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The Laboratory Rat

  • 3rd Edition - November 10, 2019
  • Latest edition
  • Editors: Mark A. Suckow, F. Claire Hankenson, Ronald P. Wilson, Patricia L. Foley
  • Language: English

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas suc… Read more

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Description

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.

Key features

  • New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included.
  • All chapters were written by scientific and veterinary experts.
  • This book condenses information from many sources on topics related to the care and use of rats in research.
  • It is the premier source of information on the laboratory rat.

Readership

Veterinarians; researchers who use rats in their experiments on aging, drug addiction, cancer, spinal cord injury, cardiovascular disease, Alzheimer’s disease, spontaneous diabetes, arthritis, and so on

Table of contents

Background of the laboratory rat

1. Historical Foundations

2. Taxonomy and Stocks and Strains

3. Translational Potential of Rats in Research

Biology and care

4. Functional Anatomy and Physiology

5. Clinical Pathology of the Rat

6. Reproduction and Breeding

7. Assisted Reproductive Technologies and Genetic Modification in Rats

8. Analysis of Behavior in Laboratory Rats

9. Nutrition

10. Housing and Environment

Clinical care and disease

11. Medical Management and Diagnostic Approaches

12. Bacterial, Mycoplasmal, and Mycotic Infections

13. Viral Disease

14. Parasitic Diseases

15. Neoplastic Disease

16. Metabolic, Traumatic, and Miscellaneous Diseases

17. Anesthesia, Analgesia, and Euthanasia

18. Care of Surgical and Other Fragile Models

Rats as research models

19. General Experimental Techniques

20. Integrating Biology with Rat Genomic Tools

21. Gnotobiotics and the Microbiome

22. Toxicology

23. Embryology and Teratology

24. Rat Immunology

25. Cardiovascular Research

26. Rat Models of Alcohol Use Disorder

27. Rat Models of Obesity, Metabolic Syndrome, and Diabetes

28. The Rate in Neuroscience Research

29. Rat Models of Central Nervous System Injury

30. Use of the Rat as a Model in Regenerative Medicine

31. Rat Models of Infectious Disease

Product details

  • Edition: 3
  • Latest edition
  • Published: November 11, 2019
  • Language: English

About the editors

MS

Mark A. Suckow

Mark A. Suckow is a private consultant in laboratory animal medicine and Professor (Emeritus) in Biomedical Engineering at the University of Kentucky where he previously served as Attending Veterinarian and Associate Vice President for Research. He received his DVM from the University of Wisconsin and subsequently completed a post-doctoral residency in laboratory animal medicine at the University of Michigan. Dr. Suckow has 35 years of experience in laboratory animal medicine, regulatory compliance, and animal facility management. With an interest in the use of animal models for cancer research, vaccinology, and biomaterials development, Dr. Suckow has published greater than 115 papers in refereed journals and has seven issued patents related to vaccine adjuvants and cancer vaccines. He has written or edited over 20 books on topics related to research and laboratory animal medicine. Further, he served as the 2006 President of the American Association for Laboratory Animal Science and the 2011 President of the American Society of Laboratory Animal Practitioners; and he currently serves as an emeritus member of the Council on Accreditation of AAALAC, International and as Editor in Chief for the Journal of the American Association for Laboratory Animal Science.
Affiliations and expertise
Private Consultant

FH

F. Claire Hankenson

F. Claire Hankenson, DVM, MS, is the Director of MSU Campus Animal Resources and Attending Veterinarian at the Michigan State University. Research interests are refinements in the case and use of animals involved in research studies, particularly rodent clinical medicine, tail biopsy evaluations and humane endpoints.
Affiliations and expertise
Director, MSU Campus Animal Resources, Michigan State University, East Lansing, MI, USA

RW

Ronald P. Wilson

Ronald P. Wilson, VMA, MS, DACLAM, is the Professor and Chair of Comparative Medicine at Pennsylvania State University. Research interests are related to experimental surgery, pain, analgesia and anesthesia of laboratory animals.
Affiliations and expertise
Professor and Chair, Department of Comparative Medicine, Penn State University College of Medicine, Hershey, PA, USA

PF

Patricia L. Foley

Patricia L. Foley, DVM, DCLAM, is the Director, Division of Comparative Medicine at Georgetown University.
Affiliations and expertise
Director, Division of Comparative Medicine, Georgetown University, Washington, DC, USA

View book on ScienceDirect

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