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Books in Life sciences

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 56
    • English
    Advances in Insect Physiology, Volume 56, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists, with this new release focusing on the Effects of resource limitation on the strengths of tradeoffs in insect lifecycles, The circadian system in insects: cellular, molecular, and functional organization, Molecular Physiology of the Insect Midgut, The Cryptonephridic system in Lepidoptera, Subsocial insects and the physiology of parental care, Mechanisms regulating phenotypically plastic traits in wing polymorphic insects, and more.
  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates, Compact

    The Coronal Plates and Diagrams
    • 5th Edition
    • Keith B.J. Franklin + 1 more
    • English
    Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery.
  • Sweet Potato

    Chemistry, Processing and Nutrition
    • 1st Edition
    • Taihua Mu + 1 more
    • English
    Sweet Potato: Chemistry, Processing, and Nutrition presents foundational information, including identification, analysis, and use of chemical components from sweet potato in a variety of food and nonfood uses. Sweet potatoes can be easily propagated, are rich source of carbohydrates and functional components, and are highly productive, which makes them most suitable for production of staple and functional foods. With the increasing population and the challenges of providing healthy food to the world, there is an increasing consumer demand for new and better sweet potato products, particularly for those in developing countries. Providing a brief description of the specific sweet potato components, their role during processing and strategies for quality optimization, this book also explores novel methods of sweet potato starch, protein, and pectin modification providing students, researchers, and technologists working in the area of food science and others with the most recent information and state-of-the-art technology for developing new and beneficial uses of sweet potato.
  • Protein Modificomics

    From Modifications to Clinical Perspectives
    • 1st Edition
    • Tanveer Ali Dar + 1 more
    • English
    Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.
  • Mitochondrial Medicine

    A Primer for Health Care Providers and Translational Researchers
    • 1st Edition
    • Pankaj Prasun
    • English
    Mitochondrial Medicine: A Primer for Health Care Providers and Translational Researchers is an applied, holistic resource that addresses the evolving and multidisciplinary area of mitochondrial disease. The book discusses the fundamentals of mitochondrial medicine in humans, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role of mitochondria in common medical conditions, such as diabetes, heart failure and the full range of inherited mitochondrial diseases. Sections cover the genetic and biochemical basis of both mitochondrial DNA deletion syndromes and point mutation syndromes, their clinical presentation, treatment plans, genetic counseling, prenatal testing, and ongoing research. While providing a solid foundation in its topic area, each chapter in the book is written in an accessible format with illustrative case studies, thus making it a quick bedside or clinical laboratory reference.
  • Transgenerational Epigenetics

    • 2nd Edition
    • Volume 13
    • English
    Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.
  • Neural Network Modeling and Identification of Dynamical Systems

    • 1st Edition
    • Yury Tiumentsev + 1 more
    • English
    Neural Network Modeling and Identification of Dynamical Systems presents a new approach on how to obtain the adaptive neural network models for complex systems that are typically found in real-world applications. The book introduces the theoretical knowledge available for the modeled system into the purely empirical black box model, thereby converting the model to the gray box category. This approach significantly reduces the dimension of the resulting model and the required size of the training set. This book offers solutions for identifying controlled dynamical systems, as well as identifying characteristics of such systems, in particular, the aerodynamic characteristics of aircraft.
  • Advances in Biological Science Research

    A Practical Approach
    • 1st Edition
    • Surya Nandan Meena + 1 more
    • English
    Advances in Biological Science Research: A Practical Approach provides discussions on diverse research topics and methods in the biological sciences in a single platform. This book provides the latest technologies, advanced methods, and untapped research areas involved in diverse fields of biological science research such as bioinformatics, proteomics, microbiology, medicinal chemistry, and marine science. Each chapter is written by renowned researchers in their respective fields of biosciences and includes future advancements in life science research.
  • Noonan Syndrome

    Characteristics and Interventions
    • 1st Edition
    • Amrit P.S. Bhangoo
    • English
    Noonan Syndrome: Characteristics and Interventions provides an in-depth analysis on this disorder that pediatric endocrinologists and primary care clinicians can use to make sure they provide affected patients with an updated model of care and appropriate treatment. The book examines recent advances in understanding and treating short stature in Noonan Syndrome, along with the latest progress in growth hormone-dependent signaling pathways involved in short stature, one of the most frequent clinical manifestations. Chapters also address how patients with Noonan Syndrome undergo more than average surgical procedures and have a great bleeding risk. This must have reference for pediatric endocrinologists and practicing physicians will give them all the information they need on the topic.
  • EEG-Based Experiment Design for Major Depressive Disorder

    Machine Learning and Psychiatric Diagnosis
    • 1st Edition
    • Aamir Saeed Malik + 1 more
    • English
    EEG-Based Experiment Design for Major Depressive Disorder: Machine Learning and Psychiatric Diagnosis introduces EEG-based machine learning solutions for diagnosis and assessment of treatment efficacy for a variety of conditions. With a unique combination of background and practical perspectives for the use of automated EEG methods for mental illness, it details for readers how to design a successful experiment, providing experiment designs for both clinical and behavioral applications. This book details the EEG-based functional connectivity correlates for several conditions, including depression, anxiety, and epilepsy, along with pathophysiology of depression, underlying neural circuits and detailed options for diagnosis. It is a necessary read for those interested in developing EEG methods for addressing challenges for mental illness and researchers exploring automated methods for diagnosis and objective treatment assessment.
  • Sports and Energy Drinks

    Volume 10: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Sports and Energy Drinks, Volume 10 in The Science of Beverages series, is the first single-volume resource to focus on the science behind these beverages-for-purpos... products. As consumers seek ways to effectively replenish key nutrients after strenuous activity—while also balancing calories and vitamin intake—sports and energy drinks is one of the fastest growing markets in the industry. From protein to fruit, athlete to adolescent consumption, this book explores the key issues and challenges in developing products that meet consumer demand in a safe-and-effective manner. This series takes a multidisciplinary approach to help research and development professionals understand the scientific complexities of these unique beverages. As demand for sports and energy drinks is growing and with a more competitive market, this timely and useful resource will equip industry professionals with the tools they need to create new and innovative health-promoting products.
  • Milk-Based Beverages

    Volume 9: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Milk-Based Beverages, Volume 9 in The Science of Beverages series, presents current status, developments, and technologies for researchers and developers to meet consumer demand and understand consumer trends toward healthy drinks. This resource takes a multidisciplinary approach to address issues in safety and quality control, while also discussing the nutritional and functional information that professionals in the beverage industry need. The book presents a framework for researchers, product developers, engineers, and regulators in the beverages industry for understanding new research developments in milk-based products to meet industry needs in producing competitive products.
  • Companion and Complementary Diagnostics

    From Biomarker Discovery to Clinical Implementation
    • 1st Edition
    • Jan Trøst Jørgensen
    • English
    Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies.
  • New Approaches for Flavin Catalysis

    • 1st Edition
    • Volume 620
    • English
    New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superf... O2 and Superoxide Analogs, and more.
  • Climate Change and Agricultural Ecosystems

    Current Challenges and Adaptation
    • 1st Edition
    • Krishna Kumar Choudhary + 1 more
    • English
    Climate Change and Agricultural Ecosystems explains the causative factors of climate change related to agriculture, soil and plants, and discusses the relevant resulting mitigation process. Agricultural ecosystems include factors from the surrounding areas where agriculture experiences direct or indirect interaction with the plants, animals, and microbes present. Changes in climatic conditions influence all the factors of agricultural ecosystems, which can potentially adversely affect their productivity. This book summarizes the different aspects of vulnerability, adaptation, and amelioration of climate change in respect to plants, crops, soil, and microbes for the sustainability of the agricultural sector and, ultimately, food security for the future. It also focuses on the utilization of information technology for the sustainability of the agricultural sector along with the capacity and adaptability of agricultural societies under climate change. Climate Change and Agricultural Ecosystems incorporates both theoretical and practical aspects, and serves as base line information for future research. This book is a valuable resource for those working in environmental sciences, soil sciences, agricultural microbiology, plant pathology, and agronomy.
  • Sleep Deprivation and Cognition

    • 1st Edition
    • Volume 246
    • English
    Sleep Deprivation and Cognition, Volume 247, the latest release in the Progress in Brain Research series, covers the effects of sleep deprivation, with this new release featuring sections on the Impact of sleep deprivation on long-term memory, Adolescent sleep restriction effects on cognition and mood, Self- regulation and social behavior during sleep deprivation, Experiential decision-making and the effects of sleep loss, Sleep deprivation and dynamic attentional control, a Pharmacogenetic approach to understanding sleep deprivation and cognition, Neuroimaging of functional connectivity in the sleep-deprived brain: what does it tell us?, and more.
  • Telemedicine Technologies

    Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare
    • 1st Edition
    • D. Jude Hemanth + 1 more
    • English
    Telemedicine Technologies: Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare illustrates the innovative concepts, methodologies and frameworks that will increase the feasibility of the existing telemedicine system. The book also focuses on showcasing prototypes of remote healthcare systems, thus emphasizing the data processing side that is often recognized as the backbone of any telemedicine system.
  • 250 examens de laboratoire

    en pratique médicale courante
    • 13th Edition
    • René Caquet
    • French
    Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.
  • Inspiring Conversations with Women Professors

    The Many Routes to Career Success
    • 1st Edition
    • Anna Garry
    • English
    Inspiring Conversations with Women Professors: The Many Routes to Career Success provides stories behind the many paths to professorship taken by these featured women. It includes information on their diverse life stories and how they navigated the beginning, middle stages, and other parts of their careers, including unexpected paths, support and how they got hooked by science/their field. In addition, they discuss why they chose this career, the obstacles they encountered, and how they found a way forward. Each interview encapsulates the advice and practical solutions they give.
  • Human Embryos and Preimplantation Genetic Technologies

    Ethical, Social, and Public Policy Aspects
    • 1st Edition
    • E. Scott Sills + 1 more
    • English
    Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions.
  • The Little Black Book of Neurology

    • 6th Edition
    • Osama O. Zaidat + 2 more
    • English
    Widely known and well-respected, The Little Black Book of Neurology has been a thorough yet portable reference in this complex field for more than 30 years, presenting definitions, classifications, and guidance on diagnosis and management for a wide range of neurological disorders. The 6th Edition offers updated and expanded coverage of neuropharmacology and neuroimaging – plus a new, more user-friendly, fast-access format that makes the book ideal for quick clinical consultation or as a refresher for the Boards.
  • Les troubles du sommeil

    • 3rd Edition
    • Yves Dauvilliers
    • French
    La médecine du sommeil est une discipline récente et les manuels qui lui sont consacrés sont peu nombreux. Les troubles du sommeil et de l’éveil touchent pourtant une part importante de la population et ont de graves répercussions sur la santé physique et mentale, ainsi que sur la qualité de vie.La 3e édition de cet ouvrage de référence, entièrement mis à jour et agrémenté de questionnaires, d’échelles et d’un glossaire étendu :• fait le point sur le sommeil normal (aspects neurobiologiques et physiologiques chez l’enfant, l’adulte et le sujet âgé),• présente les différentes méthodes d’exploration,• propose une synthèse sur les multiples troubles (insomnie, hypersomnie, troubles du rythme circadien, parasomnie…),• établie le lien entre les troubles du sommeil et les spécialités médicales : neurologie, cardiologie, pneumologie, endocrinologie, pédiatrie, psychiatrie, ORL….Cet ouvrage s’adresse aux médecins généralistes et spécialistes. Ils y trouveront des réponses à leurs questions, ainsi que de nombreuses indications pour la prise en charge des patients et la prescription de traitements. Il s’adresse également à tous les professionnels de santé, chercheurs et étudiants désireux de s’ouvrir à un domaine encore peu enseigné dans les facultés et écoles.
  • Intracellular Signalling Proteins

    • 1st Edition
    • Volume 116
    • English
    Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.
  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B
    • 1st Edition
    • Volume 163
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases—30 Years Clinical Applications in China, and more.
  • Advances in Parasitology

    • 1st Edition
    • Volume 104
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 104, the latest in a series first published in 1963, contains comprehensive reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Leishmania Tropica, Extracellular Vesicles in Host-Parasite Interaction, Cathepsins and Vaccines for Fascioliosis, Echinococcosis Transmission on the Tibetan Plateau, A Review of Diagnostics for STH from a Public Health Perspective, and Zoonotic Transmission of Intestinal Parasites: Implications for Control and Elimination.
  • Evolution's Clinical Guidebook

    Translating Ancient Genes into Precision Medicine
    • 1st Edition
    • Jules J. Berman
    • English
    Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.
  • Advances in Agronomy

    • 1st Edition
    • Volume 155
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 155, the newest release in this valuable serial, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.
  • The Comorbidities of Epilepsy

    • 1st Edition
    • Marco Mula
    • English
    Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers.
  • Context

    The Effects of Environment on Product Design and Evaluation
    • 1st Edition
    • Herbert L. Meiselman
    • English
    Context: The Effects of Environment on Product Design and Evaluation addresses the environment, or context, in which we consume products and the impact of context on choice and acceptability. The book explores what context is, how it influences design by specialists, and acceptance by consumers. Chapters discuss the basics of context, food and drink in context, testing a range of other products, and other contextual variables. Historically, research on context has been done in the laboratory and various natural locations, but rapid growth in other methods to study context, including evoked contexts, immersive contexts, virtual reality contexts, and more have widened research possibilities. Appealing to the professional, academic and commercial markets, this book will be of interest to those who conduct research in product development and product testing, to those who study what controls product usage, including eating from the health perspective, and to those who make decisions about product and space development.
  • Cadmium Tolerance in Plants

    Agronomic, Molecular, Signaling, and Omic Approaches
    • 1st Edition
    • Mirza Hasanuzzaman + 1 more
    • English
    Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches presents research and latest developments on mechanisms of cadmium tolerance covering both lab and field conditions. This book contains important insights and options for minimizing Cd accumulation in plants and mitigating Cd toxicity. Topics covered include using various omics approaches to understanding plant responses to Cd, novel technologies for developing Cd tolerance and integrated breeding approaches to mitigate Cd stress in crops. Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches is a valuable resource for both researchers and students working on cadmium pollution and plant responses as well as related fields of environmental contamination and toxicology.
  • Sleep and Health

    • 1st Edition
    • Michael A. Grandner
    • English
    Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more.
  • Animal Models in Cancer Drug Discovery

    • 1st Edition
    • Asfar Azmi + 1 more
    • English
    Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.
  • Sex Determination in Vertebrates

    • 1st Edition
    • Volume 134
    • English
    Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more.
  • Evaluation Technologies for Food Quality

    • 1st Edition
    • Jian Zhong + 1 more
    • English
    Evaluation Technologies for Food Quality summarizes food quality evaluation technologies, which include sensory evaluation techniques and chemical and physical analysis. In particular, the book introduces many novel micro and nano evaluation techniques, such as atomic force microscopy, scanning electron microscopy, and other nanomaterial-based methods. All topics cover basic principles, procedures, advantages, limitations, recent technology development, and application progress in different types of foods. This book is a valuable resource for scientists in the field of food science, engineering, and professionals in the food industry, as well as for undergraduate and postgraduate students studying food quality evaluation technology.
  • The Artificial Pancreas

    Current Situation and Future Directions
    • 1st Edition
    • Ricardo S. Sánchez-Peña + 1 more
    • English
    The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient’s quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.
  • Molecular Mechanisms of Dementia

    Biomarkers, Neurochemistry, and Therapy
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists... and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases. 
  • Big Data Analytics for Intelligent Healthcare Management

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data.
  • Ecosystem Consequences of Soil Warming

    Microbes, Vegetation, Fauna and Soil Biogeochemistry
    • 1st Edition
    • Jacqueline E. Mohan
    • English
    Ecosystem Consequences of Soil Warming: Microbes, Vegetation, Fauna and Soil Biogeochemistry focuses on biotic and biogeochemical responses to warmer soils including plant and microbial evolution. It covers various field settings, such as arctic tundra; alpine meadows; temperate, tropical and subalpine forests; drylands; and grassland ecosystems. Information integrates multiple natural science disciplines, providing a holistic, integrative approach that will help readers understand and forecast future planetwide responses to soil warming. Students and educators will find this book informative for understanding biotic and biogeochemical responses to changing climatic conditions. Scientists from a wide range of disciplines, including soil scientists, ecologists, geneticists, as well as molecular, evolutionary and conservation biologists, will find this book a valuable resource in understanding and planning for warmer climate conditions.
  • Mitochondria in Obesity and Type 2 Diabetes

    Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases
    • 1st Edition
    • Beatrice Morio + 2 more
    • English
    Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.
  • Aging, Nutrition and Taste

    Nutrition, Food Science and Culinary Perspectives for Aging Tastefully
    • 1st Edition
    • Jacqueline B. Marcus
    • English
    Approximately 380 million people worldwide are 60 years of age or older. This number is predicted to triple to more than 1 billion by 2025. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully provides research, facts, theories, practical advice and recipes with full color photographs to feed the rapidly growing aging population healthfully. This book takes an integrated approach, utilizing nutrition, food science and the culinary arts. A significant number of aging adults may have taste and smell or chemosensory disorders and many may also be considered to be undernourished. While this can be partially attributed to the behavioral, physical and social changes that come with aging, the loss or decline in taste and smell may be at the root of other disorders. Aging adults may not know that these disorders exist nor what can be done to compensate. This text seeks to fill the knowledge gap. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully examines aging from three perspectives: nutritional changes that affect health and well-being; food science applications that address age-specific chemosensory changes, compromised disease states and health, and culinary arts techniques that help make food more appealing to diminishing senses. Beyond scientific theory, readers will find practical tips and techniques, products, recipes, and menus to increase the desirability, consumption and gratification of healthy foods and beverages as people age.
  • Age Estimation

    A Multidisciplinary Approach
    • 1st Edition
    • Joe Adserias-Garriga
    • English
    Age Estimation: A Multidisciplinary Approach is the only reference in the field covering all techniques and methods involving age estimation from different perspectives in just one volume. The book provides comprehensive coverage of all aspects of age estimation: aging the living and the dead, human rights, and skeletal, dental, histological and biochemical techniques and methods available. Each chapter is written by internationally known expert contributors. Age Estimation: A Multidisciplinary Approach is a one of a kind resource for those involved in estimating the age of the living and the dead.
  • Social Cognition in Psychosis

    • 1st Edition
    • Kathryn Eve Lewandowski + 1 more
    • English
    Social Cognition in Psychosis combines current research on phenotypes, neurobiology, and existing evidence on the assessment and treatment of various forms of psychoses. The book presents various treatment options, including assessment approaches, tools and training methods that aid in the rehabilitation of patients with psychotic disorders. Social cognition is a set of psychological processes related to understanding, recognizing, processing and appropriately using social stimuli in one's environment. Individuals with psychotic disorders consistently exhibit impairments in social cognition. As a result, social cognition has been an important target for intervention, with recent efforts trying to enhance early recovery among individuals with psychotic disorders.
  • Sex Differences in Cardiovascular Physiology and Pathophysiology

    • 1st Edition
    • Babbette LaMarca + 1 more
    • English
    Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.
  • Quorum Sensing

    Molecular Mechanism and Biotechnological Application
    • 1st Edition
    • Giuseppina Tommonaro
    • English
    Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.
  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates

    • 5th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Franklin’s The Mouse Brain in Stereotaxic Coordinates, Fifth Edition, emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience.
  • Caffeinated and Cocoa Based Beverages

    Volume 8. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Caffeinated and Cocoa Based Beverages, Volume Eight in The Science of Beverages series, covers one of the hottest topics in the current beverage industry. This practical reference takes a broad and multidisciplinary approach on the production, processing, and engineering approaches to caffeinated drinks, highlighting their biological impact and health-related interference. The book presents evidence-based examples of the benefits of caffeinated and cocoa-based beverages and analyzes the latest trends in the industry that are essential for researchers in various fields of food and beverage development, including coverage of pharmaceuticals and the biomedical fields.
  • Biomechatronics

    • 1st Edition
    • Marko B. Popovic
    • English
    Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Beginning with an introduction to biomechatronics and its historical background, this book delves into the most groundbreaking recent developments in a wide variety of subjects, such as artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice problems and solutions are provided at the end of the book. Two years in the making, the book Biomechatronics is a result of dedicated work of a team of close to thirty contributors from all across the globe including top researchers and educators from the USA (Popovic, Lamkin-Kennard, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iramina, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle, Willwacher), New Zealand (Liarokapis), and Switzerland (Dobrev).
  • Echinoderms Part B

    • 1st Edition
    • Volume 151
    • English
    Echinoderms, Volume 151, the latest release in the Methods in Cell Biology series, highlights advances in the field, with this update presenting chapters on Echinoderm Genome Databases, analysis of gene regulatory networks, using ATAC-seq and RNA-seq to increase resolution in GRN connectivity, multiplex cis-regulatory analysis, experimental approaches GRN/signal pathways, BACs, analysis of chromatin accessibility using ATAC-seq, analysis of sea urchin proteins /Click IT, CRISPR/Cas9-mediated genome editing in sea urchins, super-resolution and in toto imaging of echinoderm embryos, and methods for analysis of intracellular ion signals in sperm, eggs and embryos.
  • Diagnostic Molecular Biology

    • 1st Edition
    • Chang-Hui Shen
    • English
    Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations. This book also covers the applications of the principles and techniques currently employed in the clinical laboratory.
  • Soilless Culture: Theory and Practice

    Theory and Practice
    • 2nd Edition
    • Michael Raviv + 2 more
    • English
    Soilless Culture: Theory and Practice, Second Edition, is the first authoritative reference book on both the theoretical and practical aspects of growing plants without the use of soil. It is the go-to source for those involved in this practice, focusing on hydroponics and advancements in technologies and methodologies. The book builds on the thorough presentation of both physical and chemical properties of various soilless growing media, also addressing how these properties affect plant performance in basic horticultural operations, such as irrigation and fertilization. In addition, the book describes the latest technical advancements and methodologies, including run-to-waste, re-circulation and closed systems.