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Academic Press

  • Targeted Protein Degradation Technologies

    • 1st Edition
    • Jiangjiang Qin + 2 more
    • English
    Targeted Protein Degradation Technologies offers a comprehensive exploration of the field of targeted protein degradation, from its latest scientific advancements to its potential therapeutic applications. This book begins with a foundational introduction to the mechanisms of protein degradation, followed by an in-depth look at both protease-mediated and lysosome-mediated degradation pathways. The text delves into a range of cutting-edge technologies, including PROTAC, AbTAC, molecular glues, hydrophobic tagging, LYTAC, GlueTAC, and AUTAC. It then explores the development of degraders for specific proteins, such as signal transduction receptors, membrane proteins, and transcription factors. This book concludes with a focused discussion on the clinical applications of targeted protein degradation and provides an insight into the future directions for this field.This book serves as an invaluable resource for researchers and professionals in molecular biology, cell biology, and related disciplines, particularly those involved in protein degradation and the development of novel therapeutic strategies.
  • Recent Developments of Molecular Electronic Structure Theory

    • 1st Edition
    • Volume 91
    • English
    New Insights into Molecular Electronic Structure Theory, Volume 91 in the Advances in Quantum Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
  • Stochastic Modeling and Statistical Methods

    Advances and Applications
    • 1st Edition
    • Ioannis S. Triantafyllou + 2 more
    • English
    Stochastic Modeling and Statistical Methods: Advances and Applications is the practical guide to the latest developments in data analysis and research methods. The book explores the significant research progress that has been seen in recent decades, offering vital tools for analyzing modern applications and real data. Topics covered include Dynamic Reliability, Stochastic Modeling, System Maintainability, and Parametric, Semi-Parametric, and Nonparametric Statistical Inference. Readers will find the latest advancements in these areas, making it an essential resource for researchers and practitioners who want to explore these evolving fields and stay updated on cutting-edge research.
  • Cell Migration in Development

    • 1st Edition
    • Volume 164
    • English
    Cell Migration in Development, Volume 163 highlights new advances in the field, with chapters written by an international board of authors who update on high-profile topics such as. Single-cell migration in development - lessons from germ-cells, Lipid/membrane regulation during cell migration and invasion, Remodeling of the extracellular matrix and cell-matrix adhesion during collective cell migration, From cessation of neural crest migration to onset of gangliogenesis, Collective migration in confined spaces: the case of trunk neural crest, From single to collective: the mechanisms underlying cell migration in early development, Direct and indirect roles of Nodal signaling in developmental cell migration.
  • Reproductive Immunogenetics: A Molecular and Clinical Overview

    Immune Cells and Immunotherapeutics in Recurrent Pregnancy Loss
    • 1st Edition
    • Shafat Ali + 2 more
    • English
    Immunogenetics: A Molecular and Clinical Overview: Immunogenetic Factors and Signaling Pathways in Recurrent Miscarriage, Volume Four provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In seventeen chapters, the book describes the roles of several different signaling pathways and the role of JLA and microRNAs in recurrent pregnancy loss. Several chapters are dedicated to the role autoimmune antibodies play in recurrent pregnancy loss. This book is a valuable resource for health professionals, scientists, researchers, and all those who wish to broaden their knowledge in the allied field.
  • Reproductive Immunogenetics: A Molecular and Clinical Overview, Vol. 3

    Immunogenetic Factors and Signaling Pathways in Recurrent Pregnancy Loss
    • 1st Edition
    • Shafat Ali + 2 more
    • English
    Immunogenetics: A Molecular and Clinical Overview, Vol. 3, Immune Cells and Immunotherapeutics in Recurrent Miscarriage provides an overview of the scientific knowledge, achievements, and findings in the field of immunogenetics of recurrent pregnancy loss. With a strong focus on the role immune cells can play in recurrent pregnancy loss, the book also examines immune therapeutic aspects. In fifteen chapters, the book describes the roles of both helper cells, nature killer cells, lymphoid cells, regulatory cells and macrophages in recurrent pregnancy loss. In addition, it describes clinical outcomes of several therapies and gives insight into new treatments. This new release is a valuable resource for health professionals, scientists and researchers, and all those who wish to broaden their knowledge in the allied field.
  • Encyclopedia of Monetary Policy, Financial Markets and Banking

    • 1st Edition
    • Nicholas Apergis
    • English
    Encyclopedia of Monetary Policy, Financial Markets and Banking, Three Volume Set presents expert commentary from professionals around the globe who analyze and forecast topics surrounding monetary policy and financial markets. As the go-to reference for the field, sections cover The Future of Monetary Policy and how leading advanced economies have undergone several fundamental transformative changes, Climate Change and Sustainability and how its impacts exert additional pressure on natural resources, Financial Markets and new frameworks for looking at financial system design, and Banking Developments, including ongoing changes in global banking influence.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 130
    • English
    Advances in Applied Microbiology, Volume 130 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.
  • Non-coding RNA

    • 1st Edition
    • Volume 214
    • English
    Non-coding RNA, Volume 214 in the Progress in Molecular Biology and Translational Science series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as An introduction to non-coding RNAs, Non-coding RNAs in Eutherians and Livestocks, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Non-coding RNAs in Plants, Epigenetic and experimental approaches influencing ncRNAs, Noncoding RNAs in bacteria, Dissecting ncRNA pathways and omics integration, Structural prediction of potent ncRNAs, Artificial intelligence and machine learning heuristics for discovery of ncRNAs in humans, Tools and Databases for non-coding RNAs, and Physiogenomics and genetic landscape of ncRNAs.
  • Intelligent Urban Mobility

    Decision Support Systems for Sustainable Transportation
    • 1st Edition
    • Muhammet Deveci
    • English
    Intelligent Urban Mobility: Decision Support Systems for Sustainable Transportation explores the role of technology in enabling greener, more accessible transportation in cities worldwide. This book provides insights into leveraging decision support systems to drive positive change by focusing on applied soft computing techniques, artificial intelligence, and algorithms for fuzzy systems. Researchers and professionals will find actionable information on mitigating congestion and emissions through sustainable mobility initiatives, which bridges the gap between theory and real-world practice.The book also offers technical guidance and expert perspectives on the application of decision support systems to evaluate and optimize planning for sustainable transit options. The book highlights innovative models and frameworks for analyzing mobility options and planning sustainable transport systems. It is an essential resource for researchers, graduate students, and professionals in transportation, urban planning, civil engineering, and decision sciences who aim to redesign city transportation to reduce environmental impact and carbon emissions.