Ingredient X
The Production of Effective Drugs
- 1st Edition - January 1, 1969
- Imprint: Pergamon
- Author: Louis C. Schroeter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 0 6 8 6 2 - 6
- Paperback ISBN:9 7 8 - 1 - 4 8 3 1 - 2 6 6 9 - 2
- eBook ISBN:9 7 8 - 1 - 4 8 3 1 - 5 9 1 1 - 9
Ingredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on… Read more
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Request a sales quoteIngredient X: The Production of Effective Drugs deals with various aspects of pharmaceutical research and development, with emphasis on the importance of formulation ingredients on drug effectiveness and the role of the pharmaceutical development scientist in designing dosage forms for modern drugs. More than 50 illustrations are used to explain experiments and ""tools of the trade"". This book is comprised of four chapters and opens with an overview of research and development in the pharmaceutical industry, paying particular attention to the kind of work done by scientists according to the degree or level of training. The additives or so-called ""inert"" ingredients used in drug formulation are also considered. The next chapter explains how adding just the right amount of some ""inert"" ingredient—a factor X—can enhance the acceptability of a product to the user. The importance of maintaining drug potency in a dosage form, mainly through refrigeration or storage in cool places, is then discussed. The final chapter looks at the factors to consider to achieve the best possible drug formulation and most effective dosage form, including the safety factor. The need to establish correlations between laboratory quality tests and product performance during the development phase is highlighted. This monograph will be a useful resource for pharmacologists and pharmaceutical development scientists.
Preface
Chapter I Research and Development (R & D)
Development
Two Kinds of Research
Training
"Inert" Ingredients
Utility
The Big Cake Bake
A Key Factor
Balancing Act
Growing Old
Tactics and Strategy
Chapter II Product Acceptability
From Tinctures to Tablets
Porous Bottles
How Sweet it is or Who Decides the Taste
Almost Everybody Likes Orange
A Panel Decides
Alas, The Color is Gone
Three Dimensions of Color
Squeezing Tubes and Pouring Goo
The Cream "Feels" Good
A Shot in the Arm
Tablets for Chewing and Swallowing
Chapter II On the Shelf
Purity
Activity
Stockpiles and Doctors' Bags
Early Warning System
Mechanisms and Pathways
Air, Air — Everywhere
Oxygen Scavengers
Lights out
Checking Predictions
Cages for Molecules
Layer Cakes
Bugs
Chapter IV Performance
Safety First
Test Tube Tests
Rockets and Tablets
Hostile Environment
Controlling Release
Absorption
Little Pills
Crossover Tests
Radioactive Labels
Activity and Response
What's Available
Placebo Effects and Clinical Tests
Recipe for Quality
Appendix
Glossary
Index
- Edition: 1
- Published: January 1, 1969
- No. of pages (eBook): 166
- Imprint: Pergamon
- Language: English
- Hardback ISBN: 9780080068626
- Paperback ISBN: 9781483126692
- eBook ISBN: 9781483159119
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