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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • In Vitro Biological Systems

      • 1st Edition
      • October 22, 2013
      • Charles A. Tyson + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 1 8 6 0 1
      Methods in Toxicology, Volume 1: In Vitro Biological Systems, Part A provides basic techniques employed by widely recognized scientists to prepare and maintain the biological components of in vitro model systems. The book discusses the in vitro models of neural and neuromuscular systems; ocular system; respiratory system; cardiovascular system; and gastrointestinal system. The text also describes liver slices; liver hepatocytes; other liver cell systems; proximal tubule fragments; kidney cell culture; reproductive and developmental systems; immune system; and skin. Pharmacologists, toxicologists, cell biologists, physiologists, immunotoxicologists, and molecular toxicologists will find the book invaluable.

    • Toxicology

      • 1st Edition
      • October 22, 2013
      • C. P. Stewart + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 6 6 9 7 0 2 5
      • eBook
        9 7 8 1 4 8 3 2 5 9 7 8 9
      Toxicology: Mechanisms and Analytical Methods, Volume II provides an account of the general methods of chemical analysis available to the toxicologist, discussion of the principles on which they are based, and a survey of the material to which they are applied. The volume supplements the methods presented in the first volume. It provides specific examples of general procedures; considers the important groups of poisons; arranges the order of extraction from biological material; and discusses the methods for identifying and determining the members of each poison group. The book will be invaluable to toxicologists, clinical chemists, and biochemists.

    • The Toxicology of Radioactive Substances

      • 1st Edition
      • October 22, 2013
      • A. A. Letavet + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 0 6 3 8
      • eBook
        9 7 8 1 4 8 3 1 5 3 0 5 6
      The Toxicology of Radioactive Substances, Volume 5: Zinc-65 deals with the toxic properties of the radioisotope zinc-65 as well as its biological effects. Emphasis is placed on the role of stable zinc in the reaction of the body to the administration of zinc-65. Some of the results of laboratory studies on the toxic effects of zinc-65 on animals, primarily rabbits, are presented. This volume is comprised of 18 chapters and opens with an overview of certain aspects of the toxicology of radioactive zinc-65, followed by a discussion on the behavior of zinc-65 in the rat body. Subsequent chapters explore the distribution of zinc-65 in the body of rabbits following chronic oral administration; bioelectrical activity of the cerebral cortex in rabbits in conditions of prolonged administration of radioactive zinc; the effect of prolonged internal irradiation with G5ZnCl2 on the functional state of the rabbit heart; and aspects of hemopoiesis following chronic intake of radiozinc. Morphological changes in experimental animals following chronic exposure to radioactive zinc are also considered. This book will be of interest to chemists and toxicologists.

    • The Toxicology of Radioactive Substances

      • 1st Edition
      • October 22, 2013
      • A. A. Letavet + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 2 8 3
      • eBook
        9 7 8 1 4 8 3 1 4 7 7 0 3
      The Toxicology of Radioactive Substances, Volume 3: Iron-59 deals with the experimental results of tests conducted at the Radiotoxicology Laboratory of the Institute of Occupational Hygiene and Disease, Academy of Medical Sciences, U.S.S.R. The book focuses on studies made on iron-59, which is widely used in science and technology, such as in the metal industry and in the research of hemoglobin metabolism in the bone marrow and red cells. Other studies show, however, that there is a long-term detrimental effect of intake of iron-59. The text then gives a brief outline of the physical, chemical, and biological properties of iron. Research also shows that the body's reaction to radioactive substances depends on how these are transmitted to the body and on their physicochemical properties. The effect of prolonged administration of radioactive iron on the electrical activity of the cerebral cortex of animals is analyzed, of which, possibly, the nervous system is most affected. The book notes also the changes in the red blood cells during chronic administration of iron-59 in small doses, wherein the hemoglobin levels increased temporarily. Studies of prolonged exposure to radioactive isotopes during pregnancy of the test animals show that there are significant changes in erythropoiesis, associated with iron deficiency. In another study, the prolonged internal administration of radioactive substances showed phasic changes in the height of electrocardiographic waves of the test animals. The text is suitable for physicists, nuclear scientists, doctors of toxicology, and researchers in nuclear medicine.

    • The Lung Circulation

      • 1st Edition
      • October 22, 2013
      • Domingo M. Aviado
      • English
      • Hardback
        9 7 8 0 0 8 0 1 0 9 8 8 6
      • Paperback
        9 7 8 1 4 8 3 1 3 3 1 5 7
      • eBook
        9 7 8 1 4 8 3 1 6 5 5 7 8
      The Lung Circulation deals with important aspects of the lung circulation, with emphasis on the physiology of the pulmonary and bronchial circulation and autonomic pharmacology. Topics covered range from the role of anoxia in pulmonary circulation to reflexes arising from the pulmonary circulation and neighboring structures. The release of chemical substances from the pulmonary and bronchial circulation is also discussed. This volume is comprised of 10 chapters and begins with a review of the influence of anoxia on pulmonary circulation as well as four pertinent effects of anoxemia, namely, respiratory stimulation; cardiac stimulation; systemic vasoconstriction and vasodilatation; and pulmonary vasoconstriction and vasodilatation). The following chapters focus on the regulation of bronchial circulation; autonomic nervous control of pulmonary circulation involving acetylcholine, anticholinesterases, and atropine; and the pharmacology of sympathomimetic drugs, sympathetic blocking drugs, ganglion stimulants, and blocking drugs. The final chapter is devoted to the pharmacology of the autonomic nervous system and considers drugs that stimulate chemoreflexes arising from the lung circulation, including veratrum alkaloids. This book will appeal to physiologists and pharmacologists.

    • Evaluating Alcohol and Drug Abuse Treatment Effectiveness

      • 1st Edition
      • October 22, 2013
      • Linda Carter Sobell + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 6 7 5
      • eBook
        9 7 8 1 4 8 3 1 8 8 4 8 5
      Evaluating Alcohol and Drug Abuse Treatment Effectiveness: Recent Advances is a collection of papers that covers the advancement in rehabilitation of individuals with a history of substance abuse. The title aims to find ways in identifying the treatment that best fits a specific patient. The text first provides a historical account of alcohol and drug treatment outcome research. Next, the selection considers the use of multiple measures of life health to assess alcohol treatment. Chapter 3 deals with the behavioral assessment and treatment evaluation of narcotic addiction, while Chapter 4 talks about the evaluation of behavioral and traditional treatment of alcoholics. The fifth chapter tackles the contingency contracting with drug abusers, and the sixth chapter covers the development of a prototype for the evaluation of alcohol treatment. The text also details the problems in alcohol treatment along with the improvement of confidence in treatment of substance abuse. The book will be of great use to behavioral scientists, social workers, and mental health specialists.

    • Fungal Toxins

      • 1st Edition
      • October 22, 2013
      • Solomon Kadis + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 5 3 9 4
      • Hardback
        9 7 8 0 1 2 0 4 6 5 0 8 8
      • eBook
        9 7 8 1 4 8 3 2 5 9 6 8 0
      Microbial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields. The text is divided into three sections. Section A covers coumarins — its isolation, identification, biological action, natural occurrence, and uses. Section B deals with the epizootiology, clinical characteristics, and pathological findings of Stachybotryotoxicosi... Section C talks about phytopathogenic and helminthosporium toxins, toxic peptides found in Amanita species as well as other mushroom toxins, compounds accumulating in plants after an infection, and ergot. The book is recommended for microbiologists and toxicologists, especially those who would like to know more about the toxins produced by algae and fungi and their effects.

    • Drug Design

      • 1st Edition
      • October 22, 2013
      • E. J. Ariëns
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 6 2 4
      • eBook
        9 7 8 1 4 8 3 2 1 6 0 5 8
      Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.

    • Marihuana Biological Effects

      • 1st Edition
      • October 22, 2013
      • Gabriel G. Nahas + 1 more
      • English
      • Hardback
        9 7 8 0 0 8 0 2 3 7 5 9 6
      • Paperback
        9 7 8 1 4 8 3 1 2 5 6 2 6
      • eBook
        9 7 8 1 4 8 3 1 5 8 0 4 4
      Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held at Paris on July 22-23, 1978. Organized into four parts, this book begins with a discussion on the quantification of cannabinoids and their metabolites in the body fluids and tissues. Part II describes the cannabinoids and cellular metabolism. Parts III and IV explain the effects of cannabis on reproduction and brain.

    • Criteria (Dose/Effect Relationships) for Organochlorine Pesticides

      • 1st Edition
      • October 22, 2013
      • M. Mercier
      • English
      • eBook
        9 7 8 1 4 8 3 1 3 7 5 0 6
      Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides. Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product. This book is a valuable resource for agriculturists and research workers.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation