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Academic Press

  • Deep Learning in Genetics and Genomics

    Volume 1: Foundations and Introductory Applications
    • 1st Edition
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications, the intersection of deep learning and genetics opens up new avenues for advancing our understanding of the genetic code, gene regulation, and the broader genomics landscape. The book not only covers the most up-to-date advancements in the field of deep learning in genetics and genomics, but also a wide spectrum of (sub) topics including medical and clinical genetics, predictive medicine, transcriptomic, and gene expression studies. In 21 chapters Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications describes how AI and DL have become increasingly useful in genetics and genomics research where both play a crucial role by accelerating research, improving the understanding of the human genome, and enabling personalized healthcare. From the fundamentals concepts and practical applications of deep learning algorithms to a wide range of challenging problems from genetics and genomics, Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications creates a better knowledge of the biological and genetics mechanisms behind disease illnesses and improves the forecasting abilities using the different methodologies described. This title offers a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning-based approaches in genetics and genomics, helping researchers process and interpret vast amounts of genetic data, identify patterns, and make discoveries that would be challenging or impossible using traditional methods.
  • Mitophagy in Health and Disease

    Mechanisms, Health Implications, and Therapeutic Opportunities
    • 1st Edition
    • John J. Lemasters
    • English
    Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.
  • Bacterial Enzymes as Targets for Drug Discovery

    Meeting the Challenges of Antibiotic Resistance
    • 1st Edition
    • Punit Kaur + 1 more
    • English
    Bacterial Enzymes as Targets for Drug Discovery: Meeting the Challenges of Antibiotic Resistance addresses the gap between medical microbiology, structural biology, and genomic science in the development of new antibacterial drug development. This book consolidates detailed profiling of bacterial target enzyme families for the drug discovery process and methodologies for use and validation of the potential drug targets. The contents cover the foundations of the antibiotic drug discovery process and focus on bacterial enzymes as drug targets, building across these disciplines to provide a comprehensive resource in bacterial structural biology and genomics. This is the ideal reference for antibiotic drug discovery researchers in the pharma industry and academia. Biochemists, microbiologists, and medicinal chemists will also benefit from this books’ content.
  • Chemistry of Thermal and Non-Thermal Food Processing Technologies

    • 1st Edition
    • Brijesh K Tiwari + 1 more
    • English
    Chemistry of Thermal and Non-Thermal Food Processing Technologies provides the latest information to the food science community about the chemistry of emerging food processing technologies, including the fundamentals, recent trends, chemistry aspects in terms of quality parameters, and microbial inactivation for each technology. Divided in 4 sections, the book focus on a range of emerging technologies, such as microwave processing of food, radio frequency processing, infrared processing, ohmic heating, drying technologies, ionizing radiation processing, among others.All chapters include the following common features: principle, scope and mechanisms; effect on macromolecules (proteins, lipids, carbohydrates); effect on bioactives (Vitamins, minerals, bioactive agents); chemistry of microbial inactivation; and degradation mechanisms.
  • The Whole Person

    Toward a Naturalism of Minds and Persons
    • 1st Edition
    • Mark H. Bickhard
    • English
    The Whole Person explores the realms of theory and philosophy concerning minds and persons. This book presents models of the emergent realization of multiple mental processes, and of the constitution of social realities and social persons. Each chapter explores prevalent theoretical and philosophical assumptions that obstruct the acceptance of models depicting emergent realization, offering analyses of these barriers, and demonstrating ways to overcome them. Rooted in the framework of process metaphysics, this book models metaphysically genuine emergence, paving the way for a comprehensive model of multifarious normative emergences. These normative emergences include phenomena such as function-dysfunction... representational truth and falsity, rational-irrational, ethical-unethical, and others that shape our mental and social landscapes. The discussion extends to the macro-evolutionary culmination of mental processes in a model of reflective consciousness. The book then extends its exploration to the foundational role of mental processes in the emergence of social realities and persons, with language acting as a core element in these emergences. Addressing evolutionary aspects, brain processes, developmental processes, moral normativities, and self-consistency considerations, The Whole Person presents a holistic integration of decades of constructive work.Endorsements:"T... ambitious, yet unpretentious, carefully constructed and argued book is a must read for anyone with serious interest in the nature of persons and the psychology of personhood. Mark Bickhard’s The Whole Person is a sustained and convincing narrative about our individual and collective evolution and emergence as the unique beings that we are. Of particular interest is his account of the emergence of persons as homo-socius. Here, Professor Bickhard captures key, but often overlooked, historical, sociocultural, and socio-developmental dynamics and processes that make us who we are—a species constantly interacting with each other and the world in a never-ending process of mutual co-constitution. By theorizing a process metaphysics replete with emergent normativity that does not clash with a naturalistic ontological psychology, Bickhard takes a giant step toward seeing ourselves as we are and as we might become." -- Jack Martin, Professor Emeritus, Simon Fraser University"A typical psychological theory offers narrow generalizations about data sets obtained by semi-proprietary empirical methods. The basic empirical research on which such theories have depended is in crisis: tremendous effort has gone into ill-motivated studies, applying statistics inappropriately to inadequate samples, too often generating irreproducible results. The kind of theory that psychology needs is broad and deep, pays no respect to boundaries between specialties, makes falsifiable predictions, and answers to arguments in principle. The Whole Person presents just such a theory; psychologists, whether their aim is to extend it and support it or to challenge it and refute it, will benefit from studying it closely." -- Robert L. Campbell, Professor (Emeritus), Psychology, Clemson Universit
  • Time-Resolved Methods in Structural Biology

    • 1st Edition
    • Volume 709
    • English
    Time-Resolved Methods in Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 40
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 40 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
  • Health Literacy in Medicines Use and Pharmacy

    A Definitive Guide
    • 1st Edition
    • Ahmed Awaisu + 4 more
    • English
    Health Literacy in Medicines Use and Pharmacy: A Definitive Guide highlights issues related to medication literacy from the context of the pharmacist and other healthcare professionals. This definitive guide will undoubtedly serve as an invaluable resource for healthcare professionals in training and practice, fostering excellence in patient care globally. The book provides a clear explanation of medication literacy, presents different tools to assess health and medication literacy, readability, and comprehensibility of written medicine information (WMI), and elaborates on different approaches to develop customized and patient-friendly WMI. The book also covers health and medication literacy in special populations, including geriatrics, pediatrics, and pregnant/lactating patients. Written by experts in health communication, this book will help pharmacists, other health professionals, educators, students, and regulators, who need to develop customized educational materials that can be understood by a broad range of patients, especially those with low health literacy.
  • Women’s Contribution to F-element Science Part 2

    • 1st Edition
    • Volume 66
    • English
    Women’s Contribution to F-element Science, Part Two, Volume 66 highlights women researchers, recognizing and showcasing their unique contributions to the field. Topics include nanophosphors for near Infrared imaging and energy conversion, luminescent and upconversion nanomaterials, molecular luminescence, radiopharmaceuticals... and more. Chapters in this new release include Luminescent solar concentrators: current and future applications in smart cities, Lanthanide-Based Responsive MRI Probes, Helicate coordination complexes of rare earths and their luminescent properties, Environmental and molecular facets of uranyl(V) and uranium(V) chemistry, Versatile core/shell luminescent nanoparticles for biophotonic studies, 4f-Metal ions in single molecule magnet systems.
  • Neuropsychiatric Complications of HIV

    A Challenging Health Concern
    • 1st Edition
    • Anchal Singh
    • English
    Neuropsychiatric Complications of HIV: A Challenging Health Concern examines these neuropsychiatric complications prevalent in those who are HIV positive, providing clinical correlation, translational significance, and details guides to neurocognitive assessment, brain imaging, and related neuropharmacology. Written for clinicians, researchers, and students working with HIV and AIDS, the book begins with the biology of HIV, a complete look at available ARTs and antibodies, as well as diagnostics tools for HIV.It continues on to the epidemiology of NeuroAIDs and the manifestations of it—cognitive deficits, dementia, depression, agitation, psychosis, and cognitive slowing.