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    • Omega-3 Fatty Acids

      • 1st Edition
      • August 28, 2024
      • Peter Lembke
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 1 1 4 2
      • eBook
        9 7 8 0 4 4 3 2 9 1 1 5 9
      Omega-3 Fatty Acids: A Scientific Approach to Healthy Ageing and Optimized Nutrition looks at the biochemistry of long chain fatty acids and their importance to health, well-being, and the reduction of inflammation in the body. Divided into two parts, the book first explains the history, chemical background, and physiological pathways of how EPA and DHA influence our inflammatory response and their importance as structural building blocks within our cell membranes. Readers will learn about increasing the anti-inflammatory effects from polyunsaturated-fatt... intake by combining Omega-3s and Omega-6s, as well as the differences, safety aspects, nutritional values of plant Omegas verse animal Omegas.In additions, sections will update on the benefits of different Omega fatty acids derived from various food sources such as seeds, fish, eggs, and nuts. Part Two is dedicated to healthy aging and discusses the results of numerous clinical trials and mechanisms of action that address heart, immune, bone, muscle, cognitive, and vision health. Readers will gain insight to methods of sustainable sourcing to ensure maximum benefits and optimized nutrition.

    • Genetics and Epigenetics of Genitourinary Diseases

      • 1st Edition
      • August 27, 2024
      • Seyed Mohammad Kazem Aghamir
      • English
      • Paperback
        9 7 8 0 4 4 3 2 7 3 0 2 5
      • eBook
        9 7 8 0 4 4 3 2 7 3 0 3 2
      Genetics and Epigenetics of Genitourinary Diseases aims to provide a comprehensive collection of data on genetics and epigenetics in almost all genitourinary diseases for researchers, clinicians, and graduate students.This book discusses several genetic and epigenetic changes like DNA methylation, mutations, single nucleotide polymorphisms, DNA rearrangements, chromosomal remodeling, microsatellite instability, and chromosomal instability (CIN) in genitourinary cancers.This book is split into 18 chapters, beginning with the importance of genetics and epigenetics in genitourinary diseases. It then goes on to cover the genetics and epigenetics of various diseases and tumors. Certain chapters present novel techniques of next-generation sequencing (NGS). Furthermore, RNA-Seq is discussed as a sequencing technique that uses NGS to reveal the presence and quantity of RNA in a biological sample.This book is a valuable resource for researchers, practitioners, and students in genetics and epigenetics who want to broaden their understanding of the field.

    • The Evolution of Immunotherapy Against Tumors

      • 1st Edition
      • August 27, 2024
      • Domenico Ribatti
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 7 9 8 2
      • eBook
        9 7 8 0 4 4 3 2 1 7 9 9 9
      The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

    • Vaccines in Aquaculture

      • 1st Edition
      • August 26, 2024
      • Baskaralingam Vaseeharan + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 1 6 7 5
      • eBook
        9 7 8 0 4 4 3 2 2 1 6 8 2
      Vaccines in Aquaculture: Development, Production, and Applications acknowledges the crucial part that aquatic vaccines play in disease control for the sustainable future of aquaculture. Vaccination progression has become the most important method for disease prevention and effective prophylaxis based on stimulation of the immune systems of key aquaculture species. This book provides detailed information about the evaluation, mass production, and commercialization of aquatic animal vaccines, as well as specific descriptions of the correct use of vaccines against the most important microbial diseases of aquatic animals.Written by a leading expert in aquatic animal health biotechnology, this book is systematically organized for effective delivery of its major themes. The book starts by providing an overview on aquaculture vaccine history, evolution, and characteristic features before describing the various types of vaccines and vaccination methods in the industry. Latter sections discuss aquatic vaccine development, recent developments and challenges, mass production, and commercialization. The book concludes with an examination of the challenges associated with large-scale production, commercialization, and ethical and legal considerations.

    • From Anatomy to Function of the Central Nervous System

      • 1st Edition
      • August 25, 2024
      • Brandon Matteo Ascenzi
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 4 0 4 5
      • eBook
        9 7 8 0 1 2 8 2 2 4 3 4 2
      From Anatomy to Function of the Central Nervous System: Clinical and Neurosurgical Applications features neuroradiologic images that represent today, one of the most effective resources able to detect the anatomy of the nerve structures. Simultaneously featuring neuroimages, readers can study the functional aspects of the entire central nervous system with detailed captions that describe in detail how to use and interpret them. This book includes images of the brain dissected with the Klingler’s method and white matter fiber dissection. By integrating the anatomo-functional description with the synaptic organization of the CNS, this reference is useful for anyone who wants to understand how the activity of a nerve structure arises, describing its microstructure, neurotransmitter phenotype, and neural activity. It also features descriptions of pathologic conditions which result from neuroanatomical and/or neurofunctional alterations and includes neurosurgical aspects.

    • Intelligent Computing Techniques in Biomedical Imaging

      • 1st Edition
      • August 23, 2024
      • Bikesh Kumar Singh + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 9 9 9 2
      • eBook
        9 7 8 0 4 4 3 1 6 0 0 0 4
      Intelligent Computing Techniques in Biomedical Imaging: Methods, Case Studies, and Applications provides comprehensive and state-of-the-art applications of Computational Intelligence techniques used in biomedical image analysis for disease detection and diagnosis. The book offers readers a stepwise approach from fundamental to advanced techniques using real-life medical examples and tutorials. The editors have divided the book into five sections, from prerequisites to case studies. Section I presents the prerequisites, where the reader will find fundamental concepts needed for advanced topics covered later in this book. This primarily includes a thorough introduction to Artificial Intelligence, probability theory and statistical learning. The second section covers Computational Intelligence methods for medical image acquisition and pre-processing for biomedical images. In this section, readers will find AI applied to conventional and advanced biomedical imaging modalities such as X-rays, CT scan, MRI, Mammography, Ultrasound, MR Spectroscopy, Positron Emission Tomography (PET), Ultrasound Elastography, Optical Coherence Tomography (OCT), Functional MRI, Hybrid Modalities, as well as pre-processing topics such as medical image enhancement, segmentation, and compression. Section III covers description and representation of medical images. Here the reader will find various categories of features and their relevance in different medical imaging tasks. This section also discusses feature selection techniques based on filter method, wrapper method, embedded method, and more. The fourth section covers Computational Intelligence techniques used for medical image classification, including Artificial Neural Networks, Support Vector Machines, Decision Trees, Nearest Neighbor Classifiers, Random Forest, clustering, extreme learning, Convolution Neural Networks (CNN), and Recurrent Neural Networks. This section also includes a discussion of computer aided diagnosis and performance evaluation in radiology. The final section of Intelligent Computing Techniques in Biomedical Imaging provides readers with a wealth of real-world Case Studies for Computational Intelligence techniques in applications such as neuro-developmental disorders, brain tumor detection, breast cancer detection, bone fracture detection, pulmonary imaging, thyroid disorders, imaging technologies in dentistry, diagnosis of ocular diseases, cardiovascular imaging, and multimodal imaging.

    • FinFET/GAA Modeling for IC Simulation and Design

      • 2nd Edition
      • August 23, 2024
      • Yogesh Singh Chauhan + 10 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 7 2 9 8
      • eBook
        9 7 8 0 3 2 3 9 5 8 2 3 3
      FinFET/GAA Modeling for IC Simulation and Design: Using the BSIM-CMG Standard, Second Edition is the first to book to explain FinFET modeling for IC simulation and the industry standard – BSIM-CMG - describing the rush in demand for advancing the technology from planar to 3D architecture as now enabled by the approved industry standard. The book gives a strong foundation on the physics and operation of FinFET, details aspects of the BSIM-CMG model such as surface potential, charge and current calculations, and includes a dedicated chapter on parameter extraction procedures, thus providing a step-by-step approach for the efficient extraction of model parameters. With this book, users will learn Why you should use FinFET, The physics and operation of FinFET Details of the FinFET standard model (BSIM-CMG), Parameter extraction in BSIM-CMG FinFET circuit design and simulation, and more.

    • Epigenetic Regulation of Cancer-Part C

      • 1st Edition
      • Volume 387
      • August 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 4 4 6 2
      • eBook
        9 7 8 0 4 4 3 2 1 5 4 7 6
      Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.

    • Digital Technology in Public Health and Rehabilitation Care

      • 1st Edition
      • August 23, 2024
      • Raymond K. Y. Tong + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 2 7 0 2
      • eBook
        9 7 8 0 4 4 3 2 2 2 7 1 9
      Digital Technology in Public Health and Rehabilitation Care: COVID Era provides an in-depth examination on how digital technology has impacted public health and rehabilitation during the COVID-19 pandemic. The book showcases the range of digital technology applications utilized in healthcare, including the use of mobile phones, computers, wearable and non-wearable technologies, sensors, 3D printers, robotics, Artificial Intelligence (AI), internet technologies, websites and apps, virtual and augmented realities, and computer games. With a wealth of case studies and insights, this book is an essential resource on the impact of digital technology on public health and rehabilitation services in the COVID-19 era. The COVID-19 pandemic had a major impact on the rehabilitation services available to those in need, particularly for older adults, people with physical and cognitive impairments, children with autism and ADHD, and individuals with physical and mental health disorders. In response to these challenges, the book focuses on the potential for advanced digital technologies to revolutionize public health and rehabilitation services, highlighting the need for researchers and healthcare professionals to work together to promote digital-based interventions.

    • TRP Channels as Therapeutic Targets

      • 2nd Edition
      • August 22, 2024
      • Arpad Szallasi
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 6 5 3 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 5 4 7
      TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

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