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Academic Press

    • Cerebellum Development and Disease

      • 1st Edition
      • Volume 167
      • English
      Cerebellum Development and Disease offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

    • Structural Study of Amyloid-β

      • 1st Edition
      • Volume 729
      • English
      Structural Study of Amyloid-β, Volume 729 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics such as the Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis, Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools, Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET, Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan, Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR, and much more.Additional chapters cover the Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization, Characterizations of the beta-amyloid-membran... interaction intermediates, Time-resolved solid-state NMR studies of oligomer formation, Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy, Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation, Two-dimensional FT-IR methods on amyloid aggregation and folding pathways, and much more.

    • Advances in Imaging and Electron Physics

      • 1st Edition
      • Volume 237
      • English
      Advances in Imaging and Electron Physics, Volume 237 merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy.

    • Sustainable Cropping Systems Under a Changing Climate

      • 1st Edition
      • Mukhtar Ahmed
      • English
      Sustainable Cropping Systems Under a Changing Climate explores how climate change is reshaping agriculture and highlights the urgent need for resilient, adaptive, and sustainable farming practices. As extreme weather, rising temperatures, and resource pressures threaten food security, this volume offers practical pathways to transform agricultural systems.Bringing together leading research, real-world case studies, and innovative strategies, this book addresses vulnerabilities and opportunities in modern farming. It covers sustainability principles, climate-smart practices, and the roles of soil health, biodiversity, conservation agriculture, organic farming, agroforestry, regenerative approaches, and plant–microbe interactions in enhancing resilience. Special focus is given to intensive systems such as rice–wheat and rainfed agriculture, particularly in the Global South.With an interdisciplinary approach and emphasis on both scientific evidence and practical application, this volume bridges a critical gap by supporting informed decision-making at farm, institutional, and policy levels. It is a timely resource for researchers, agronomists, extension professionals, and others seeking to future-proof agriculture through nature-based and technological solutions for climate adaptation and mitigation.

    • Plant Proteins

      Nutritional Aspects and Processing Applications
      • 1st Edition
      • Nisar Ahmad Mir + 1 more
      • English
      Plant Proteins: Nutritional Aspects and Processing Applications covers various methods used to extract and purify plant proteins for nutrition, health, and new product development. The book identifies techniques and modifications such as fermentation, radiation, and ball-milling to characterize plant protein structure and functionality. Readers will learn how each method serves a different purpose in enhancing flavor, texture, and/or shelf-life. A special focus on plant-based meat is discussed, along with insights on how plant-based proteins effect digestive wellness and the microbiome. Additional sections address the nano-reduction of plant-based proteins and their role in the delivery of different bioactive compounds and health benefits.

    • Innovations in the Blue Economy

      Sustainable Practices in Marine Macro- and Microalgae Cultivation
      • 1st Edition
      • José Carlos Magalhães Pires
      • English
      Innovations in the Blue Economy: Sustainable Practices in Marine Macro- and Microalgae Cultivation explores the latest technologies, advancements, and ongoing research surrounding the sustainable cultivation of microalgae and seaweed. Cultivation strategies, challenges, applications, products, and regulatory considerations are covered through an interdisciplinary lens to provide readers with a holistic understanding. Written by a globally diverse network of experts, the book is systematically structured to be accessible to readers across multiple sectors. Chapters describe the biology, diversity, and vital ecological roles of various microalgal and seaweed species and explore differing cultivation systems, emphasizing the critical aspects of site selection and ecosystem compatibility. Cultivation strategies are also described and illustrated through applied case studies that showcase successful large-scale cultivation initiatives. Final chapters consider regulatory landscapes and multifaceted hurdles to sustainable industry scale-up and provide innovative solutions and research gaps for industry consideration. This is an essential read for algal aquaculturists, bioengineers, and students of marine biology and biotechnology.

    • Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

      • 1st Edition
      • Ramesh Kumar Ahirwar + 4 more
      • English
      Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control offers a comprehensive exploration of advanced methods in plant metabolomics, along with their integration in industrial applications across various sectors. The book delves into a range of methodologies, including metabolic engineering strategies, metabolite imaging techniques, nuclear magnetic resonance (NMR) for plant metabolite analysis, microfluidics for metabolite profiling, computational methods, and bioinformatics tools. It also explores plant metabolomics for crop improvement, pharmaceutical development, archaeological examinations, cosmetic formulations, and food quality, with case studies featured throughout the book to showcase real-world applications and scenarios. As the demand for natural products and plant-derived therapeutics continues to rise, there is a need for reliable and effective methods to identify, quantify, and optimize the bioactive compounds present in plants. This book provides a comprehensive guide to the latest advances in this field while also delivering a multidisciplinary overview of the wide-ranging impact plant metabolites have across a variety of applications. Researchers working with plant metabolites across molecular and cellular biology, pharmaceutical science, biotechnology, biochemistry and plant science will benefit from this book. Additionally, it will be of interest to specialists working across relevant industries, such as pharmaceuticals, nutraceuticals, cosmetics and agriculture.

    • Explainable AI in Clinical Practice

      Methods, Applications, and Implementation
      • 1st Edition
      • Arvind Panwar + 4 more
      • English
      Explainable AI in Clinical Practice: Methods, Applications, and Implementation bridges the gap between artificial intelligence capabilities and their practical implementation in healthcare. The book explores applications of explainable AI in diagnostic support and treatment planning, offering insights into making AI systems interpretable and accountable. Through real-world case studies and ethical frameworks, readers learn to transform opaque AI systems into tools that enhance clinical practice while maintaining high patient care standards. This volume unites leading experts to provide a comprehensive framework for implementing explainable AI, ensuring that AI-driven decisions are transparent, trustworthy, and clinically sound. Targeted solutions in the book cater to diverse stakeholders in the healthcare AI ecosystem. Healthcare professionals will gain confidence in integrating AI tools, while technical teams will receive implementation guidelines. This book is essential for anyone seeking to responsibly and effectively navigate the complexities of AI in healthcare.

    • The Gut Microbiome in Precision Medicine

      From Research to Clinical Practice
      • 1st Edition
      • S Rehan Ahmad
      • English
      The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastrointestinal conditions such as inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. It covers how understanding and analyzing the gut microbiome can lead to personalized treatments, dietary plans, and precision medicine approaches in gastroenterology. Chapters explore multi-omics integration, examining complex techniques for gut microbiome profiling, including genomics, transcriptomics, proteomics, and metabolomics. Users will find updates on microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition that highlight practical applications in gastrointestinal disease management. Real-world examples and case studies discuss strategies for overcoming barriers to implementing microbiome analysis. Additionally, it addresses the challenges and opportunities of implementing microbiome analysis in clinical practice, with a special emphasis on its implications for developing countries. Finally, the book covers emerging technologies in microbiome research and their applications in gastroenterology, emphasizing future directions and research priorities.

    • Chalcones

      From Drug Discovery to Pharmaceutical Applications
      • 1st Edition
      • Simone Carradori + 2 more
      • English
      Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

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Butterworth-Heinemann

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