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Elsevier

Books in Life sciences

  • The Plant Seed

    Development, Preservation, and Germination
    • 1st Edition
    • Irwin Rubenstein + 2 more
    • English
    The Plant Seed: Development, Preservation, and Germination presents papers delivered on the symposium on plant seed, held at the University of Minnesota in 1978. The volume discusses the development, preservation, and germination of the plant seed. The topics of this compendium focus on various aspects of the plant seed. The first group of papers describes genetic, hormonal, and molecular events associated with seed development, with particular attention given to the molecular biology of storage protein formation; the second group of papers examines the physiological and genetic aspects of germplasm preservation. The final group of papers examines the molecular aspects of seed germination. The book will be of interest to botanists, biologists, plant breeders, plant physiologists, plant pathologists, and geneticists.

  • Marine Mycology

    The Higher Fungi
    • 1st Edition
    • Jan Kohlmeyer + 1 more
    • English
    Marine Mycology: The Higher Fungi deals with the higher marine fungi, i.e., Ascomycotina, Basidiomycotina, and Deuteromycotina. This book combines features of a monograph with those of a text. It includes sections on ecological groups of fungi and other topics, such as phylogeny, ontogeny, physiology, and vertical and geographical distribution, providing information on known facts and open questions. The taxonomic-descriptiv... part contains complete descriptions of each genus and species, together with substrates, range, etymology of generic and specific names, and literature. There are keys for all species within a given genus, and a general illustrated key leads to the individual species. The taxonomic section is based on examinations of almost all of the filamentous marine fungi, and unpublished data on new hosts and geographical distributions are included for many species. The filamentous higher marine fungi are represented by 149 Ascomycetes, 4 Basidiomycetes, and 56 Deuteromycetes. The majority, namely 191 (91%) of the filamentous fungi, are obligately marine species, whereas the remainder are facultatively marine. One new species and seven new combinations are proposed. The yeasts are treated in a separate chapter and comprise 177 species or varieties.

  • Intensive Care for Neurological Trauma and Disease

    • 1st Edition
    • Barth A. Green + 2 more
    • English
    Intensive Care for Neurological Trauma and Disease presents the progress in intensive care in terms of technological development on life-support and monitoring systems. This book discusses the ideal neurologic intensive care environment that is based on developments in other specialized care units. Organized into 24 chapters, this book begins with an overview of the problem of neurological trauma. This text then presents the accident scene management protocol for acute spinal cord injury as a standard to other forms of trauma system pre-hospital care. Other chapters consider the appropriate drugs and dosages for the management of status epilepticus in the newborn and older children. This book discusses as well the findings on the neurological examination and provides a framework for an etiological classification that has direct therapeutic implications. The final chapter deals with the clinical aspects, diagnosis, and management of neuromuscular diseases. This book is a valuable resource for clinicians and intensive care unit nurses.

  • Lesions and Transplantation

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 7: Lesions and Transplantation describes the chemical and nonchemical production of lesions and preparation and development of transplants, implants, and grafts. This book consists of four sections—chemical and nonchemical lesioning; model systems utilizing lesioning; transplants, implants, and grafts; and assessment of lesions and transplants. In these sections, this volume discusses the excitotoxins as tools for producing brain lesions; use of acromelic acid for production of rat spinal lesions; and opioid and nonopioid antinociception as revealed by lesion studies. The endothelin-1-induced lesions in the brain as a new model of focal ischemia; fetal implants in the lesioned spinal cord of the rat; and hippocampal transplants in oculo are also elaborated. This book likewise covers the assessment of neurochemical function of brain transplants and in vitro electrophysiological analysis of in oculo. This publication is intended for neuroscientists, but is also beneficial to researchers conducting work on lesions and transplants.

  • Blood Platelets in Man and Animals

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • Bernard Maupin
    • G. A. Kerkut
    • English

  • Sterilisation and Disinfection

    Pharmaceutical Monographs
    • 1st Edition
    • T. D. Whittet + 2 more
    • J. B. Stenlake
    • English
    Pharmaceutical Monographs, Volume 3: Sterilisation and Disinfection provides a strong foundation for the proper use of disinfectants in practice. This monograph surveys the types of preparations required to be produced in a sterile condition and explains in detail the methods available for sterilization. This monograph is comprised of four parts. Part 1 discusses the purposes of sterilizing pharmaceutical preparations to prevent the infection of body tissues, fluids, or cavities with organisms that may produce damage or disease. Part 2 provides information concerning the extent of contamination of pharmaceutical materials, which is obtained by means of sterility tests. Part 3 focuses on autoclave design and an explanation is offered of the background against which sterilizers have been developed and the method in which their major components operate. Part 4 describes the various types of disinfectants, including halogens, phenols, alcohols, aldehydes, dyes, furan derivatives, amidines, surface-active compounds, and derivatives of quinolone and isoquinoline. This monograph is a valuable resource for undergraduate students of pharmacy and allied subjects.

  • Textbook of Neuropathology

    • 2nd Edition
    • Arthur Weil
    • English
    Textbook of Neuropathology, Second Edition covers some of the significant advances in understanding the theoretical and experimental aspects of neuropathology. Neuropathology is the study of the nervous tissue in disease and the determination of deviations of its structures from the normal. This edition is composed of 13 chapters, and begins with the description of the chemical changes occurring in the cell through autolysis and fixation. The subsequent chapters are devoted to studies on better understanding of the vitamin deficiencies, the discovery of the sulfonamides and their contribution to the therapy of meningitis, and the different forms of shock treatment applied to selected cases of neurosis and psychosis. The remaining chapters explore the contribution of neuropathological investigation in various medical conditions, including anemic softening, arteriosclerosis, inflammation, infections, intoxications, injuries, degenerative diseases, tumors, and congenital malformations. This book will be of use to neuropathologists and workers and researchers in the allied fields.

  • Metabolism and Regulation of Secondary Plant Products

    Recent Advances in Phytochemistry
    • 1st Edition
    • V. C. Runeckles + 1 more
    • English
    Recent Advances in Phytochemisty, Volume 8: Metabolism and Regulation of Secondary Plant Products covers papers from the 13th annual meeting of the Phytochemical Society of North America held on August 8-10, 1973, at the Asilomar State Park and Conference Center in Pacific Grove, California. The book discusses phenylalanine ammonia-lyase and phenolic metabolism; enzymology and regulation of flavonoid and lignin biosynthesis in plants and plant cell suspension cultures; and possible multienzyme complexes regulating the formation of C6-C3 phelonic compounds and lignins in higher plants. The text also describes photoregulation of phenylpropanoid and styrylpyrone biosynthesis in Polyporis hispidus; the nonprotein amino acids from plants; and the role of proteinase inhibitors in natural plant protection. The regulatory control mechanisms in alkaloid biosynthesis; the biochemistry of myoinositol in plants; and unusual fatty acids in plants are also considered. Phytochemists and people involved in the study of pomology will find the book useful.

  • The Nervous System

    Autonomic Nervous System Drugs
    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology: A Comprehensive Treatise, Volume IV: The Nervous System — Part D: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including how adrenergic drugs affect the heart and systemic circulation, metabolism, and adrenergic compounds. The selection first offers information on the effects of adrenergic drugs on the heart and systemic circulation. Topics include actions of adrenergic drugs, possible drug actions on the heart, epinephrine and arterenol, and other sympathomimetic drugs. The book then examines the effects of adrenergic compounds on pulmonary circulation, including physiologic considerations and general considerations of adrenergic compounds. The manuscript ponders on the effects of adrenergic agents on smooth muscles other than those of the vascular system and the effects of sympathomimetic amines and adrenergic blocking agents on metabolism. The book also touches on veratrum alkaloids and neurotoxins, as well as botulism, tetanus, therapeutic use, and chemistry of veratrum alkaloids. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

  • Oogenesis

    The Storage of Developmental Information
    • 1st Edition
    • Chr. P. Raven
    • G. A. Kerkut
    • English
    International Series of Monographs on Pure and Applied Biology, Volume 10: Oogenesis: The Storage of Developmental Information focuses on the processes, reactions, and transformations involved in oogenesis. The book first offers information on embryonic development as a communication problem, formation of the egg cells, and the egg nucleus during oogenesis. Topics include decoding of developmental information, egg membranes, oogenesis, phase of nuclear activity, cytochemistry of the nucleus, and the egg cell. The manuscript also ponders on the cytoplasm and its inclusions and the relationships between the egg cell and the auxiliary cells. The text elaborates on the metabolism of the oocyte, cortex, and polarity and symmetry. The book also examines the storage of developmental information and information theory and biology. Genotypical information, physical foundation of developmental biology, and information and finality are discussed. The manuscript is a dependable reference for readers interested in oogenesis.

  • Principles of Epidemiology

    A Self-Teaching Guide
    • 1st Edition
    • Lewis H. Roht + 2 more
    • English
    Principles of Epidemiology: A Self-Teaching Guide consists of a series of problem-solving exercises designed to introduce and guide readers toward an understanding of the principles and methods of epidemiology, rather than the epidemiology of specific diseases or subject areas such as ""infectious disease"" or ""chronic disease"" epidemiology. The guide has been formulated to be used by itself or as a supplement to standard textbooks. It illustrates and illuminates the principles and concepts of epidemiology and provides the reader an opportunity to practice the application of these principles in a logical sequence. The guide is divided into 14 exercises. Each exercise will help readers to understand principles or methods used by epidemiologist. Topics covered include the patterns of disease, populations at risk and risk assessment, screening for disease, investigation of an epidemic, etiology of disease, principles of causation, study design in epidemiologic investigation, data interpretation, and the uses and applications of epidemiology.

  • Rhythmic Phenomena in Plants

    • 2nd Edition
    • Beatrice M. Sweeney
    • English
    Rhythmic Phenomena in Plants, Second Edition focuses on the study of biological clocks in all kinds of plants, from unicellular algae to flowering trees. This book discusses the patterns of plant movement, parameters of rhythms and how to calculate them, and rhythms that match and do not match environmental periodicities. The mechanism of circadian timing, circadian rhythms in angiosperms, comparison between dinoflagellates and other rhythmic organisms, and semilunar and lunar rhythms are also elaborated. This publication likewise covers the measurement of day length in photoperiodism, circannian rhythms in plants, oscillations with short periods in leaves and roots, and streaming in a slime mold. This edition is valuable to biologists intending to contribute to the study of biological timing.

  • Eutrophication of Deep Lakes

    Proceedings of Seminar on Eutrophication of Deep Lakes Held on 19–20 June 1978 at Gjøvik, Norway
    • 1st Edition
    • S. H. Jenkins
    • English
    Eutrophication of Deep Lakes focuses on research and experiments that are deemed valuable to mitigate the eutrophication of lakes. Containing the contributions of authors who have continuously conducted studies in this field, the book proceeds by pointing out how the loading concept can serve as a basis in the control of eutrophication. This discussion is seconded by discussions on the factors affecting the eutrophication of freshwaters in Norway. Particularly given attention in this book is the phosphorous content of small and large lakes. The relationship of pollution and eutrophication is also noted. The large inputs of nutrients into lakes is emphasized, and then the application of the US OECD eutrophication study results to deep lakes is discussed. The book also points to the stage of eutrophication of lakes in Norway, and particularly concerns the effect of eutrophication on living organisms in lakes. A review of the toxic substances that affect these organisms is also presented. The text is a valuable source of information for researchers and readers who are interested in studying how eutrophication affects the natural composition of lakes; how this process affects life in lakes; and the control measures and processes that need to be taken to control it.

  • Contemporary Neurology

    • 1st Edition
    • M.J.G. Harrison
    • English
    Contemporary Neurology compiles a large series of papers on the commonest neurological problems. This book discusses the management of epilepsy, involuntary movements, nerve and muscle diseases, and multiple sclerosis. The areas on infections, cerebrovascular disease, trauma, intracranial pressure, and vertebral column are also elaborated. This text likewise describes medical procedures on how to do a lumbar and cisternal puncture. Other topics include headache in children, hyperventilation, dizziness, funny turns—neurological, dysarthria, facial pain, and nystagmus. The weakness of the legs, loss of memory, coma, brain death, complications of alcoholism, and stupor and akinetic mutism are also covered. This publication is valuable to clinicians and examination candidates preparing for the DPM, MRCP (UK) and Neurology/Psychiatry “Boards”.

  • Comparative Vertebrate Morphology

    • 1st Edition
    • Douglas Webster + 1 more
    • English
    Comparative Vertebrate Morphology provides a comprehensive discussion of vertebrate morphology. The structure-function concept at the level of organs and organ systems is fundamental to an understanding of comparative evolutionary morphology. It is upon these three interrelated aspects—structure, function, and evolution— that that contents of this volume have been organized and presented. The book opens with a discussion of general concepts on vertebrate evolution. This is followed by separate chapters on vertebrate phylogeny, skeletal components, the cranial and postcranial skeleton, muscular tissues, muscular system, and development of the integument, nervous tissues, sense organs, nervous system structure, nervous pathways, and endocrines. Subsequent chapters deal with the digestive, respiratory, circulatory, excretory and water balance, and reproductive systems. This book was designed to meet the needs of a one-semester course for students who have already had an introductory course in biology. It is assumed that the lectures will be supplemented by a laboratory with its own laboratory manual. The organization of the text allows the instructor to coordinate the laboratory and lecture portions of the course.

  • A Neurological Study of Newborn Infants

    Clinics in Developmental Medicine, No. 28
    • 1st Edition
    • David J. Beintema
    • English
    A Neurological Study of Newborn Infants considers the consistencies and inconsistencies of neonatal neurological signs. The possibility of a relationship between pre- and perinatal complications of pregnancy and later cerebral dysfunction has led to an increasing interest in the early detection of these defects in the newborn infant. This book is divided into nine chapters, and begins with a presentation of standardized procedures to obtain reliable information from the neurological examination. The next chapters deal with the developmental course of neurological signs during the first days of life. The final chapters discuss the potential effects of obstetrical and postnatal conditions on the developmental course and the consistency of neurological signs throughout the neonatal period. This book is an invaluable source for developmental biologists, neurologists, pediatricians, and obstetricians.

  • Recent Advances in Animal Nutrition – 1977

    Studies in the Agricultural and Food Sciences
    • 1st Edition
    • William Haresign + 1 more
    • English
    Recent Advances in Animal Nutrition-1977 presents papers that tackle the various areas of concerns in raising ruminants. The book contains a total of 11 studies that examine the factors affecting rumen fermentation. The text first covers EEC and feed compounding, and then proceeds to discussing the aspects of the biochemistry of rumen fermentation. Chapter 3 examines the influence of nitrogen and carbohydrate inputs on rumen fermentation. Chapter 4 talks about reducing the rate of ammonia release through alternative non-protein nitrogen sources. The fifth chapter describes the potential of protected proteins in ruminant nutrition. Next, the book discusses the manipulation of rumen fermentation. Chapter 7 covers the application of non-protein nitrogen, protected proteins, and rumen fermentation control. The next two chapters deal with broilers and turkeys. The eleventh chapter talks about predicting growth response in pigs, while the last chapter covers fish nutrition. The book will be most useful to both researchers and practitioners of animal related disciplines, such as agriculture and veterinary medicine.

  • Thin-Layer and Liquid Chromatography and Pesticides of International Importance

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 7
    • 1st Edition
    • Joseph Sherma + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume VII: Thin-Layer and Liquid Chromatography Pesticides of International Importance covers information on the greatly expanded version of thin-layer chromatography and high-speed liquid chromatography. The book also discusses the formulation and residue analyses of individual compounds grouped according to uses, e.g., insecticides, herbicides, fungicides, and rodenticides. Toxicologists and people in agricultural chemicals and plant protection laboratories will find the book invaluable.

  • Plant Virology

    • 2nd Edition
    • R. E. F. Matthews
    • English
    Plant Virology, Second Edition, was written to cover the substantial developments in many areas of plant virology since the first edition was published. Advances have been made in all branches of the subject, but these have been most far reaching with respect to the structure of viruses and of their components, and in the understanding of how viral genomes are organized and how viruses replicate in cells. Significant developments have also occurred in the understanding of how viruses are transmitted by invertebrates and in the application of control measures for specific diseases. The taxonomy of viruses has advanced significantly, and there are now 25 internationally approved families and groups of plant viruses. All these developments have required that most sections be entirely rewritten. This book is intended primarily for graduate students in plant pathology, plant virology, general virology, and microbiology, and for teachers and research workers in these fields. It should also prove useful to some people in related disciplines—molecula... biologists, biochemists, plant physiologists, and entomologists.

  • Studies in Neurolinguistics

    • 1st Edition
    • Haiganoosh Whitaker + 1 more
    • English
    Studies in Neurolinguistics, Volume 3 presents detailed case histories, multi-subject experimental studies, literature reviews, and research papers that employ a variety of experimental and observational techniques. This volume contains seven chapters that focus on a wide range of research in the field of neurolinguistics. Chapter 1 discusses the various approaches to the problem of auditory comprehension in aphasia. A survey of the world's literature on bilingualism and aphasia is provided in chapter 2. The third chapter examines the different models and explanations for conduction aphasia. Chapter 4 provides a synthesis of the anatomic, physiologic, and behavioral research on the role of the limbic system in human communication. Chapter 5 presents a model of individual differences in hemispheric functioning, in which a number of theories about the left and right hemispheres are analyzed and compared. Chapter 6 shows how different levels of language are revealed. The last chapter addresses "The Question of Electrophysiological Asymmetries Preceding Speech" in a study of the readiness potentials over the motor and premotor regions in eight subjects. Linguists, psychologists, and neurologists will find the book highly informative.

  • Neuro-Psychopharmacology

    Proceedings of the 11th Congress of the Collegium Internationale Neuro-Psychopharmacologicum, Vienna, July 9-14, 1978
    • 1st Edition
    • B. Saletu + 2 more
    • English
    Neuro-psychopharmaco... covers the proceedings of the 11th Congress of the Collegium Internationale Neuro-psychopharmaco... held in Vienna on July 9-14, 1978. The book focuses on the processes, methodologies, and approaches in neuropsychopharmacol... The selection first offers information on the long-lasting effects of electroconvulsive therapy (ECT) on monoaminergic mechanisms and enhanced monoamine behavioral responses following repeated electroconvulsive shock to rats and their relevance to ECT. The book also underscores the ECT effects on mineral metabolism and neuroendocrine function. The publication reviews the genetic components in the mechanism of action of lithium; genetics and lithium ion metabolism in affective disorders; and pharmacogenetics and the pharmacologic challenge strategy in clinical research. The text also examines the influence of peptides in affective disorders and HLA antigens in affective disorders and cycloid psychoses. Discussions also focus on the biological and clinical basis of the therapeutic effects of benzodiazepines; effects of benzodiazepines on the electrical activity of the central nervous system; and diazepam metabolism in healthy subjects and patients with heart failure, renal failure, and hepatic cirrhosis. The selection is a dependable reference for readers interested in neuropsychopharmacol...

  • Genesis and Evolutionary Development of Life

    • 1st Edition
    • A. I. Oparin
    • English
    Genesis and Evolutionary Development of Life discusses the present state of thought on the origin and development of life. The book contains six chapters and begins with a brief history of attempts to solve the problem of the origin of life. This is followed by separate chapters the discuss the following events: the initial stages in the evolution of carbon compounds; formation of the "primitive soup"; origin of prebiological systems; evolution of "protobionts" and the origin of the first organisms; and the further evolution of the first organisms.

  • International Review of General and Experimental Zoology

    Volume 2
    • 1st Edition
    • William J. L. Felts + 1 more
    • English
    International Review of General and Experimental Zoology, Volume 2 is a collection of world literature concerning developments in general and experimental zoology. This book is composed of six chapters, and begins with a survey of the biochemical and serological techniques and their application in experimental taxonomy. The succeeding chapters review the field of general and comparative endocrinology in lower vertebrates, as well as the problems of understanding the fine structure of the synaptic cleft of presumed chemically transmitting synapses. These topics are followed by discussions on structural and functional aspects of the avian lungs and air sacs; the metabolic aspect of heat transfer in biological systems; and the external energy transfer from the organism to the surrounding environment. The final chapter focuses on the experimental studies of neurocranium morphology and growth. This book will prove useful to zoologists and taxonomists.

  • Calcium and Cell Function

    • 1st Edition
    • Wai Yiu Cheung
    • English
    Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonami... as calmodulin antagonists, phophorylase kinase, and phospholipidsensitiv... calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.

  • Recent Developments in Ruminant Nutrition

    • 1st Edition
    • W Haresign + 1 more
    • English
    Recent Developments in Ruminant Nutrition presents papers that discuss the advancement of the different areas of ruminant nutrition. The book is comprised of 20 chapters that cover topics, such as reproduction, diet, and nutrition. The coverage of the text includes growth stimulation in ruminants; protein quantity and quality for the U.K. dairy cow; and complete-diet feeding of dairy cows. The book also covers rumen fermentation related topics, such as influence of nitrogen and carbohydrate inputs on rumen fermentation; aspects of the biochemistry of rumen fermentation and their implication in ruminant productivity; and manipulation of rumen fermentation. The text will be of great use to researchers and professionals in the animal husbandry industry.

  • Peripheral Neuropathies

    Proceedings of the International Symposium on Peripheral Neuropathies Held in Milan, Italy, on June 26–28, 1978
    • 1st Edition
    • N. Canal + 1 more
    • English
    Peripheral Neuropathies compiles lectures presented at the Symposium on Peripheral Neuropathies held in Milan, Italy on June 26-28, 1978. This book covers the basic problems in peripheral nerve pathology; axonal transport; neuropathies in chronic renal failure; peripheral neuropathies in diabetes; compression neuropathies; and metabolic, genetic, and inflammatory neuropathies. This text also discusses topics such as filamentous inclusions in Schwann cell nuclei; autonomie dysfunction and myokymia in gold neuropathy; study of the effect of gangliosides on experimental carbon disulfide neuropathy; and peripheral nerve changes in Refsum's disease before and after treatment. This compilation is a useful source of information for students and researchers conducting investigative work on peripheral neuropathy.

  • Cells and Tissues

    • 2nd Edition
    • Arthur W. Pollister
    • English
    Physical Techniques in Biological Research, Volume III, Part A: Cells and Tissues focuses on improvements and innovations in physical techniques involved in biological research on cells and tissues. The selection first offers information on phase contrast and interference microscopy in cytology and birefringence and dichroism of cells and tissues. Topics include observational methods and results, quantitative techniques, nerve and muscle fibers, chloroplasts, cytoplasm, and nucleus. The book then examines X-ray microscopy and X-ray absorption analysis, including theoretical considerations of X-ray microscopy of biological materials and absorption and production of X-rays. The publication ponders on microtomy and manometric techniques for single cells and electron microscopy of microorganisms. Discussions focus on Cartesian diver respirometers, capillary respirometers, preliminary preparation of materials for drying, and techniques for studying dried specimens. The selection is highly recommended for students and readers interested in the physical techniques used in biological research.

  • Mechanisms of Drug Resistance in Neoplastic Cells

    Bristol-Myers Cancer Symposia, Vol. 9
    • 1st Edition
    • Paul V. Woolley + 1 more
    • English
    Bristol-Myers Cancer Symposia, Volume 9: Mechanisms of Drug Resistance in Neoplastic Cells provides information on both basic scientific and clinical studies on the causes and implications of tumor cell resistance to common antineoplastic agents. The book describes the colon cancer as a model for resistance to antineoplastic drugs; mathematical modeling of drug resistance; and the mechanism of induced gene amplification in mammalian cells. The text also discusses the cellular concomitants of multidrug resistance; resistance to alkylating agents; and the phosphoprotein and protein kinase C changes in human multidrug-resistant cancer cells. Novel drugs that affect glutathione metabolism; the regulation of genes encoding drug-metabolizing enzymes in normal and preneoplastic tissues; and the relevance of glutathione S-transferases to anticancer drug resistance are also considered. The book further tackles the cellular resistance to cyclophosphamide; the preclinical and clinical experiences with drug combinations designed to inhibit DNA repair in resistant human tumor cells; and the modification of the cytotoxicity of DNA-directed chemotherapeutic agents by polyamine depletion. The text also demonstrates multidrug resistance and the circumvention of resistance. Oncologists, molecular biologists, biochemists, geneticists, and pharmacologists will find the book invaluable.

  • Toxic Phosphorus Esters

    Chemistry, Metabolism, and Biological Effects
    • 1st Edition
    • Richard D. O'Brien
    • English
    Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.

  • Pharmacology of Antihypertensive Drugs

    • 1st Edition
    • P.A. Van Zwieten
    • English
    Handbook of Hypertension, Volume 3: Pharmacology of Antihypertensive Drugs presents the biological and clinical knowledge in the field of hypertension. This book discusses the fundamental pharmacology of antihypertensive drugs. Organized into 12 chapters, this volume begins with an overview of the classification of antihypertensive mechanisms of drugs. This text then examines the effects of antihypertensive drugs in animal models and discusses the importance of these models and responses to human hypertension. Other chapters consider the pharmacological basis for the treatment of hypertension. This book discusses as well the various classes of antihypertensive drugs, which depends on two factors. The final chapter deals with the inhibitors of angiotensin-converti... enzyme, which are essential in the drug treatment of hypertensive disease. This book is a valuable resource for clinicians, pharmacists, physiologists, epidemiologists, biological scientists, and general practitioners. Clinical investigators and medical students will also find this book extremely useful.

  • Additive Migration from Plastics Into Food

    • 1st Edition
    • T. R. Crompton
    • English
    Additive Migration from Plastics Into Food examines the intrusion of foreign chemicals into food via additives present in plastics packaging and the toxic hazards they pose to consumers. This book shows how direct contact between the packed commodity and the plastic is likely to result in the transfer of polymer additives, adventitious impurities such as monomers, catalyst remnants, and residual polymerization solvents, and low-molecular-weight polymer fractions from the plastic into the packaged material. This book is comprised of nine chapters and begins with a discussion on the various types of plastics used in food packaging as well as the types of substances present in the plastic that might migrate into the food. Subsequent chapters review world literature on extraction testing and the analysis of extractants. The determination of various types of polymer additives and residual monomers in extractants of liquid foodstuffs and beverages, solid foods, edible oils, and fatty foodstuffs is considered. The final chapter looks at the legal requirements concerning the use of additives in food-grade plastics in various countries. This monograph will be of interest to those in the plastics industry, food and beverage packaging industry, and large retail outlets such as supermarkets, along with medical and public health officials, legislators, environmentalists, and the general public.

  • Plant Biochemistry

    • 1st Edition
    • James Bonner + 1 more
    • English
    Plant Biochemistry focuses on the biological processes involved in plants, particularly noting metabolism, electron transport, biogenesis, and germination. The manuscript first offers information on the substructures and subfunctions of plant cell, including cell and subcell, enzymes, ribosomes, nucleus, cellular membranes, mitochondria and electron transport, chloroplast, and the substructure and function of the cell wall. The text then elaborates on basic metabolism. Enzymology, the path of carbon in respiratory metabolism, mono- and oligosaccharides, starch, insulin, and other reserve polysaccharides, and the biogenesis of the cell wall are discussed. The publication explains plant metabolism and control. Discussions focus on plant acids, alkaloid biogenesis, coumarins, phenylpropanes, and lignin, ethylene and polyacetylenes, steroids, and seed development and germination. The book is a valuable source of information for students or professional workers in the plant sciences.

  • The Saccharine Disease

    Conditions Caused by the Taking of Refined Carbohydrates, Such as Sugar and White Flour
    • 1st Edition
    • T. L. Cleave
    • English
    The Saccharine Disease, Conditions Caused by the Taking of Refined Carbohydrates, such as Sugar and White Flour contends that the causation of these conditions has been obscured through confusing distinctions between unnatural, refined carbohydrates and that of natural, unrefined carbohydrates like fruits and whole meal flour. The author notes that all the foregoing conditions are really the manifestations of a single master-disease—that many of the major diseases of modern societies are caused by consuming unreasonable amounts of refined carbohydrate foods. The author discusses that in the short time that man has changed his diet, evolutionary adaptation is left behind. He gives two rules to prevent and arrest all saccharine disease manifestations: Do not eat any food unless you definitely want it, and avoid eating white flour or white sugar. These two rules will prevent gastric or duodenal ulcer, diabetes, coronary disease, constipation, complications of varicose veins, hemorrhoids, E. coli infections, obesity, and some skin conditions, As a retired Surgeon-General of the Royal Navy, the author bases his assumptions on evolutionary, epidemiological, and other scientific or historical work. This book can give insights to dieticians, food researchers, nutritionists, people on diet, and general medicine practioners.

  • Psychobiological Aspects of Cognitive Growth

    • 1st Edition
    • Reuven Kohen-Raz
    • English
    Psychobiological Aspects of Cognitive Growth elucidates the psychobiological aspects of cognitive development. The goals of this book are limited to a description of what may be defined as ""borderline"" phenomena of cognitive development. These are phenomena that can be observed and measured behaviorally, and also can be conveniently investigated by neurophysiological, genetic, and biological methods. The book begins with a review of ""basic approaches"" to the problems of psychobiological interaction in cognitive processes. It then presents major theoretical contributions of prominent authors to this subject, namely, Werner's sensoritonic theory, Rothschild's model of the biosemiotic structure of the nervous system, and Piaget's psychobiological interpretations of intellectual growth. This is followed by a general discussion of psychobiological aspects of cognitive development in infancy, and a report on physical correlates of school readiness, including some investigations on relations between static balance ability and reading skill. After a presentation of findings and theoretical considerations related to effects of birth season on physical and mental growth, the final chapter summarizes three studies on the impact of physiological pubertal maturation on mental achievements at adolescence.

  • Specific Applications

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 16
    • 1st Edition
    • Joseph Sherma
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume XVI: Specific Applications presents analytical methodology for insecticides (ethoprop, fenoxycarb, fenvalerate) and five herbicides (chlorimuron ethyl, chlorsulfuron, glyphosate, metsulfuron methyl, sulfometuron methyl). The book discusses the determination of two important pesticide classes, anticoagulant rodenticides and fumigants, and the determination of other pyrethroid. Toxicologists and people involved in pesticide analysis will find the text invaluable.

  • Herbicides

    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Vol. 4
    • 1st Edition
    • Gunter Zweig
    • English
    Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume IV: Herbicides contains detailed analytical procedures for analysis of 30 different herbicides and plant growth regulators. Each chapter of this 27-chapter volume covers the chemical and biological properties, history of development, methods of synthesis, and modified residue methods for different crops. Each chapter presents first the general information, followed by intensive discussion of the methods of occurrence and residue analysis. Methods of analysis covered in each chapter include chemical methods, gas-liquid chromatography, colorimetry, and enzymatic techniques. Agriculturists, analytical chemists, and toxicologists will find this book rewarding.

  • The Flowering Process

    • 1st Edition
    • Frank B. Salisbury
    • P. F. Wareing + 1 more
    • English
    The Flowering Process covers the physiological processes involved in the conversion from the vegetative to the reproductive state in higher plants. This book is composed of ten chapters, and begins with a description of the biological framework of flowering. The succeeding chapters deal with the link between ecology and the flowering process and the low temperature promotion of flowering. These topics are followed by discussions on methods of experimentation with cocklebur and the preparation of plant for response to photo period. Other chapters describe the effect of light, pigment, and timing on flowering process. The final chapters consider the synthesis, movement, and action of the flowering hormone. This book will prove useful to graduate students with subjects related to the mechanisms of flowering.

  • Agrarian Development in Peasant Economies

    The Commonwealth and International Library: Agriculture and Forestry Division
    • 1st Edition
    • Eric Clayton
    • M. McG. Cooper
    • English
    Agriculture and Forestry Division, Volume 2: Agrarian Development in Peasant Economies: Some Lessons from Kenya tackles various areas of concerns in agriculture in the context of peasant economy. The title provides examples from the Kenyan agrarian development policies. The text first covers concern in improving agricultural production, and then proceeds to tackling post-war Kenya. Next, the selection talks about Kenyan agrarian revolution, along with the economics and features of peasant agriculture. The sixth chapter discusses government and agrarian development, while the seventh chapter details further problems of agrarian reform. The book will be of great interest to political scientists, economists, agriculturists, and sociologists.

  • Engström-Finean Biological Ultrastructure

    • 2nd Edition
    • J. B. Finean
    • English
    Engström-Finean Biological Ultrastructure, Second Edition, looks upon biological phenomena essentially as patterns of physical and chemical events organized in space and time. It attempts to describe the spatial aspects of this organization, emphasizing in particular the fundamental roles of individual types of molecules. It also introduces a minimum background of fundamental structural information and of techniques so as to aid in the appreciation of the significance of experimental data. The plan of the book in the present edition remains unchanged but the tremendous advances of recent years have necessitated changes in emphasis in the treatment of methods and fundamentals of structure and a complete reappraisal of biological ultrastructure. Key topics discussed include methods in ultrastructural research, the principles of molecular structure; the role of proteins, nucleic acids, lipids, carbohydrates, mineral salts; and the role of ultrastructure in biology and medicine.

  • Toxicology

    Mechanisms and Analytical Methods
    • 1st Edition
    • C. P. Stewart + 1 more
    • English
    Toxicology: Mechanisms and Analytical Methods, Volume II provides an account of the general methods of chemical analysis available to the toxicologist, discussion of the principles on which they are based, and a survey of the material to which they are applied. The volume supplements the methods presented in the first volume. It provides specific examples of general procedures; considers the important groups of poisons; arranges the order of extraction from biological material; and discusses the methods for identifying and determining the members of each poison group. The book will be invaluable to toxicologists, clinical chemists, and biochemists.

  • Mechanisms of Animal Discrimination Learning

    • 1st Edition
    • N. S. Sutherland + 1 more
    • English
    Mechanisms of Animal Discrimination Learning provides a review of the field of animal discrimination learning, with discussions into other areas such as generalization, partial reinforcement, and some aspects of comparative psychology. This book elaborates the origins of continuity-noncontin... controversy, analysis of attentional learning, Lashley and Wade's account of generalization, and evidence for a two-process analysis of the ORE. The reversal and nonreversal shifts, response unit hypothesis, inconsistent reinforcement and extinction of choice behavior, and aims and problems of comparative psychology are likewise described This text likewise covers the Zeaman and House model, Lovejoy's Model III, determinants of generalization gradients, cognitive dissonance hypothesis, and theoretical relevance of comparative psychology. This publication is a good source for biologists and researchers concerned with animal discrimination learning.

  • Cytogenetics of Cells in Culture

    • 1st Edition
    • R. J. C. Harris
    • English
    Cytogenetics of Cells in Culture documents the proceedings of a symposium that aimed to not only establish guideposts to the direction of the most recent progress in the rapidly developing field of cybegenetics, but to cross-pollinate, in the best Mendelian tradition, the thinking of widely recognized leaders in this field with the current ideas of their colleagues, within the intimacy of this small meeting. The contributors to this symposium emphasized (1) new techniques to detect patterns of DNA replication, to better understand cellular control mechanisms, and to perform chromosome analyses with automated instrumentation; (2) the effects of cell hybridization and of noxious substances such as radiation, chemical agents, and viruses on chromosomal patterns; and (3) the influence of altered chromosomal complement on the survival of cells to long-term tissue culture or to ionizing radiation treatment. It is hoped that the products of the many stimulating discussions which ensued during the 3-day gatherings will stimulate increased vigor and proliferation of research by the participants. It is further hoped that the publication of this volume will infect the reader with new concepts and ideas which will eventually broaden views of cytogenetics.

  • Prostaglandins-Immunopharmacology

    Proceedings of the 7Th International Congress of Pharmacology, Paris 1978
    • 1st Edition
    • B. B. Vargaftig
    • English
    Advances in Pharmacology and Therapeutics, Volume 4: Prostaglandins-Immun... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of prostaglandins, their immunopharmacology, and their therapeutic applications. Topics covered range from the biochemistry of prostaglandins, thromboxanes, and prostacyclin to the pharmacology of blood platelets and pharmacological approaches to enhancement of immunity. This volume is comprised of 23 chapters and opens with a discussion on the discovery of prostaglandins and their possible biological functions, including platelet aggregation and adrenergic neurotransmission. The reader is then introduced to unstable metabolites of arachidonic acid in relation to thrombosis; pharmacological interference in biotransformation of arachidonic acid; participation of prostaglandins in inflammatory pain; and factors affecting the formation and actions of cyclic AMP in blood platelets. The following chapters explore the role of thymosin and the endocrine thymus in the maintenance of immune balance; effects of thymosin fraction 5 in cancer patients; and the immunoregulatory activities of non-toxic synthetic polyribonucleotides. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.

  • Minireviews of the Neurosciences from Life Sciences

    • 1st Edition
    • Bernard B. Brodie + 1 more
    • English
    Minireviews of the Neurosciences from Life Sciences is a collection of minireviews of research in the neurosciences and originally published by the Journal of Life Sciences. These minireviews cover a wide range of topics such as the function and organization of the chromaffin vesicle; taste receptor proteins; the role of cyclic nucleotides in visual excitation; and regulation of tryptophan and tyrosine hydroxylase. Comprised of 34 chapters, this volume begins with a discussion on Na,K-ATPase, followed by an analysis of the function and organization of the chromaffin vesicles of the adrenal medulla. Subsequent chapters focus on the nerve growth factor and the acetylcholine receptor; sympathetic regulation of thyroid hormone secretion; the role of cyclic AMP in the action of antidiuretic hormone on the kidney; and neurochemical correlates of synaptically active amino acids. The role of calcium in the central effects of biogenic amines is also examined, along with the brain mechanisms underlying motor control, molecular coding of memory, and opiate receptors. This book should be of value to teachers, researchers, and students.

  • Advances in Smoking of Foods

    Plenary Lectures Presented at the International Symposium on Advances in Smoking of Foods, Warsaw, Poland, 8 - 10 September, 1976
    • 1st Edition
    • A. Rutkowski
    • English
    Advances in Smoking of Foods covers the plenary lectures presented at the International Symposium on Advances in Smoking of Foods, held in Warsaw, Poland, on September 8-10, 1976. The book focuses on the processes involved in the smoke curing of foods, as well as on the analysis of the production of smoke and compounds found in it. The compilation first offers information on the phenomena of quality in the smoke curing process, including the history, reviews, and advances of the process. The book then evaluates the physical and chemical processes involved in the production and application of smoke. The processes considered in the production of smoke from wooden materials are underscored. The text presents an analysis of smoke and smoked food, wherein it is posed that wood smoke is composed of compounds formed by the pyrolysis of wood constituents such as cellulose, hemicellulose, and lignin. Polycyclic hydrocarbons and phenolic compounds are discussed. The book also explains the contributions of smoke compounds to sensory, bacteriostatic, and antioxidative effects in smoked foods; facts and legislation regarding polycyclic aromatic hydrocarbons in smoked foods; and concepts in technology and design of machinery for production and application of smoke in the food industry. The selection is a vital source of information for readers wanting to study the smoke curing of foods.

  • General Photobiology

    • 1st Edition
    • Donat-Peter Hader
    • English
    Photobiology is an interdisciplinary science which has undergone a dramatic development in the past few years. This comprehensive new textbook brings together all the information required by workers and students in the field, from the atomic to the organismal level. The initial chapters comprise a comprehensive introduction to the terminology and include a detailed description of the photochemical reactions involved. The main part of the book covers all the classical photochemical topics and whilst not trying to be encyclopedic in coverage, does present numerous relevant examples. By bringing together the wide breadth of knowledge involved in the understanding of photobiology, this book will be of immense use to all those involved.

  • Drug Testing

    • 1st Edition
    • John Fay
    • English
    Drug Testing focuses on the contributions of drug testing in the identification of the state of drug abuse and the implementation of policies and regulations making drug use unacceptable either socially or in the workplace. The book first gives an overview of drug-testing policy, facilitating drug testing and treatment, challenges to drug-testing programs, and state, local, and federal legislation on drug testing. The text then defines the problem of drug abuse, including dimensions of abuse, defining the problem and the needs of employers, employing a drug abuse survey, and treatment modalities. The manuscript ponders on the development of a drug-testing policy, education of employees, and training of supervisors. Discussions focus on the nature of learning, principles of supervision, training process, program implementation, basic assumptions, final policy content, and problematic issues. The implementation of a drug-testing program, collection of specimens for drug testing, and understanding the drug testing program are also underscored. The publication is a valuable reference for readers interested in drug testing policies, treatment, and effects of drug abuse in the workplace.

  • Aging and Other Model Systems

    • 1st Edition
    • Bert M. Zuckerman
    • English
    Nematodes as Biological Models, Volume 2: Aging and Other Model Systems contains discussions on free-living nematodes as biological models for pharmacologic and toxicant testing, and for studies on gerontology and nutrition. The book presents specific chapters that cover topics on nematodes as models to study aging; nematodes as nutritional models; physiology and morphology of nematodes; and models and mechanisms on longevity and survival in nematodes. Geneticists, cell and developmental biologists, neurologists, endocrinologists, toxicologists, nutritionists, and gerontologists will find the book invaluable.

  • Modern Analytical Techniques

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 14
    • 1st Edition
    • Gunter Zweig + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume XIV: Modern Analytical Techniques covers an updated treatment of the most frequently used techniques for pesticide analysis, i.e., thin-layer chromatography, gas chromatography (packed and capillary columns), high-performance liquid chromatography, and mass spectrometry. People involved in the analysis of pesticides will find the book useful.

  • Animal Communication by Pheromones

    • 1st Edition
    • H. H. Shorey
    • English
    Animal Communication by Pheromones describes how the behavior of animals is controlled and influenced by pheromone communication. This book describes the mechanism through which the social animals interact with each other and by which they are organized according to their relative statuses and functions. The text then describes the pheromonal communication system; the mechanisms of movement and orientation to pheromone sources; and recognition, aggregation, and dispersion pheromone behaviors. The sex pheromone behavior; the environmental and physiological control of sex pheromone behavior; and the aspects of pheromones as stimulators or inhibitors of aggression are considered. The book further tackles sex pheromones; reproductive isolation; and the evolution of pheromonal communication. Entomologists and animal scientists will find the book useful.

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