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Elsevier

Books in Life sciences

  • Safety Issues in Beverage Production

    Volume 18: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Safety Issues in Beverage Production, Volume 18, in the Science of Beverages series, offers a multidisciplinary approach to the complex issues emerging in the beverage industry. The book is broad in coverage and provides the necessary foundation for a practical understanding of the topics that includes recent scientific industry developments that are explained to improve awareness, educate and create communication. The latest trends in legislation, safety management and novel technologies specific to beverages are discussed. This resource is ideal as a practical reference for scientists, engineers and regulators, but can also be used as a reference for courses.

  • Difficult to Diagnose Rare Diffuse Lung Disease

    • 1st Edition
    • Alexander V. Averyanov
    • English
    Difficult to Diagnose Rare Diffuse Lung Disease presents the theoretical basis and practical aspects of differential diagnoses of rare lung diseases with the use of new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region. Each chapter describes signs and symptoms of the disease and its typical and atypical manifestations. The book contains full color illustrations, including high-resolution histological microphotographs, CT-scans and confocal laser endomicroscopy images. In combination, these elements make this book an invaluable reference and guide for pulmonary researchers, pulmonologists, radiologists, and pathologists who wish to broaden their spectrum of knowledge in rare lung diseases.

  • Nanomycotoxicology

    Treating Mycotoxins in the Nano Way
    • 1st Edition
    • Mahendra Rai + 1 more
    • English
    Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge.

  • Cellular Nutrient Utilization and Cancer

    • 1st Edition
    • Volume 347
    • English
    Cellular Nutrient Utilization and Cancer, Volume 347 in the International Review of Cell and Molecular Biology (IRCMB) series maintains a high standard by publishing invited articles on timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include Sulfur metabolism and cancer, The interplay of genetic drivers of cancer and cellular nutrients to support oncogenesis, The diet’s impact on nutrient availability for cancer cells, Nutrients as determinants of redox balance in cancer, The role of dietary lipids in colon cancer pathogenesis, The influence of diet on nutrient utilization by cancer cells and immune-surveillance, and more.

  • Physics of Biological Action and Perception

    • 1st Edition
    • Mark L. Latash
    • English
    Physics of Biological Action and Perception helps researchers interested in exploring biological motor control from a physics or alternative viewpoint perspective. The book introduces the idea of parametric control as a distinguishing feature of living systems. Sections cover how the CNS creates stable percepts based on fuzzy and continuously changing signals from numerous receptors and the variable processes related to ongoing actions. The author also develops the idea of control with referent coordinates to stability of salient variables in fields typically united under the label of "cognition." Examples of this include communication (how the gist of a message is preserved despite variability of phrases), thought processes (how one can solve a mental problem via different logical routes), and playing chess (how one selects an optimal move given a position on the board). The book is written for researchers, instructors, clinicians and other professionals in all the fields related to biological movement and perception.

  • How to Integrate Quality by Efficient Design (QbED) in Product Development

    • 1st Edition
    • Bhavishya Mittal
    • English
    The development of a robust drug product requires juggling many competing priorities such as overcoming scientific challenges, following regulatory requirements, and managing business-related concerns. Unfortunately, despite large resources spent on R&D, multifactor productivity of pharmaceuticals is on the decline for several years now. Because of this business reality, pharmaceutical companies have seen a notable change in the traditional operating model and footprint over the past couple of decades. Outsourcing, in particular, has emerged as a successful business model for many pharmaceutical companies looking for ways to strategically increase their R&D capabilities and to augment their in-house resources. How to Integrate Quality by Efficient Design (QbED) in Product Development bridges the gap between theory and practice when it comes to strategic decision-making in a pharmaceutical research scenario. This book will introduce the concept of QbED and focus on various aspects such as patient-centric product designs, platform-based manufacturing technologies, business acuity, and regulatory strategies to balance the challenges in outsourcing with the need for strategic and statistically sound experiments rooted in good science. Detailed discussions will cover pharmaceutical business models, regulatory approval process, quality by design (QbD), business analytics, and manufacturing excellence specifically for small molecules and solid oral dosage forms. With the addition of case studies, flowcharts, diagrams, and data visualizations, How to Integrate Quality by Efficient Design (QbED) in Product Development will be a practical reference to help professionals working in the area of pharmaceutical drug development, strategy, and outsourcing management.

  • Molecular Nutrition

    Vitamins
    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.

  • Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia

    • 1st Edition
    • M. Khalid Mojadidi + 2 more
    • English
    Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

  • Management Strategies for Sustainable Cattle Production in Southern Pastures

    • 1st Edition
    • Monte Rouquette Jr. + 1 more
    • English
    Management Strategies for Sustainable Cattle Production in Southern Pastures is a practical resource for scientists, students, and stakeholders who want to understand the relationships between soil-plant interactions and pasture management strategies, and the resultant performance of cow-calf and stocker cattle. This book illustrates the importance of matching cattle breed types and plant hardiness zones to optimize cattle production from forages and pastures. It explains the biologic and economic implications of grazing management decisions made to improve sustainability of pastures and cattle production while being compliant with present and future environmental concerns and cattle welfare programs.

  • Functional Food Ingredients from Plants

    • 1st Edition
    • Volume 90
    • English
    Functional Food Ingredients from Plants, Volume 90, the latest release in the Advances in Food and Nutrition Research series, provides updated knowledge about nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet to reduce disease risk and optimize health. Updates to this release include sections on Natural antioxidants of plant origin, Dietary fiber sources, The impact of molecular interactions with phenolic compounds on food polysaccharides functionality, Plant phenolics as functional ingredients, Pigments and vitamins from plants as functional ingredients, Glucosinolates fate from plants to consumer, and more.

  • Principles of Bone Biology

    • 4th Edition
    • John P. Bilezikian + 3 more
    • English
    Preface from the first edition (1996): "The world of modern science is undergoing a number of spectacular events that are redefining our understanding of ourselves. As with any revolution, we should take stock of where we have been, where we are, and where we are going. Our special world of bone biology is participating in and taking advantage of the larger global revolution in modern science… we assembled experts from all over the world and asked them to focus on the current state of knowledge and the prospects for new knowledge in their area of expertise. To this end,　Principles of Bone Biology　was conceived." - John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan Praise for the previous edition: "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine For over two decades, "Big Gray" has been the go-to repository of knowledge in the disciplines related to bone and mineral metabolism. The fourth edition is a must-have for students new to the field; young investigators at the graduate or postgraduate level beginning their research careers; established scientists who need to keep up with the changing nature of the field, looking to enrich their own research programs, or who are changing their career direction; clinicians who want ready access to up-to-date relevant basic science. This new edition builds on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Principles of Bone Biology, Fourth Edition provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. Bone research continues to generate enormous attention, due to the broad public health implications of osteoporosis and related bone disorders. This classic, fully updated, two volume reference is designed for anyone involved in the study of bone biology.

  • Meat Quality Analysis

    Advanced Evaluation Methods, Techniques, and Technologies
    • 1st Edition
    • Ashim Kumar Biswas + 1 more
    • English
    Meat Quality Analysis: Advanced Evaluation Methods, Techniques, and Technologies takes a modern approach to identify a compositional and nutritional analysis of meat and meat products, post-mortem aging methods, proteome analysis for optimization of the aging process, lipid profiles, including lipid mediated oxidations, meat authentication and traceability, strategies and detection techniques of potential food-borne pathogens, pesticide and drug residues, including antimicrobial growth promoters, food preservatives and additives, and sensory evaluation techniques. This practical reference will be extremely useful to researchers and scientists working in the meat industry, but will also be valuable to students entering fields of meat science, quality and safety.

  • Coronary Calcium

    A Comprehensive Understanding of Its Biology, Use in Screening, and Interventional Management
    • 1st Edition
    • Aloke Virmani Finn
    • English
    Coronary Calcium: A Comprehensive Understanding of Its Biology, Use in Screening, and Interventional Management provides a comprehensive update on the current understanding of the significance of coronary artery calcification, showing the connection to the development of advanced atherosclerosis that will lead to better risk evaluations. Coverage includes information on the basic science behind the development of coronary calcium in atherosclerotic lesions, the pathology of calcified coronary lesions in humans, its differential development by race, and its relationship to plaque progression. Computed tomography is also covered to show the significance of coronary calcium for risk prediction and the potential role of various pharmacologic interventions. Each chapter contains summaries with salient and important points, making this book perfect for researchers and physicians interested in the field of vascular calcification.

  • Clinical Simulation

    Education, Operations and Engineering
    • 2nd Edition
    • Gilles Chiniara
    • English
    Clinical Simulation: Education, Operations and Engineering, Second Edition, offers readers a restructured, comprehensive and updated approach to learn about simulation practices and techniques in a clinical setting. Featuring new and revised chapters from the industry’s top researchers and educators, this release gives readers the most updated data through modern pedagogy. This new edition has been restructured to highlight five major components of simulation education, including simulation scenarios as tools, student learning, faculty teaching, necessary subject matter, and the learning environment. With clear and efficient organization throughout the book, users will find this to be an ideal text for students and professionals alike.

  • Effects of Lifestyle on Men's Health

    • 1st Edition
    • Faysal A. Yafi + 1 more
    • English
    Effects of Lifestyle on Men’s Health provides an evidence-based review of the effects of modifiable risk factors such as sleep, diet, stress and exercise on various elements of men’s health, notably sexual function, urinary function and cancer prevention and detection. Content highlights the most up-to-date basic and clinical information available, along with future research directions. Each chapter provides an easy to reference bullet point style summary to highlight the salient take-home messages from each section. Researchers and clinicians alike can use this book as a reference point for all matters related to lifestyle and men’s health.

  • Virus Entry

    • 1st Edition
    • Volume 104
    • Thomas Mettenleiter + 2 more
    • English
    Virus Entry, Volume 104, the latest release in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on plant virus cell-to-cell entry, plant virus entry via insect transmission, VSV/Rabies virus entry, Papovavirus entry, New approaches to study fusion proteins, Hantavirus receptors, Gamma Herpesvirus entry, and many other interesting topics.

  • Nucleic Acids as Gene Anticancer Drug Delivery Therapy

    • 1st Edition
    • Loutfy H. Madkour
    • English
    Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research.

  • Genomic and Precision Medicine

    Infectious and Inflammatory Disease
    • 3rd Edition
    • Geoffrey S. Ginsburg + 3 more
    • English
    Genomic and Precision Medicine: Infectious and Inflammatory Disease, Third Edition, provides current clinical solutions on the application of genome discovery on a broad spectrum of disease categories in IMD - including asthma, obesity and multiple sclerosis. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies, along with information on a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

  • Quality Control in the Beverage Industry

    Volume 17: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Quality Control in the Beverage Industry, volume 17, in the Science of Beverages series, presents a detailed account of the most common aspects and challenges relating to quality control. It covers the latest global trends in how to improve beverages using assessment tools, authenticity approaches and novel quality control technologies. The book presents a great, hands on approach for anyone who needs to understand the big picture regarding analytical methods. Topics covered include safety, the economic impacts of contamination, and detection techniques.

  • Cell and Tissue Destruction

    Mechanisms, Protection, Disorders
    • 1st Edition
    • Jurgen Arnhold
    • English
    Cell and Tissue Destruction: Mechanisms, Protection, and Disorders provides an overview of the main mechanisms responsible for degradation in human beings and summarizes important strategies to counter these mechanisms. This book details the properties and limits of protective mechanisms, along with disturbances to systematic physiological functions. It provides examples of disease states resulting from the limits of protective systems. Three sections consider the physical and chemical reasons for destruction in living systems, protection against cytotoxic components, and the development of pathologic states. This book provides neuroscientists, cancer researchers and physicians with robust, overall coverage of the interrelated processes involved in cell and tissue destruction in living structures, and concomitant protective mechanisms and their limitations.

  • Fundamentals of Molecular Structural Biology

    • 1st Edition
    • Subrata Pal
    • English
    Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche.

  • Advances in Biomechanics and Tissue Regeneration

    • 1st Edition
    • Mohamed H. Doweidar
    • English
    Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics.

  • Purification and Characterization of Secondary Metabolites

    A Laboratory Manual for Analytical and Structural Biochemistry
    • 1st Edition
    • Thomas E. Crowley
    • English
    Purification and Characterization of Secondary Metabolites: A Laboratory Manual for Analytical and Structural Biochemistry provides students with working knowledge of the fundamental and advanced techniques of experimental biochemistry. Sections provide an overview of the microbiological and biochemical methods typically used for the purification of metabolites and discuss the biological significance of secondary metabolites secreted by three diverse species of bacteria. Additionally, this lab manual covers the theory and practice of the most commonly-used techniques of analytical biochemistry, UV-vis and IR spectrophotometry, high-performance liquid chromatography, mass spectrometry, X-ray crystallography and nuclear magnetic resonance, and how to evaluate and effectively use scientific data. Instructors will find this book useful because of the modular nature of the lab exercises included. Written in a logical, easy-to-understand manner, this book is an indispensable resource for both students and instructors.

  • Ultraviolet LED Technology for Food Applications

    From Farms to Kitchens
    • 1st Edition
    • Tatiana Koutchma
    • English
    Ultraviolet LED Technology for Food Applications: From Farms to Kitchens examines the next wave in the LED revolution and its ability to bring numerous advantages of UVC disinfection. As UVC LED-based light fixtures will become the driving force behind wider adoption, with potential use in the treatment of beverages, disinfection of food surfaces, packaging and other food contact and non-contact surfaces, this book presents the latest information, including LEDs unique properties and advantages and the developments and advances made in four areas of application, including produce production and horticulture, post-harvest and post processing storage, safety and point-of-use applications. Alternative opportunities to current practices of food production and processing that are more sophisticated and diverse are being intensively investigated in recent decades, things like Ultraviolet light (UV) irradiation. The effects of UVC LEDs against bacteria, viruses and fungi already have been demonstrated and reported, along with the first applications for disinfection of air, water and surface made for the "point-of-use" integration.

  • Encyclopedia of Microbiology

    • 4th Edition
    • Thomas M. Schmidt
    • English
    Encyclopedia of Microbiology, Fourth Edition, Five Volume Set gathers both basic and applied dimensions in this dynamic field that includes virtually all environments on Earth. This range attracts a growing number of cross-disciplinary studies, which the encyclopedia makes available to readers from diverse educational backgrounds. The new edition builds on the solid foundation established in earlier versions, adding new material that reflects recent advances in the field. New focus areas include `Animal and Plant Microbiomes’ and ‘Global Impact of Microbes`. The thematic organization of the work allows users to focus on specific areas, e.g., for didactical purposes, while also browsing for topics in different areas.

  • Epidermal Stem Cell Niche

    • 1st Edition
    • Volume 3
    • Mirna Perez-Moreno
    • English
    Advances in Stem Cells and Their Niches, Volume Three, comprises a compilation of the latest findings on our understanding of skin biology. It extends the current knowledge on skin stem cells and provides in-depth discussions on their unique settings, niches and properties. Chapters in this new release include The biophysical regulation of epidermal fate and function, Epidermal stem cell lineages, Hair shaft progenitors that create a niche for hair pigmentation, Dermal papilla cells control of hair follicle growth and pigmentation, Molecular mechanisms regulating the hair follicle niche, Dermal fibroblasts and their niches and interactions with epidermal stem cells.

  • Trends in Beverage Packaging

    Volume 16: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Trends in Beverage Packaging, volume 16 in the Science of Beverages series, presents an interdisciplinary approach that provides a complete understanding of packaging theories, technologies and materials. This reference offers a broad perspective regarding current trends in packaging research, quality control techniques, packaging strategies and current concerns in the industry. Consumer demand for bottled and packaged beverages has increased, and the need for scientists and researchers to understand how to analyze quality, safety and control are essential. This is an all-encompassing resource for research and development in this flourishing field that covers everything from sensory and chemical composition, to materials and manufacturing.

  • Theranostic Approach for Pancreatic Cancer

    • 1st Edition
    • Ganji Purnachandra Nagaraju + 1 more
    • English
    Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer.

  • Metabolic Disorders and Shen in Integrative Cardiovascular Chinese Medicine

    Volume 7
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Metabolic Disorders and Shen in Integrative Cardiovascular Medicine, volume seven in the Integrative Cardiovascular Chinese Medicine series, presents the connection between metabolic diseases that affect the cardiovascular system and mental health through both Chinese and Western medicine explanations. Sections discuss the etiology of metabolic disorders of blood sugar disorders, lipid disorders, inflammatory disorders and shen, the clinical significance and differentiations in both Western and Chinese medicine, and prescriptions and the medicated diet, including main acupoints, remedies and medicines used in Western and Chinese medicine and the combination of medicinal herbs and food for Chinese diet therapy. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base that not only guides clinical practice, but also encourages collaboration between Chinese and Western medicine practitioners.

  • Nutraceuticals and Natural Product Pharmaceuticals

    • 1st Edition
    • Charis M. Galanakis
    • English
    Nutraceuticals and Natural Product Pharmaceuticals analyzes the nutraceutical and pharmaceutical research published over the last decade, paying particular attention to applications and recovery effects. The book emphasizes the great need for both nutritionists and pharmacologists to understand how these drugs can benefit human health. Topics explore innovative sources, bioavailability, pharmacokinetics, translating novel pathways and mechanisms of action into their clinical use, personalized nutrition and natural product medicine, the convergence between nutraceuticals and western medicine, interactions between drugs, nutrients, the microbiome and lifestyles, industrial applications and commercialization, metabolomics, nano-delivery systems and function, and more. Nutritionists and pharmacists working with natural products, food scientists, nutrition researchers and those interested in the development of innovative products, nutraceuticals, pharmaceuticals and functional foods are sure to benefit from this thorough resource.

  • High-Density Integrated Electrocortical Neural Interfaces

    Low-Noise Low-Power System-on-Chip Design Methodology
    • 1st Edition
    • Sohmyung Ha + 3 more
    • English
    High-Density Integrated Electrocortical Neural Interfaces provides a basic understanding, design strategies and implementation applications for electrocortical neural interfaces with a focus on integrated circuit design technologies. A wide variety of topics associated with the design and application of electrocortical neural implants are covered in this book. Written by leading experts in the field— Dr. Sohmyung Ha, Dr. Chul Kim, Dr. Patrick P. Mercier and Dr. Gert Cauwenberghs —the book discusses basic principles and practical design strategies of electrocorticography... electrode interfaces, signal acquisition, power delivery, data communication, and stimulation. In addition, an overview and critical review of the state-of-the-art research is included. These methodologies present a path towards the development of minimally invasive brain-computer interfaces capable of resolving microscale neural activity with wide-ranging coverage across the cortical surface.

  • New Techniques for Management of ‘Inoperable’ Gliomas

    • 1st Edition
    • Michael E. Sughrue + 1 more
    • English
    New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients.

  • Methods in Kidney Cell Biology Part A

    • 1st Edition
    • Volume 153
    • English
    Methods in Kidney Cell Biology, Volume 153, represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, and clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more.

  • Lipid-Based Nanostructures for Food Encapsulation Purposes

    Volume 2 in the Nanoencapsulation in the Food Industry series
    • 1st Edition
    • Volume 2
    • English
    Lipid-Based Nanostructures for Food Encapsulation Purposes, Volume Two in the Nanoencapsulation in the Food Industry series, reviews recent studies on the formulation and evaluation of different categories of lipid-based nano-carriers and discusses how lipid nanoencapsulation is a feasible technology for the food industry. This book covers nano-emulsions, nano-liposomes, nanostructured lipid carriers and surfactant nanoparticles. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title is of great value to those engaged in the various fields of nanoencapsulation.

  • Cancer Immunotherapy

    • 1st Edition
    • Volume 164
    • David B. Teplow
    • English
    Cancer Immunotherapy, Volume 165 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to different approaches to cancer immunotherapy, with this release focusing on TNFR2 in cancer immunology and immunotherapy, From the Hellstrom paradox towards cancer cure, CAR T-cell treatment of T-cell malignancy , Immunotherapy of pancreatic cancer, Cancer stem cell immunology/immunothe... Cytokine release syndrome, Tumor cell-based mechanisms of resistance to immune attack, and Mushroom compounds in cancer immunotherapy.

  • Neurophysiologie

    De la physiologie à l'exploration fonctionnelle - avec simulateur informatique
    • 3rd Edition
    • Jean-François Vibert + 8 more
    • French
    Ce manuel expose les connaissances actuelles en neurophysiologie dans une optique clinique. Il présente de manière simple et claire le fonctionnement du système nerveux et les conséquences cliniques de ses dysfonctionnements.À partir de leur expérience, les auteurs, médecins enseignants-chercheu... décrivent les méthodes physiologiques d’exploration du système nerveux normal et pathologique, et les résultats que l’on peut en attendre. Le lecteur acquiert ainsi les connaissances indispensables à la prescription et à l’interprétation de tels examens. L’abondante iconographie en couleurs illustre avec justesse un texte didactique et complet.Cette 3e édition propose une révision approfondie de l’ensemble des contenus en optimisant l’aspect et l’approche pédagogique :• les parties sur les explorations fonctionnelles d’une part et celles sur les troubles et la clinique d’autre part sont désormais harmonisées et individualisées dans des encarts ;• de nouvelles illustrations viennent enrichir l’iconographie ;• par ailleurs, le lecteur bénéficie d’un accès en ligne à toute l’iconographie de l’ouvrage (260 illustrations), grâce à une banque d’images ;• de nombreux exercices pratiques à réaliser à l’aide d’un simulateur informatique, sont également accessibles en ligne, afin d’appréhender aisément le fonctionnement des neurones et le comportement des réseaux de neurones.Neurophysio... est destiné aux étudiants en médecine, en sciences paramédicales et STAPS. Sa lecture constituera également une aide pour les médecins et les autres professionnels de santé.

  • Opioid Hormones

    • 1st Edition
    • Volume 111
    • Gerald Litwack
    • English
    Vassopressin, Volume 111, the latest release in the Vitamins and Hormones series, first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

  • Neuropsychotherapeutics

    • 1st Edition
    • Volume 86
    • English
    Neuropsychotherapeut... Volume 86, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field, with this updated edition including sections on Pharmacotherapy of psychiatric disorders, Allosteric mechanisms for neuropsychopharmacol... Lipid rafts, Rapid-acting antidepressants, mGlu2/3 receptor antagonists, Nitric oxide: antidepressant mechanisms and inflammation, Anxiety disorders, mGlu receptors and schizophrenia, mAChR ligands for schizophrenia and addiction, PDE10 inhibitors, Obsessive-compulsive disorder, Addiction disorders (including eating), Dopamine D1 PAMs as a New Mode for Treatment of Neuropsychiatric Disorders, and more.

  • Freshwater Microbiology

    Perspectives of Bacterial Dynamics in Lake Ecosystems
    • 1st Edition
    • Suhaib A. Bandh
    • English
    Freshwater Microbiology: Perspectives of Bacterial Dynamics in Lake Ecosystems provides a comprehensive and systematic analysis of microbial ecology in lakes. It offers basic information on how well the bacterial community composition varies along the spatio-temporal and trophic gradients along with the evaluation of the bioindicator species of bacteria so as to act as a key to predict the trophic status of lake ecosystems. The book helps to identify the factors of potential importance in structuring the bacterial communities in lakes as it delves into the dynamics and diversity of bacterial community composition in relation to various water quality parameters. It helps to identify the possibility of bioremediation plans and devising future policy decisions, with better conservation and management practices.

  • Ecophysiology of Pesticides

    Interface between Pesticide Chemistry and Plant Physiology
    • 1st Edition
    • Talat Parween + 1 more
    • English
    Ecophysiology of Pesticides: Interface between Pesticide Chemistry and Plant Physiology is the first comprehensive overview of the physical impact of this increasingly complex environmental challenge. Designed to offer state-of-the-art knowledge, the book covers pesticide usage and its consequences on the ecophysiology of plants. It includes the challenge of policymaking in pesticide consumption and a risk analysis of conventional and modern approaches on standard usage. In addition, it summarizes research reports pertaining to the physio-ecological effects of pesticides, discusses the environmental risks associated with the over-utilization of pesticides, and covers pesticide usage on the micro-flora and rhizosphere. This book is a valuable reference for plant ecologists, plant biochemists and chemists who want to study pesticide consumption and its biochemical and physiological evaluation effects on plants. It will also be of immense help to university and college teachers and students of environmental biotechnology, environmental botany and plant ecophysiology.

  • Classification Techniques for Medical Image Analysis and Computer Aided Diagnosis

    • 1st Edition
    • Nilanjan Dey
    • English
    Classification Techniques for Medical Image Analysis and Computer Aided Diagnosis covers the most current advances on how to apply classification techniques to a wide variety of clinical applications that are appropriate for researchers and biomedical engineers in the areas of machine learning, deep learning, data analysis, data management and computer-aided diagnosis (CAD) systems design. The book covers several complex image classification problems using pattern recognition methods, including Artificial Neural Networks (ANN), Support Vector Machines (SVM), Bayesian Networks (BN) and deep learning. Further, numerous data mining techniques are discussed, as they have proven to be good classifiers for medical images.

  • Cellular and Animal Models in Human Genomics Research

    • 1st Edition
    • English
    Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth.

  • Optochemical Biology

    • 1st Edition
    • Volume 624
    • English
    Optochemical Biology, Volume 624, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters on a variety of topics, including Cell Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code, Optical Control of Tumor Induction in the Zebrafish, Optogenetic Control by Pulsed Illumination, Optimizing the Photocontrol of bZIP Coiled Coils with Azobenzene Crosslinkers: Role of the Crosslinking Site, Site-Directed RNA Editing in Vivo Can Be Triggered by the Light-Driven Assembly of an Artificial Riboprotein, In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light, and much more.

  • Single-Cell Omics

    Volume 2: Technological Advances and Applications
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.

  • Food Safety and Human Health

    • 1st Edition
    • Ram Lakhan Singh + 1 more
    • English
    Despite advances in hygiene, food treatment, and food processing, diseases caused by foodborne pathogens continue to constitute a worldwide public health concern. Ensuring food safety to protect public health remains a significant challenge in both developing and developed nations. Food Safety and Human Health provides a framework to manage food safety risks and assure a safe food system. Political, economic, and ecological changes have led to the re-emergence of many foodborne pathogens. The globalization of food markets, for example, has increased the challenge to manage the microbial risks. This reference will help to identify potential new approaches in the development of new microbiologically safe foods that will aid in preventing food borne illness outbreaks and provides the basic principles of food toxicology, food processing, and food safety. Food Safety and Human Health is an essential resource to help students, researchers, and industry professionals understand and address day-to-day problems regarding food contamination and safety.

  • Metabolism, Structure and Function of Plant Tetrapyrroles: Control Mechanisms of Chlorophyll Biosynthesis and Analysis of Chlorophyll-Binding Proteins

    • 1st Edition
    • Volume 91
    • English
    Metabolism, Structure and Function of Plant Tetrapyrroles, Volume 91, the latest release in the Advances in Botanical Research series is a compilation of the current state-of-the-art on the topic. Chapters in this new release cover Tetrapyrrole Pigments of Photosynthetic Antennae and Reaction Centers of Higher Plants: Biochemistry, Biophysics, Functions, Molecular Mechanism of Antenna Regulation, Applications, Chlorophyll c: Synthesis, Occurrence, Light-Harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Proteins (FCP), Chlorophyll d and f: Synthesis, Occurrence, Light-harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Protein Complexes, Analysis of Chlorophyll, Precursors and Derivatives by New High-Performance Liquid Chromatography and Mass Spectrometry, and much more.

  • Green Food Processing Techniques

    Preservation, Transformation and Extraction
    • 1st Edition
    • Farid Chemat + 1 more
    • English
    Green Food Processing Techniques: Preservation, Transformation and Extraction advances the ethics and practical objectives of "Green Food Processing" by offering a critical mass of research on a series of methodological and technological tools in innovative food processing techniques, along with their role in promoting the sustainable food industry. These techniques (such as microwave, ultrasound, pulse electric field, instant controlled pressure drop, supercritical fluid processing, extrusion…) lie on the frontier of food processing, food chemistry, and food microbiology, and are thus presented with tools to make preservation, transformation and extraction greener. The Food Industry constantly needs to reshape and innovate itself in order to achieve the social, financial and environmental demands of the 21st century. Green Food Processing can respond to these challenges by enhancing shelf life and the nutritional quality of food products, while at the same time reducing energy use and unit operations for processing, eliminating wastes and byproducts, reducing water use in harvesting, washing and processing, and using naturally derived ingredients.

  • Advances in Agronomy

    • 1st Edition
    • Volume 157
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 157, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Sustainable Biofloc Systems for Marine Shrimp

    • 1st Edition
    • Tzachi Matzliach Samocha
    • English
    Sustainable Biofloc Systems for Marine Shrimp describes the biofloc-dominated aquaculture systems developed over 20 years of research at Texas A&M AgriLife Research Mariculture Laboratory for the nursery and grow-out production of the Pacific White Shrimp, Litopenaeus vannamei. The book is useful for all stakeholders, with special attention given to entrepreneurs interested in building a pilot biofloc-dominated system. In addition to the content of its 15 chapters that cover topics on design, operation and economic analysis, the book includes appendices that expand on relevant topics, links to Excel sheets that assist in calculations, and video links that illustrate important operations tasks.

  • The Dissection of Vertebrates

    • 3rd Edition
    • Gerardo De Iuliis + 1 more
    • English
    Detailed and concise dissection directions, updated valuable information and extraordinary illustrations make The Dissection of Vertebrates, 3rd Edition the new ideal manual for students in comparative vertebrate anatomy, as well as a superb reference for vertebrate and functional morphology, vertebrate paleontology, and advanced level vertebrate courses, such as in mammalogy, ornithology, ichthyology, and herpetology. This newly revised edition of the most comprehensive manual available continues to offer today’s more visually oriented student with a manual combining pedagogically effective text with high-quality, accurate and attractive visual references. This new edition features updated and expanded phylogenetic coverage, revisions to the illustrations and text of the lamprey, shark, perch, mudpuppy, frog, cat, pigeon, and reptile skull chapters, and new sections on amphioxus or lancelet (Branchiostoma, Cephalochodata), a sea squirt (Ciona, Urochordata), shark musculature, a gravid shark, shark embryo, cat musculature, and the sheep heart. Using the same systematic approach within a systemic framework as the first two editions, The Dissection of Vertebrates, 3rd Edition covers several animals commonly used in providing an anatomical transition sequence. Nine animals are covered: amphioxus, sea squirt, lamprey, shark, perch, mudpuppy, frog, cat, and pigeon, plus five reptile skulls, two mammal skulls, and the sheep heart.

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