Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
- 2nd Edition - February 18, 2025
- Imprint: Academic Press
- Editor: Mahendra Rai
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 0 4 4 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 0 4 5 - 9
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the mo… Read more
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Request a sales quoteFighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.
The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.
The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.
- Presents four new chapters and special focus on plant-based nanoparticles
- Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development
- Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells, and more
- Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs
Natural product researchers, pharmacologists, pharmaceutical scientists and researchers involved in antimicrobial drug discovery, applied microbiology, infectious disease research and antibiotic resistance
- Title of Book
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Part I: General
- Chapter 1. Alternative antimicrobial approaches to fighting multidrug resistant infections
- Abstract
- Introduction
- Antimicrobial peptide antibiotics
- Bacteriocins and lantibiotics
- Bacterial interference
- Vaccine therapy
- Bacteriophage therapy
- Antimicrobial metals
- Medicinal grade honey
- Herb and plant extracts
- Major groups of antimicrobial compounds from plants
- Essential oils
- Maggot therapy
- Conclusions
- References
- Chapter 2. Multidrug resistance reversing potential of traditionally used medicinal plants
- Abstract
- Introduction
- Modulating action and reversal of bacterial resistance by plant extracts
- Conclusions
- References
- Chapter 3. Medicinal plants of Egypt for control of multidrug resistant microbes
- Abstract
- Introduction
- Conclusion
- AI disclosure
- References
- Chapter 4. Essential oils and extracts from medicinal plants of Nepal: combatting multidrug resistant microbes
- Abstract
- Introduction
- Essential oils and its market
- Essential oil-bearing plants of Nepal
- Industrial applications of essential oils
- Chemical constituents of essential oils in Pinaceae and Cuprassaceae
- Essential oils combatting multidrug resistant microbes
- Conclusion
- References
- Part II: Plant-derived antimicrobials against multidrug resistance
- Chapter 5. Potential of plant-derived compounds to reverse multidrug resistance in breast cancer cell lines
- Abstract
- Introduction
- Methodology
- Findings and analysis of literature
- Acylphloroglucinols
- Alkaloids
- Cumarins
- Diterpenoids
- Glycolipids
- Lignanes
- Limonoids
- Triterpenoids
- Steroids
- Pregnanes steroids
- Steroidal saponins
- Conclusion
- References
- Chapter 6. Natural agents from plants used against methicillin-resistant Staphylococcus aureus
- Abstract
- Introduction
- Plant extracts with anti-methicillin-resistant S. aureus effects
- Plant-derived molecules with anti-methicillin-resistant S. aureus activity
- Synergy between natural products and antibiotics used for the treatment of MRSA
- Other natural sources with anti-MRSA effects
- Small peptides
- Molecules derived from animals
- Bacteriocins
- Nucleotides
- Nanoparticles
- Conclusion
- References
- Chapter 7. Use of plants in the search for drugs to treat tuberculosis
- Abstract
- Introduction
- A brief history of tuberculosis as a globally significant disease
- Current epidemiology of tuberculosis and its treatment challenges
- Challenges faced in conventional tuberculosis treatment
- Exploring the potential of medicinal plants in the search for new treatments
- Mechanisms of action associated with the use of medicinal plants in the treatment of tuberculosis
- Stability of medicinal plant extracts for use in medicine
- Future perspectives
- References
- Chapter 8. Natural products and their perspectives in developing new leishmanicidal molecules
- Abstract
- Introduction
- Traditional antileishmanial drugs: Pentavalent antimonials, amphotericin B, and miltefosine
- Parasite resistance
- Natural products as sources of new antileishmanial compounds
- Conclusions and future perspectives
- References
- Chapter 9. Natural products with activity against Schistosoma species
- Abstract
- Introduction
- Conclusions
- Acknowledgments
- References
- Chapter 10. Botanical extracts for the prevention and treatment of multidrug resistant Staphylococcal infections
- Abstract
- Introduction
- Use of traditional botanical medicines as antibacterial agents
- Methicillin- and vancomycin-resistant Staphylococcus aureus
- Botanical extracts for treating methicillin-resistant Staphylococcus aureus and vancomycin-resistant Staphylococcus aureus infections
- Animal studies using botanical extracts for the treatment of methacillin-resistant Staphylococcus aureus infections
- Human studies using botanical extracts for treatment of methicillin-resistant Staphylococcus aureus infections
- The future of natural products for treating multidrug resistant Staphylococcus aureus infections
- References
- Chapter 11. Combining essential oils with antibiotics and other antimicrobial agents as a way of coping with multidrug resistant bacteria
- Abstract
- Introduction
- Essential oils as potential antibacterial agents
- Mechanism of action of essential oils on multidrug resistant bacteria
- Combination of essential oils with antibiotics and other antibacterial agents
- Future perspectives
- Conclusions
- References
- Chapter 12. Medicinal plants as alternative sources of therapeutics against multidrug resistant pathogenic microorganisms based on their antimicrobial potential and synergistic properties
- Abstract
- Introduction
- Antimicrobial agents from plant sources
- Plant extracts
- Essential oils and volatile oils
- Potential benefits, mechanisms, and effects of combination therapy in antimicrobial treatment
- Future directions: Synergistic therapy
- Measurement of synergy
- Experimental approaches
- Applications
- Food industry
- Cosmetic industry
- Pharmaceutical industry
- Oral care
- Future perspectives
- Conclusion
- References
- Chapter 13. Use of plant-derived extracts and bioactive compound mixtures against multidrug resistant bacteria affecting animal health and production
- Abstract
- Introduction
- Animal health and multidrug resistance
- Antibiotic growth promoters
- Alternatives to antibiotic growth promoters
- Conclusions
- References
- Chapter 14. Use of essential oils and their components and formulations against multidrug resistant bacteria
- Abstract
- Introduction
- Essential oil composition
- A perspective on the use of essential oils
- Bacterial cell targets and mode of action
- Mechanisms of antibiotic resistance
- Controlling multidrug resistant bacteria
- Synergistic action between essential oils and antibiotics
- Conclusions and future perspectives
- References
- Chapter 15. Natural products as alternative treatments for Candida species resistant to conventional chemotherapeutics
- Abstract
- Introduction
- Conventional antifungal drugs
- Antifungal activity of natural products obtained from plants
- Conclusions and future prospects
- Acknowledgment
- References
- Chapter 16. Plant products and essential oil therapy for treatment of new and emerging viruses
- Abstract
- Introduction
- Plant extracts and essential oils: a reservoir of antiviral agents
- Background
- Plant extracts and essential oils: an overview
- Bridging traditional wisdom with modern scientific inquiry
- Challenges and opportunities in adopting plant-based therapies
- The role of AYUSH, India, and similar efforts worldwide in handling challenges with herbal oils
- Conclusion and prospects
- Artificial intelligence disclosure
- References
- Part III: Nanotechnology-based tools against MDR
- Chapter 17. Plant-derived natural compounds delivery by nanoparticles to fight multidrug resistance
- Abstract
- Introduction
- Nanotechnology-based delivery systems containing plant derivatives as antimicrobials
- Polymeric nanoparticles and polymeric derivatives
- Metallic nanoparticles
- Conclusion
- References
- Chapter 18. Bioinspired green synthesis of nanoparticles by plants to fight against multidrug resistant microbes
- Abstract
- Introduction
- Multidrug resistance and its advances in microbes
- Green synthesis of nanoparticles by plants
- Factors affecting the bioinspired green synthesis of nanoparticles by plants
- Plant-mediated biogenic nanoparticles and antibiotics—a synergistic approach
- Mechanism of action of phyto-fabricated nanoparticles against multidrug resistance microbes
- Advantages and limitations of nanoparticles application against multidrug resistant microbes
- Future scope and prospects
- Conclusion
- Acknowledgment
- References
- Chapter 19. Confronting antifungal resistance: Innovative formulation strategies utilizing herbal extracts and essential oils against fungal challenge
- Abstract
- Introduction
- Antifungal resistance
- Antifungal herbal extracts and essential oils
- Novel formulation strategies for herbal extracts and essential oils
- Toxicity and safety of nanoformulations containing herbal extracts and essential oils
- Conclusion and future perspectives
- References
- Chapter 20. Unraveling the potential of curcumin-based nanoformulations: Advancing against multidrug resistance in lung cancer
- Abstract
- Introduction
- Mechanism of action of curcumin on non–small-cell lung cancer
- Regulation of cell cycle proliferation
- Induction of apoptosis
- Inhibition of metastasis and cell invasion
- Suppression of dysregulated signaling pathways
- Strategies to overcome curcumin’s low bioavailability
- Benefits of nanocurcumin
- Nanoformulation strategies to improve bioactivity of curcumin
- Lipid-based nanocurcumin
- Curcumin and lung cancer treatment
- Conclusion
- References
- Index
- Edition: 2
- Published: February 18, 2025
- Imprint: Academic Press
- No. of pages: 560
- Language: English
- Hardback ISBN: 9780443290442
- eBook ISBN: 9780443290459
MR
Mahendra Rai
Prof. Mahendra Rai is a UGC Basic Science Research Faculty Fellow and former Head of the Department of Biotechnology at Sant Gadge Baba Amravati University, India. He is currently a senior visiting professor in the Department of Chemistry at the Federal University of Piaui (UFPI), Brazil.
His areas of expertise include microbial biotechnology and nanobiotechnology, focusing on the green synthesis of metal nanoparticles using fungi and their applications as nanoantimicrobials against pathogenic microbes. His research is interdisciplinary, integrating microbial biotechnology with nanotechnology.
Professor Rai has received several prestigious awards, including the Father T.A. Mathias Award from the All India Association for Christian Higher Education and the Medini Award from the Government of India. He has participated in multiple international collaborations and has held visiting positions at various institutions, including the University of Geneva (Switzerland), Debrecen University (Hungary), and Nicolaus Copernicus University (Poland).
Affiliations and expertise
Senior Visiting Professor, Federal University of Piaui, BrazilRead Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components on ScienceDirect