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Books in Organic chemistry

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71-80 of 977 results in All results

Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery

  • 1st Edition
  • October 15, 2022
  • Genevieve Dable-Tupas + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 4 4 1 2 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 9 6 2 - 2
Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery. Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists.

Fused Pyrimidine-Based Drug Discovery

  • 1st Edition
  • October 8, 2022
  • Raj Kumar
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 6 1 6 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 6 1 7 - 2
Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers the chemistry and biological activities, as well as the design of novel fused-pyrimidine scaffolds. N-Heterocyclic scaffolds are found in most known drug candidates, and are of interest to medicinal and organic chemists to design, synthesize and evaluate their biological properties. A variety of fused-pyrimidine molecules have been synthesized and extracted from natural resources, and are found to exhibit various biological activities such as antifolates, anticancer agents, analgesics, antimetabolites, CNS active agents and many more. Some of these scaffolds like purines are also known to have involvement in biological processes and are part of the framework of genetic material. This book focuses on the classification, structural chemistry, and chemical and physical properties along with various approaches for their synthesis. This book is ideal for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. 

Studies in Natural Products Chemistry

  • 1st Edition
  • Volume 75
  • September 27, 2022
  • Atta-ur Rahman
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 1 2 5 0 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 2 5 2 - 5
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

Recent Developments in the Synthesis and Applications of Pyridines

  • 1st Edition
  • September 17, 2022
  • Parvesh Singh
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 2 2 1 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 5 9 - 8
Recent Developments in the Synthesis and Applications of Pyridines　is a comprehensive　handbook　for　organic chemists　working on innovative approaches to the synthesis of pyridines.　Written　by scientists in both academia and industry and designed to be a standalone reference, the book　features　reviews, research results and case studies　on　synthetic methods　and　applications　of pyridine-based　chemotypes.　The book will　bridge　the gap between industry and academia by presenting　recent innovative approaches to the synthesis of pyridines,　diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.　 The role of computational chemistry in the development of pyridine-based bioactive molecules　is also included. This reference is essential for researchers　in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.　

N-Sulfonated-N-Heterocycles

  • 1st Edition
  • August 26, 2022
  • Galal H. Elgemeie + 7 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 2 1 7 9 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 2 1 8 2 - 2
N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study.

Contemporary Chemical Approaches for Green and Sustainable Drugs

  • 1st Edition
  • August 26, 2022
  • Marianna Torok
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 2 2 4 8 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 2 7 1 - 2
Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science.

Photochemistry of Heterocycles

  • 1st Edition
  • August 20, 2022
  • Maurizio D’Auria + 4 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 7 4 6 - 5
Photochemistry of Heterocycles is a comprehensive review of the topic, including photooxidation, photoreduction and photoaddition reactions as well as industrial aspects of heterocyclic photochemistry. Many materials used for the manufacturing of OLEDs and other electrooptical switches contain heterocycles, and the use of small molecules or polymers containing heterocyclic substances are being studied as new photovoltaic materials. This reference is ideal for synthetic organic chemists, specifically researchers working in organic photochemistry, as well as medicinal chemists and material scientists. Heterocyclic compounds are widely used in the modern world, and most of the drugs currently in use have heterocyclic nuclei among their constituents. These compounds are subject to a photochemical degradation processes which must be known and prevented.

Applications of Nanotechnology in Drug Discovery and Delivery

  • 1st Edition
  • August 17, 2022
  • Chukwuebuka Egbuna + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 4 4 0 8 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 9 3 1 - 8
Applications of Nanotechnology in Drug Discovery and Delivery, in the Drug Discovery Update series, presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials. This book brings together a global team of experts, making it an essential resource for researchers, drug developers, medicinal chemists, toxicologists and analytical chemists.

Benzodiazepine-Based Drug Discovery

  • 1st Edition
  • August 16, 2022
  • Farzad Zamani + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 4 5 1 6 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 6 0 1 0 - 9
Benzodiazepine-Based Drug Discovery covers benzodiazepines and benzothiazepines, which constitute two pivotal classes of heterocyclic compounds widely used as core structures of medicinal drugs for the treatment of depression, epilepsy, seizures and muscle spasms. 1,4-Benzodiazepine, 1,5-benzodiazepine, and 1,5-benzothiazepine are the most studied groups of benzodiazepines and benzothiazepines because of their outstanding potential biological activities. This book offers a broad range of recent developments and detailed coverage of the synthesis and biological activities of the drugs based on benzodiazepine and benzothiazepine matrixes, and is an ideal reference guide to researchers working in organic and medicinal chemistry. The importance of these privileged pharmacophores is not limited to the treatment of psychotic disorders because minor changes in the structures can generate various biological activities. They represent a wide range of therapeutic functions such as anticonvulsant, antianxiety, anti-depressant, antiviral, anti-HIV, anti-inflammatory, anticoagulant, anti-obesity, endothelin antagonist, cholecystokinin antagonist, and vasopressin receptor antagonist activities.

Comprehensive Aryne Synthetic Chemistry

  • 1st Edition
  • July 20, 2022
  • Hiroto Yoshida
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 1 5 3 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 9 2 4 - 0
Arynes have been important, well-recognized reactive intermediates in organic chemistry since the first speculation of their existence at the beginning of the 20th century. In recent years, synthetic chemistry with arynes has experienced a remarkable revival, leading to diverse new reactions that provide convenient and direct access to various aromatic compounds of high synthetic significance. Comprehensive Aryne Synthetic Chemistry summarizes the progress in the synthetic utilization of arynes for noncatalytic and transition metal-catalyzed reactions developed in the last 20 years. The book covers a broad range of topics including methods of generating arynes, regioselectivity, electrophilic couplings, pericyclic reactions, transition metal-catalyzed reactions, and cycloadditions. It is ideal for advanced students and researchers working in synthetic organic chemistry in academia and industry.

Related subjects

Bioorganic chemistry

Carbohydrate chemistry

Combinatorial chemistry

Heterocyclic chemistry

Medicinal chemistry

Natural products chemistry

Organic synthesis

Pharmaceutical chemistry

Physical organic chemistry

Phytochemistry

Stereochemistry