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    • Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

      • 1st Edition
      • Volume 211
      • February 18, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 3 2 0 7
      • eBook
        9 7 8 0 4 4 3 2 9 3 2 1 4
      Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrilla... propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of α-synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.

    • Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

      • 2nd Edition
      • February 18, 2025
      • Mahendra Rai
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 0 4 4 2
      • eBook
        9 7 8 0 4 4 3 2 9 0 4 5 9
      Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.

    • Navigating Endophytic Research for Next-Generation Therapeutics

      • 1st Edition
      • February 17, 2025
      • Vagish Dwibedi + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 1 4 8 4 1
      • eBook
        9 7 8 0 4 4 3 3 1 4 8 5 8
      Navigating Endophytic Research for Next-Generation Therapeutics explores the evolving field of endophytic fungal research and applications in combating diseases, addressing environmental challenges, and in shaping the future of therapeutics. The book starts off with a discussion on the biodiversity and biogeography of endophytic fungal communities and describes the bioprospecting of endophytes for drug discovery. In addition, it covers the therapeutic application of endophytic fungi to treat and manage specific diseases and investigates the innovative use of technologies such as genome editing, genetic engineering for enhanced bioactivity, multi-omics-based exploration, and the use of big data and machine learning in endophytic drug discovery.Featuring contributions from experts across fields like mycology, pharmacology, biotechnology, and environment science, this comprehensive, practical, and insightful resource guides those engaged in endophytic fungal research and its transformative potential in next-generation therapeutics.

    • Advances in Experimental Social Psychology

      • 1st Edition
      • Volume 71
      • February 17, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 4 1 4 4 5 9
      • eBook
        9 7 8 0 4 4 3 4 1 4 4 6 6
      Advances in Experimental Social Psychology, Volume 71 in a series that is considered the premier outlet for reviews of mature, high-impact research programs in social psychology covers a variety of topics, with this release containing chapters on Understanding the Causes and Consequences of Belief in Conspiracy Theories, Fostering Inclusion: A Model for Understanding the Factors that Enhance and Undermine Identity-Safety, Intellectual Humility: On Understanding Our Limits, Ideology, Motivation, and the Connection between Cognition and Behavior, The Psychology of Science Rejection, and more.Contributions to the series provide defining pieces of established research programs, reviewing and integrating thematically related findings by individual scholars or research groups.

    • Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases

      • 1st Edition
      • February 14, 2025
      • Anoop Kumar + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 8 8 3 6 4
      • eBook
        9 7 8 0 4 4 3 2 8 8 3 7 1
      Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases discusses how nanotechnology aids in overcoming the existing traditional approaches in combating diseases. The book explores the emerging trends of using nanoparticles for nanotherapeutics and nanotheranostics and their role in the efficient diagnosis and treatment of infectious microbial diseases. Sections covers nanotherapeutic impregnated medical devices, nanotherapeutics as vaccines, related regulatory requirements, the application of nanotherapeutics and nanotheranostics in diagnosing and treating specific infectious diseases, including bacterial infections, viral infections, fungal infestations, parasitic infestations, and other infectious conditions.With chapter contributions from experts in the fields, this book offers a comprehensive reference for researchers, scientists, and industry professionals working on infectious diseases and the application of nanoparticles to effectively diagnose, treat, and manage them.

    • Advances in Heterocyclic Chemistry

      • 1st Edition
      • Volume 145
      • February 14, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 6 6 0 9
      • eBook
        9 7 8 0 4 4 3 3 1 6 6 1 6
      Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • Advances in Optics of Charged Particle Analyzers: Part 2

      • 1st Edition
      • Volume 233
      • February 10, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 1 7 2 0 0
      • eBook
        9 7 8 0 4 4 3 3 1 7 2 1 7
      Advances in Optics of Charged Particle Analyzers: Part Two, Volume 233 merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. The release in the series features articles on Electrostatic Energy, Mass Analyzers With Combined Electrostatic and Magnetic Fields, Mass Analyzers based on Fourier Transform, Principles of Time-of-Flight Mass Analyzers, Multi-Pass Time-of-Flight Mass Analyzers, and Radiofrequency Mass Analyzers.

    • The Auditory Cerebellum

      • 1st Edition
      • February 9, 2025
      • Jos J. Eggermont
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 8 4 7 9
      • eBook
        9 7 8 0 4 4 3 2 9 8 4 8 6
      The Auditory Cerebellum: Function and Dysfunction focuses on the sensory and cognitive aspects of the cerebellum, with an emphasis on hearing, speech, music, speaking, and singing. This book fills the gap for information needed in audiology and auditory neuroscience, tinnitus, and developmental disorders with a strong auditory component. This book starts with a general overview on the connectivity between the cerebellum and auditory subcortical and cortical areas, including general cortical networks. There are several chapters devoted to the timing aspects of the cerebellum underlying speech and music perception as well as motor aspects in speaking and singing.Also discussed is the role of the cerebellum in hearing impairment, tinnitus, developmental disorders with a strong auditory component, including dyslexia, autism, attention deficit, and hyperactivity disorder. Dr. Jos Eggermont, a leading researcher in the field, uses a systems analysis approach that covers electrophysiology and neural imaging, both in animals and humans.

    • Haschek and Rousseaux's Handbook of Toxicologic Pathology Volume 5: Toxicologic Pathology of Organ Systems

      • 4th Edition
      • February 9, 2025
      • Wanda M Haschek + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 0 4 5 1
      • eBook
        9 7 8 0 4 4 3 2 3 8 5 0 5
      Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, Volume Five: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals, and biologics. This book continues coverage of Organ-Specific Toxicologic Pathology and major organ systems not covered in Volume Four, and has been completely revised, making it an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

    • Patterns, Function and Application of Seed Microbiome

      • 1st Edition
      • February 6, 2025
      • Mohammad Yaseen Mir + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 4 7 7 6 7
      • eBook
        9 7 8 0 4 4 3 2 4 7 7 7 4
      Patterns, Function and Application of Seed Microbiome: Bacteria, Fungi and Viruses presents the current understanding of seed and microbiota associations, emphasizing recent findings that highlight the latest insights into these interactions, and how they may ultimately influence plant ecology, health and productivity in both natural and agricultural systems. The development and dispersal of seeds and their transition to seedlings are among the most critical stages of the life cycle of plants and seed health is of crucial global importance for producing both quantity and high quality crops to feed world’s population. It is important for seeds to be produced that contain the best hybrid embryo so that it is free of diseases, includes beneficial endophytes and ensures a healthy start of a seedling. Focusing on the role of seed microbiota, their transmission and implications for producing healthier seeds as well as the relationship between the seed microbiome and primed plant resistance this book reveals the targeted use of the seed microbiome to enrich the soil biodiversity and its resilience and its resulting impact on plant health and yield. also explores the importance of nanotechnology in the development and production of crops for both improved plant production, and plant protection. It explores the different microbes that are vectored onto and within the seeds of both cultivated and non-cultivated plants, with an emphasis on the importance and roles of seed microbiomes in sustainable agriculture. It explains how to change seeds to increase microbiome vectoring; repairing damaged ones, and conserves seed microbiota. It also present seed microbiome roles for plant health and design effective microbiome engineering.

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