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    • Data Driven Analysis and Modeling of Turbulent Flows

      • 1st Edition
      • March 17, 2025
      • Karthik Duraisamy
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 0 4 3 5
      • eBook
        9 7 8 0 3 2 3 9 5 0 4 4 2
      Data-driven Analysis and Modeling of Turbulent Flows provides an integrated treatment of modern data-driven methods to describe, control, and predict turbulent flows through the lens of both physics and data science.The book is organized into three parts:• Exploration of techniques for discovering coherent structures within turbulent flows, introducing advanced decomposition methods• Methods for estimation and control using data assimilation and machine learning approaches• Finally, novel modeling techniques that combine physical insights with machine learningThis book is intended for students, researchers, and practitioners in fluid mechanics, though readers from related fields such as applied mathematics, computational science, and machine learning will find it also of interest.

    • Protein Misfolding in Neurodegenerative Diseases

      • 1st Edition
      • March 17, 2025
      • Neha Gogia + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 7 1 6 2
      • eBook
        9 7 8 0 4 4 3 1 8 7 1 7 9
      Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

    • Multi-Omics Technology in Human Health and Diseases

      • 1st Edition
      • March 17, 2025
      • Muzafar A Macha + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 3 5 9 5 8
      • eBook
        9 7 8 0 4 4 3 1 3 5 9 6 5
      Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic offers an advanced exploration into the comprehensive understanding of disease etiology and prognosis through multiomics approaches. This authoritative volume delves into the applications of multiomics technology in elucidating complex human health conditions and diseases. It introduces the technology's potential for biomarker identification, drug discovery, and disease prognostication. For a thorough understanding of human health and diseases, particularly cancer, it is essential to integrate knowledge of molecular biomarkers across multiple omics levels, including the genome, epigenome, transcriptome, proteome, and metabolome. This resource addresses the current gaps in knowledge among students and researchers, providing in-depth coverage of multiomics technology and its implementation in scientific research and discovery.Multi-Omic... Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics is a pioneering resource that presents cutting-edge information on contemporary multiomics technologies for big data interpretation and their applications in deciphering complex human pathobiology. This comprehensive guide is indispensable for researchers, academics, students, and industry professionals alike.

    • Federated Learning for Medical Imaging

      • 1st Edition
      • March 17, 2025
      • Xiaoxiao Li + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 6 4 1 9
      • eBook
        9 7 8 0 4 4 3 2 3 6 4 2 6
      Federated Learning for Medical Imaging: Principles, Algorithms, and Applications gives a deep understanding of the technology of federated learning (FL), the architecture of a federated system, and the algorithms for FL. It shows how FL allows multiple medical institutes to collaboratively train and use a precise machine learning (ML) model without sharing private medical data via practical implantation guidance. The book includes real-world case studies and applications of FL, demonstrating how this technology can be used to solve complex problems in medical imaging. The book also provides an understanding of the challenges and limitations of FL for medical imaging, including issues related to data and device heterogeneity, privacy concerns, synchronization and communication, etc.This book is a complete resource for computer scientists and engineers, as well as clinicians and medical care policy makers, wanting to learn about the application of federated learning to medical imaging.

    • Glucose Transporters

      • 1st Edition
      • Volume 128
      • March 17, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 5 2 2
      • eBook
        9 7 8 0 4 4 3 2 9 5 5 3 9
      Glucose Transporters, Volume 128 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Glucose transporters and their energy homeostasis function in various organs, Molecular basis for inhibiting glucose transporters by exofacial inhibitors, Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake, The role of lipid soluble vitamins on glucose transporter, Transport of dehydroascorbic acid by glucose transporters GLUTs, Glut-1 Inhibition in Breast Cancer Cells, Small-molecule inhibitors of glucose transporters, and more.

    • Wheat Wild Relatives

      • 1st Edition
      • March 17, 2025
      • Mohd. Kamran Khan + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 2 0 9 0 6
      • eBook
        9 7 8 0 4 4 3 2 2 0 8 9 0
      Wheat Wild Relatives: Developing Abiotic Stress Tolerance under Climate Change presents a state-of-the-art outline of the problem, including issues, opportunities, and modern developments in the utilization of Wild Wheat Relatives (WWR) and related neglected species for wheat crop improvement, specifically focusing on environmental constraints. The book comprehensively discusses different wheat wild relatives, including major genus Triticum and Aegilops and their utilization in mitigating different environmental constraints using agronomic, physiological, and molecular approaches. Chapters provide insights into the advancement in the deployment of wheat genetic resources, including wild relatives and neglected species for crop improvement towards environmental issues.Wheat is a major staple food crop that has largely been focused for fulfilling the food requirements of world population during the Green revolution. Since then, it has come to cover more agricultural land than any other commercial crop. Continuously changing climatic conditions have drastically affected wheat production, with yields largely limited by environmental constraints. Theses production losses caused by crop vulnerability to climate change may be resolved by using wheat wild relatives that are closely related to cultivated genotypes and known for their beneficial traits.

    • Human- Centric Integration of Next-Generation Data Science and Blockchain Technology

      • 1st Edition
      • March 17, 2025
      • Amit Kumar Tyagi + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 4 9 8 6
      • eBook
        9 7 8 0 4 4 3 3 3 4 9 9 3
      Human- Centric Integration of Next Generation Data Science and Blockchain Technology: Advancing Society 5.0 Paradigms focuses on the current technological landscape, addressing the evolving integration of data science and blockchain within the context of Society 5.0. This comprehensive resource explains the convergences between data science, blockchain, and the human-centric vision of Society 5.0, while also filling the gap in understanding and navigating this transformative intersection with recent shifts towards more decentralized and data-driven paradigms.The book introduces the concept of Society 5.0, examining the historical context, and outlines the evolving technological landscape shaping our interconnected future. It discusses the fundamental principles of data science, from data collection and preprocessing to exploratory data analysis and explains the transformative impact of data science and blockchain across industries such as healthcare, finance, education, and transportation. This book is essential to understanding and shaping the future of technology and society from decentralized solutions to predictive analytics/ emerging technologies.

    • Lipid-Drug Conjugates

      • 1st Edition
      • March 17, 2025
      • Malay K. Das
      • English
      • Paperback
        9 7 8 0 4 4 3 3 3 3 8 2 8
      • eBook
        9 7 8 0 4 4 3 3 3 3 8 3 5
      Lipid-Drug Conjugates: Innovation and Applications highlights the most recent advances and clinical applications of nano lipid-drug conjugates for enhanced drug delivery and targeting in the treatment of cancer, glioblastoma, Alzheimer’s, AIDS, and bacterial diseases. In addition, various conjugation methods to prepare lipid-drug conjugates and their pharmacokinetics in vivo are explored, together with the production and characterization of various delivery carriers for lipid-drug conjugates. The contents of this book provide pharmaceutical science researchers with the tools to explore targeted drug delivery leveraging the unique characteristics of lipid conjugates. Scientists in the corporate setting can benefit of the cases and techniques presented in developing new formulations and products.

    • Differentiating Factors in Alzheimer’s Disease

      • 1st Edition
      • March 17, 2025
      • Henry M Zeidan + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 6 3 2 9
      • eBook
        9 7 8 0 4 4 3 2 1 6 3 3 6
      Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.

    • A Comprehensive Guide to Rodent Models of Liver Diseases

      • 1st Edition
      • March 15, 2025
      • Savneet Kaur + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 4 7 8 1
      • eBook
        9 7 8 0 3 2 3 9 9 4 7 9 8
      A Comprehensive Guide to Rodent Models of Liver Diseases provides the why, what, and how of preclinical models of liver disease. These models have not only substantially improved understanding of human liver disease pathogenesis, but also helped in developing and testing newer therapeutics as well as addressed some of the unanswered medical challenges and problems of today.This important reference gives a detailed and in-depth review of the various animal models of human liver disorders. Well-reported animal models several human liver diseases such as fatty liver disease (non-alcoholic and alcoholic) to steatohepatitis, cholestasis, fibrosis, cirrhosis and its complications are described. Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, brief protocols, relevance, and limitations are provided.Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, updated protocols, relevance, and limitations are provided for consideration. Finally, it provides an overview of the recently developed organoid models of liver pathology.

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