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Elsevier

Books in Life sciences

  • Innovative Theranostic Strategies Targeting Cancer

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Innovative Theranostic Strategies Targeting Cancer focuses on the latest advances in cancer theranostics, emphasizing clinical and preclinical applications. The volume provides in-depth analyses of various cancer types, covering diagnostics, targeted therapies, and innovative strategies like AI and biomarker-based treatments. It combines fundamental knowledge with practical insights, making it a comprehensive resource for researchers and clinicians involved in oncology research and treatment. The book highlights emerging trends, market developments, and cutting-edge technologies, offering a multidisciplinary perspective to support personalized cancer care.By addressing critical challenges and opportunities in theranostics, it aims to facilitate knowledge exchange and foster new approaches for better patient outcomes. This volume serves as an essential guide for academia seeking to stay current with the rapidly evolving field of cancer theranostics.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment provides a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • Euphorbiaceae Family Oriented Drug Discovery

    Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family
    • 1st Edition
    • Bingjie Li + 1 more
    • English
    Euphorbiaceae Family Oriented Drug Discovery, Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family, a volume in the Drug Discovery Opinions series, aims to comprehensively explore the isolation, identification, synthesis, and drug discovery based on natural products derived from the Euphorbiaceae family. Focused on the isolation, identification, synthesis of bioactive compounds, and drug discovery techniques, the contents of the book are organized into ten chapters. The book opens with an introduction to the Euphorbiaceae family, its botanical overview, medicinal significance, and the importance of exploring its natural products for drug discovery.The next chapters focus on specific techniques for identification and synthesis of natural products, cover the antitumor activities and mechanisms of action of natural products, and discuss the specific antimicrobial properties and mechanisms of action. Final sections discuss anti-inflammatory properties, pharmacology, drug discovery processes for Euphorbiaceae Natural Products, and describe challenges and future directions in research. The final chapter presents final considerations, summarizing key findings and insights from the book.

  • Gold Nanoparticle Therapeutics in Alzheimer's Disease

    Revolutionizing Diagnosis and Treatment
    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    Gold Nanoparticle Therapeutics in Alzheimer's Disease: Revolutionizing Diagnosis and Treatment is an essential resource that delves into the groundbreaking use of nanotechnology in the fight against one of the most challenging neurodegenerative disorders. This volume offers an in-depth exploration on how gold nanoparticles can be used to enhance the diagnosis, treatment, and overall understanding of Alzheimer's disease. By examining the molecular mechanisms that enable nanoparticles to cross the blood-brain barrier, the book highlights their role in inhibiting amyloid fibrils and their potential as precise diagnostic tools.Covering a wide range of topics, this comprehensive guide serves as an invaluable reference for researchers, clinicians, and industry professionals at the forefront of Alzheimer's research and nanomedicine.

  • Antimicrobial Resistance in the 21st Century

    Understanding and Combating the Rising Threat
    • 1st Edition
    • Dipayan Das + 3 more
    • English
    Antimicrobial Resistance in the 21st Century: Understanding and Combating the Rising Threat addresses one of the greatest public health challenges of our time, antibiotic resistance. This book explores the science, history, and global impact of this crisis, providing readers with the knowledge they need to understand the problem and take necessary action. It meticulously unpacks the genetic, biochemical, and evolutionary mechanisms behind antibiotic resistance, while examining how human behaviors—from healthcare practices to agricultural methods—fuel its spread. It highlights the critical roles of environmental factors, misuse of antibiotics, and gaps in diagnosis and stewardship that exacerbate resistance across both clinical and community settings. It also examines innovative solutions, including next-generation antibiotics, alternative therapies, vaccines, and advances in infection control, alongside the global policy strategies necessary to combat this threat. By addressing the scientific, medical, economic, and sociocultural dimensions of antimicrobial resistance, this book provides a roadmap for coordinated, multidisciplinary efforts to preserve antibiotic efficacy and safeguard public health for future generations. It is written by global experts for researchers and scientists in microbiology, infectious diseases, public health, and pharmacology. It is also of interest to healthcare professionals such as clinicians, pharmacists, and nurses, as well as policymakers, public health officials, students, and industry professionals.

  • Artificial Intelligence (AI) in Cancer Biology

    Advancements in Diagnosis and Treatment
    • 1st Edition
    • Sadhna Aggarwal
    • English
    Artificial Intelligence (AI) in cancer biology: Advancements in Diagnosis and Treatment explores the revolutionary impact of AI on cancer biology and oncology. This comprehensive volume delves into AI technologies, including machine learning and deep learning, enhancing our ability to understand, diagnose, and treat cancer with unprecedented precision. The book covers a wide range of topics, from cancer biology fundamentals to AI-driven techniques in diagnosis and personalised treatment. It discusses medical imaging, genomics, drug discovery, and predictive modelling, along with ethical and regulatory considerations, offering a holistic view of AI in cancer research. For academic audiences, this book provides invaluable insights into improving clinical outcomes and patient care. Researchers and clinicians will benefit from the detailed analysis of AI applications, while students and scholars will find a wealth of information to support their studies and future innovations in cancer treatment.

  • Genetic Advances in Inborn Errors of Immunity

    • 1st Edition
    • Volume 117
    • English
    Genetic Advances in Inborn Errors of Immunity, published as Volume 117 of the serial Advances in Genetics, provides a comprehensive and up‑to‑date overview of the rapidly evolving genetic landscape underlying inborn errors of immunity (IEI). Bringing together authoritative contributions from leading experts, this volume examines how advances in genomics, molecular diagnostics, and functional immunology have transformed the understanding, classification, and clinical management of primary immunodeficiency disorders. The chapters span severe monogenic conditions to complex, polygenic phenotypes, highlighting both mechanistic insights and translational implications. Collectively, the volume serves as an essential reference for researchers and clinicians seeking to understand how genetic discoveries are reshaping immunology and precision medicine.

  • Heavy Metals in Food and Food Systems

    Assessment, Risks, Regulations, and Sustainable Mitigation Strategies
    • 1st Edition
    • Matthew Chidozie Ogwu + 1 more
    • English
    Heavy Metals in Food and Food Systems: Assessment, Risks, Regulations, and Sustainable Mitigation Strategies offers a timely, authoritative examination of how toxic metals enter the food chain, the risks they pose, and strategies to reduce exposure. With increasing environmental contamination, understanding pathways from soil, water, and air to food products is essential. This book provides tools for assessing contamination, navigating regulatory standards, and implementing mitigation measures to protect public health and ensure food safety globally. The content is organized into four parts: sources and pathways of heavy metal contamination; transfer during agricultural practices and food processing; detection methods and risk assessment; and governance, mitigation, and future challenges. It covers contamination sources, analytical techniques, exposure risks, and international regulations. Real-world case studies and innovations highlight practical solutions for reducing heavy metal risks across the food system. This book is an essential resource for researchers, faculty, and industry professionals in food science, toxicology, environmental health, and policy. It supports graduate education and helps policymakers develop effective strategies to safeguard food supplies and promote sustainable practices worldwide.

  • Prof. of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 52
    • English
    Physical and chemical data, synthesis or degradation pathways, various analytical techniques for identification and quantification, multiple separation methods, and the pharmacology of drug substances are essential at all stages of pharmaceutical development and are invaluable to practitioners; however, they are scattered throughout the scientific literature. The Analytical Profiles of Drug Substances and Excipients compiles this information into a singular source. No other book series delivers this crucial information as swiftly and relevantly. The Profiles series comprises review articles and database compilations organized into five principal categories: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology for the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. The 52nd volume of Profiles of Drug Substances, Excipients, and Related Methodology offers detailed profiles of five pharmaceutical compounds: Pazopanib, Fenofibrate, Sumatriptan, Beclomethasone dipropionate, and Ceftaroline fosamil. This volume contains a review article on Stimuli-Responsive Polymers, detailing their types, classification, and applications in drug delivery.

  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1st Edition
    • Syed Mudasir Ahmad + 3 more
    • English
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.

  • Gut Health in Diabetes and Gastrointestinal Wellness

    Mechanisms and Clinical Applications
    • 1st Edition
    • Sushil Kumar Dubey + 3 more
    • English
    Gut Health in Diabetes and Gastrointestinal Wellness delves into the intricate relationship between gut microbiota and diabetes, emphasizing their significant impact on gastrointestinal health. This book bridges the gap between cutting-edge research and practical applications, offering a comprehensive exploration on how the gut microbiome affects both metabolic and gastrointestinal health. By examining current scientific findings, the book elucidates the mechanisms through which gut bacteria impact insulin sensitivity, glucose metabolism, and inflammatory responses. Additionally, practical strategies for optimizing gut health are provided, encompassing dietary recommendations, lifestyle modifications, and targeted interventions.The gut microbiome plays a crucial role in metabolic and gastrointestinal functions, and recent research has illuminated the mechanisms by which gut bacteria influence conditions such as diabetes, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Dysbiosis, or the imbalance of gut microorganisms, can disrupt glucose metabolism, lead to insulin insensitivity, and promote chronic inflammation, all of which contribute to the progression and development of metabolic diseases like diabetes. Furthermore, gut dysbiosis is linked to various gastrointestinal disorders, often worsening symptoms and complicating treatment efforts.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Microbiome Stimulants for Crops

    Mechanisms and Applications
    • 2nd Edition
    • James F. White + 1 more
    • English
    Fully revised and updated, Microbiome Stimulants for Crops: Mechanisms and Applications, Second edition continues to provide the latest developments in the real-world development and application of these crop management alternatives in a cost-effective, yield protecting way. Utilizing the plant microbiome as a safe crop management alternative or supplement to chemical fertilizers and other agrochemicals may offer more sustainably produced crops at reduced cost with less environmental degradation. Interest in the approach has led to continuing growth and development of an industry based on applications of microbes in agriculture, with many companies developing products that involve microbes, or biostimulants that affect the plant microbiome. As with the first edition, this book fills the need for comprehensive insights into the potential of this approach, and the new edition includes new chapters as well as updates to existing chapters to ensure that the latest scientific insights are included. It continues to provide a single volume resource designed to address questions of research, development and application.Microbio... Stimulants for Crops supports the field by providing information regarding mechanisms and practical information needed to support the growing microbial inoculant and biostimulant industry, and further to focus scientific research toward areas where more investigation is needed.

  • Proteomics and Metabolomics in Drug Discovery

    • 1st Edition
    • Volume 155
    • English
    Proteomics and Metabolomics in Drug Discovery explores how large-scale protein and metabolite analysis is transforming the identification, validation, and development of new therapeutic targets. The book highlights emerging technologies, analytical strategies, and real-world applications that support biomarker discovery, mechanism-of-action studies, and precision medicine approaches in modern drug development.

  • Nature's Blueprint

    Biomimicry for Sustainable Innovation
    • 1st Edition
    • Fayaz A. Malla + 1 more
    • English
    Nature's Blueprint: Biomimicry for Sustainable Innovation explores how nature’s time-tested patterns, processes, and designs can inspire innovative solutions to today’s pressing environmental and technological challenges. This book examines the field of biomimicry and highlights the need for sustainable development and eco-friendly innovations that are aligned with ecological principles. The book is organized into three parts. The first part introduces core concepts such as learning from nature’s genius, principles and patterns of life, and the ethical dimensions of biomimicry. The second part examines structural ingenuity, energy efficiency, circular systems, water management, and biomimetic materials through detailed case studies. Finally, the third part explores resilience, sustainable agriculture, transportation, urban design, and methods for measuring success. Nature's Blueprint: Biomimicry for Sustainable Innovation is for readers seeking nature-inspired solutions to ecological challenges. It’s an essential resource for advancing sustainable development worldwide.

  • Nutritional Epigenetics

    Food-Derived microRNAs in Health and Disease
    • 1st Edition
    • Shariful Islam + 3 more
    • English
    Nutritional Epigenetics: Food-Derived microRNAs in Health and Disease offers perspective on the role of dietary microRNAs as pivotal epigenetic regulators influencing health trajectories and disease susceptibility. The book brings together current research on the bioavailability and molecular mechanisms by which plant and food-derived microRNAs modulate gene expression, including their crosstalk with DNA methylation, histone modifications, and gut microbiota. Detailed food-specific chapters examine the epigenetic impact of key dietary sources such as Brassicaceae (crucifers), rice, milk, and fermented products, highlighting their transgenerational and life-stage effects. Practical insights into food processing, culinary traditions, and the design of microRNA-fortified products bridge the gap between bench science and real-world applications. Nutritional Epigenetics equips researchers, clinicians, and industry innovators with a resource that advances the understanding of microRNA-mediated nutritional epigenomics, while guiding the development and safety assessment of microRNA-enhanced functional foods. By integrating molecular biology with population-level evidence and translational strategies, this text fosters the development of novel dietary interventions aimed at optimizing health across the lifespan and mitigating chronic disease risk.

  • Anthocyanins in Food

    Chemistry, Health Benefits and Food Applications
    • 1st Edition
    • Bai Weibin
    • English
    Anthocyanins in Food: Chemistry, Health Benefits and Food Applications provides a detailed exploration of anthocyanins - a class of natural pigments with significant health benefits and wide-ranging applications in the food industry. It offers a comprehensive overview of anthocyanins: from their chemical structure and biosynthetic pathways to their role in promoting health and their use as natural food colorants. It covers the latest research findings, practical applications, and innovative technologies related to anthocyanins, making it an essential resource for researchers, industry professionals, and students in food science and nutrition.

  • Neurochemical Substrates of Addiction Medicine

    • 1st Edition
    • Mohammad Banazadeh + 2 more
    • English
    Neurochemical Substrates of Addiction Medicine offers an in-depth exploration of the complex interplay between neurochemistry and addiction, providing critical insights for researchers, clinicians, and students alike. This book is structured into four comprehensive sections, beginning with an examination of the distribution of neurotransmitters across key brain circuitry involved in addiction, such as the mesolimbic, striatal, frontal, insular, and thalamic systems. Each chapter meticulously describes how these circuits contribute to addictive behaviors and the underlying neurobiological mechanisms. The second section delves into the major neurotransmitter systems—including dopaminergic, glutamatergic, GABAergic, adrenergic, serotonergic, cholinergic, endogenous opioid, and purinergic systems—highlighting their roles in addiction.Following this, the book addresses the neuropharmacology of various drugs of abuse, including nicotine, opioids, alcohol, psychomotor stimulants, cannabinoids, psychedelics, sedative-hypnotics, caffeine, and antihistamines, detailing how these substances alter neurochemical pathways. The final section expands the discussion to behavioral addictions, exploring the neurochemical substrates associated with disorders such as pathological gambling, internet use, sexual addiction, and binge eating.

  • Value-Based Healthcare in the Digital Age

    Economic Efficiency and Transformation
    • 1st Edition
    • Miltiadis Lytras + 2 more
    • English
    Value-Based Healthcare in the Digital Age: Economic Efficiency and Transformation addresses the transformation in global healthcare that has been driven by digital innovation, economic efficiency, and value-based care. The book provides comprehensive frameworks that integrate health economics, digital transformation, and patient-centered value delivery. Facing rising costs, aging populations, and chronic diseases, the healthcare sector also sees opportunities in AI, machine learning, blockchain, and IoT for smarter, more efficient delivery. Users will find an exploration of the economic implications of these technologies, offering strategies to align them with value-based care principles, optimize resources, and improve patient outcomes.For academics, policymakers, and healthcare professionals, this book bridges theory and practice with cutting-edge research and real-world case studies. It equips readers with the knowledge and frameworks to navigate the evolving healthcare landscape, emphasizing global perspectives and diverse technological applications, ultimately driving innovation and economic sustainability in healthcare delivery.

  • Complications in Neuroanesthesia

    • 2nd Edition
    • Hemanshu Prabhakar
    • English
    Complications in Neuroanesthesia, Second Edition offers an extensive examination of the complications associated with neuroanesthesia practice, emphasizing both new and existing challenges in the field. This updated edition introduces critical topics such as locked-in syndrome, cerebellar mutism syndrome, delirium, awareness, memory loss, perioperative stroke, and coma, alongside established complications like brain herniation, hydrocephalus, and seizures. Each complication is meticulously examined in separate chapters, detailing the pathophysiology, mechanisms, diagnosis, treatment, and prevention strategies. This book also addresses cardiovascular issues, including stunned myocardium, as well as fluid and electrolyte disturbances like glucose dysregulation and conditions like post-dural puncture headache, malignant hyperthermia and reperfusion injury. Written in an accessible format for quick navigation, this resource provides invaluable insights into the perioperative management of neurosurgical and neurologic patients. This book is a practical tool for trainees, clinicians, and researchers in anesthesia, neuroanesthesia, neurosurgery, neurocritical care, and neurology. By highlighting preventable mishaps, this edition aims to enhance the safety and efficacy of neuroanesthesia and neurocritical care practice.

  • Medicinal and Aromatic Plants in the Post-Genomics Era

    • 1st Edition
    • Rhydum Sharma + 2 more
    • English
    Medicinal and Aromatic Plants in the Post-Genomics Era brings together current research on species long valued for their therapeutic and industrial properties, now drawing renewed interest from the pharmaceutical, nutraceutical, cosmetic, and agricultural sectors amid rising demand for natural alternatives to synthetic chemistry.At the core of this shift is a deeper molecular understanding of how these plants produce their bioactive constituents. Genomics, transcriptomics, proteomics, and metabolomics have exposed the genetic architecture and biochemical pathways behind secondary metabolite synthesis, while computational biology helps make sense of the resulting complexity. Together, these tools are speeding up compound discovery and clarifying how such molecules function biologically.The chapters that follow turn this knowledge into practice: systems biology and metabolic engineering for boosting yields, CRISPR-based genome editing for reprogramming pathways, synthetic biology and AI-driven modeling for predicting and designing new biosynthetic routes, and emerging production platforms — from hairy root cultures to inducible expression systems — for expanding output sustainably.Taken together, the volume traces a progressive arc: from reading a plant's genetic blueprint to realizing its potential as a source of usable, real-world solutions in the clinic, the field, and the marketplace, offering a practical reference for both researchers and industry practitioners working at the intersection of plant biology and biotechnology.

  • The Neurobiological Underpinnings of Addiction Medicine

    Focusing on Novel Approaches
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    The Neurobiological Underpinnings of Addiction Medicine: Focusing on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD.This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike.

  • Responsible AI in Healthcare

    Navigating the EU AI Act and Global Regulatory Frameworks
    • 1st Edition
    • Miltiadis Lytras + 3 more
    • English
    Responsible AI in Healthcare: Navigating the EU AI Act and Global Regulatory Frameworks examines how health systems design, deploy, and oversee AI under evolving legal and ethical mandates. It provides an integrated, practice‑oriented roadmap for compliance and responsible innovation. This book offers the first integrated, comparative treatment of the EU AI Act and global regulatory frameworks for healthcare, translating ethics and law into operational evaluation, governance, and value assessment. Through structured cases, decision tools, and stakeholder methods, it equips researchers and clinicians to design, validate, and deploy AI responsibly—and to keep learning as regulations evolve. Readers gain actionable tools, checklists, and frameworks to operationalize ethical AI, prepare for audits and certifications, and anticipate global convergence (“Brussels Effect”) shaping digital health. The volume serves clinicians, administrators, developers, policy and legal experts seeking rigorous yet accessible guidance.

  • Nanomedicine for Neurological Disorders

    Design, Delivery, and Clinical Perspectives
    • 1st Edition
    • Saman Fatima + 4 more
    • English
    Nanomedicine for Neurological Disorders: Design, Delivery, and Clinical Perspectives addresses the urgent need for innovative solutions in treating complex neurological and neurodegenerative diseases. As the global burden of conditions such as Alzheimer's, Parkinson's, multiple sclerosis, and brain tumors continues to rise, the scientific community faces the critical challenge of safely and effectively delivering therapeutics across the blood-brain barrier. This reference meets the needs of neuroscientists, clinicians, pharmaceutical scientists, and biomedical engineers seeking advanced strategies and translational insights in neuro-nanomedicine. The contents are structured to provide a comprehensive, interdisciplinary exploration of the field. Chapters cover the anatomy and connectivity of the human brain, the global burden and mechanisms of neurological disorders, conventional and nanomedicine-based drug delivery systems, and the intricacies of the blood-brain barrier. Readers will benefit from detailed analyses of nanocarrier engineering, stability, analytical techniques, toxicological safety, regulatory challenges, and artificial intelligence-driven drug design. Real-world case studies, clinical trial data, and future outlooks are presented alongside ethical and patient-centric considerations, ensuring a holistic perspective on the evolving landscape of neuro-nanomedicine. Nanomedicine for Neurological Disorders delivers essential benefits by bridging the gap between laboratory innovation and clinical practice. It equips readers with practical knowledge, foundational advances, and visionary insights to inspire new research directions, inform better decision-making, and accelerate the development of safer, more precise treatments for brain-related disorders. This reference is an indispensable resource for researchers, clinicians, and innovators at the forefront of neurological therapeutics.

  • Oilseeds and Fats

    Trait Improvement, Processing, Properties and Applications
    • 1st Edition
    • Sanju Bala Dhull + 2 more
    • English
    Oilseeds and Fats: Trait Improvement, Processing, Properties and Applications covers recent developments in the areas of oilseeds production practices, breeding, and genetic improvement for sustainable production, with an emphasis on processing technologies and nutrition. The book explores eco-friendly extraction methods, waste reduction techniques, and the potential of using waste by-products for energy production or other applications. Specific sections deal with production, breeding, processing methods, composition, and consumption trends, and then delve into oilseeds and fats origin, composition, and characteristics, as well as the principles and methods involved in processing and refining these resources.Additional sections cover oilseed crops processing, properties, and application, offering insights into the utilization of oilseeds and fats to develop new products that meet consumers' evolving preferences, thus addressing environmental concerns. With increasing awareness of environmental issues and climate change, the book underscores the significance of sustainable practices in the oilseed and fats industry.

  • Methods in Systems Bioinorganic Chemistry

    • 1st Edition
    • Volume 741
    • English
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Arginase: Structure, Function, and Therapeutic Targeting

    • 1st Edition
    • Volume 740
    • English
    Arginase: Structure, Function, and Therapeutic Targeting, Volume 740 in the Methods in Enzymology series, provides a comprehensive, methodology-driven perspective on arginase research spanning molecular, biochemical, and translational domains. Chapters in this new release include Expression, Purification, and Structural Characterization of Human and Leishmania Arginase with Comparative Analysis of Structures from the Protein Data Bank, Synthesis of First-Generation Arginase Inhibitors, Computational and Structure-Guided Design of Arginase Inhibitors, Metal Substitution in Arginase: Experimental Approaches to Study Metal-Dependent Catalysis, Therapeutic Arginase Formulations: PEGylation, Stability, and Advanced Delivery Systems, and much more.Additional chapters cover Dual ARG1/ARG2 Inhibition: Experimental and Structural Strategies for Inhibitor Design and Optimization, Synthesis of Second-Generation Arginase Inhibitors, Cryo-EM Workflow and Structural Characterization of Arginase–Antibody Complexes, Development and Validation of an Electrochemical Assay for Arginase Activity, Experimental and Structural Analysis of H. pylori Arginase in Gastric Immune Evasion, Agmatinase and Alternative Arginine Utilization Pathways in Bacteria: Biochemical and Functional Perspectives, Catalytic Diversification of the Arginase Fold: Structural and Mechanistic Insights from DcsB, Beyond Arginase: Structural Biology of the Extended Guanidinase Family, Plant Arginase: Structural and Functional Roles in Nitrogen Metabolism, and much more.

  • Thiamine Pyrophosphate (TPP)-Dependent Enzymes

    • 1st Edition
    • Volume 736
    • English
    Thiamine Pyrophosphate (TPP)-Dependent Enzymes, Volume 736 in the Methods in Enzymology series covers this diverse group of ubiquitous enzymes with timely chapters on Methods for Studying ThDP-dependent Mycobacterial MenDs (SEPHCHC Synthases), Mammalian 2-hydroxyacyl-CoA lyases, discovery and assays, Anti-infective target 1-deoxy-d-xylulose-5... synthase (DXS) and drug design for enzyme inhibition, Expression, Purification, and Mechanistic Studies of DXP synthases from Deinococcus radiodurans, Plasmodium falciparum, and Plasmodium vivax, Comparison of the catalysis of ThPP-dependent enzymes AHAS, ALS, and DXS, and much more.Additional sections cover Plant and fungal acetohydroxyacid synthases (AHAS): Methods for heterologous expression, kinetic characterization, and structural analysis, Biochemical and Structural characterization of novel ‘split-gene’ archeal transketolases, 4-Hydroxybenzoylform... decarboxylase enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5: characterization and involvement in bacterial lignin degradation, Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration, Repurposing TPP-dependent enzymes with anodic oxidation for the conversion of aldehydes to enantioenriched carboxylic acids, and much more.

  • Biology

    A Human Health Perspective
    • 1st Edition
    • Harry E. Peery + 2 more
    • English
    Biology: A Human Health Perspective offers important medical case histories and complex color illustrations, interacts with the reader, and asks questions throughout. Sections cover the basic chemistry of biology and cell origins, and energy and protein processing before discussing cell reproduction, genetics, evolution, and their place in public healthcare. Clinical applications and medical terminology are also included across chapters, and pioneering medical developments such as holographic surgery, robotic neurosurgery, and tractography are featured.This textbook, along with supporting ancillary materials such as PowerPoint slides, solution manuals and quiz banks is a vital resource for all undergraduate students studying biology or for those looking to develop a career in a health profession who need a basic understanding of the field.

  • Principles of Antiviral Drug Development

    Rapid Discovery Technologies and Practical Applications
    • 1st Edition
    • Ailin Liu
    • English
    Principles of Antiviral Drug Development: Rapid Discovery Technologies and Practical Applications systematically integrates the major experimental techniques and virtual drug screening methods involved in the discovery of antiviral drugs, and provides a detailed discussion of their applications: among them, the combination of virtual drug screening technologies coupled with experimental methods offers strong potential for the rapid discovery of antiviral agents. The book also discusses activity-guided extraction, isolation, and activity evaluation of active components in order to reveal the material basis of antiviral activity and preliminary mechanisms of action. The book also discusses: drug repurposing of approved medicines; and an analysis of the discovery and mechanistic studies of a series of antiviral natural products which offer important information on the needs of future research, development, together with the clinical application of new antiviral drugs.

  • Dry Eye Disease

    A Clinical Handbook
    • 1st Edition
    • James Stuart William Wolffsohn + 2 more
    • English
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Personalized Cancer Medicine through Multiomics

    • 1st Edition
    • Mohammad Azhar Aziz + 1 more
    • English
    Personalized Cancer Medicine through Multiomics explores the integration of multiomics to transform cancer diagnosis and treatment. The book delves into how the convergence of genomics, transcriptomics, proteomics, and metabolomics offers a comprehensive understanding of cancer biology, surpassing traditional single-omics approaches. Sections detail advancements in high-throughput technologies and computational methods, including machine learning, that enable the analysis of complex cancer datasets. Additional content discusses how multiomics identifies unique molecular signatures, novel therapeutic targets, and biomarkers, facilitating precise and individualized treatment strategies, particularly for a heterogeneous cancers.For academics, this book serves as an essential resource, compiling fragmented research into a single, coherent volume. It provides foundational knowledge, the latest advancements, and practical applications of multiomics in personalized medicine. Researchers will benefit from interdisciplinary approaches, real-world examples, and cutting-edge methodologies, making it an invaluable reference for advancing their work in oncology.

  • Green Polymeric Materials in Drug Delivery

    Sustainable Solutions for Therapeutic Applications
    • 1st Edition
    • Parteek Prasher + 5 more
    • English
    Green Polymeric Materials in Drug Delivery: Sustainable Solutions for Therapeutic Applications addresses the critical intersection of polymer science, pharmaceutical technology, and environmental sustainability. This reference responds to the urgent need for eco-friendly drug delivery systems that improve therapeutic outcomes while minimizing ecological impact. It offers researchers and professionals a detailed exploration of green polymers derived from renewable sources and their transformative potential in healthcare. The comprehensive contents cover fundamental principles, synthesis, biocompatibility, formulation strategies, and innovative applications including nanomaterials, hydrogels, vesicular systems, and vaccine delivery. Chapters authored by leading experts examine targeted delivery routes such as mucosal, ocular, transdermal, and neural pathways. Regulatory frameworks and clinical trial insights further support translation from research to practice. Emerging technologies like AI-assisted formulation and 3D printing of implants are also discussed. This reference benefits polymer chemists, pharmaceutical scientists, regulatory experts, and clinicians by providing authoritative knowledge on sustainable materials for drug delivery. It equips readers with the scientific foundation and practical case studies necessary to advance green polymeric technologies in therapeutic development, fostering a sustainable future in pharmaceutical innovation and patient care.

  • Animal Models of Disease Part F

    • 1st Edition
    • Volume 212
    • English
    Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • The Metabolon

    • 1st Edition
    • Volume 739
    • English
    Methods in Enzymology series: The Metabolon, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Cell Death Part F

    • 1st Edition
    • Volume 211
    • English
    Cell Death: Part F, Volume 211 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores Methods to Assess BAX Conformation, Activation, Translocation, and Mitochondrial Outer Membrane Permeabilization, Proximity biotin labelling identification of Bcl-2 protein interactions in live cells, Bimolecular fluorescence complementation assays for investigating Bcl-2 family protein interactions, Assessing apoptotic sensitivity in primary mouse B cells by BH3 profiling, Liposome permeabilization assays to monitor pore formation by cell death proteins, Flow Cytometry Assessment of Mitochondrial Membrane Potential, Biomass, and ROS in OXPHOS-Dependent and Glycolytic Cancer Cells during Cell Death Induction, and much more.Additional chapters cover Assessment of Viability Versus Cell Death: What is What?, Flow cytometry-based drug response profiling of primary B-precursor ALL cells in co-culture with bone marrow-derived stromal cells, An in vitro model of efferocytosis in macrophage foam cells to probe lipid-driven dysregulation of dead cell clearance, Measuring tumor cell killing using in vivo bioluminescence imaging, and more.

  • Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology

    • 1st Edition
    • Swagat Kumar Das + 2 more
    • English
    Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology delves into historical perspectives, current trends, and future projections for research and development of immunological and biopharmaceutical products. Sections explore immunostimulants, natural and synthetic immunostimulants in aquaculture and animal husbandry, immunomodulators, immune boosters, pre- and probiotics in health promotion, cutting-edge immunological techniques for disease diagnosis, immunotherapy in cancer treatment, and transplantation immunology. Following chapters explore the impact on pharmaceutical biotechnology, with discussions on traditional and modern approaches in drug delivery, in silico drug delivery modeling, biocomposites and their pharmaceutical applications, recent advances in monoclonal antibodies production, vaccine development, and much more. Finally, the book covers the pivotal role of AI, machine learning, and data analytics in the clinical study of immunotherapy and pharmaceutical drugs, thus paving the way for enhanced research and development efficiency. Researchers in industry and academia alike will gain valuable insights into the novel principles behind designing and developing immunological and drug products, making this title an essential resource.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 137
    • English
    Advances in Applied Microbiology presents the latest developments and innovative research in applied microbiology, covering topics such as microbial biotechnology, environmental applications, industrial processes, and medical advancements. It offers valuable insights into the practical uses of microorganisms in solving real-world challenges, making it an essential resource for researchers, professionals, and students in microbiology and related fields.

  • Perianal Crohn’s Disease

    Diagnosis and Treatment
    • 1st Edition
    • Bolin Yang + 2 more
    • English
    Perianal Crohn’s Disease: Diagnosis and Treatment includes the latest knowledge, concepts, first-hand theoretical views, and clinical experience of clinical frontline experts in the field of inflammatory bowel disease. The book systematically describes disease phenotypes, clinical features, examination methods, diagnoses, and treatments. It takes a scientific, practical, and systematic account of both common and rare conditions associated with Perianal Crohn’s Disease, offering informative content, clinical case information, cutting-edge viewpoints, and current, authoritative research findings. The book contains a depth of current clinical experience, including the use of photographs to support examples of conditions, methods, and techniques. In addition, it provides clear ideas and a wealth of clinical information for the clinical diagnosis and management of perianal Crohn's disease.

  • Insect Pathology

    • 3rd Edition
    • Nemat Keyhani + 2 more
    • English
    Insect Pathology, Third Edition offers the most comprehensive research on the topic of insect pathology, spanning the diversity of insects with a more diverse array of microbes. This book provides a full update on new approaches for studying the genetics, development, evolution, and ecology of insect pathogens. Written by leading researchers and experts, the book includes coverage of revolutionary genome editing tools, such as CRISPR-Cas9, which have been developed for multiple insect pathogen systems and provides insights into the molecular underpinnings of insect pathogens and their hosts. This book also updates modern molecular techniques, “omics” approaches, and newly applied findings. These new and revised topics are critical for understanding current perspectives in the field, making this book a needed reference for insect pathologists, entomologists, microbiologists, mycologists, nematologists, protistologists, ecologists, and practitioners of biological control of insect pests. New and long-time students of insect pathology will also find this new edition useful.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part A

    • 1st Edition
    • Volume 191
    • English
    Blood-Based Biomarkers for Alzheimer’s and Parkinson’s Disease, Volume 191 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on the development and application of circulating biomarkers in neurodegenerative disorders. It brings together contributions from an international panel, highlighting emerging strategies for early detection, diagnosis, and monitoring of Alzheimer’s and Parkinson’s diseases. Chapters explore a wide range of topics, including the Diagnostic Potential of Exosomes in Neurodegenerative Diseases and Cancer, Blood Biomarkers of Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases, GFAP and the Genetic Code of Astrocyte Activation in Alzheimer’s Disease, and much more.Additional chapters cover Blood-Based Emerging Biomarkers in Early Detection and Diagnosis of Alzheimer’s Disease, Advances in Nanomaterial-Based Biomarker Detection for Neurodegenerative Diseases, Blood-Based Biomarkers in Alzheimer’s and Parkinson’s Disease: From Molecular Pathology to Therapeutic Potential, Blood-Based Biomarkers and Their Role in AD/PD Diagnosis, The Emerging Landscape of Circulatory Biomarkers in Alzheimer’s Disease, Biofluid-Based Biosensors, Biomarkers of Vascular Dementia and Alzheimer’s Disease, Silent Clues in Blood: Proteomic Approach for Alzheimer’s Disease, and more.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 48
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 48, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird’s Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more.Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much more.

  • Lightweight, Real-time Deep Learning Models for Healthcare Applications

    • 1st Edition
    • Tina Babu + 2 more
    • English
    Lightweight, Real-time Deep Learning Models for Healthcare Applications addresses the pressing need for deploying efficient artificial intelligence models in clinical environments constrained by limited computational resources. As AI adoption accelerates in healthcare, this reference targets the gap between advanced deep learning research and practical real-time applications, emphasizing model optimization, privacy, and regulatory compliance. The content comprehensively covers model compression techniques such as pruning, quantization, knowledge distillation, and neural architecture search, alongside federated learning frameworks and real-time inference optimization. Detailed chapters present hardware-aware strategies, security considerations, continuous learning, and regulatory validation. The book also provides extensive case studies and implementation blueprints demonstrating practical deployment on devices like Raspberry Pi, NVIDIA Jetson, and mobile health platforms. This book benefits researchers, clinicians, and healthcare technology professionals by offering practical solutions to develop, validate, and implement AI models that maintain diagnostic accuracy while meeting clinical constraints. It equips students and educators with theoretical foundations and hands-on examples to foster innovation in biomedical AI, ultimately enhancing diagnostic capabilities and patient care in diverse healthcare settings.

  • Technology-Assisted Physical Gait Rehabilitation

    How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy
    • 1st Edition
    • Tomislav Baček + 3 more
    • English
    Technology-Assisted Physical Gait Rehabilitation: How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy explores computational modeling techniques, robotic assistance, data science, and other technological tools and how they can be jointly used in driving and guiding physical gait therapy in impairments such as stroke, traumatic brain injury, and incomplete spinal cord injury. This book gathers experts in robotics, human biomechanics, physical therapy, neuroscience, engineering, and medicine, presenting their ongoing work and discussing their views on the future direction of technology-assisted gait therapy. It showcases the latest advancements in the interdisciplinary and multidisciplinary field of technology-assisted gait therapy and strives to outline the developments in the coming years that are needed/likely to make the next big breakthrough in the field.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 44
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 43 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Content in this new release covers Engineered probiotics for producing phosphoinositol-sn-l... as biosurfactant modulators: Their hydropathy, in potentiating surface tension and scaffold properties into model emulsions.

  • Model Validation and Uncertainty Quantification in Biomechanics

    Sources and Methods of Uncertainty and Variability Analysis - Volume 2
    • 1st Edition
    • Gerhard A. Holzapfel + 2 more
    • English
    Model Validation and Uncertainty Quantification in Biomechanics: Sources and Methods of Uncertainty and Variability Analysis addresses the increasing need to incorporate uncertainty and variability into computational biomechanics. As biomechanical modeling becomes more central to clinical decision-making, deterministic approaches are no longer sufficient to describe biological complexity. This reference provides a systematic treatment of uncertainty quantification, enabling more reliable, patient-specific models in cardiovascular and soft tissue applications. The volume is structured into four main sections. It begins with probabilistic fundamentals and sensitivity analysis, establishing core principles for uncertainty-aware modeling. It then explores sources of uncertainty, including vascular modeling, imaging reconstruction, MRI, ultrasound elastography, and biological variability such as sex differences. The third section focuses on computational methods such as multi-fidelity modeling and Bayesian parameter identification. The final section presents practical applications in vascular systems, cardiac mechanics, and diagnostic techniques, emphasizing clinically relevant case studies.Model Validation and Uncertainty Quantification in Biomechanics: Sources and Methods of Uncertainty and Variability Analysis provides researchers and engineers with rigorous tools to assess model reliability and variability. By combining foundational theory with applied methodologies, it supports the development of robust, predictive biomechanical simulations, advancing translational research and precision medicine in healthcare engineering.

  • Organic Semiconducting Systems for Applications in Biomedical Engineering

    • 1st Edition
    • Neha Rani Kumar + 1 more
    • English
    Organic Semiconducting Systems for Applications in Biomedical Engineering explores the properties and applications of organic semiconductors, which are conjugated systems made from small organic molecules or polymers that exhibit semiconductor characteristics. These materials offer flexibility, lightweight construction, low cost, and large-area production capabilities. Their tunable electronic and optical properties, along with biocompatibility, such as biosensors, smart drug delivery systems, medical diagnostics, and implantable devices.The book targets professionals and students in the fields of organic electronics, biomedical engineering, biomaterials, and environmental science. It provides a comprehensive understanding of organic conjugated systems and their principles, aiding readers in designing innovative solutions for challenges in medical sectors. Additionally, it delves into the latest research findings and practical applications of organic semiconductors, helping readers stay informed and identify new research opportunities. This book clarifies complex concepts, making it suitable for beginners. It also offers a forward-looking perspective on the potential of organic semiconductors to revolutionize biotechnology, inspiring readers to pursue research and innovation for sustainable development.Overall, this book serves as an essential resource for understanding organic semiconductors in biotechnology, biomedical engineering, and bioelectronic applications.

  • Neurogynecology and Associated Neurological Disorders

    • 1st Edition
    • Vishal K. Chavda + 2 more
    • English
    Neurogynecology and Associated Neurological Disorders addresses the emerging interdisciplinary field linking neurology and gynecology, focusing on how neurological disorders impact female reproductive health throughout the lifespan. The book covers foundational neuroanatomy, hormonal influences on neurological function, and specific disorders including headaches, epilepsy, pelvic neuropathies, and mental health conditions related to reproductive stages. It includes clinical guidelines, case studies, diagnostic tools, and treatment protocols tailored to hormonal phases and life stages. The integration of neurobiological mechanisms with gynecological considerations offers readers a robust framework for interdisciplinary collaboration.Reader... will find this to be a great reference that responds to the growing clinical need for integrated understanding and management of conditions such as menstrual migraines, pregnancy-related neuropathies, and menopausal neurological changes.

  • Understanding Molecular Processes using Electrochemical Methods

    • 1st Edition
    • Ashis Kumar Satpati + 1 more
    • English
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

  • Structural Biology of Ubiquitination

    From Mechanisms to Interventions
    • 1st Edition
    • Navaneet Chaturvedi + 1 more
    • English
    Structural Biology of Ubiquitination: From Mechanisms to Interventions provides an in-depth exploration of the structural and biophysical principles governing ubiquitination and their implications in diseases such as cancer and neurodegeneration. The book seamlessly integrates experimental insights with advanced computational methods, including AI-driven drug discovery, molecular modeling, and biophysical simulations, offering a comprehensive toolkit for researchers and clinicians. By bridging fundamental science with translational applications, the book empowers readers to design targeted therapeutics, understand disease mechanisms at the molecular level, and accelerate progress toward personalized medicine.

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