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Elsevier

Academic Press

  • Advances in Mitochondrial Drug Delivery

    From Molecular Mechanisms to Clinical Translation
    • 1st Edition
    • Prashant Kesharwani
    • English
    Advances in Mitochondrial Drug Delivery: From Molecular Mechanisms to Clinical Translation addresses the critical need for a comprehensive resource on mitochondrial-target... drug delivery systems. As recent advancements in drug delivery systems (DDS) have shown substantial promise in treating diseases linked to mitochondrial dysfunction, there is a pressing demand for a consolidated reference that covers both the foundational aspects and the latest innovations in this field. The book's Table of Contents encompasses a wide range of topics, beginning with the fundamentals of mitochondrial biology and drug delivery, followed by various mitochondrial-target... drug delivery strategies. It further explores advanced applications of these systems in treating cancer, neurodegenerative diseases, cardiovascular conditions, and more. Additionally, the book discusses future directions, clinical translation, and regulatory challenges, ensuring a holistic view of the subject matter. Advances in Mitochondrial Drug Delivery offers significant benefits to researchers, students, and professionals in pharmaceutical sciences and nanotechnology. By integrating diverse perspectives from leading experts, the book serves as an essential resource for understanding the complexities of mitochondrial-target... therapies, thereby fostering advancements in drug delivery systems and therapeutic strategies.

  • Machine Learning and Urban Health

    Advancing Wellness through Data Analytics
    • 1st Edition
    • Deepak Kumar + 3 more
    • English
    Machine Learning and Urban Health: Advancing Wellness through Data Analytics explores how advanced data analytics and machine learning are reshaping the future of urban wellness. As cities worldwide evolve into highly interconnected, technology-driven spaces, new opportunities—and challenges—emerge for ensuring sustainable urban health. This timely volume addresses the critical question: how can we harness the power of data to improve health outcomes in complex urban environments? From predicting disease outbreaks to identifying vulnerable populations and optimizing resource allocation, this book highlights how machine learning is transforming the public health landscape.Drawing on real-world case studies and diverse datasets—including environmental sensors, population health indicators, and urban infrastructure metrics—the book provides actionable insights for researchers, policymakers, urban planners, and public health professionals. It emphasizes not only technical innovation but also the ethical and equitable use of health data to reduce disparities and enhance quality of life for all city residents.

  • Animals and Human Society

    Impacts of Animals on People and People on Animals
    • 2nd Edition
    • Colin G. Scanes + 1 more
    • English
    Animals and Human Society: Impacts of Animals on People and People on Animals, Second editon provides a solid, scientific, research-based background to advance our understanding of how animals and humans interact and impact each other. Animals and humans have had profound effects on each other throughout human history, spanning all aspects of human society from agriculture, disease, culture, religion, companionship, entertainment, environment, and more. Developed by renowned experts Colin Scanes and Clive Phillips, this second edition features a new introductory chapter covering the biological concepts necessary for technical and non-technical audiences of this book. All first edition chapters have been revised to bring readers up to date on research advancements from the last decade, and novel chapters cover animal ethics, welfare, the basis of anthrozoology, zooarchaeology, and more. Guest essays further supplement updated chapter content by providing broad interdisciplinary and geographically diverse perspectives in the field. Animals and Human Society, Second Edition is an excellent resource for academics and industry professionals requiring fundamental information on the history and biology behind human-animal interactions, as well as interested laypersons looking to augment their knowledge on the many impacts of animals in human society.

  • Medical and Health Genomics of South Asia

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

  • Anorectal Malformations

    • 1st Edition
    • Ivo de Blaauw + 2 more
    • English
    Anorectal Malformations is an essential resource for pediatric surgical specialists and caregivers, providing a comprehensive approach to the diagnosis, treatment, and follow-up of patients with anorectal malformations. This book not only covers the latest surgical techniques but also delves into the intricacies of the condition, offering structured advice from a trusted organization, ERN eUROGEN, and addressing the significant gaps in literature related to this rare disease. The handbook is meticulously organized, beginning with an introduction to the ERN eUROGEN and ARMnet networks, followed by an exploration of key topics such as anatomy, embryology, genetics, and epidemiology of anorectal malformations. It details surgical procedures, including colostomy and reconstruction techniques, as well as non-surgical treatments for common complications like constipation and incontinence. The book also emphasizes long-term outcomes, global care networks, and patient perspectives, ensuring a holistic understanding of the patient journey.Anorectal Malformations is invaluable for clinicians, researchers, and healthcare professionals, providing the necessary insights to make accurate diagnoses, perform effective surgeries, and ensure proper follow-up care. It serves as a critical reference guide for anyone involved in the care of patients with anorectal malformations, ultimately improving clinical outcomes and enhancing the quality of life for affected individuals and their families.

  • Insect Bioactives

    Innovations in Food, Feed, Pharma and Cosmetics
    • 1st Edition
    • Abdalbasit Adam Mariod + 2 more
    • English
    Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics serves as a comprehensive resource for researchers and professionals seeking to harness the power of insects as sustainable bioactive sources and beneficial health and wellness solutions. The book identifies the nutritional and chemical composition of insects, presenting them as versatile ingredients for the development of functional foods, nutraceuticals, animal feed and cosmetics. By examining how edible insects can be reared on agri-food by-products and organic waste, this volume illustrates how feeding strategies can influence their nutritional and bioactive profiles. The text also addresses potential allergenic risks and consumer behavior insights, equipping readers with strategies to promote acceptance of insect-based products in the market.Structured into eight sections, Insect Bioactives: Innovations in Food, Feed, Pharma and Cosmetics covers a wide array of topics essential for understanding insect bioactives. From the foundational overview of insect-based compounds to their applications in functional foods, animal feed, pharmaceuticals, and cosmetics, each section provides insights into the health benefits and technological innovations associated with insect bioactives. The text also discusses regulatory considerations and features case studies that showcase successful applications in various industries.

  • Cultural Dimensions of Ageism

    East Meets West Toward an Age-inclusive Society
    • 1st Edition
    • Takashi Yamashita + 1 more
    • English
    Cultural Dimensions of Ageism: East Meets West Toward an Age-Inclusive Society explores ageism in two contrasting nations—Japan and the United States—and their respective approaches to addressing it. Despite its longstanding presence, ageism remains an underrecognized form of discrimination and stereotyping. As populations age rapidly worldwide, ageism manifests with striking similarities and profound differences across cultures, significantly shaping the lives of older adults. Drawing on these cross-cultural perspectives, the book offers strategic solutions for combatting ageism in a transcultural context, providing valuable insights for building a more inclusive, respectful global society. This groundbreaking contribution integrates novel, critical cross-national insights from two distinct cultural zones: Japan, a super-aged society with the world's highest life expectancy, and the United States, an economically developed nation with demographically and culturally diverse populations. Readers will find comprehensive coverage of ageism, cross-cultural comparison, and global aging in one succinct resource. For scientists and researchers, the book offers cross-cultural observations of ageism research from East/Japan and West/North America, with reflective questions and key takeaways to facilitate engagement. Clinicians will benefit from increased knowledge about ageism in diverse global communities, enriched by case studies and personal stories that bring a human element to the research. This is an essential resource for anyone dedicated to understanding and addressing ageism in our rapidly aging world.

  • Decoding the JAK-STAT Pathway

    Emerging Insights and Clinical Applications Across Diseases
    • 1st Edition
    • Meenakshi Dhanawat + 1 more
    • English
    Decoding the JAK-STAT Pathway: Emerging Insights and Clinical Applications Across Diseases offers a comprehensive exploration of one of the most vital molecular signaling pathways in human health and immune regulation. This reference addresses the critical need for an integrated resource that connects fundamental immunological mechanisms with translational and clinical applications, particularly in autoimmune, inflammatory, and infectious diseases. The book covers the pathway’s physiological roles in cytokine signaling, immune homeostasis, and cellular communication, as well as its dysregulation in conditions such as rheumatoid arthritis, inflammatory bowel disease, neuroinflammation, and viral infections. Its chapters feature contributions from global experts, detailing recent advances in targeted therapies, including JAK inhibitors, and their potential for personalized medicine. The content is organized to highlight disease-specific roles, therapeutic strategies, and emerging research directions, making it an essential resource for immunologists, biomedical scientists, clinicians, and pharmaceutical researchers seeking an authoritative, up-to-date guide to the molecular and clinical aspects of JAK-STAT signaling. By elucidating how this pathway influences immune responses and disease progression, the book facilitates a deeper understanding of immune regulation and offers insights into novel treatment approaches, ultimately supporting advancements in immunotherapy and precision medicine across diverse patient populations worldwide.

  • A Comprehensive Guide to Surgical Oncology

    • 1st Edition
    • Aqeel Shakir Mahmood + 2 more
    • English
    A Comprehensive Guide to Surgical Oncology is an authoritative reference that meticulously covers the surgical management of various cancers. Each section delves into the latest surgical techniques, treatment protocols, and post-operative care strategies, supported by up-to-date research and clinical evidence. Enriched with detailed illustrations, case studies, and expert insights, this book is an indispensable resource for professionals and students alike. The primary purpose of this book is to provide a comprehensive, up-to-date resource that addresses the current challenges and advancements in surgical oncology. As cancer treatment evolves rapidly with continuous improvements in surgical techniques and multidisciplinary care, there is a pressing need for a new resource that synthesizes these developments into a coherent guide. This book aims to fill that gap by offering a thorough overview of the latest surgical oncology practices, thereby enhancing the knowledge and skills of its readers. This book solves several key problems for its readers by bridging the gap between rapidly advancing research and clinical practice, ensuring access to the latest information. It consolidates a vast amount of information into one comprehensive volume, saving readers the time and effort of consulting multiple sources. Providing practical guidance on the surgical management of a wide range of cancers, it helps practitioners make informed decisions in clinical settings. For students and trainees, it serves as a valuable educational tool that covers both foundational knowledge and advanced concepts in surgical oncology, offering multidisciplinary insights that foster a better understanding of the collaborative efforts required in cancer treatment.

  • Physiology, Medicine, and Health Sciences

    Catalyzed by Biomedical Engineering Modeling
    • 1st Edition
    • Dhanjoo N. Ghista + 1 more
    • English
    Physiology, Medicine, and Health Sciences: Catalyzed by Biomedical Engineering Modeling is a quantitative handbook for mathematical and quantitative analysis of anatomical structures, physiological and organ systems, medical tests and surgical procedures. This book’s purpose is to demonstrate how fundamental mathematical modeling can be incorporated into physiology, medicine, and health sciences research, application, and clinical practice to make these disciplines more quantitative and computational, and hence more explanatory and informative. The book also provides quantitative formulation of medical procedures, towards supporting the growing field of precision medicine. Each chapter includes a robust introduction to the BME and mathematical concepts necessary to understand their application to the indicated medical and biological systems, beginning with Intrinsic Anatomy, showing how anatomical structures are intrinsically optimally designed for their functional performance, such as the intrinsic hyperboloid shape of the spinal vertebral body (as a lightweight, high-strength structure), and the ellipsoidal shape of the left ventricle that enables it to contract efficiently. Other BME and modelling concepts covered include: Physiological Engineering, in quantifying physiological systems and developing indices for assessing their function and dysfunction leading to medical diagnostics; Precision Medicine, by developing biomedical engineering formulation of medical diagnostic and assessment methods and indices, including the new concept of non-dimensional indices in medical assessment, such as cardiac contractility index for risk of heart failure and diabetes index for accurate diagnosis of diabetes; and, Computational Surgery, involving surgical design of prosthetic devices based on the intrinsic design of the fractured structure, such as the design of the spinal vertebral body cage for fractured vertebral body to preserve its intrinsic hyperboloid shape. Each chapter provides in-depth guidance on the engineering and mathematical concepts, methodology, and procedures for applying the formulas and equations to the appropriate biomedical and physiological systems, as well as step-by-step procedures for creating models for a wealth of specific applications.

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