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Books in Life sciences

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  • Public Health and Toxicology Issues in Drug Research, Volume 2

    Toxicity and Toxicodynamics
    • 1st Edition
    • Rakesh Kumar Tekade + 1 more
    • English
    Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two examines implications on public health and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments. The book cover topics on pharmacokinetics and toxicokinetics, such as population pharmacokinetics/tox... the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. In addition, it investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body.Final sections discuss the mechanistic pathways of food toxicants and illustrate the molecular mechanisms of the chemopreventive role of dietary phytochemicals. Ethical, legal, societal, and professional issues in toxicology round off coverage, making this a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

  • Novel Formulations and Future Trends

    Recent and Future Trends in Pharmaceutics, Volume 3
    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students.New technologies are also explored including 3D printing and computational pharmaceutics.

  • Treatise on Estuarine and Coastal Science

    • 2nd Edition
    • Daniel Baird + 1 more
    • English
    Treatise on Estuarine and Coastal Science, Seven Volume Set is the most up-to-date reference work for system based coastal and estuarine ecosystem science and management. It addresses the big issues facing the estuaries and coastal zone; in particular how to best use multi- and inter-disciplinary science to ensure the sustainability of the environment. It focusses on the need to protect and maintain the natural functioning of the estuaries and coasts worldwide while delivering the ecosystem services from which society extract goods and benefits.Structured chapters, written by leaders in the field, include reference lists and additional reading, copious diagrams, case-studies, and especially provide synthesis diagrams and conceptual models of complex issues. The Treatise covers both the natural and social sciences, serving a wide audience which ranges from undergraduate students to established researchers and practitioners. The work avoids autecological studies but focusses on inter-linked physical-chemical-bi... processes and associated socio-economic issues in the coastal zone. It examines estuaries and coasts, and their interactions and feedbacks with humanity, from the inland catchment/river basin to the ocean shelf.The new edition builds on and expands the previous version with significant updates and a whole new section on Climate Change and Coastal Ecosystems, covering the resistance and resilience of the estuaries, coasts and other transitional habitats to climate change, thereby determining changes and responses needed over the coming decades.

  • Advanced Vaccination Technologies for Infectious and Chronic Diseases

    A guide to Vaccinology
    • 1st Edition
    • Vasso Apostolopoulos + 2 more
    • English
    Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

  • Microbial Diversity in the Genomic Era

    Functional Diversity and Community Analysis
    • 2nd Edition
    • Surajit Das + 1 more
    • English
    Microbial Diversity in the Genomic Era: Functional Diversity and Community Analysis, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. The book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Sections provide a broad overview of microbial genomics research and microbiome directed medicine and update on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions. Step-by-step methodologies are provided for key techniques, along with applied case studies that break down recent research studies into practical components, thus illuminating pathways for new studies across the field.

  • Computational Intelligence in Protein-Ligand Interaction Analysis

    • 1st Edition
    • Bing Wang + 2 more
    • English
    Computational Intelligence in Protein-Ligand Interaction Analysis presents computational techniques for predicting protein-ligand interactions, recognizing protein interaction sites, and identifying protein drug targets. The book emphasizes novel approaches to protein-ligand interactions, including machine learning and deep learning, presenting a state-of-the-art suite of skills for researchers. The volume represents a resource for scientists, detailing the fundamentals of computational methods, showing how to use computational algorithms to study protein interaction data, and giving scientific explanations for biological data through computational intelligence. Fourteen chapters offer a comprehensive guide to protein interaction data and computational intelligence methods for protein-ligand interactions.

  • Anoxygenic Phototrophic Bacteria

    • 1st Edition
    • Keizo Shimada + 1 more
    • English
    Anoxygenic Phototrophic Bacteria is a comprehensive overview of phototrophic bacteriacovering the following: overview of photosynthesis and phototrophic bacteria; systematicsand characteristics of each taxon; ecology and cultivation; photosynthetic electrontransfer systems; metabolism; pigments and lipids; light-harvesting systems and reactioncenters; photosynthetic genes and regulation of gene expression; origin and evolution ofphotosynthesis; and the utilization of phototrophic bacteria.Chapters are written by some of Japan’s leading researchers in the area, providing researchersin photosynthesis, bacterial physiology, microbial ecology, artificial photosynthesis,bioph... biochemistry, industrial chemistry a highly detailed, up-to-date and thoroughlycross-refe... book in this interdisciplinary area. With very few books being published overthe last 25 years on the topic, this book especially fills a crucial need for young researchersand those working at the margins of interdisciplinary fields.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 119
    • English
    Advances in Clinical Chemistry, Volume 119, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. Topics covered in this new release include Advances in Endotoxin Analysis, SARS-CoV-2 detection and surveillance, Osteopontin in Cancer, Gastrointestinal Hormones: History, Biology, and Measurement, Natriuretic Peptide Testing Strategies in Heart Failure: a 2023 Update, and Defining Allowable Total Error Limits in the Clinical Laboratory.

  • G4 biology

    • 1st Edition
    • Volume 695
    • English
    G4 Biology, Volume 695 in the Methods in Enzymology series, highlights high value topics such as Assays to measure G4 resolution by DNA helicases, In gel staining methods of G4 DNA and RNA structures, Methods to probe the folding pathways of four-stranded intercalated cytosine-rich motifs at single base-pair resolution, Analyzing the effect of transcription coupled R-loop formation on G4 formation, Integrated Structural Biology for the study of higher-order G4 structures, Advancing the Study of Protein-G4 Interactions in DNA Repair: Insights from Biolayer Interferometry and Circular Dichroism Spectroscopy, Immunofluorescence microscopy (IF) of G-quadruplex and R-loops, and more.Additional chapters delve into Production of the anti-G-quadruplex antibody BG4 for efficient ChIP-seq and CUT&Tag analysis: from plasmid quality control to validation, Utility of intercalator displacement assays for screening of ligands for i-motif DNA structures, Potentiometric titrations to study ligand interactions with DNA i-motifs, Towards Profiling of the G-Quadruplex Targeting Drugs in the Living Human Cells Using NMR Spectroscopy, and Identification of bona fide G4-binding proteins, Observing Pif1 opening dsDNA and G4 in real time by manipulation under magnetic tweezers, and in vivo detection of DNA secondary structures using Permanganate/S1 Footprinting with direct adapter ligation and sequencing (PDAL-Seq).

  • Open Electronic Data Capture Tools for Medical and Biomedical Research and Medical Allied Professionals

    • 1st Edition
    • Ashish Pundhir + 2 more
    • English
    Open Electronic Data Capture Tools for Medical and Biomedical Research and Medical Allied Professionals explains the step-by-step of collecting and treating research data in a didactic manner. The book discusses four freely available data capture tools whose common feature is data collection and entry being done simultaneously rather than separately, thus saving resources and minimizing potential errors. It highlights the comparative features of each data capture tool, helping readers to understand the advantage and disadvantage of each one to decide which tool can be used to fulfill their needs.This is a valuable resource for researchers, students, and members of the biomedical and medical fields who need to learn more about data mining and management to improve the quality of their research work.

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