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Elsevier

Academic Press

  • Hydrophilic-Lipophilic Deviation in Formulation Science and Technology

    Principles, Methods, and Applications of HLD
    • 1st Edition
    • Jean-Louis Salager + 2 more
    • English
    Hydrophilic-Lipophil... Deviation in Formulation Science and Technology: Principles, Methods, and Applications of HLD offers an in-depth examination of the Hydrophilic-Lipophil... Deviation (HLD) concept as a foundational, quantifiable optimization tool in the formulation science of surfactant, oil, and water systems. It brings together contributions from leading experts to cover the historical development of formulation concepts in the past hundred years, from the Bancroft rule, Winsor R, Beerbover CER, Israelachvili intermolecular packing, Griffin HLB and Shinoda PIT through to the advanced HLD multivariable framework, as a way to select an appropriate multi surrogate expression. It provides a deep dive into critical topics such as surfactant and oil characterization, macro-/micro-/nano-e... formulation and properties, particularly interfacial rheology. It also deals with practical applications such as detergency, enhanced oil recovery (EOR), demulsification, asphaltic emulsions, food processing and distribution, cosmetics and medical preparations, and other consumer or industrial products. Each chapter combines theoretical foundations with practical insights, including mistakes and confusions, supported by case studies and recent research findings. The structured approach facilitates a comprehensive understanding the meaning of HLD and its impact on formulation science in various sectors including academia and industry.This book will address the challenges faced by practitioners in designing and optimizing formulations, ultimately enhancing product performance in interfacial tension, solubilization, time stability and fluid properties. Hydrophilic-Lipophil... Deviation in Formulation Science and Technology: Principles, Methods, and Applications of HLD is written primarily for advanced researchers, scientists, and engineers specializing in formulation science, colloid and interface science, surfactant chemistry, and chemical engineering.

  • Herbals and Their Antioxidant Effects on Human Health

    • 1st Edition
    • Süleyman Kaplan
    • English
    Herbals and their Effects on Human Health provides a comprehensive exploration of the diverse bioactive components found in medicinal plants and their relevance to human health. Divided into three distinct sections, beginning with a thorough examination of bioactive components and their health benefits, readers will discover the intricacies of traditional practices such as Ayurveda, the role of phytotherapy in managing metabolic disorders, and the therapeutic potential of antioxidants in various health contexts, including skin health and cardiovascular disease. The book further enhances its scientific rigor by including light and electron microscopic images that illustrate tissue and organ structures affected by herbal interventions. Subsequent sections focus on bioactive foods, highlighting their therapeutic effects through in-depth discussions on specific herbals and plants such as garlic, curcumin, garcinia kola and blueberries. This section not only examines their protective roles in conditions like chronic inflammation and diabetes but also addresses lesser-known foods and their health-promoting properties. The final section highlights the mechanisms of action of these compounds, examining their impact on biological systems and their neuroprotective effects.Herbals and their Effects on Human Health is an essential resource for food scientists, physicians, biomedical researchers, pharmacologists, and nutritionists seeking to deepen their understanding of how herbal and bioactive components influence health and wellness.

  • Neuroinflammation and Biomarker Discovery

    From Mechanisms to Clinical Application
    • 1st Edition
    • Arun Kumar Singh + 1 more
    • English
    Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

  • Precision Care in Gastroesophageal Reflux Disease

    Using Pathophysiology and Clinical Insights towards a Personalized Approach
    • 1st Edition
    • Walter W. Chan + 1 more
    • English
    Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.

  • Computer Vision

    Principles, Algorithms, Applications, Learning
    • 6th Edition
    • E. R. Davies + 1 more
    • English
    Computer Vision: Principles, Algorithms, Applications, Learning, Sixth Edition clearly and systematically presents the basic methodology of computer vision, covering the essential elements of the theory while emphasizing algorithmic and practical design constraints. This new sixth edition has brought in more of the concepts and applications of computer vision, making it a very comprehensive and up-to-date text suitable for undergraduate and graduate students, researchers and R&D engineers working in this vibrant subject.

  • Predictive Digital Twins

    Foundations and Applications
    • 1st Edition
    • Agus Hasan
    • English
    Predictive Digital Twins: Foundations and Applications addresses the theoretical foundations, practical applications, and emerging trends associated with predictive digital twins. Specifically focusing on predictive capabilities, digital twins designated for this purpose are commonly known as predictive digital twins. Despite the growing recognition of their importance, discussions surrounding predictive digital twins remain fragmented and lacking a comprehensive resource. This gap becomes particularly pronounced in the academic world, where, as a university professor teaching a master's program course in digital twins, there arises a pressing need for a dedicated reference book to furnish students with a structured and in-depth exploration of predictive digital twins.The book fills the existing void in literature and academia, providing students, researchers, and practitioners with a valuable resource to enhance their understanding of this cutting-edge concept. The digital twin concept stands as a pivotal facilitator in the ongoing Industry 4.0 revolution, with one of its most significant advantages lying in its capacity to offer precise predictions.

  • Clinical Cancer Genomic Medicine

    • 1st Edition
    • Eamonn Maher + 3 more
    • English
    Clinical Cancer Genomic Medicine: Translational and Applied covers all major aspects of genetics and genomics in cancer development, diagnosis, and management, and their use in the clinical setting. The book explores not only the genetic basis of cancer, but also the role genomics plays in understanding the molecular basis of disease and how it can aid in diagnosis and treatment. Sections discuss the basics of oncogenomic and emerging technologies and specific cancer types, such as breast, gastrointestinal, ocular, skin, and pediatric. The book also includes knowledge on diagnostic cancer genomic techniques, surgical approaches, and ethical, legal, and social implications.This is a valuable resource for oncologists, clinicians, researchers, healthcare workers, and members of the biomedical field who need to understand more about the benefits of genetics and genomics for cancer and their applications in the clinical setting.

  • Brain Pathologies and Disorders

    • 1st Edition
    • Ayman S. El-Baz + 1 more
    • English
    Neural engineering is an emerging and fast-moving interdisciplinary research area that combines engineering with (a) electronic and photonic technologies, (b) computer science, (c) physics, (d) chemistry, (e) mathematics, and (f) cellular, molecular, cognitive, and behavioral neuroscience. This helps us understand the organizational principles and underlying mechanisms of the biology of neural systems and to further to study the behavioral dynamics and complexity of neural systems in nature.The field of neural engineering deals with many aspects of basic and clinical problems associated with neural dysfunction, including (i) the representation of sensory and motor information, (ii) electrical stimulation of the neuromuscular system to control muscle activation and movement, (iii) the analysis and visualization of complex neural systems at multiscale from the single cell to system levels to understand the underlying mechanisms, (iv) development of novel electronic and photonic devices and techniques for experimental probing, the neural simulation studies, (v) the design and development of human–machine interface systems and artificial vision sensors, and (vi) neural prosthesis to restore and enhance the impaired sensory and motor systems and functions.To highlight this emerging discipline, Dr. Ayman El-Baz and Dr. Jasjit Suri have developed Advances in Neural Engineering, covering the broad spectrum of neural engineering subfields and applications. This Series includes 7 volumes in the following order: Volume 1: Signal Processing Strategies, Volume 2: Brain-Computer Interfaces, Volume 3: Diagnostic Imaging Systems, Volume 4: Brain Pathologies and Disorders, Volume 5: Computing and Data Technologies, Volume 6: Advanced Brain Imaging Techniques and Volume 7: Neural Science Ethics.Volume 4 provides a comprehensive review of brain pathologies and disorders, including Parkinson’s Disease, Alzheimer’s Disease, Attention-Deficit/Hy... Disorder, and Tourette’s Syndrome. The authors discuss existing challenges in the domain of diagnosis, detection, analysis, treatment modalities, as well as possible research directions.

  • RNA-Binding Proteins Part B

    • 1st Edition
    • Volume 744
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Rare and Complex Liver Diseases

    • 1st Edition
    • Ansgar Wilhelm Lohse + 2 more
    • English
    Rare and Complex Liver Diseases is a comprehensive guide that fills a critical gap in the literature, providing up-to-date, practical advice. The book is organized into distinct sections, each dedicated to a specific category of liver diseases. Topics covered include Autoimmune Liver Diseases such as Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC); Cholestatic Liver Diseases including Biliary Atresia and Alagille Syndrome; Vascular Liver Diseases like Budd-Chiari Syndrome and Non-cirrhotic Portal Hypertension; Metabolic Liver Diseases such as Wilson Disease and Alpha-1 Antitrypsin Deficiency; Structural Liver Diseases including Polycystic Liver Disease; and Rare Liver Tumors like Cholangiocarcinoma and Hemangioendothelioma... chapters cover Liver Disease in Pregnancy and delve into Quality of Life issues, offering evidence-based insights and practical strategies for improving patient well-being. This book serves as an indispensable resource for gastroenterologists, hepatologists, internists, and researchers specializing in liver diseases. It equips these professionals with the knowledge and practical advice necessary to improve patient outcomes and advance their field of study.

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