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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • Abstracts

      • 1st Edition
      • September 11, 2013
      • Sam Stuart
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 2 5 3 0
      Abstracts of the Sixth International Congress of Pharmacology deals with papers submitted during the pharmacology congress held at Helsinki in 1975. This collection of papers deals with research and development in pharmacology and biotherapeutic drugs. The wide array of subjects deals with the therapeutic implications of controlled drug delivery and the methods of drug application, including pharmacological investigations on cell in a culture. The book also contains papers about the interactions of neurotransmitters and the hypothalamic releasing hormones and toxins as tools in receptor studies. Some papers also deal with behavioral pharmacology that covers drug dependence, narcotic analgesics, and anesthetics. The text explains the method seminar concerning animal models simulating pathological conditions. Other papers discuss the pharmacology of emotive behavior with some volunteer papers dealing with subjects of toxicology, neurochemistry, and clinical psychopharmacology. The book also contains papers on cancer chemotherapy, hypertension, neurochemistry, and hematology. One paper evaluates the effects of cardiovascular drugs in humans. This book is suitable for pharmacologists, drug researchers, micro-chemists, oncologists, and specialists in many fields of medicine.

    • Mutagenicity

      • 1st Edition
      • October 22, 2013
      • John A. Heddle
      • English
      • Hardback
        9 7 8 0 1 2 3 3 6 1 8 0 6
      • Paperback
        9 7 8 1 4 8 3 2 4 0 4 5 9
      • eBook
        9 7 8 1 4 8 3 2 7 1 2 2 4
      Mutagenicity: New Horizons in Genetic Toxicology provides an overview of the various applications and studies in the field of genetic toxicology and environmental mutagenesis. The book is composed of selected scientific papers written by experts in the field. The text presents topics on naturally occurring mutagens; occupational carcinogen; and evaluation of cooking methods. Experiments on mammalian cell mutation; chromosomal aberrations; and organisms that can be used as environmental monitors of toxicity are discussed as well. Ecologists, environmental and sanitary engineers, toxicologists, and anyone interested in environmental mutagenesis, genetic toxicology, occupational health, or the regulation of toxic substances will find the book a good source of insight.

    • Neuro-Psychopharmacology

      • 1st Edition
      • October 22, 2013
      • B. Saletu + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 7 3 5 4
      • Hardback
        9 7 8 0 0 8 0 2 3 0 8 9 4
      • eBook
        9 7 8 1 4 8 3 1 5 9 7 7 5
      Neuro-psychopharmaco... covers the proceedings of the 11th Congress of the Collegium Internationale Neuro-psychopharmaco... held in Vienna on July 9-14, 1978. The book focuses on the processes, methodologies, and approaches in neuropsychopharmacol... The selection first offers information on the long-lasting effects of electroconvulsive therapy (ECT) on monoaminergic mechanisms and enhanced monoamine behavioral responses following repeated electroconvulsive shock to rats and their relevance to ECT. The book also underscores the ECT effects on mineral metabolism and neuroendocrine function. The publication reviews the genetic components in the mechanism of action of lithium; genetics and lithium ion metabolism in affective disorders; and pharmacogenetics and the pharmacologic challenge strategy in clinical research. The text also examines the influence of peptides in affective disorders and HLA antigens in affective disorders and cycloid psychoses. Discussions also focus on the biological and clinical basis of the therapeutic effects of benzodiazepines; effects of benzodiazepines on the electrical activity of the central nervous system; and diazepam metabolism in healthy subjects and patients with heart failure, renal failure, and hepatic cirrhosis. The selection is a dependable reference for readers interested in neuropsychopharmacol...

    • The Pathophysiology and Pharmacotherapy of Myocardial Infarction

      • 1st Edition
      • October 22, 2013
      • Nabil El-Sherif + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 8 4 4 9
      • Hardback
        9 7 8 0 1 2 2 3 8 0 4 5 7
      • eBook
        9 7 8 1 4 8 3 2 7 7 1 4 1
      The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

    • Ingredient X

      • 1st Edition
      • October 22, 2013
      • Louis C. Schroeter
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 6 6 9 2
      • Hardback
        9 7 8 0 0 8 0 0 6 8 6 2 6
      • eBook
        9 7 8 1 4 8 3 1 5 9 1 1 9
      Ingredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on drug effectiveness and the role of the pharmaceutical development scientist in designing dosage forms for modern drugs. More than 50 illustrations are used to explain experiments and ""tools of the trade"". This book is comprised of four chapters and opens with an overview of research and development in the pharmaceutical industry, paying particular attention to the kind of work done by scientists according to the degree or level of training. The additives or so-called ""inert"" ingredients used in drug formulation are also considered. The next chapter explains how adding just the right amount of some ""inert"" ingredient—a factor X—can enhance the acceptability of a product to the user. The importance of maintaining drug potency in a dosage form, mainly through refrigeration or storage in cool places, is then discussed. The final chapter looks at the factors to consider to achieve the best possible drug formulation and most effective dosage form, including the safety factor. The need to establish correlations between laboratory quality tests and product performance during the development phase is highlighted. This monograph will be a useful resource for pharmacologists and pharmaceutical development scientists.

    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Frank R. Blood
      • English
      • Paperback
        9 7 8 0 1 2 1 0 7 6 5 2 8
      • eBook
        9 7 8 1 4 8 3 2 1 3 9 7 2
      Essays in Toxicology, Volume 2 covers essays on toxicology and related topics. The book presents essays on fungal toxins, such as mycotoxin, aflatoxin, moldy corn toxicoses, alimentary toxic aleukia, ochratoxin, sporidesmin, zearalenone and other estrogenic compounds, pink rot dermatitis, and slaframine. The text also includes essays on hyperbilirubinemia and cholestasis induced by alpha-naphthylisothi... taurolithocholic acid, and 2-ethyl-2-phenyl butyramide, as different forms of liver injury produced in animals. The evolution of pesticide analyses is also encompassed. Biochemists, physiologists, pathologists, and microbiologists will find the book invaluable.

    • Polydrug Abuse

      • 1st Edition
      • October 22, 2013
      • Donald R. Wesson + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 7 4 5 2 5 0 0
      • Paperback
        9 7 8 1 4 8 3 2 4 8 3 6 3
      • eBook
        9 7 8 1 4 8 3 2 7 6 4 5 8
      Polydrug Abuse: The Results of a National Collaborative Study reports on the findings of a national study of polydrug users, initiated and organized by the Special Action Office of Drug Abuse Prevention. This book provides a comprehensive demographic, sociological, psychological, and medical study of polydrug cases. The chapters in the text cover the varieties and classification of polydrug abusers; an estimation of the magnitude of polydrug abuse; certain central nervous system consequences to chronic drug use; and the impact of polydrug abuse on physicians and other deliverers of health care. Physicians, epidemiologists, drug enforcers, and government policy makers will find the book interesting.

    • Blood

      • 1st Edition
      • October 22, 2013
      • Walter S. Root + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 5 9 5 7 0 5 2
      • Paperback
        9 7 8 1 4 8 3 2 4 5 5 9 1
      • eBook
        9 7 8 1 4 8 3 2 7 2 6 4 1
      Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics are followed by discussions of the mechanism of thrombocytosis and clinical manifestations of thrombocythemia, as well as the mechanisms of immunologic drug effect on blood cells. These parts also explore the effects of drugs on myelopoiesis and the physiological and immunological activities of lymphocytes. The closing part reviews the iron, vitamin B12, folic acid, erythropoietin, and transferrin components of red blood cells. This part also examines the mechanism of erythropoietic cellular proliferation and the initiation of hyperoxia. This book is intended primarily to physiological pharmacologists, hematologists, and researchers.

    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Wayland J. Hayes
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 0 4 1
      • eBook
        9 7 8 1 4 8 3 2 1 6 4 7 8
      Essays in Toxicology, Volume 7 presents essays on toxicology and related topics. The book presents essays on the effects of toxicants on reproductive performance; an overall view of carcinogenesis from an epidemiological viewpoint and the potentialities and limitations of the epidemiological method in cancer control; and the activity of cytochrome P450 and mixed-function oxidase in target and nontarget organisms. The text also includes essays on the toxicity of hexachlorophene and the use of hexachlorophene as an antibacterial agent; the methodology, dose measurement, and respiratory function assessment in respiratory toxicology; as well as behavioral toxicology, with focus on early warning and worker safety and health. Pharmacologists, biochemists, pathologists, neurophysiologists, epidemiologists, and toxicologists will find the book invaluable.

    • Drug Design

      • 1st Edition
      • October 22, 2013
      • E. J. Ariëns
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 6 5 5
      • eBook
        9 7 8 1 4 8 3 2 1 6 0 8 9
      Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals... X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals... and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation