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Books in Pharmacotherapy

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Drug Delivery Systems for Wound Healing

  • 1st Edition
  • December 2, 2024
  • Pedro Fonte + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 8 4 0 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 0 8 1 - 2
Drug Delivery Systems for Wound Healing explores the different delivery systems and drugs used in wound healing, outlining the many pharmaceutical approaches in wound healing and management. Bringing together interdisciplinary research on wound healing and management, this book offers the theory behind wound healing, but also has a strong focus on the practical approach where scientists involved in medication development can find suggestions. Where appropriate, clinical outcomes are given so the book can be useful as a guide for the choice by medication prescription or use.Topics in the book include types of drugs used in wound healing; types of carriers used in wound healing; clinical outcomes; biocompatibility and toxicity problems, and pipeline products. Researchers working in the pharmaceutical sciences, biomedical sciences and engineering fields will find this a useful resource.

Polymer-Drug Conjugates

  • 1st Edition
  • July 5, 2023
  • Jitender Madan + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 6 6 3 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 6 9 0 - 5
Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

Formulation of Monoclonal Antibody Therapies

  • 1st Edition
  • May 20, 2023
  • Amal Ali Elkordy
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 3 6 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 4 2 8 - 0
Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies, and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. It also covers the industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases, and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences.

Advanced Nanoformulations

  • 1st Edition
  • March 22, 2023
  • Md Saquib Hasnain + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 7 8 5 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 8 5 7 9 - 9
Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications.

Global Perspectives on Astaxanthin

  • 1st Edition
  • April 9, 2021
  • Gokare A. Ravishankar + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 3 0 4 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 3 0 5 - 4
Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications explores the range of practical applications for this molecule, focusing on nutraceutical, pharmaceutical and cosmeceutical products, along with food and feed. This volume brings together the most relevant research, background and future thinking on astaxanthin, focusing on its health benefits. Chapters cover phytopharmaceuticals, industrial production, feeds, downstream processing, regulations, products, color, pigment, cosmetics, bioactive compounds, relationships to other carotenoids, and skin care. The detailed information on its production, processing, utilization and future applications will be of particular use to academic and industry researchers in pharmaceutical sciences, pharmacology and nutrition.

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

  • 1st Edition
  • March 15, 2021
  • Mariappan Rajan
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 9 9 8 5 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 4 4 8 4 - 5
A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.

Taxaceae and Cephalotaxaceae

  • 1st Edition
  • January 5, 2021
  • Da-Cheng Hao
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 9 7 5 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 4 2 3 6 - 0
Taxaceae and Cephalotaxaceae: Biodiversity, Chemodiversity, and Pharmacotherapy accounts for the biodiversity and chemodiversity of these medicinal plants, examining and synthesizing existing research into their biology, chemistry and pharmacotherapy. The title examines how pharmacophylogeny allows sustainable conservation and exploitation, presents how these plants work from the chemical level upward, and examines associated microbe compounds. Chapters present a summary of biological and biochemical research of Taxaceae plants, progress in mining their chemodiversity, mining pharmacotherapy utility from their chemodiversity and biodiversity, drug metabolism and pharmacokinetic diversity of their medicinal compounds, mining pharmacotherapy utility from associated microbes, and more. Sections cover the biodiversity, chemodiversity and pharmacotherapy of Cephalotaxus medicinal plants, Amentotaxus, Pseudotaxus and Torreya medicinal plants. The book envisages that multiple omics platforms and advanced systems biology will allow further exploration of Taxaceae and Cephalotaxaceae, thus streamlining the future drug supply chain.

Considering the Patient in Pediatric Drug Development

  • 1st Edition
  • November 19, 2020
  • Klaus Rose
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 8 8 8 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 4 2 0 5 - 6
Considering the Patient in Pediatric Drug Development: How Good Intentions Turned into Harm addresses a fundamental challenge in drug development and healthcare for young patients. In clinical trials and clinical practice, the term "children" is used ambiguously to confer physiological characteristics to a chronological age limit, which in reality does not exist. This book outlines why the United States (US) and European Union's (EU) regulatory authorities, pediatric academia, and the pharmaceutical industry demand, support and perform pediatric drug studies, along with the key flaws of this demand that blurs the different administrative and physiological meanings of the term "child." In addition, the book covers why most pediatric regulatory studies lack medical sense and many even harm young patients and the conflicts of interest behind pediatric drug studies. It includes relevant information about the maturation of the human body regarding absorption, distribution, metabolism and excretion of food and drugs as well as key differences between newborns, infants, older children and adolescents.

Preparation of Phytopharmaceuticals for the Management of Disorders

  • 1st Edition
  • November 3, 2020
  • Chukwuebuka Egbuna + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 0 2 8 4 - 5
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 0 2 8 5 - 2
Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful.

Combination Therapy Against Multidrug Resistance

  • 1st Edition
  • April 30, 2020
  • Mohmmad Younus Wani + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 0 5 7 6 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 0 5 7 8 - 5
Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant