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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

    • Antibiotic Resistance and Nanotherapy

      • 1st Edition
      • Awanish Kumar + 1 more
      • English
      Antibiotic Resistance and Nanotherapy is a comprehensive guide that takes an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. The book also tackles the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, Antibiotic Resistance and Nanotherapy is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance
    • How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms

      From Bench to the Clinics
      • 1st Edition
      • Neelam Poonia + 2 more
      • English
      How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms: From Bench to the Clinics is an essential guide providing a comprehensive roadmap for transitioning complex injectable formulations from the laboratory to clinical applications. Offering an in-depth exploration of various complex injectables, including liposomal dosage forms, nanoparticles, and microspheres, this book delves into the principles of dosage form design, excipient selection, stability studies, and optimization techniques. Readers will gain valuable insights into ensuring the stability, efficacy, and safety of injectables during the scale-up process, as well as strategies for maintaining product quality and consistency from lab-scale to commercial-scale production. The book thoroughly examines manufacturing technologies such as aseptic processing, sterile filtration, and lyophilization, and their applications in producing complex injectables. Detailed discussions on quality control measures, analytical techniques, and quality assurance practices are provided to ensure the consistent quality and purity of injectables throughout the manufacturing process. Readers will benefit from the expert knowledge and practical insights shared by industry professionals and leading researchers, including successful examples of marketed complex injectables. Highlighting best practices and regulatory requirements, this book offers a comprehensive overview of the guidelines for the development, manufacturing, and commercialization of complex injectables. Discussions on Good Manufacturing Practices (GMP) and regulatory submissions underscore the importance of compliance in achieving successful product development. Ideal for pharmaceutical scientists, formulation developers, and regulatory professionals, this book is a valuable resource for anyone involved in the scale-up and commercialization of complex injectable dosage forms.
    • Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

      • 1st Edition
      • Harish Dureja + 5 more
      • English
      Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies—inc... polymeric nanoparticles, liposomes, and theranostic nanoparticles—this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.
    • Fundamentals and Design of Drug Delivery Systems

      A Textbook with Lab Activities
      • 1st Edition
      • Wujie Zhang
      • English
      Fundamentals and Design of Drug Delivery Systems: A Textbook with Lab Activities is an essential resource for pharmaceutical sciences and engineering students. Covering all key concepts related to drug delivery courses, it introduces basic pharmacology, barriers to drug delivery, drug targeting, and novel drug delivery systems. Design considerations and approaches are thoroughly illustrated. The textbook reflects nanotechnology in various chapters and includes practical lab activities, providing a comprehensive understanding of drug delivery systems, experimental design, and data analysis. It is ideally suited for upper-undergraduate and graduate courses.In addition to the foundational material, the textbook delves into cutting-edge topics such as biomimetic drug delivery systems, targeted delivery systems, stimuli-responsive systems, and micro/nano-robots-ba... drug delivery systems. Emerging fields like cell therapy, artificial intelligence (AI) in drug delivery, and 3D printing-based systems are also explored. Professionals in the Pharma industry will benefit from the innovative concepts and platforms presented, making it a valuable addition to their resources.
    • Handbook of Pharmaceutical Wet Granulation

      Theory and Practice in a Quality by Design Paradigm
      • 2nd Edition
      • Ajit S. Narang + 1 more
      • English
      Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm, Second Edition offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. This completely revised and updated edition features five new chapters covering new AI tools applied to scaling up granulation processes, model drive design, machine learning models for granule property prediction, design and scale up of fluid bed granulation, and process analytical methods. This book is the prefect reference for pharmaceutical manufacturing professionals. Academic researchers will benefit from the practical advice provided by the editors and chapter authors.
    • Functionalized Drug Delivery Systems

      • 1st Edition
      • Umesh Gupta + 1 more
      • English
      Functionalized Drug Delivery Systems delves into the potential of various functionalized drug delivery systems, such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS. It offers a comprehensive guide from basic concepts to advanced surface engineering techniques. The book covers liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes, and ethosomes, concluding with a chapter on the regulatory framework. This invaluable resource is perfect for pharmaceutical researchers and graduate students keen on advancing their understanding and application of these innovative drug delivery methods. The book also provides consolidated literature reviews, making it a foundational text for new researchers.Its chapters are dedicated to specific techniques, offering detailed insights into each method. Readers will gain knowledge on improving drug absorption and targeted delivery, supported by practical examples and case studies. The final chapter on regulatory frameworks ensures compliance and best practices in developing functionalized drug delivery systems. This book is an essential read for anyone in the field of pharmaceutical research.
    • Harnessing Endogenous Mechanisms for Targeted Drug Delivery

      • 1st Edition
      • Anisha A. D’Souza + 2 more
      • English
      Harnessing Endogenous Mechanisms for Targeted Drug Delivery explores the cutting-edge advancements in the world of targeted drug delivery leveraging human biological mechanisms. This essential guide addresses the urgent need to enhance the efficiency of drug delivery and foster safe and effective therapies, particularly for biological agents like proteins, peptides, and nucleic acid molecules. The book offers a comprehensive exploration of tissue- and cell-specific delivery methods, emphasizing endogenous or biological techniques that can be utilized to improve drug delivery. It identifies the challenges associated with delivering complex molecules and accessing hard-to-reach sites, and provides practical solutions through endogenous strategies. Topics such as exploiting disease-specific stimuli to enhance delivery efficiency, the role of plasma proteins in drug delivery, and the utilization of extracellular vesicles to boost delivery efficiency are presented. Harnessing Endogenous Mechanisms for Targeted Drug Delivery emphasizes the clinical and commercial translation of these techniques, making this book an ideal resource for researchers, clinicians, and anyone interested in the future of drug delivery.
    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 47
      • English
      Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 47, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird’s Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more.Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much much more.
    • Inorganic Biomaterials for Drug Delivery

      • 1st Edition
      • Amit Kumar Nayak + 2 more
      • English
      Inorganic Biomaterials for Drug Delivery covers a wide range of inorganic biomaterial types and their properties, from traditional materials like ceramics, metallics, and bioglasses to novel composites and nano-engineered inorganic biomaterials. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.
    • Dissipative Particle Dynamics

      Fundamentals and Applications in Soft Matter Science and Engineering
      • 1st Edition
      • Alexander V. Neimark + 1 more
      • English
      Dissipative Particle Dynamics: Fundamentals and Applications in Soft Matter Science and Engineering comprehensively presents the fundamentals of dissipative particle dynamics (DPD) theoretical formulations and computational strategies, providing practical guidance on the application of DPD models to various colloidal and interfacial phenomena involving phase separations, self-assembly and transport in complex fluids, polymeric, surfactant, nanoparticle, and biological systems. In addition, the book contains instructive advice on efficient implementation of the DPD models in open-source computational packages. Since the introduction of the principles of DPD methodology, multiple efforts have been made to improve the computational basis of DPD, and to devise advanced versions and modifications. There are numerous research papers on this topic, but no books until now. Readers will find this to be a comprehensive reference source of multifaceted, interdisciplinary applications that provides practical guidance for efficient computational implementation.