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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • The Porphyrin Handbook, Volume 7

    • 1st Edition
    • Karl Kadish + 2 more
    • English

  • The Porphyrin Handbook, Volume 5

    • 1st Edition
    • Karl Kadish + 2 more
    • English

  • The Porphyrin Handbook, Volume 1

    • 1st Edition
    • Karl Kadish + 2 more
    • English

  • The Porphyrin Handbook

    • 1st Edition
    • Karl Kadish + 2 more
    • English
    Scientists in such fields as mathematics, physics, chemistry, biochemistry, biology, and medicine are currently involved in investigations of porphyrins and their numerous analogues and derivatives. Porphyrins are being used as platforms for the study of theoretical principles, as catalysts, as drugs, as electronic devices, and as spectroscopic probes in biology and medicine. The need for an up-to-date and authoritative treatise on the porphyrin system has met with universal acclaim amongst scientists and investigators. The Porphyrin Handbook represents a timely publication dealing with the recent chemistry, physics, biology, and medicine of porphyrins and related macrocycles. This publication will be a major reference source in this field for the new millennium.

  • Annual Reports on NMR Spectroscopy

    Cumulative Subject and Author Indexes Part II
    • 1st Edition
    • Volume 40
    • Graham A. Webb
    • English
    These indexes are valuable volumes in the serial, bringing together what has been published over the past 38 volumes. They include a preface by the editor of the series, an author index, a subject index, a cumulative list of chapter titles, and listings of contents by volume.

  • Chemistry and Biology

    • 1st Edition
    • Volume 53
    • English
    Alkaloids are a major group of natural products derived from a wide variety of organisms, which are used as medicinal and biological agents. This series is world-renowned as the leading compilation of current reviews of this vast field.Internationall... acclaimed for more than forty years, The Alkaloids , founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Biology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Analytical Profiles of Drug Substances and Excipients

    • 1st Edition
    • Volume 26
    • English
    Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.

  • Advances in Organometallic Chemistry

    Cumulative Subject and Contributor Indexes Including Tables of Contents, and a Comprehesive Keyword Index
    • 1st Edition
    • Volume 45
    • English
    A widely-acclaimed serial, Advances in Organometallic Chemistry contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic materials, and pharmaceuticals all depend on advancements in organometallic chemistry.

  • High Resolution NMR

    Theory and Chemical Applications
    • 3rd Edition
    • Edwin D. Becker
    • English
    High Resolution NMR provides a broad treatment of the principles and theory of nuclear magnetic resonance (NMR) as it is used in the chemical sciences. It is written at an "intermediate" level, with mathematics used to augment, rather than replace, clear verbal descriptions of the phenomena. The book is intended to allow a graduate student, advanced undergraduate, or researcher to understand NMR at a fundamental level, and to see illustrations of the applications of NMR to the determination of the structure of small organic molecules and macromolecules, including proteins. Emphasis is on the study of NMR in liquids, but the treatment also includes high resolution NMR in the solid state and the principles of NMR imaging and localized spectroscopy. Careful attention is given to developing and interrelating four approaches - steady state energy levels, the rotating vector picture, the density matrix, and the product operator formalism. The presentation is based on the assumption that the reader has an acquaintance with the general principles of quantum mechanics, but no extensive background in quantum theory or proficiency in mathematics is required. Likewise, no previous background in NMR is assumed, since the book begins with a description of the basic physics, together with a brief account of the historical development of the field. This third edition of High Resolution NMR preserves the "conversational" approach of the previous editions that has been well accepted as a teaching tool. However, more than half the material is new, and the remainder has been revised extensively. Problems are included to reinforce concepts in the book.

  • Annual Reports on NMR Spectroscopy

    Cumulative Subject and Author Indexes Part 1
    • 1st Edition
    • Volume 39
    • English
    These indexes are valuable volumes in the serial, bringing together what has been published over the past 38 volumes. They include a preface by the editor of the series, an author index, a subject index, a cumulative list of chapter titles, and listings of contents by volume.

  • Ions in Solution

    Basic Principles of Chemical Interactions
    • 1st Edition
    • J Burgess
    • English
    This outline of the principles and chemical interactions in inorganic solution chemistry delivers a course module in an area of considerable complexity. Problems with solutions and tutorial hints to test comprehension have been added as a feature to check readers' understanding and assist self-study. Exercises and projects are also provided to help readers deepen and extend their knowledge and understanding.

  • Theoretical Foundations of Molecular Magnetism

    • 1st Edition
    • Volume 1
    • Roman Boča
    • English
    Magnetochemistry is a highly interdisciplinary field that attracts the interest of chemists, physicists and material scientists. Although the general strategy of theoretical molecular magnetism has been in place for decades, its performance for extended systems of interacting magnetic units can be very complicated. Professor Boca's book treats the "mosaic" of the theoretical approaches currently used in the field. This book presents a review of the theoretical concepts of molecular magnetism. The first chapter of the book recapitulates the necessary mathematical background. An overview of macroscopic magnetic properties is then presented. Formulation of magnetic parameters and methods of their calculation are given, followed by a brief summary of magnetic behaviour. The core of the book deals with the temperature dependence of magnetic susceptibility for mononuclear complexes, dimers, and exchange-coupled clusters.This book will be particularly useful for those scientists and students working in the field of molecular magnetism who need to refer to a complete and systematic treatment of the mathematics of magneto-chemical theory.

  • Advances in Physical Organic Chemistry

    Cumulative Subject and Author Indexes for Part 2
    • 1st Edition
    • Volume 34
    • English
    The objective of the serial is to present considered reviews on the quantitative study of organic compounds and their behavior--physical organic chemistry in its broadest sense--in a manner accessible to a general readership.

  • Advances in Physical Organic Chemistry

    Cumulative Subject and Author Indexes for Part 1
    • 1st Edition
    • Volume 33
    • English
    The objective of this serial is to present considered reviews on the quantitative study of organic compounds and their behavior--physical organic chemistry in its broadest sense--in a manner accessible to a general readership.

  • Perspectives on Bioinorganic Chemistry

    • 1st Edition
    • Volume 4
    • R.W. Hay + 2 more
    • English
    The aim of this series is to provide authoritative reviews in the rapidly expanding area of bioinorganic chemistry. The series will present "state of the art" reviews covering the whole field of bioinorganic chemistry. The present volume is the fourth in the series and covers the topics: lithium in biology, the structure and function of ceroplasmin, rhenium complexes in nuclear medicine, the anti-HIV activity of macrocyclic polyamines and their metal complexes for dinuclear phosphoesterase enzymes.

  • Advances in Dendritic Macromolecules

    • 1st Edition
    • Volume 4
    • G.R. Newkome
    • English
    The series Advances in Dendritic Macromolecules aims to cover the synthesis and supramolecular chemistry of dendritic or cascade super-molecules as well as their less perfect hyperbranched cousins.The field of hyperbranched macromolecules, specifically dendrimers, has continued to expand at an amazing rate. The synthetic aspects, which were assumed to be over several years ago, have opened new avenues into the mesomolecular regime. The synthetic ingenuity of chemical artists has afforded new monomers and their diverse combinations to give rise to (poly)functionalized materials that embrace new supramolecular concepts in areas such as molecular recognition, assembly, encapsulation, and inclusion; catalysts; coatings; drug delivery systems; and in essence opens up the field of suprasupermolecular chemistry.In chapter 1 the synthesis of organometallic and related transition metal-cotaining dendrimers is summarized and their novel properties and useful applications are described. Chapter 2 covers work on the commercial poly(propylene imine)s, including the "dendritic box", dendrimer-based superamphiphiles, and unimolecular inverse micelles. The next chapter looks at aspects of chirality in dendritic systems and this is followed by a look inside dendrimers from a molecular topologist's point-of-view.

  • Advances in Sonochemistry

    • 1st Edition
    • Volume 5
    • T.J. Mason
    • English
    This is the fifth volume of Advances in Sonochemistry the first having been published in 1990. The definition of sonochemistry has developed to include not only the ways in which ultrsound has been harnessed to effect chemistry but also its uses in material processing. Subjects included range from chemical dosimetry to ultrasound in microbiology to ultrasound in the extraction of plant materials and in leather technology.

  • Annual Reports in Organic Synthesis 1999

    • 1st Edition
    • English
    One of the more difficult problems facing chemists today is that of "keeping up with the literature." Thus, an organized annual review of synthetically useful information would prove beneficial to nearly all organic chemists, both specialists and non-specialists in synthesis. Weintraub et al. are very successful in creating such an original review.

  • Direct Synthesis of Coordination and Organometallic Compounds

    • 1st Edition
    • A.D. Garnovskii + 1 more
    • English
    This book is devoted to the interaction between elemental metals and (in)organic ligands in different reaction conditions. Metals could be activated for further reactions as cryosynthesis, electrosynthesis and tribosynthesis, some of them with or without ultrasonic and microwave treatment. The kinetics of metal dissolution in various non-aqueous media is discussed in detail.Many methods are used nowadays to synthesize coordination compounds. Metal complexes are obtained mainly by the direct interaction of the components (the ligands and a source of the complex-forming metal), as a result of ligand and metal exchange, and under the conditions of template synthesis, which also include the method of nascent reagents. In these methods the source of the metal is either its salts or carbonyls. At the same time, it has long been known that coordination compounds may be obtained as a result of direct synthesis from zero-valent metals. Methods for the synthesis of complex compounds under the conditions of gas-phase reactions, oxidative dissolution of zero-valent metals in non-aqueous media, and in the solid phase have been developed. These methods have become the basis of a new field in synthetic chemistry - the direct synthesis of coordination and organometallic compounds from zero-valent metals.Particular aspects of the above problem have been described in a series of reviews and monographs. However, on the whole these main parts of the direct synthesis of metal complexes has not been dealt with in the review and monograph publications on coordination chemistry. So, the main objective of this book is to analyze, discuss and generalize the existing information in the area of direct reactions leading to the coordination and organometallic reactions.Some methods of direct synthesis have been developed in the former USSR (in particular, a lot of works on cryosynthesis, pioneered (1972-1973) and recent works on electrosynthesis) but, in spite of their novelty and/or wide applicability, they are practically unknown elsewhere due to the language barrier. Thus, another objective of this book is to acquaint the readers with the mentioned achievements.Every chapter contains the tables which describe all the reported data on direct reaction between metal atoms, metal particles or bulk metals with (in)organic ligans. There are some illustrations also (for example, the scheme of the reactor for gas-phase reaction between metal small particles and &bgr;-diketones)...

  • Progress in Heterocyclic Chemistry

    A Critical Review of the 1998 Literature Preceded by Two Chapters on Current Heterocyclic Topics
    • 1st Edition
    • Volume 11
    • G.W. Gribble + 1 more
    • English
    This volume of Progress in Heterocyclic Chemistry (PHC) is the eleventh annual review of the literature, covering the work published on most of the important heterocyclic ring systems during 1998, with inclusions of earlier materials as appropriate. In addition, this year there are three specialized reviews. Martine Demeunynck and Arnaud Tatibouët present recent chemistry of Tröger's Base in Chapter 1. Pedro Merino reviews the reactions of metalated heterocycles with carbonyl compounds in Chapter 2. John Joule summarizes the remarkable nucleophilic substitution chemistry on the indole five-membered ring in Chapter 3. The subsequent chapters deal with recent advances in the field of heterocyclic chemistry arranged by increasing ring size and with emphasis on synthesis and reactions. Due to the ever increasing amount of material to be surveyed, the authors were encouraged to provide selective and critical reviews of the more significant papers where space does not allow comprehensive coverage.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 44
    • English
    This widely-acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964. Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. Organometallic compounds range from species which are so reactive that they only have a transient existence at ambient temperatures to species which are thermally very stable. Organometallics are used extensively in the synthesis of useful compounds on both large and small scales. Industrial processes involving plastics, polymers, electronic materials, and pharmaceuticals all depend on advancements in organometallic chemistry.

  • Experiments in Catalytic Reaction Engineering

    • 1st Edition
    • Volume 124
    • J.M. Berty
    • English
    The science of catalytic reaction engineering studies the catalyst and the catalytic process in the laboratory in order to predict how they will perform in production-scale reactors. Surprises are to be avoided in the scaleup of industrial processes. The laboratory results must account for flow, heat and mass transfer influences on reaction rate to be useful for scaleup. Calculated performance based on these results must also be useful to maximization of profit and safety and minimization of pollution. To this end, information on products as well as byproducts and heat produced must be generated. If a sufficiently large database of knowledge is produced, optimization studies will be possible later if economic conditions change.The field of reaction engineering required new tools. For kinetic and catalyst testing, the most successful of these tools was the internal recycle reactor. Studies in recycle reactors can be made under well-defined conditions of flow and associated transfer processes, and close to commercial operation. The recycle reactor eliminates or minimizes the effect of transfer process, and allows the remaining ones to be known.Features of this book:• Provides insight into a field that is neither well understood nor properly appreciated.• Gives a deeper understanding of reaction engineering practice.• Helps avoid frustration and disappointment in industrial research. This book is short and clear enough to assist all members of the R&D and Engineering team, whether reaction engineers, or specialists in other fields. This is critical in this new age of computation and communication, when team members must each know at least something of their colleagues' fields. Additionally, many scientists in more exploratory or fundamental fields can use recycle reactors to study basic phenomena free of transfer interactions.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 74
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight to yield an understanding of how the chemistry drives the properties.Degenerat... ring transformations of heterocycles are classified as reactions in which a heterocyclic system is converted into the same heterocyclic system. This monograph covers an authoritative, comprehensive overview of a host of degenerate ring transformations in five- and six-membered heterocycles. It shows how by the use of 15N-labeled, 13C-labeled, or selectively substituted compounds these degenerate rign transformations can be discovered and how most of the results can be explained by the Addition Nucleophile, Ring Opening, and Ring Closure [ANRORC] mechanism. Another main topic of the monograph is the occurrence of degenerate ring transformations.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 38
    • English
    Over recent years, no other technique has grown to such importance as that of NMR spectroscopy. It is used in all branches of science where precise structural determination is required, and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a means for the specialist and non-specialist alike to become familiar with new applications of the technique in all branches of chemistry, including biochemistry, and pharmaceutics.Once again, the Annual Reports on NMR Spectroscopy represents the best work in the field, both in applied and theoretical NMR spectroscopy. The high calibre reports in Volume 38 show the wide biological and physical applications that benefit from this analytical technique.

  • Computational Molecular Biology

    • 1st Edition
    • Volume 8
    • J. Leszczynski
    • English
    This book covers applications of computational techniques to biological problems. These techniques are based by an ever-growing number of researchers with different scientific backgrounds - biologists, chemists, and physicists.The rapid development of molecular biology in recent years has been mirrored by the rapid development of computer hardware and software. This has resulted in the development of sophisticated computational techniques and a wide range of computer simulations involving such methods. Among the areas where progress has been profound is in the modeling of DNA structure and function, the understanding at a molecular level of the role of solvents in biological phenomena, the calculation of the properties of molecular associations in aqueous solutions, computationally assisted drug design, the prediction of protein structure, and protein - DNA recognition, to mention just a few examples. This volume comprises a balanced blend of contributions covering such topics. They reveal the details of computational approaches designed for biomoleucles and provide extensive illustrations of current applications of modern techniques.A broad group of readers ranging from beginning graduate students to molecular biology professions should be able to find useful contributions in this selection of reviews.

  • Thermodynamics

    Principles Characterizing Physical and Chemical Processes
    • 2nd Edition
    • Jurgen M. Honig
    • J. M. Honig
    • English
    This book provides a concise overview of thermodynamics, and is written in a manner which makes the difficult subject matter understandable. Thermodynamics is systematic in its presentation and covers many subjects that are generally not dealt with in competing books such as: Carathéodory's approach to the Second Law, the general theory of phase transitions, the origin of phase diagrams, the treatment of matter subjected to a variety of external fields, and the subject of irreversible thermodynamics.The book provides a first-principles, postulational, self-contained description of physical and chemical processes. Designed both as a textbook and as a monograph, the book stresses the fundamental principles, the logical development of the subject matter, and the applications in a variety of disciplines. This revised edition is based on teaching experience in the classroom, and incorporates many exercises in varying degrees of sophistication. The stress laid on a didactic, logical presentation, and on the relation between theory and experiment should provide a reader with a more intuitive understanding of the basic principles.Graduate students and professional chemists in physical chemistry and inorganic chemistry, as well as graduate students and professionals in physics who wish to acquire a more sophisticated overview of thermodynamics and related subject matter will find this book extremely helpful.

  • Heterogeneous Catalysis in Organic Chemistry

    • 1st Edition
    • Gerard V. Smith + 1 more
    • English
    The features of this book which will be of special interest to academic organic chemists are the introduction (Chapter 1), which presents a short course on the concepts and language of heterogeneous catalysis, covers organic reaction mechanisms of hydrogenation (Chapter 2), hydrogenolysis (Chapter 4), and oxidation (Chapter 6), a presents problems and solutions specific for running heterogeneous catalytic organic reactions in solution. These materials can supplement advanced chemistry courses. Most synthetic organic chemists use a variety of "protecting groups" which they attach to functional groups (reactive groups of atoms) while some reaction is being conducted on another part of the molecule. These protecting groups prevent reactions of the functional groups during other reactions and are removed later by a heterogeneous catalytic method called hydrogenolysis. One unique feature of this book, not found in other books on catalysis, is an exhaustive chapter (Chapter 4) on hydrogenolysis, which is dredged from the recent synthetic literature published by modern organic chemists. Academic organic chemists should find this chapter extremely useful and may wish to adopt the book as a supplement for advanced organic chemistry courses designed for seniors and for graduate students. It will also be useful for professors and their research groups engaged in synthetic organic chemistry. Many academic organic chemists are not aware of recent advances in heterogeneous enantioselective catalysis (Chapter 3) or in selective low temperature, liquid phase heterogeneous catalytic oxidations by hydrogen peroxide (Chapter 6). These specialty topics are timely and may be new to academic organic chemists and can be used to supplement their advanced courses. Several features of this book will also be of special interest to industrial chemists who are unfamiliar with heterogeneous catalysis. Many good organic chemists are hire by industry. They synthesize a new compound using standard organic synthetic techniques but are informed by their supervisor that they must convert some of their synthetic steps into heterogeneous catalytic steps. They may not have been exposed to heterogeneous catalysis and have few places to turn. This book offers them a crash course in heterogeneous catalysis as well as many examples of reactions and conditions with which they can start their search. Those industrial organic chemists already familiar with heterogeneous catalysis will find this book useful as a reference to many examples in the recent literature. They will find recent surface science discoveries correlated with heterogeneous catalysis or organic reactions and mechanistic suggestions designed to stimulate innovative nontraditional thinking about organic reactions on surfaces.

  • Molecular Structure Description

    The Electrotopological State
    • 1st Edition
    • Lemont B. Kier + 1 more
    • English
    The entire thrust of industrial drug research is now directed toward the use of predictive methods and strategies to reduce the number of compounds made and tested. Furthermore, these theoretical/computat... methods are increasingly part of a general approach to chemical problems. Among non-empirical structure indices, the electrotopological state of atoms in a molecule is a new paradigm, providing a descriptor of intermolecular interactions at submolecular sights that is easy to calculate and information-rich. One of the authors (Hall) has included the E-state in his widely used MOLCONN computer program. Tripos has incorporated this index as an optional module for structure-activity analyses using a new Web-based tool called CHEMenlighten.

  • Fundamental Chemical Kinetics

    An Explanatory Introduction to the Concepts
    • 1st Edition
    • M R Wright
    • English
    The unusual approach of this text gives final honours and post-graduate students a clear and explanatory account of one of the “harder” areas of physical chemistry. The author takes care to provide detailed verbal clarification of the concepts and their importance together with full explanations of the mathematical developments. Her explanations are an essential and vital feature of the text, which is scholarly, lucid and well-written with a combination of depth of coverage and clarity which helps students to work through on their own.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 32
    • English
    Volume 32 is proof again of the platform provided by Advances in Physical Organic Chemistry for some of the most interesting and diverse papers being produced today. Contributions by academic and industrial chemists give the volume a perspective useful to those working in both fields.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 73
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and most biological scientists. Written by established authorities in the field, the comprehensive review combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Applications of Kinetic Modelling

    • 1st Edition
    • Volume 37
    • G. Hancock + 1 more
    • English
    Volume 37 is concerned with the use and role of modelling in chemical kinetics and seeks to show the interplay of theory or simulation with experiment in a diversity of physico-chemical areas in which kinetics measurements provide significant physical insight. Areas of application covered within the volume include electro- and interfacial chemistry, physiology, biochemistry, solid state chemistry and chemical engineering.A leading contributor to this general area has been Professor W. John Albery, FRS, to whom the contributors and editors dedicate this book.

  • Biosensors: A Chinese Perspective

    • 1st Edition
    • Volume 4
    • Reinhard Renneberg + 1 more
    • English
    In this second volume of a sub-series dedicated to regional activities, eminent authorities form China in the field of biosensors provide an up-to-date overview of their laboratory's contribution, summarizing the primary research as it has appeared, possibly scattered, in the journal and conference literature and reflecting on their findings. This produces an innovative synthesis of such smaller research efforts into an overall perspective on the topic, which is difficult for the reader to glean from the multifarious original publications often available only in Chinese. There is latitude for the inclusion of detail that may have been excised from the original publication and for speculation on future possibilities. The net result is intense, yet highly readable accounts of the state of the art at this leading edge of analytical technology in this key region of the world.This is the first book in the English language summarizing biosensor and bioelectronics efforts in China.

  • Alkaloids: Chemical and Biological Perspectives

    • 1st Edition
    • Volume 13
    • S.W. Pelletier
    • English
    Volume 13 of this series presents five timely reviews of research on alkaloids such as new developments in the chemistry and biology of alkaloids from amphibian skins. It provides a synopsis and tabulation of the hundreds of alkaloids that have been detected, with an emphasis on occurrence, structure, dietary origins, and biological activity. Alkaloids containing the 1, 2, 3, 3a, 8, 8a - hexahydropyrrolo [2,3b] indole ring system and the cyclotryptamines are discussed. An exhaustive list of available structures is provided. The chemical and biological structures have been evaluated critically so as to identify existing errors and expose irregularities in appearance or biological function. In addition, attention is drawn to the possible implications of the accumulated knowledge related to the synthesis, occurrence, and biochemistry of this class of alkaloids.Recent work on alkaloids containing the comparatively non – basic pyrrole ring system is summarized. One of the chapters covers isolation, structure elucidation, biological activity, and selected chemical syntheses of certain pyrrole alkaloids.Recent developments in the chemistry of diterpenoid and norditerpenoid alkaloids occurring in Aconitum, Delphinium and Consolida genera of the Ranunculaceae family used in Chinese and Indian medicine are surveyed and the book ends with a focus on transition metal – catalyzed carbonylations as efficient and novel approaches to the construction of piperidine, izidine and quinazoline alkaloids, which occur in great numbers in nature.

  • Molecular Dynamics

    From Classical to Quantum Methods
    • 1st Edition
    • Volume 7
    • Perla Balbuena + 1 more
    • English
    The latest developments in quantum and classical molecular dynamics, related techniques, and their applications to several fields of science and engineering. Molecular simulations include a broad range of methodologies such as Monte Carlo, Brownian dynamics, lattice dynamics, and molecular dynamics (MD).Features of this book:• Presents advances in methodologies, introduces quantum methods and lists new techniques for classical MD• Deals with complex systems: biomolecules, aqueous solutions, ice and clathrates, liquid crystals, polymers• Provides chemical reactions, interfaces, catalysis, surface phenomena and solidsAlthough the book is not formally divided into methods and applications, the chapters are arranged starting with those that discuss new algorithms, methods and techniques, followed by several important applications.

  • Mathematics for Physical Chemistry

    • 2nd Edition
    • Robert G. Mortimer
    • English
    Mathematics for Physical Chemistry is the ideal textbook for upper-level undergraduates or graduate students who want to sharpen their mathematics skills while they are enrolled in a physical chemistry course. Solved examples and problems, interspersed throughout the presentation and intended to be worked when met in the text, encourage self-study by students new to the material. The author provides readers with a review of calculus and differential equations that will enable them to succeed in a physical chemistry course. An ideal reference text for practicing chemists as well.

  • Advances in Electron Transfer Chemistry

    • 1st Edition
    • Volume 6
    • P.S. Mariano
    • English
    It is clear that electron transfer chemisty is now one of the most active areas of chemical study. Advances in Electron Transfer Chemistry has been designed to allow scientists who are developing new knowledge in this rapidly expanding area to describe their most recent research findings. This volume will serve those interested in learning about current breakthroughs in this rapidly expanding area of chemical research.

  • Advances in Quantitative Structure-Property Relationships

    • 1st Edition
    • Volume 2
    • M. Charton + 1 more
    • English
    Quantitative structure property relationships (QSPR) have become a major method of chemical research. In the course of this development the field has suffered from fragmentation. Applications of QSPR are found in all major chemical disciplines including physical organic, physical, medicinal, agricultural, biological, enviromental, and polymer chemistry. Frequently workers in one area are unaware of parameterizations and models used in other ares which they might well find useful. The is a common thread which runs through these widely diverse areas. The basic principles, parameterizations and methodology are the same or similar throughout.The object of this series is to provide interesting and timely reviews covering all aspects of the field. It encourages the transfer of new methods, techniques, and parameterizations from the area in which they were developed to other areas that can make good use of them. In view of the widespread use of QSPR we believe that this is an important objective. This series will provide the cross-fertilization which is sorely needed.

  • Advances in Medicinal Chemistry

    • 1st Edition
    • Volume 4
    • B.E. Maryanoff + 1 more
    • English
    Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.

  • Pauling's Legacy

    Modern Modelling of the Chemical Bond
    • 1st Edition
    • Volume 6
    • Z.B. Maksic + 1 more
    • English
    Theory and experiment in chemistry today provide a wealth of data, but such data have no meaning unless they are correctly interpreted by sound and transparent physical models. Linus Pauling was a grandmaster in the modelling of molecular properties. Indeed, many of his models have served chemistry for decades and that has been his lasting legacy for chemists all over the world.The aim of this book is to put such simple models into the language of modern quantum chemistry, thus providing a deeper justification for many of Pauling's ideas and concepts. However, it should be stressed that many contributions to this work, written by some of the world's most prominent theoretical chemists, do not merely follow Pauling's footprints. By taking his example, they made bold leaps forward to overcome the limitations of the old models, thereby opening new scientific vistas.This book is an important contribution to the chemical literature. It is an almost obligatory textbook for postgraduate students and postdoctoral researchers in physical chemistry, chemical physics and advanced physical organic chemistry.

  • Coatings on Glass

    • 2nd Edition
    • H. Pulker + 1 more
    • English
    This is the second, revised edition of a book that has already proved invaluable to a wide range of readers. Written by a scientist for scientists and technical people, it goes beyond the subject matter indicated by the title, filling the gap which previously existed in the available technical literature. It includes a wealth of information for physicists, chemists and engineers who need to know more about thin films for research purposes, or who want to use this special form of solid material to achieve a variety of application-oriented goals.

  • Column Handbook for Size Exclusion Chromatography

    • 1st Edition
    • Chi-san Wu
    • English
    Column Handbook for Size Exclusion Chromatography is the first comprehensive reference to provide everything one needs to know about commercial analytical and preparative columns for size exclusion and gel filtration chromatography (SEC and GFC). SEC is now widely used as a quality assurance method in the polymer industry (both synthetic and biopolymers) to determine molecular weight and molecular weight distribution. The Handbook contains contributions from every column manufacturer around the world and from many experienced column users. It covers the technology, characterization, application, evaluation, maintenance, and quality control of analytical and preparative columns for SEC and GFC. Also included are columns for two closely related techniques, hydrodynamic chromatography and high osmotic pressure chromatography.

  • Comprehensive Supramolecular Chemistry, Volume 5

    Supramolecular Reactivity and Transport: Bioinorganic Systems
    • 1st Edition
    • K.S. Suslick
    • English
    In this volume, an overview of the expanse of bioinorganic systems that involve supramolecular chemistry has been assembled. It commences with introductions to the supramolecular aspects of bioinorganic synthetic analogues and of metalloprotein structure and function. From there, a range of topics involving diverse metallobiomolecules (proteins, nucleic acids, and their synthetic analogues) are developed.

  • Comprehensive Supramolecular Chemistry, Volume 3

    Cyclodextrins
    • 1st Edition
    • J. Szejtli + 1 more
    • English
    The total number of papers, conferences, abstracts and patents dedicated to cyclodextrins by the end of 1995 will be about 12,000 in number. This vast number of publications deals with the chemistry (structure, chemical reactivity), biology (enzymology, metabolism, toxicity, direct therapeutic effects), inclusion complex forming capacity and its consequences, and industrial utilization of cyclodextrins (in drugs, foods, cosmetics, chromatography, catalysis biotechnology, diagnostics etc) in unlimited numbers of products and technologies.This volume pulls all this information together, covering the chemistry, biology and industrial application of cyclodextrins as molecular encapsulating agents in research methods, analytical procedures, industrial technologies and products.

  • Comprehensive Supramolecular Chemistry, Volume 6

    Solid-State Supramolecular Chemistry: Crystal Engineering
    • 1st Edition
    • D.D. MacNicol + 2 more
    • English
    This volume, containing 27 chapters, provides a state-of-the-art account of the chemistry of solid-state supramolecular systems. Following a valuable introductory chapter reviewing important general principles, the coherent coverage is structured in the form of a series ofcontributions all written by experts in the respective areas comprehensively described. Throughout the volume, emphasis is placed not only on the design and structure of new hostsystems but also on practical applications of these novel materials in real chemical situations. The crystal engineering methods described relate to the synthesis of both organic and inorganictailor-made hosts. Also the reader is presented with highly relevant descriptions ofthermodynamic and kinetic considerations germane to the formation crystalline inclusioncompounds. The final chapter gives a fascinating account of the self-organisation of moleculesin two and three dimensions, crucially important to any process of crystal nucleation.

  • Advances in Cycloaddition

    • 1st Edition
    • Volume 5
    • Michael Harmata
    • English
    The development and application of cycloaddition methodology continues to be at the forefront of research in synthetic organic chemistry. This volume begins with a review of methods available for the synthesis of seven-membered rings and is followed with work on metal-catalyzed cycloadditions. There is then an update on the cycloaddition chemistry of 2-pyrone, and then a unique application of photocycloaddition is detailed. The final chapter is a discussion of the latest explorations of the reaction of rhodium-stabilized vinyl carbenoids with dienes.

  • Reaction Kinetics and the Development of Catalytic Processes

    Proceedings of the International Symposium, Brugge, Belgium, April 19-21, 1999
    • 1st Edition
    • Volume 122
    • G.F. Froment + 1 more
    • English
    The symposium "Reaction Kinetics and the Development of Catalytic Processes" is the continuation of the very successful International Symposium "Dynamics of Surfaces and Reaction Kinetics in Heterogeneous Catalysis", held in September 1997 in Antwerp, Belgium. These proceedings contain a unique series of top level plenary lectures mainly focused on• the dynamics of catalytic surfaces• the interaction of the reacting molecules with the solid catalyst• the elementary steps of reaction pathways and molecular kinetics.Surface science techniques, molecular modeling, transient kinetic studies, sophisticated and specific reactors are included to a growing extent in the kinetic modeling and the development of catalytic processes. How this is practiced today and how it will evolve in the coming years, and what benefit can be expected for a more fundamentally based approach is the aim of the symposium.

  • Thermal Decomposition of Ionic Solids

    Chemical Properties and Reactivities of Ionic Crystalline Phases
    • 1st Edition
    • Volume 86
    • A.K. Galwey + 1 more
    • English
    The principal objective of this book is to stimulate interest in research that will extend available theory towards a greater understanding of the steps involved in solid-state decompositions and the properties of solids that control reactivities. Much of the activity in this field has been directed towards increasing the range of reactants for which decomposition kinetic data is available, rather than extending insights into the fundamental chemistry of the reactions being studied. The first part of the book (Chapters 1-6) is concerned with theoretical aspects of the subject. The second part (Chapters 7-17) surveys groups of reactions classified by similarities of chemical composition. The final Chapter (18) reviews the subject by unifying features identified as significant and proposes possible directions for future progress.Studies of thermal reactions of ionic compounds have contributed considerably to the theory of solid-state chemistry. Furthermore, many of these rate processes have substantial technological importance, for example, in the manufacture of cement, the exploitation of ores and in the stability testing of drugs, explosives and oxidizing agents. Despite the prolonged and continuing research effort concerned with these reactions, there is no recent overall review. This book is intended to contribute towards correcting this omission. The essential unity of the subject is recognized by the systematic treatment of reactions, carefully selected to be instructive and representative of the subject as a whole. The authors have contributed more than 200 original research articles to the literature, many during their 25 years of collaboration.Featur... of this book:• Gives a comprehensive in-depth survey of a rarely-reviewed subject.• Reviews methods used in studies of thermal decompositions of solids.• Discusses patterns of subject development perceived from an extensive literature survey.This book is expected to be of greatest value and interest to scientists concerned with the chemical properties and reactions of solids, including chemists, physicists, pharmacists, material scientists, crystallographers, metallurgists and others. This wide coverage of the literature dealing with thermal reactions of solids will be of value to both academic and industrial researchers by reviewing the current status of the theory of the subject. It could also provide a useful starting point for the exploitation of crystalline materials in practical and industrial applications. The contents will also be relevant to a wide variety of researchers, including, for example, those concerned with the stabilities of polymers and composite materials, the processing of minerals, the shelf-lives of pharmaceuticals, etc.

  • Flow Analysis with Atomic Spectrometric Detectors

    • 1st Edition
    • Volume 9
    • A. Sanz-Medel
    • English
    Flow Analysis (FA) offers a very convenient and fast approach to enhance and automate 'preliminary steps' of analysis (sample dissolution, pretreatments, preconcentrations, etc.) for atomic spectrometric detectors (ASD). Moreover, flow manifolds can ease the well-known problem of sample introduction/present... to atomisers or even expand the classical scope of atomic/elemental information, characterizing atomic spectrometry, into the realm of molecules and metal-compounds analysis (e.g. by resorting to coupled separation techniques). All these facts could explain both the extraordinary interest for research and the great importance for practical problem-solving achieved nowadays by FA-ASD.On the threshold of the new millennium when plasma emission and mass spectrometry are so important and popular, the editor considered it timely to produce a book which covers all present atomic detectors and techniques where FA has been or can be advantageously employed. The book has been conceived in three separate parts:Part I gives the fundamental, instrumentation and potential of FIA as a most versatile sample presentation/introdu... system for atomic spectrometry.Part II provides a modern account of fundamentals, possibilities and applications offered by flow analysis to atomic spectrometry for on-line sample pretreatments, separations and preconcentrations.Pa... III deals with applications of FA-ASD combinations to analytical problem-solving in most varied fields and situations.This monograph integrates the most popular aspects of FIA, its new developments for sample on-line treatments and on-line non-chromatographic and chromatographic separations (all typical 'flow analysis') in connection with all branches of analytical atomic spectrometry. Thus, academics, researchers and routine users of analytical atomic spectrometry will find this book invaluable.

  • Advances in Asymmetric Synthesis

    • 1st Edition
    • Volume 3
    • Alfred Hassner
    • English
    Enantioselective synthetic methods are not only in the forefront of chemical and pharmaceutical research but activity in this area is constantly increasing. It is stimulated by the urgency to obtain drugs or compounds of medicinal interest as single anantiomers, and the keeness to synthesize natural products in nonracemic form. This volume presents seven chapters from pioneers and authorities in this rapidly expanding field.

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