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Academic Press

  • Heart Failure in the Child and Young Adult

    From Bench to Bedside
    • 2nd Edition
    • Joseph Rossano + 5 more
    • English
    Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine.This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.

  • Machine Learning in Drug Development: Part 1

    • 1st Edition
    • Volume 64
    • English
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

  • Myasthenia Gravis, Part B

    • 1st Edition
    • Volume 183
    • English
    Myasthenia Gravis, Part B, Volume 183 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Typical and Atypical Clinical Presentations, Diagnosis and Differential Diagnosis, Clinical Evaluation, Myasthenia Gravis in Women, Fatigue and Myasthenia Gravis, Clinical and Electrophysiologic Outcomes, Standard Treatment and Different Geographical Approaches, Rescue Treatments, Novel Treatments for Myasthenia Gravis, Measuring Treatment-Related Side Effect Burden in Myasthenia Gravis, Exercise and Myasthenia Gravis, The Social and Personal Impact of Myasthenia Gravis, and Future Perspectives.

  • Biomarkers in Kidney Transplantation

    Clinical Aspects and Laboratory Determinations
    • 1st Edition
    • Dr Smita Pattanaik + 1 more
    • English
    Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers.Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.

  • Interaction of Food Macromolecules

    The Matrix of Future Foods
    • 1st Edition
    • Ibrahim Khalifa + 2 more
    • English
    Interaction of Food Macromolecules: The Matrix of Future Foods provides a detailed understanding on why biological macromolecules, i.e., proteins, lipids, and carbohydrates with ligands interactions are essential to understanding biology at the molecular level. The book aims to create a multidisciplinary forum of discussion on the interaction between macromolecules and ligands, providing an understanding on how biological macromolecules with ligands interactions are central to facilitating the discovery, design, and development of future, functional foods. In addition, it outlines information available on the macromolecules-ligan... interaction that happens inside the food matrixes and inside our bodies.Knowing about the mechanisms responsible for the macromolecules-ligan... recognition and binding facilitates the discovery, design, and development of future and functional foods.

  • Harnessing Quorum Quenching for Disease Management

    • 1st Edition
    • Arpita Roy + 2 more
    • English
    Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.

  • Bladder Cancer Breakthroughs

    A Global Perspective on Diagnosis, Treatment, and Patient Care
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is a groundbreaking scientific resource that delves into the latest advancements in the diagnosis and treatment of bladder cancer, a prevalent malignancy affecting hundreds of thousands worldwide. This meticulously curated volume brings together contributions from leading scientists and healthcare professionals from around the globe, providing a comprehensive overview of contemporary understanding and innovative strategies in managing this complex disease. Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is not merely a collection of research findings; it is a vital resource that fosters a holistic perspective on patient-centered care. By synthesizing clinical expertise and evidence-based practices, this book aims to empower healthcare providers with the knowledge and tools needed to improve outcomes for individuals living with bladder cancer, ultimately contributing to the global fight against this challenging disease. This book serves as an essential guide for healthcare providers, including physicians, oncologists, immunologists, pharmacists, and physical therapists, striving to enhance patient care and treatment outcomes

  • Encyclopedia of Immunobiology

    • 2nd Edition
    • Paul Kaye
    • English
    Encyclopedia of Immunobiology, Second Edition, Five Volume Set covers the full range of Immunology, presenting topics logically and making extensive use of "hot links" to refer the reader to related content. The new edition is not just an update of the original title; it vastly expands fields like immunotherapy, immunity to viral infection, vaccine development, inflammatory responses, and high throughput analyses. Containing 350 chapters written by world-leading experts, this edition integrates all concepts coherently and logically to paint a comprehensive picture of the evolving field of Immunology.The immune system, complex and multi-layered, has evolved to differentiate between "self" and foreign pathogens, providing protection against infections while dysregulation can cause diseases like autoimmunity, allergies, and inflammatory disorders. This understanding has led to numerous therapeutic interventions crucial for human health improvement.

  • Hazardous Chemicals in Medical Devices

    Safety, Risk Analysis, and Regulations
    • 1st Edition
    • Prakash Srinivasan Timiri Shanmugam + 1 more
    • English
    Hazardous Chemicals in Medical Devices: Safety, Risk Analysis, and Regulations provides a comprehensive overview of the hazardous chemicals used in medical device manufacturing. The book discusses the basics of these chemicals, their presence in various components, and the regulations that govern their use. It also delves into the processes involved in manufacturing and the added chemicals during these stages. With a focus on risk assessment and analysis, the book emphasizes the importance of safety in medical devices and outlines the types of hazards associated with these substances.The book further explains the regulatory classification of hazardous chemicals and the labeling and safety data sheet requirements. It includes a list of notified bodies that discuss hazardous substance data, aiding in risk assessment and toxicological profiling. Additionally, it underscores the critical understanding of toxicological profiles of materials used in medical devices, ensuring that readers are well-informed about the safety measures and regulations in place to protect both manufacturers and users.

  • Lipases

    Foundations, Applications, and Perspectives
    • 1st Edition
    • Eliane Pereira Cipolatti + 2 more
    • English
    Lipases: Foundations, Applications, and Perspectives, a new volume in the Foundations and Frontiers of Enzymology series, offers a practical, in-depth discussion of lipases and instruction in their use across research and industry. Here, global experts in the field introduce readers to basic lipase biology and the history of the field, interfacial activation and lipase lids, evolving analytical techniques and technology for studying lipases, and a range of lipase applications, from health and drug discovery to biofuels, food, cosmetics, and waste treatment. Lipase sources and production methods discussed include mammalian lipases, microbial lipase production, biomass lipase production, immobilized lipases, and tailor-made recombinant lipases, among other approaches.

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