protein Immobilization on Nanomaterials

      • 1st Edition
      • José Cleiton Sousa dos Santos
      • English
      Protein Immobilization on Nanomaterials explores advanced technologies and methodologies for immobilizing proteins on nanomaterial surfaces, highlighting their innovative applications in biotechnology, medicine, and materials engineering. Sections delve into various methods of protein immobilization, including physical adsorption, covalent binding, and encapsulation, providing detailed explanations and practical examples. The book also covers the characterization of protein-nanomaterial conjugates using advanced analytical techniques such as spectroscopy and microscopy. With contributions from leading experts, the book presents colorful figures and practical examples to facilitate understanding of complex concepts. It is an ideal resource for researchers and practitioners on the latest techniques and advances.Key topics covered include the use of protein-nanomaterial conjugates in biosensors, diagnostic devices, drug delivery systems, and environmental monitoring. Academic researchers in biotechnology and nanotechnology, biochemical engineers, medical device developers, and scientists specializing in nanomaterials and surface engineering will find this a valuable resource. It will also be important for postgraduate students and professionals in the health technology sector, providing the knowledge and tools needed to advance their work and inspire multidisciplinary innovation.

    • Protein Kinase Inhibitors

      The Promise of Natural Products in Cancer Therapeutics
      • 1st Edition
      • Md. Imtaiyaz Hassan + 1 more
      • English
      Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

    • Cell Death Part A

      • 1st Edition
      • Volume 205
      • English
      This comprehensive volume explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. The book brings together leading experts to discuss both established and emerging approaches for studying cell death, with a strong emphasis on practical laboratory techniques and their applications in disease research and drug discovery.

    • Sustainable Microalgal Biorefinery

      • 1st Edition
      • Naim Rashid + 1 more
      • English
      Sustainable Microalgal Biorefinery, the latest release in Elsevier's Developments in Microbial Cell Factories: From Design to Commercial Production series, provides an overview of microalgae at the cellular level, along with their potential uses across a range of industries. Beginning with an introduction to microalgae biorefinery systems and the latest research and limitations, the book delves into the fundamental aspects of microalgae and their potential applications, such as biofuel production, water treatment, bioplastics production, carbon capture, aquaculture feed, and high-value bioproducts, including food, biotechnology, and pharmaceuticals. Photobioreactors design for microalgae are also covered, as well as genetic modifications to achieve desired bio-products. The book also focuses on assessing the social, environmental, and economic sustainability of microalgae technologies and how microalgae contributes to achieving UN SDG goals. This latest volume provides researchers with valuable insights into the transformation of traditional algal research and the recent trends of resource recovery and integrated technology that can be utilized to enhance sustainability and commercialization potential of microalgae.

    • Apolipoprotein E in Health and Disease

      Unravelling its Intricate Roles
      • 1st Edition
      • Dileep Kumar + 2 more
      • English
      Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

    • Pediatric Deep Brain Stimulation

      • 1st Edition
      • George M. Ibrahim + 1 more
      • English
      Pediatric Deep Brain Stimulation explores the significance and diverse treatment options using DBS for childhood disorders. The text is structured into four key sections, the first of which provides an extensive overview of a pediatric DBS program, including essential aspects like imaging techniques, potential complications, and ethical considerations. This initial section lays the foundation for understanding the transformative impact of DBS on young patients' lives. The subsequent sections delve into specific applications of DBS. The second section focuses on treating various movement disorders such as dystonia and non-dystonic movement disorders. The third section highlights neuromodulation techniques for managing childhood epilepsy.Finally, the book addresses the use of DBS in treating other pediatric neurodevelopmental disorders. Edited by leading pediatric neurosurgeons, this resource stands as the definitive guide to pediatric brain stimulation, offering invaluable insights for clinicians and researchers alike.

    • The Microbiome and Cancer Treatment

      Overcoming Resistance and Enhancing Efficacy
      • 1st Edition
      • Sadhna Aggarwal + 3 more
      • English
      “The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy” delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance. This knowledge can guide the development of innovative strategies to counteract drug resistance. The book also addresses the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters fosters interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. The audience can benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

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Butterworth-Heinemann

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