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Elsevier

Academic Press

  • Handbook of Diffusion MR Tractography

    Imaging Methods, Biophysical Models, Algorithms and Applications
    • 1st Edition
    • Flavio Dell'Acqua + 2 more
    • English
    Handbook of Diffusion MR Tractography: Imaging Methods, Biophysical Models, Algorithms and Applications presents methods and applications of MR diffusion tractography, providing deep insights into the theory and implementation of existing tractography techniques and offering practical advice on how to apply diffusion tractography to research projects and clinical applications. Starting from the design of MR acquisition protocols optimized for tractography, the book follows a pipeline approach to explain the main methods behind diffusion modeling and tractography, including advanced analysis of tractography data and connectomics.An extensive section of the book is devoted to the description of tractography applications in research and clinical settings to give a complete picture of tractography practice today. By focusing on technology, models, and applications, this handbook will be an indispensable reference for researchers and students with backgrounds in computer science, mathematics, physics, neuroscience, and medical science.

  • Geriatric Surgery and Perioperative Care

    • 1st Edition
    • Gabriella Bettelli + 1 more
    • English
    Geriatric Surgery and Perioperative Care presents clear evidence to support regulatory and financial decisions in the light of the value-based care principles. The book outlines standards of care for elderly patients undergoing surgery as well as minimal requirements for modern management aimed at delivering cost-effective healthcare. It opens with the epidemiology and patho-physiological changes of aging and their impact on anesthesia and surgery. Subsequent chapters guide readers through the surgical process, addressing preoperative optimization, intraoperative procedures and management, and postoperative principles, including ICU care.The book concludes with ethical principles, care models, and hospital design to support a golden silver surgery using a team-based approach. This title is an important resource for healthcare professionals, practitioners, and others pursuing current strategies and methods for successful perioperative care of the elderly.

  • Horse Pasture Management

    • 2nd Edition
    • Paul H. Sharpe
    • English
    Horse Pasture Management, Second Edition provides updated coverage on strategies for managing behavior, grouping, environments and feeding needs of grazing horses. Sections cover the structure, function and identification of forages, continuing into nutritional value of pasture plants. Management of soil, the function of a pasture ecosystem and management of plants in a pasture is covered next, followed by forage yield determination, horse grazing behavior, feed choices of horses, management of grazing horses, and how to calculate how many horses should be grazing relative to land size. Advantages of grazing more than one species of animal are described. Management of hay and silage are included since year-round grazing is not possible on many horse farms. Several chapters deal with interactions of a horse farm with the environment, including climate and weather and other living things. The book also covers strategies for managing manure, erosion, and water quality. It is ideal for researchers, scientists and students involved in animal science, specifically equine studies. Agriculturists, equine managers and veterinarians will also find this book useful.

  • The Lung

    Development, Aging and the Environment
    • 3rd Edition
    • Kent Pinkerton + 2 more
    • English
    The Lung: Development, Aging and the Environment, Third Edition provides an understanding of the multifaceted nature of lung development, aging and the environment influences of these processes. As an essential resource to respiratory, pulmonary and thoracic scientists and physicians, this book provides an interface between the "normal" and "disease" cluster of chapters, allowing for a natural complement. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the "normal" pediatric lung.New research, including cell-based strategies for infant lung function, epigenetics and prenatal environmental exposure (including wildfires) on lung development and function are some of the important additions to this edition of this reference work.

  • The Three Functional States of Proteins

    Structured, Intrinsically Disordered, and Phase Separated
    • 1st Edition
    • Timir Tripathi + 1 more
    • English
    The Three Functional States of Proteins explores how structured proteins, intrinsically disordered proteins, and phase separated proteins contribute to the complexity of cellular life, and offers insights into their roles in both health and disease. It discusses the latest research findings and highlight groundbreaking discoveries and innovative methodologies used to study these protein states.Traditionally... the different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria alone may not be sufficient to capture the complex and multifaceted properties of these molecules. Definitions based on thermodynamics and kinetics are now recognized as potentially more appropriate for comprehensively understanding protein states. Emerging evidence indicates that under physiological conditions, a majority of proteins possess the capability to exist in and transition between the native, droplet, and amyloid states. These distinct states play crucial roles in various cellular functions, influenced significantly by their physicochemical and structural properties. The book also considers the interactions among these states and discusses how their internal organization as individual molecules, as well as their collective organization as molecular assemblies are stabilized. Furthermore, it examines the processes by which these states are formed and the cellular functions associated with each specific state.

  • Sustainable Management of Agro-Food Waste

    Fundamental Aspects and Practical Applications
    • 1st Edition
    • Shalini Rai + 2 more
    • English
    Sustainable Management of Agro-Food Waste: Fundamental Aspects and Practical Applications provides insights into the latest approaches for optimizing waste produced by these industries. Bioconversion of agro-food waste is a significant concern for maintaining the ecosystem. This book covers current research into the production of a variety of bioactive compounds, bioenergy resources, and nanomaterials using potential microbes associated widely with the industry’s waste. With primary focus on the microbial enzymes, secondary metabolites, single cell protein, bioethanol, biohydrogen, bio-fortified compost, bioelectricity, and nanomaterial’s, the book presents a range of biotechnological approaches.Sections describe the application of microbial niches in waste recycling and renewable energies like biofuel, plant enzymes, and hormones for different agriculture and allied sectors. With recent advancements in the synthesis of bioactive compounds, bioenergy, and nanomaterials and the discovery of their agriculture, environmental and biomedical applications, it is expected that these methods will be applied at a large scale for industrial application in different sectors. Policies required for the agro-food waste management and option for their utilization are also discussed, along with the sources of their generation.

  • Yoga for Cardiovascular Disease and Rehabilitation

    Integrating Complementary Medicine into Cardiovascular Medicine
    • 1st Edition
    • Indranill Basu Ray
    • English
    Yoga in Cardiovascular Disease and Rehabilitation: Integrating Complementary Medicine into Cardiovascular Medicine highlights recent research, clinical trials and experiments on yoga and meditation as a preventative measure against various major cardiovascular diseases, including hypertension, hyperlipidemia, coronary artery disease and metabolic syndromes.Chapters discuss yoga's role in ameliorating cardiac dysfunction and current knowledge on the effects of yoga on the brain, emotion, and other factors that initiate and perpetuate vascular inflammation. Cellular, genetic, and molecular effects of yoga based on experimental evidence are also covered in detail, providing readers with the latest research on the effects of yoga and meditation in heart diseases.This book also explores current knowledge gaps in yoga research to facilitate further research and is a comprehensive reference to scientists and clinicians interested in yoga's health effects, including preventing and treating diseases.

  • Diagnosing Musculoskeletal Conditions using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging

    • 1st Edition
    • Rakesh Kumar + 3 more
    • English
    Bone deformations can lead to musculoskeletal disorders and negatively impact on individual quality of life. Early and accurate detection of bone deformation is crucial for effective medical intervention. Diagnosing Musculoskeletal Conditions Using Artificial Intelligence and Machine Learning to Aid Interpretation of Clinical Imaging outlines a comprehensive approach that integrates Artificial Intelligence (AI) and Machine Learning (ML) techniques to identify bone deformations promptly and accurately. By leveraging advanced image analysis and pattern recognition, this approach aims to revolutionize the field of orthopedic diagnostics. This book covers challenges, technologies, applications, and future trends of AI and ML in Bone Deformation, addressing advanced and innovative techniques, frameworks, methodologies, and practical implementations of machine learning to get early predictions of Bone deformation. Written by experts in the field for researchers, surgeons, students, and instructors interested in musculoskeletal conditions.

  • Nonclinical Development of Biologics, Vaccines and Specialty Biologics

    • 2nd Edition
    • Lisa M. Plitnick + 1 more
    • English
    Nonclinical Development of Biologics, Vaccines and Specialty Biologics, Second Edition, is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, vaccines, cell and gene therapies, and oncology therapeutics. Updated and revised, the new edition compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory guidelines. This book discusses the different types of biologics, as well as early characterization strategies, principles of study design, nonclinical pharmacokinetics and pharmacodynamics, nonclinical assays, and regulatory guidelines. A coedited book with chapters authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late-stage biologics.

  • Vagus Nerve Stimulation

    • 1st Edition
    • Peter Staats + 3 more
    • English
    In the complex realm of our physiology, the vagus nerve stands as a silent orchestrator, influencing health and disease in ways that have long been underestimated. Vagus Nerve Stimulation delves into the profound significance of this 10th cranial nerve, tracing its course through the body and illuminating its role as a vital component of the parasympathetic nervous system.This comprehensive reference, contributed by leading experts at the forefront of medical science, unveils the groundbreaking field of vagus nerve stimulation—a non-invasive approach to harness the body's innate potential for health optimization, inflammation control, and disease modification. Contributed by leading experts in the field, this comprehensive volume serves as a compendium of current knowledge about stimulating the vagus nerve in many different disease states. This book starts with the foundational insights in Basic Science and Technical Considerations. From there, it continues to Neurologic Conditions, where chapters explore applications for epilepsy, cluster headaches, and concussions. Evolving Therapy for Neurologic Conditions introduces cutting-edge treatments for acute ischemic stroke, synaptic plasticity, and neurodegenerative disorders. The book extends into Psychiatric and Somatic Conditions, providing insights into anxiety, depression, addiction disorders, and more. Conventional Inflammatory Conditions shed light on vagus nerve stimulation's role in combatting sepsis, immune-mediated inflammatory diseases, and metabolic syndrome, among others. Concluding with a foray into Oncology, the book highlights the potential of vagus nerve stimulation in addressing the lingering effects of long covid and migraine. With an authoritative blend of scientific rigor and practical application, this reference serves as an indispensable guide to the vast landscape of vagus nerve stimulation, transforming our understanding of health and wellness.

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