Skip to main content
View Cart

Academic Press

  • Machine Learning Solutions for Inverse Problems: Part A

    • 1st Edition
    • Volume 26
    • English
    Machine Learning Solutions for Inverse Problems: Part A, Volume 26 in the Handbook of Numerical Analysis, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Data-Driven Approaches for Generalized Lasso Problems, Implicit Regularization of the Deep Inverse Prior via (Inertial) Gradient Flow, Generalized Hardness of Approximation, Hallucinations, and Trustworthiness in Machine Learning for Inverse Problems, Energy-Based Models for Inverse Imaging Problems, Regularization Theory of Stochastic Iterative Methods for Solving Inverse Problems, and more.Other sections cover Advances in Identifying Differential Equations from Noisy Data Observations, The Complete Electrode Model for Electrical Impedance Tomography: A Comparative Study of Deep Learning and Analytical Methods, Learned Iterative Schemes: Neural Network Architectures for Operator Learning, Jacobian-Free Backpropagation for Unfolded Schemes with Convergence Guarantees, and Operator Learning Meets Inverse Problems: A Probabilistic Perspective

  • Nitrogen Heterocycles in Cancer Therapy

    • 1st Edition
    • Sanjeev Kumar Sahu + 1 more
    • English
    Nitrogen Heterocycles in Cancer Therapy explores the vast array of recently discovered nitrogen-containing heterocyclic compounds utilized in combating cancer. This comprehensive work not only highlights the fundamentals of oncology but also explains the intricacies of designing, synthesizing, and understanding the anticancer mechanisms of these compounds. Spanning across 10 chapters, the book explores the principles underlying the design, synthesis, and anticancer mechanisms of nitrogen-containing heterocyclic compounds, drawing from the latest research findings. Its scope extends beyond molecular targeting to encompass the exploration of newly identified heterocyclic compounds with potential anticancer properties. A significant emphasis is placed on crucial evaluation techniques such as in-vitro cell culture and in-vivo animal models, providing insights into the performance of these compounds in combating cancer. Particularly noteworthy is the inclusion of clinical study reports detailing the efficacy of various drug candidates across different cancer conditions, coupled with an analysis of their global market impact and pharmacoeconomics. Offering profound insights, this book emerges as an indispensable resource for researchers, clinicians, and students alike.

  • Future of Internet of Bio-Nano Things in Personalized Healthcare

    Applications and Challenges
    • 1st Edition
    • Jayachitra Sekar + 3 more
    • English
    Future of Internet of Bio-nano Things in Personalized Healthcare: Applications and Challenges explores the core principles of nanomaterials and the sensing paradigms essential for medical devices based on nano-sensors technology, examining the latest theoretical and practical developments in Internet of Bio-nano Things (IoBNT) for health applications. This book explores how IoBNT facilitates the detection and treatment of diseases within the human body through communication between an in-body network of nanodevices and an external control unit. Readers will discover the transformative benefits of IoBNT, which integrates information and communication technologies with medical and nano-bio sensor devices to enhance patient care. The book highlights advances in telemedicine, including highly functional electronic medical devices like implantable and wearable devices engineered through nanotechnology. It details real-time case studies on smart drug delivery, edge computing, and personalized healthcare applications to provide valuable insights into optimizing network performance and utilization in personalized healthcare. The comprehensive exploration of machine learning algorithms and communication protocols further equips readers with the knowledge to design and implement end-to-end IoBNT solutions.

  • Maternal-Fetal and Neonatal Endocrinology

    Physiology, Pathophysiology, and Clinical Management
    • 2nd Edition
    • Christopher S. Kovács + 1 more
    • English
    Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.

  • Handbook of Melatonin-Based Therapy and its Applications

    • 1st Edition
    • Alejandro Romero Martínez + 2 more
    • English
    Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.

  • Isothermal Titration Calorimetry in Enzymology

    Techniques and Applications
    • 1st Edition
    • Anthony Mittermaier + 1 more
    • English
    Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.

  • Polyamines-Phytohormones-Nutrients Network

    Nexus in Plant Responses to Abiotic Stresses
    • 1st Edition
    • Asim Masood + 3 more
    • English
    Polyamine-Phytohormo... Network: Nexus in Plant Responses to Abiotic Stresses presents the latest global research on key tools for improving physiological and biochemical mechanisms that enhance plant health and productivity.Exposur... of plants to abiotic stresses is inevitable, often leading to impaired growth, metabolism, and productivity. However, plants are naturally equipped with endogenous chemicals including intracellular messengers and signalling molecules that counteract potential stress impacts, protect cellular functions, and promote healthy growth and production. Polyamines (PAs) are low-molecular-weight... nitrogen-containing compounds with aliphatic polycationic properties. Beyond their role in growth and development, PAs enhance plant tolerance to abiotic stresses. Given their connection with phytohormones and mineral nutrients, understanding their interactions—whether synergistic or antagonistic—could shed light on their potential to mitigate these stresses.Written by a team of expert contributors, this volume in the Plant Biology, Sustainability, and Climate Change series focuses on the interactions among PAs, phytohormones, and mineral nutrients that are crucial for regulating nutrient assimilation, carbon fixation, and secondary metabolic pathways.

  • Sleep and Cancer

    • 1st Edition
    • Maria Paola Mogavero + 3 more
    • English
    Sleep and Cancer compiles novel information on the interactions between sleep and cancer. The book highlights how prevention and treatment of sleep disturbances in clinical cancer practice helps prevent the onset of tumors and their comorbidities, both short- and long-term. It analyzes how sleep disorder treatment improves the response to antitumor therapy in the long term, presenting procedures regarding cognitive-behavioral therapy of sleep disorders that are often overlooked in the oncological field.In addition, the book suggests new therapeutic approaches in oncology that are based on the knowledge of sleep mechanisms, such as chronotherapy, use of melatonin as an adjuvant in chemo- and radiotherapy, and orexinergic drugs.

  • Biopharmaceutical Ecosystems

    A Comparative Study of U.S. and European Systems
    • 1st Edition
    • David R. Williams
    • English
    The ecosystem perspective on organizations and economic settings is relatively new. It expands on work that looks at bio-clusters, concentrating on the relationship between human and financial capital. The perspective takes an expansive view of biopharmaceuticals in relation to stakeholders and the social, political, and economic landscape, including other life science companies, academia, non-profits, government entities, and health systems. The biotechnology and pharmaceutical industries have been merging for some time, with biotechnology often portrayed as a disruptive innovation to the pharmaceutical industry. A fuller description of this activity put into the greater context of the ecosystem perspective is warranted.Biopharmac... Ecosystems: A Comparative Study of U.S. and European Systems puts forward a picture of biopharmaceutical ecosystems in the USA and Europe. It examines and expands current thinking on the development of the ecosystem perspective on biopharmaceuticals. The title considers multiple locations, with countries in the top 15 of biopharmaceutical exporters selected. It pays particular attention to shifts in the political and economic landscape, and how such changes affect ecosystems. The underlying aim of biopharmaceutical ecosystems is to further the development of new drugs, reduce time to market, and lower costs. In explaining ecosystems, the book applies a quadruple helix model - academia; consumer/society; government; and industry - to each region and country in light of this triple aim.

  • Fundamentals of Brain Organoids for Neurological Diseases

    • 1st Edition
    • Balachandar Vellingiri + 1 more
    • English
    Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. Fundamental of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.

Browse by Publisher