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Elsevier

Academic Press

  • Mannose Binding Lectin Associated Serine Proteases

    Structure, Function and Therapeutic Implications
    • 1st Edition
    • Krishnan Hajela
    • English
    Mannose Binding Lectin Associated Serine Proteases: Structure, Function and Therapeutic Implications provides a comprehensive overview of MASP-1, MASP-2, and MASP-3, highlighting their roles in immune defense, disease mechanisms, and therapeutic intervention. This book covers the molecular structure and catalytic mechanisms of these key serine proteases, emphasizing their involvement in the lectin pathway of complement activation as well as their emerging functions in coagulation and bradykinin pathways. Chapters detail the biology of animal lectins and collections, classical and alternative complement pathways, and specific biochemical activities of MASP-1, MASP-2, and MASP-3.Readers will find in-depth discussions on the clinical significance of MASP gene polymorphisms and serum levels, and more. Special focus is given to the application of MASP-2 inhibitors in the management of complications such as hematopoietic stem-cell transplantation-asso... thrombotic microangiopathy (HSCT-TMA). This book is an essential resource for researchers in immunology, biochemistry, and molecular medicine, as well as clinicians seeking to advance their understanding of complement biology and the therapeutic potential of targeting the lectin pathway.

  • Sustainable Livestock Nutrition through Alternative Feed Ingredients

    • 1st Edition
    • Prabhat Khanal + 2 more
    • English
    Sustainable Livestock Nutrition through Alternative Feed Ingredients synthesizes the latest knowledge on alternative feed ingredients in livestock diets. With the use of sustainable, low-waste, and circular feed ingredients, livestock can gain essential key nutrients while reducing their environmental impact. Through meticulous research and practical insights, the book explores alternative proteins and nutritional sources for a variety of animals. Cutting-edge, low-impact ingredients, including insects, algae, microalgae, seaweed, and freshwater plants are covered and compared. Written and edited by an international team of experts, and with a focus on enhancing animal health and welfare while minimizing environmental impact, this book serves as a vital resource for researchers, farmers, students, and policymakers.

  • Biomechanics of the Heart

    From Model to Patient
    • 1st Edition
    • Patrick Clarysse + 3 more
    • English
    Biomechanics of the Heart: From Model to Patient provides readers with a comprehensive overview of the modeling and assessment of the heart’s biomechanics. The book addresses topics such as the physiology of normal and diseased hearts, cardiovascular imaging, modeling of myocardial tissue in the passive and active states, as well as state-of-the-art approaches for patient specific modeling of the heart’s mechanical function. This is all augmented by case studies and examples of exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases. Readers are introduced to modeling of the heart’s anatomical and muscular structure, a review of imaging techniques to analyze the geometry, content and dynamics of the heart, as well as an in-depth look at the biomechanical properties of normal and diseased hearts. Finally, chapters cover modeling cardiac passive and contractile mechanics, biomechanical finite element simulations of the heart, patient-specific modeling of the heart and circulatory system, as well as the exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 2nd Edition
    • Caleb M. Pearson + 2 more
    • English
    The second edition of Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice offers an in-depth review of the critical role neuropsychology plays in neurosurgical settings. This comprehensive resource covers essential preoperative techniques, including advanced functional neuroimaging methods such as fMRI and connectivity-based imaging, alongside traditional approaches like neurocognitive testing and the Wada procedure. This book highlights the significant contributions of neuropsychologists to the neurosurgical team, emphasizing their value in managing diverse patient populations, from candidates for Deep Brain Stimulation to those undergoing adult and pediatric epilepsy surgeries and neuro-oncology interventions. New chapters in this edition address contemporary topics such as the cognitive impact of epilepsy and epilepsy surgery, concussion, neuroplasticity, and the future role of artificial intelligence in neurosurgery. By updating existing content and incorporating fresh insights, this book serves as an essential guide for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, and general neurologists who wish to enhance their understanding of neuropsychology's application in both preoperative and postoperative care.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Translational Insights in Regenerative Medicine

    • 1st Edition
    • Volume 228
    • English
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Food Authentication and Future Challenges

    Ensuring Transparency in the Global Food Supply
    • 1st Edition
    • Shahzad Zafar Iqbal + 1 more
    • English
    Food Authentication and Future Challenges: Ensuring Transparency in the Global Food Supply explores the vital role of verifying food origin, content, and quality to prevent fraud, ensure safety, and meet regulatory standards. As globalization, climate change, and shifting consumer demands increase the complexity of food integrity, this book offers essential insights into current methods and emerging technologies for safeguarding our food supply. The book is divided into clear sections, covering foundational concepts, advanced identification techniques like chromatography, spectroscopy, DNA, and sensor-based methods, as well as specific challenges related to seafood, meat, honey, oils, herbs, and GMOs. It also highlights innovative solutions such as AI, machine learning, NGS, and CRISPR, and discusses key issues like climate impacts, ethical concerns, and policy enforcement. By combining scientific advances with future perspectives, this book provides a comprehensive resource for researchers, industry professionals, and policymakers committed to protecting food integrity in a rapidly changing world.

  • Food and Diets in Health and Disease

    Decoding the Impact of Food Constituents on Well-Being
    • 1st Edition
    • Anil Kumar Khumra + 1 more
    • English
    Food and Diet in Health and Disease: Decoding the Impact of Food Constituents on Well Being examines the intricate relationship between food constituents and health outcomes, addressing a significant gap in the translation of scientific knowledge into practical dietary guidance. Organized into seven comprehensive sections, the book offers an analysis of macro and micronutrients, non-nutrient compounds, and functional constituents, with a particular focus on their disease-preventative properties. The text further explores the multifaceted roles of complex carbohydrates, proteins, lipids, and phytonutrients in promoting health, while also providing an in-depth analysis of traditional dietary frameworks, such as the Mediterranean and Ayurvedic diets, as mechanisms for disease mitigation. Targeted for food scientists and nutritionists, "Food and Diet in Health and Disease” serves as a resource that synthesizes the latest evidence-based research into actionable dietary strategies. Each chapter addresses prevalent health challenges, including the management of diabetes, obesity, the gut microbiome and mental health, while also considering the implications of food safety and public health policy.

  • Trauma Informed Care in Pediatric Acute and Critical Care Setting

    An Approach for Promoting Resilience and Recovery
    • 1st Edition
    • Trevor A. Hall + 1 more
    • English
    Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery is a groundbreaking resource addressing the urgent need for trauma-informed care (TIC) in pediatric intensive care units (PICUs) and acute care settings. Each year, countless children and their families navigate the overwhelming challenges of hospitalization due to life-threatening injuries or illnesses. This book explores the profound psychological impacts of such experiences and underscores the necessity of integrating TIC principles to foster resilience and enhance recovery. Within its pages, readers will discover a comprehensive exploration of TIC elements and principles, such as recognizing signs of psychological trauma, ensuring safety, and promoting trustworthiness and empowerment. The text examines pediatric medical traumatic stress, secondary trauma, and the importance of TIC for long-term health outcomes. Featuring contributions from a multidisciplinary team of experts, the book offers practical strategies for developing and sustaining TIC programs. It provides insights into the unique environment of pediatric acute settings, the roles of healthcare professionals, and the global landscape of healthcare systems, while also addressing essential aspects of follow-up care. Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery equips healthcare professionals with the knowledge to improve patient care, reduce professional burnout, and advance the field of pediatric acute care. With its focus on awareness, readiness, detection, management, and integration of TIC principles, this essential guide is poised to transform the experience of children, families, and healthcare teams by fostering a culture of healing and resilience.

  • Diagnosis and Management of Gastrointestinal Bleeding

    • 1st Edition
    • Xingshun Qi + 1 more
    • English
    Diagnosis and Management of Gastrointestinal Bleeding is a comprehensive reference addressing the latest advances in the diagnosis and management of gastrointestinal hemorrhage. This reference responds to the growing body of evidence accumulated in recent years, filling a critical gap where no recent comprehensive resource exists. It targets practicing gastroenterologists and researchers seeking current, evidence-based guidance. The content is systematically organized into 14 chapters covering epidemiology, causes, risk factors, diagnosis, and treatment modalities including medical, endoscopic, and vascular interventional approaches. Special chapters focus on management in children and the elderly. Each chapter is authored by leading experts, providing detailed insights into prevention, treatment, and prognostic assessment of gastrointestinal bleeding. Diagnosis and Management of Gastrointestinal Bleeding equips clinicians with practical knowledge to improve patient care and offers researchers a synthesis of innovative findings and future research directions. Its inclusion of color figures and visual aids enhances comprehension. This reference is an essential resource for those involved in the clinical and research aspects of gastrointestinal bleeding management.

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