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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • The Pathophysiology and Pharmacotherapy of Myocardial Infarction

      • 1st Edition
      • October 22, 2013
      • Nabil El-Sherif + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 8 4 4 9
      • Hardback
        9 7 8 0 1 2 2 3 8 0 4 5 7
      • eBook
        9 7 8 1 4 8 3 2 7 7 1 4 1
      The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

    • Ingredient X

      • 1st Edition
      • October 22, 2013
      • Louis C. Schroeter
      • English
      • Paperback
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      • Hardback
        9 7 8 0 0 8 0 0 6 8 6 2 6
      • eBook
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      Ingredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on drug effectiveness and the role of the pharmaceutical development scientist in designing dosage forms for modern drugs. More than 50 illustrations are used to explain experiments and ""tools of the trade"". This book is comprised of four chapters and opens with an overview of research and development in the pharmaceutical industry, paying particular attention to the kind of work done by scientists according to the degree or level of training. The additives or so-called ""inert"" ingredients used in drug formulation are also considered. The next chapter explains how adding just the right amount of some ""inert"" ingredient—a factor X—can enhance the acceptability of a product to the user. The importance of maintaining drug potency in a dosage form, mainly through refrigeration or storage in cool places, is then discussed. The final chapter looks at the factors to consider to achieve the best possible drug formulation and most effective dosage form, including the safety factor. The need to establish correlations between laboratory quality tests and product performance during the development phase is highlighted. This monograph will be a useful resource for pharmacologists and pharmaceutical development scientists.

    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Frank R. Blood
      • English
      • Paperback
        9 7 8 0 1 2 1 0 7 6 5 2 8
      • eBook
        9 7 8 1 4 8 3 2 1 3 9 7 2
      Essays in Toxicology, Volume 2 covers essays on toxicology and related topics. The book presents essays on fungal toxins, such as mycotoxin, aflatoxin, moldy corn toxicoses, alimentary toxic aleukia, ochratoxin, sporidesmin, zearalenone and other estrogenic compounds, pink rot dermatitis, and slaframine. The text also includes essays on hyperbilirubinemia and cholestasis induced by alpha-naphthylisothi... taurolithocholic acid, and 2-ethyl-2-phenyl butyramide, as different forms of liver injury produced in animals. The evolution of pesticide analyses is also encompassed. Biochemists, physiologists, pathologists, and microbiologists will find the book invaluable.

    • Polydrug Abuse

      • 1st Edition
      • October 22, 2013
      • Donald R. Wesson + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 7 4 5 2 5 0 0
      • Paperback
        9 7 8 1 4 8 3 2 4 8 3 6 3
      • eBook
        9 7 8 1 4 8 3 2 7 6 4 5 8
      Polydrug Abuse: The Results of a National Collaborative Study reports on the findings of a national study of polydrug users, initiated and organized by the Special Action Office of Drug Abuse Prevention. This book provides a comprehensive demographic, sociological, psychological, and medical study of polydrug cases. The chapters in the text cover the varieties and classification of polydrug abusers; an estimation of the magnitude of polydrug abuse; certain central nervous system consequences to chronic drug use; and the impact of polydrug abuse on physicians and other deliverers of health care. Physicians, epidemiologists, drug enforcers, and government policy makers will find the book interesting.

    • Blood

      • 1st Edition
      • October 22, 2013
      • Walter S. Root + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 5 9 5 7 0 5 2
      • Paperback
        9 7 8 1 4 8 3 2 4 5 5 9 1
      • eBook
        9 7 8 1 4 8 3 2 7 2 6 4 1
      Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics are followed by discussions of the mechanism of thrombocytosis and clinical manifestations of thrombocythemia, as well as the mechanisms of immunologic drug effect on blood cells. These parts also explore the effects of drugs on myelopoiesis and the physiological and immunological activities of lymphocytes. The closing part reviews the iron, vitamin B12, folic acid, erythropoietin, and transferrin components of red blood cells. This part also examines the mechanism of erythropoietic cellular proliferation and the initiation of hyperoxia. This book is intended primarily to physiological pharmacologists, hematologists, and researchers.

    • Advances in Drug Research

      • 1st Edition
      • Volume 22
      • October 22, 2013
      • Bernard Testa
      • English
      • Hardback
        9 7 8 0 1 2 0 1 3 3 2 2 2
      • Paperback
        9 7 8 1 4 8 3 2 3 4 9 4 6
      • eBook
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      Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nuclear receptors, emphasizing the aspects of molecular and genomic pharmacology are elaborated in Chapter 3. The last chapter covers the medicinal chemistry of a vast group of agents acting on nuclear receptors. This publication is valuable to drug researchers and students interested in advances in drugs.

    • Cardiac Pharmacology

      • 1st Edition
      • October 22, 2013
      • R. Douglas Wilkerson
      • English
      • Hardback
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      • Paperback
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      • eBook
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      Cardiac Pharmacology aims to interface basic and clinical knowledge of those interventions used or being studied for use in the treatment of heart disease. The book is divided into four major sections which address intrinsic and neural control of cardiac function, pharmacologic modification of cardiac contractility and cardiac output, the genesis and control of cardiac arrhythmias, and pharmacologic manipulation of myocardial oxygen supply and demand. The last three sections contain a chapter describing the techniques employed in the study of that particular aspect of cardiac function and its alterations by pharmacologic interventions. Cardiologists, pharmacologists, physiologists, and those interested in the area of cardiovascular medicine will find the book insightful.

    • Principles, Methods, and General Applications

      • 1st Edition
      • September 11, 2013
      • Gunter Zweig
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 7 3 8 4
      • Hardback
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      Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume 1: Principles, Methods, and General Applications provides information on analytical techniques useful for the determination of pesticides, plant growth regulators, and food additives. The book discusses the potential hazard of minute residues to human and animal health; the principles of formulation and residue analyses; and the principles of food additive analysis. The text also describes the extraction and clean-up procedures; and the principles of toxicological testing methods. The methods for pesticide analysis in meat products; and the formulation and residue analysis in government laboratories are also considered. The book further tackles other methods, such as spectrophotometric methods, chromatography, isotope methods, enzymatic methods; and bioassay. Agricultural toxicologists and people studying pesticides and food additives will find the text invaluable.

    • Neuropsychopharmacology

      • 1st Edition
      • October 22, 2013
      • C. Dumont
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 4 2 3 1
      • eBook
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      Advances in Pharmacology and Therapeutics, Volume 5: Neuropsychopharmacol... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neuropsychopharmacol... and cover topics ranging from anti-schizophrenic drugs to drug pathways in depression treatment. Pharmacological interferences with nonstriatal dopaminergic systems are also discussed. This volume is comprised of 21 chapters and opens by considering the nanomolar affinity of pre- and post-synaptic dopamine receptors for neuroleptics. The next section deals with drug pathways in the treatment of depression, with particular reference to the biochemical mechanisms of depressive states and the therapeutic effects of some antidepressants. The following chapters examine dopamine receptors in the nucleus accumbens; modulation of mesolimbic dopamine mechanisms via serotonin and GABA; how mesocortical dopaminergic neurons react to stress; and the behavioral consequences of the interaction between morphine, substance P, and nonstriatal dopamine neurons. This book will be of interest to practitioners in biosciences, pharmacology, physiology, psychology, neurology, and medicine.

    • Radiation Research

      • 1st Edition
      • October 22, 2013
      • Oddvar F. Nygaard + 2 more
      • English
      • Hardback
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      • eBook
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      Radiation Research: Biomedical, Chemical and Physical Perspectives documents the proceedings of the Fifth International Congress of Radiation Research held in Seattle, Washington, 14-20 July 1974. While the focus of the Congress was on fundamental research, there were several well-attended sessions on the practical aspects of radiation research as it relates to radiotherapy, central station power generation by both nuclear fission and fusion, and the environment. This volume contains 126 papers organized into 31 parts. Beginning with a keynote address and a lecture on the time scale in radiobiology, the subsequent contributions cover a wide range of topics presented over several sessions. Topics discussed during these sessions include energy needs, nuclear power, and the environment; prospects for fusion power; technological applications of radiation; human radiobiology; hazards of radiation exposure relative to other environmental agents; the basic physics of the interactions of radiation with matter; particle penetration phenomena; and radiation effects in frozen media.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation