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Toxicology
Mechanisms and Analytical Methods
- 1st Edition - January 1, 1961
- Editors: C. P. Stewart, A. Stolman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 6 6 9 7 0 2 - 5
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 5 9 7 8 - 9
Toxicology: Mechanisms and Analytical Methods, Volume II provides an account of the general methods of chemical analysis available to the toxicologist, discussion of the principles… Read more
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Request a sales quoteToxicology: Mechanisms and Analytical Methods, Volume II provides an account of the general methods of chemical analysis available to the toxicologist, discussion of the principles on which they are based, and a survey of the material to which they are applied. The volume supplements the methods presented in the first volume. It provides specific examples of general procedures; considers the important groups of poisons; arranges the order of extraction from biological material; and discusses the methods for identifying and determining the members of each poison group. The book will be invaluable to toxicologists, clinical chemists, and biochemists.
Contents
Contributors to Volume II
Foreword
Preface
Contents of Volume I
1. The Mode of Action of Poisons
I. Introduction
II. Enzyme Inhibition
III. Factors which Influence Inhibition and Its Effects
IV. Further Examples of Enzyme Inhibition; Antidotes
V. Conclusion
References
2. Gases, Vapors, Mists, and Dusts
I. The Importance of Contaminated Atmosphere in Industrial Hygiene
II. Biochemical Control of Exposure
III. The Determination of Toxic Substances in the Atmosphere
References
3. Identification and Estimation of Volatile Poisons
I. Introduction
II. Qualitative Tests
III. Quantitative Procedures
References
4. Ethyl Alcohol
I. Pure Alcohol and Alcoholic Beverages
II. "Normal" Alcohol
III. Absorption of Alcohol
IV. Distribution of Absorbed Alcohol
V. Fate of Absorbed Alcohol
VI. Pharmacological and Toxicological Effects
VII. Determination of Alcohol in Body Materials; General Considerations
VIII. Directions for Five Methods of Estimating Alcohol in Body Tissues and Fluids
IX. Breath Alcohol Methods
X. Medicolegal Interpretation of the Level of Blood Alcohol
References
5. Barbiturates
I. Isolation
II. Identification
III. Quantitative Determination of Barbiturates
IV. Interpretation of Results
V. Conclusion
References
6. Acidic and Neutral Poisons (Other than Barbiturates)
I. Introduction
II. Isolation
III. Purification
IV. Identification
V. Conclusion
References
7. Alkaloids and Related Bases: Identification
I. General Introduction
II. Separation and Purification
III. Identification and Determination
IV. Biotransformations
Tables
Appendix: The Discoveries of Some Alkaloids and Related Substances, Their Tests, and the Chronological Development of Toxicology
References
8. Acids and Alkalies
I. Mineral Acids
II. Organic Acids
III. Mineral Alkalies
References
9. Chemical Tests for Metallic Poisons
I. Reinsch Test
II. Marsh-Berzelius Test
III. Gutzeit Test
IV. Dithizone Method
V. Special Methods for Determination of Antimony, Barium, Chromium, Cobalt, Gold, Lithium, Manganese, Mercury, and Thallium
References
10. Analysis of Residual Pesticides in Food
I. Introduction
II. Physical Methods
III. Cleanup and Result of Chemical Changes in the Pesticide
IV. Enzymatic Methods of Analysis
V. The Importance of Metabolites
VI. Nonspecific Methods for Chlorinated Organic Pesticides
VII. Qualitative Tests for Rapid Identification of Chlorinated Pesticides
VIII. Quantitative Determination of the Chloride Ion
IX. Specific Methods for Chlorinated Pesticides
X. The Cyclodiene Insecticides
XI. Organic Phosphorus Pesticides
XII. Analytical Methods for Organic Phosphorus Pesticides
XIII. Carbamates
XIV. Dithiocarbamates
XV. Organic Pesticides Containing a CN Radical
XVI. Organic Pesticides Containing a Thiocyanate Radical
XVII. Determination of Dinitroaromatic Pesticides
XVIII. Determination of Dinitroaromatic Compounds
XIX. Miscellaneous Pesticides
Appendix A: Partial List of Important Halogenated Compounds and Mixtures Used as Pesticides
Appendix B: Some Important Organic Phosphorus Pesticides
References
11. Poisonous Plants
I. Introduction
II. Chemical Ontogeny and Taxonomic Distribution
III. Methods of Identification
References
12. Radioactive Isotopes and Compounds
I. Introduction
II. Nuclear Energy and Radioactivity
III. Interaction of Radiation with Matter
IV. Sources of Exposure and Contact
V. Radioactive Waste Disposal
VI. Dosage Rate and Distribution
VII. Methods of Detection and Measurement
VIII. Pharmacology and Mechanism of Action
IX. Handling and Disposal of Bodies and Tissues Containing Radioactive Materials
X. Pathology; Acute and Chronic Effects of Various Organ Systems
XL Medicolegal Interpretation
References
13. Miscellaneous Determinations
I. Hemoglobin Derivatives
II. Halides
III. Porphyrins
IV. Glucuronic Acid
References
14. The Treatment of Acute Poisoning
I. Introduction
II. Removal and Inactivation of the Poison
III. Symptomatic Treatment
IV. Plan of Treatment of a Case of Acute Poisoning
V. Notes on Individual Poisons and Special Therapeutic Measures
List of Poisons Discussed
References
Subject Index
- No. of pages: 938
- Language: English
- Edition: 1
- Published: January 1, 1961
- Imprint: Academic Press
- Hardback ISBN: 9780126697025
- eBook ISBN: 9781483259789