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Books in Life sciences

  • Novel Drug Delivery Systems in the management of CNS Disorders

    • 1st Edition
    • Pooja A Chawla + 4 more
    • English
    Novel Drug Delivery Systems in the Management of CNS Disorders offers a comprehensive source of information on delivering drugs to the central nervous system to treat various diseases and conditions. The book covers a wide range of CNS disorders, including epilepsy, Parkinson's, Alzheimer's, Huntington's, multiple sclerosis, schizophrenia, cerebral palsy, autism, ALS, and others.The book begins by presenting the foundations of drug delivery to the brain and addressing the associated challenges. It then delves into clinical trials and explores the future potential of the presented technologies.This reference is designed for drug delivery researchers in academia and corporations, providing them with the essential knowledge about overcoming the Brain-Blood Barrier and achieving targeted drug delivery to the central nervous system.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition

    Volume 2
    • 7th Edition
    • Volume 2
    • Roger N. Rosenberg + 1 more
    • English
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Seventh Edition provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. This volume includes new chapters on Von Hippel-Lindau disease, antisocial and violent behavior and Autism. A favorite of over four generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the previous edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large.

  • Bio Refinery of Wastewater Treatment

    Way to Generate Waste to Value
    • 1st Edition
    • Maulin P. Shah + 1 more
    • English
    Bio Refinery of Wastewater Treatment: Way to Generate Waste to Value focuses on the exploitation of various wastewater treatment technologies and microbial, chemical, and physical processes as tools for simultaneous value generation during treatment, degradation, detoxification, and stabilization of toxic and hazardous contaminants and restoring contaminated sites. The book provides recents advancements in integrative and cost-effective wastewater treatment strategies and stipulates all pros and cons of each strategy.Bio Refinery of Wastewater Treatment: Way to Generate Waste to Value is valuable to researchers and scientists, who are working in the field of effluent treatment plants/biodegradatio... of environmental contaminants for environmental protection and sustainable development.

  • Predictive Analytics using MATLAB(R) for Biomedical Applications

    • 1st Edition
    • L. Ashok Kumar
    • English
    Predictive Analytics using MATLAB(R) for Biomedical Applications is a comprehensive and practical guide for biomedical engineers, data scientists, and researchers on how to use predictive analytics techniques in MATLAB(R) for solving real-world biomedical problems. The book offers a technical overview of various predictive analytics methods and covers the utilization of MATLAB(R) for implementing these techniques. It includes several case studies that demonstrate how predictive analytics can be applied to real-world biomedical problems, such as predicting disease progression, analyzing medical imaging data, and optimizing treatment outcomes.With a plethora of examples and exercises, this book is the ultimate tool for reinforcing one’s knowledge and skills.

  • Stem Cells in Neurotoxicology

    • 1st Edition
    • Volume 12
    • English
    Stem Cells in Neurotoxicology, Volume Twelve in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Brain organoids as a translational model of human developmental neurotoxicity, Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence, Utilization of human stem cell/neural progenitor tests to examine neurotoxic impacts on differentiation, Characterization of neuronal and other cellular sub-types in human stem cell cortical neuron differentiations, Utility of human stem cell models to study persistent neurotoxicity, and Utility of human stem cell models to study chronic neurotoxicity.

  • Medical Image and Signal Analysis in Brain Research

    • 1st Edition
    • Volume 290
    • English
    Progress in Brain Research, Volume 290 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this release include Image Analysis for Spinocerebellar Ataxia Type 3, Brain structural network modular and connectivity alterations in subtype of patients with migraine, Brain Functional Networks and Structures that Categorize Type 2 Bipolar Disorder and Major Depression, Reinforcement Learning Classification in fNIRS Signal of Olfactory Stimulated, The method of brain-computer interface using the forehead instead of the visual area to receive SSVEP signals and signal processing, and more.Additional chapters cover The relationship between flash-induced SSVEP in DELTA frequency band and sleep, Enhancing Facial Feature De-Identification in Multi-Frame Brain Images: A Generative Adversarial Network Approach, Comparative Analysis of MRI Markers in Heat and Mechanical Pain Sensitivity, and Analysis of the Difference Between Alzheimer’s Disease, Mild Cognitive Impairment and Normal People by Using Fractal Dimensions and Small-World Network.

  • Neuroscience Research in Short-Duration Human Spaceflight

    • 1st Edition
    • Bader Shirah
    • English
    Neuroscience Research in Short-duration Human Spaceflight encapsulates a groundbreaking neuroscience portfolio conducted during the Axiom Mission 2 in May 2023, offering an examination of the effects of short-duration orbital spaceflight on aspects of the human brain. Addressing limitations in existing literature, the research includes astronauts of diverse ages, genders, and ethnic backgrounds, broadening the understanding of the impact of spaceflight on human physiology. A significant aspect of the suite of studies is the validation of two novel devices providing unprecedented information about the pupillary light reflex and neuroimaging in microgravity: automated pupillometry and functional near-infrared spectroscopy. The portfolio extends to explore spaceflight-associat... neuro-ocular syndrome, offering valuable contributions to the evolving field of space medicine. Furthermore, the research delves into the utilization of electroencephalograp... to monitor brain activity, acknowledging its potential in assessing cognitive health, stress levels, and mental workload in real time. Despite promising prospects, challenges in electroencephalograp... system adaptability within the International Space Station environment are highlighted, emphasizing the need for specialized design considerations. In addition, analysis is extended into the molecular biomarkers through minimally invasive blood monitoring. This book represents a pivotal advancement in space neuroscience, laying the foundation for safer space travel and fostering the development of monitoring tools crucial to observing adverse changes and potentially developing countermeasures that can aid in the establishment of a permanent human presence beyond Earth.

  • Inherited White Matter Disorders and Their Mimics

    • 1st Edition
    • Volume 204
    • English
    Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathie... often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping.This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable.

  • The Physics of Protein Structure and Dynamics

    When and Why Proteins Fold or Don’t Fold
    • 1st Edition
    • Reinhard Schweitzer-Stenner
    • English
    The Physics of Protein Structure and Dynamics looks at various aspects of protein structure and dynamics from a physico-chemical point of view. It goes into some depth regarding the description of non-covalent forces that determine the relative stability of folded and unfolded proteins. Anharmonic protein dynamics involving motions between different minima of a rugged Gibbs energy landscape is described in great detail. The book combines various aspects of the protein folding/unfolding processes with an overview of intrinsically disordered proteins, which have attracted considerable interest of the protein community over the last 25 years but are thus far underrepresented in classroom-oriented textbooks. The book looks at protein folding and intrinsically disordered proteins as heavily interrelated topics that need to be viewed together. Furthermore, it presents some basic physico-chemical aspects of protein/peptide self-assembly into nanoscale fibrils. Intrinsically disordered peptides and proteins play a major role particularly in aggregation and self-assembly processes that lead to various diseases (Alzheimer, Parkinson, Huntington, Mad-Cow). Therefore, the relevance of protein disorder for protein self-assembly deserves a closer look. Protein self-assembly cannot be separated from protein folding since it is frequently the product of misfolding. With regard to modern theories, the folding processes are linked to insights on protein dynamics and the discovered relationship between proteins and spin glasses.

  • Autism Autonomy

    In Search of Our Human Dignity
    • 1st Edition
    • Elizabeth B. Torres
    • English
    Autism Autonomy: In Search of Our Human Dignity provides a new and unifying methodological framework and discusses machine learning and biometrics techniques to diagnose, characterize, and treat patterns of sensory motor control underlying autism symptoms. With the hope of improving basic research in these areas, this volume will allow readers to design better interventions and provide awareness of a number of new technologies used in the autism field. Wearable bio-sensing technologies, machine learning, and AI methods are all discussed regarding their applications to provide better self-awareness, interaction, diagnosis, and prognosis.This volume is useful for researchers and clinicians interested in learning about these new technologies and how to enhance machine learning use in ASD for the betterment of patients.

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